Kathy Nguyen

College of Sciences

Works (5)

Updated: April 5th, 2024 13:00

2023 review

Tolyporphins-Exotic Tetrapyrrole Pigments in a Cyanobacterium-A Review

[Review of ]. MOLECULES, 28(16).

By: K. Nguyen n, Y. Zhang n, Q. Liu n, R. Zhang n, X. Jin  n, M. Taniguchi n , E. Miller n , J. Lindsey n 

author keywords: bacteriochlorin; bioinformatics; biosynthesis; chlorophyll; cyanobacteria; field biology; gene cluster; genomics; natural products; tolyporphins
TL;DR: The identification of putative biosynthetic gene clusters in the HT-58-2 cyanobacterial genome and accompanying studies suggest a new biosynthesis paradigm in the tetrapyrrole arena, which stands alone in the large pigments-of-life family. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 2, 2023

2022 journal article

Tailoring the AIE Chromogen 2-(2-Hydroxyphenyl)benzothiazole for Use in Enzyme-Triggered Molecular Brachytherapy

MOLECULES, 27(24).

By: Z. Wu n, J. Dou n, K. Nguyen n, J. Eppley  n, K. Siwawannapong n, Y. Zhang n, J. Lindsey n 

author keywords: aggregation; cancer; insolubilization; molecular design; phosphodiester; precipitation; radiotherapy
MeSH headings : Prodrugs; Brachytherapy; Benzothiazoles; Polyethylene Glycols
TL;DR: Several 2-(2-hydroxyphenyl)benzothiazole substrates that readily aggregate in aqueous solution (and afford AIE) were elaborated, taking a step forward on the long road toward molecular brachytherapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 17, 2023

2021 article

Fluorescence Assay for Tolyporphins Amidst Abundant Chlorophyll in Crude Cyanobacterial Extracts

Nguyen, K.-U., Zhang, R., Taniguchi, M., & Lindsey, J. S. (2021, July 16). PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 7.

By: K. Nguyen n, R. Zhang n, M. Taniguchi n  & J. Lindsey n 

Contributors: K. Nguyen n, R. Zhang n, M. Taniguchi n  & J. Lindsey n 

MeSH headings : Chlorophyll / chemistry; Chlorophyll A; Cyanobacteria / chemistry; Fluorescence; Spectrometry, Fluorescence
TL;DR: Tolyporphins were readily detected in cultures of HT‐58‐2 at reasonable growth periods in the absence of environmental stressors, which was not possible previously. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 26, 2021

2021 journal article

Identification of Putative Biosynthetic Gene Clusters for Tolyporphins in Multiple Filamentous Cyanobacteria

LIFE-BASEL, 11(8).

By: X. Jin n, Y. Zhang n, R. Zhang n, K. Nguyen n, J. Lindsey n  & E. Miller n 

author keywords: tolyporphins; tetrapyrroles; cyanobacteria; biosynthetic gene cluster; Brasilonema; Nostoc; Oculatella
TL;DR: Phylogenetic analysis based on 16S rRNA and a common component of the BGCs, TolD, points to a close evolutionary history between each strain and their respective tolyporphins BGC, and a collection of candidate cyanobacteria for genetic and biochemical analysis pertaining to these unusual tetrapyrrole macrocycles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 7, 2021

2020 journal article

Engineering of an archaeal phosphodiesterase to trigger aggregation-induced emission (AIE) of synthetic substrates

NEW JOURNAL OF CHEMISTRY, 44(33), 14266–14277.

By: Y. Zhang n, Z. Wu n, I. Takashima  n, K. Nguyen n, N. Matsumoto n & J. Lindsey n 

TL;DR: The development of enzymatically triggered substrates and the complementary heterologous enzymes may support diverse applications in the life sciences. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 14, 2020

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