Vladimir Aleksandrovich Pozdin

Works (13)

Updated: February 17th, 2025 07:37

2025 article

Light-Controlled Peptide Ligands for the Photoaffinity Purification of FLT3 and CD38

Moore, B. D., Prodromou, R., Rusch, G. P., Nguyen, C., Chu, W., Pozdin, V., … Menegatti, S. (2025, January 31). ACS APPLIED ENGINEERING MATERIALS, Vol. 1.

By: B. Moore n, R. Prodromou n, G. Rusch n, C. Nguyen n, W. Chu n, V. Pozdin*, M. Daniele n , S. Menegatti n 

author keywords: azobenzene-cyclic peptides; affinity ligands; photoaffinity chromatography; biorecognition; cellmarkers
Sources: Web Of Science, NC State University Libraries
Added: February 10, 2025

2023 review

Advances in Modeling and Interpretability of Deep Neural Sleep Staging: A Systematic Review

[Review of ]. PHYSIOLOGIA, 4(1), 1–42.

By: R. Soleimani n, J. Barahona n, Y. Chen n , A. Bozkurt n, M. Daniele n , V. Pozdin*, E. Lobaton n 

author keywords: sleep stage classification; EEG; ECG; deep learning; contrastive learning; transfer learning; data augmentation; interpretability
TL;DR: An improvement in performance up to 12% on standard datasets over the last 5 years is identified and the causes for these trends seem to be caused by incorporating new architectural components, such as the use of transformers and contrastive learning. (via Semantic Scholar)
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16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 1, 2024

2023 article

Conformal Micropatterned Organic-Metal Electrodes for Physiological Recording

2023 IEEE SENSORS.

By: K. Queener n , P. Ahmmed n , M. Victorio*, J. Twiddy n, A. Dehn n, A. Brewer n, E. Lobaton n , A. Bozkurt n, V. Pozdin*, M. Daniele n 

author keywords: conformal electrodes; biopotential recording; microfabrication; photolithography; PEDOT:PSS
TL;DR: CMOM electrodes were characterized then evaluated in vivo against commercial-off-the-shelf electrodes and PEDOT:PSS coating found to reduce the overall impedance in each electrode variant, resulting in a >97% decrease in impedance at low frequencies. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 1, 2024

2023 journal article

Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 16(5), 823–846.

By: K. Rivera n, R. Bilton, J. Burclaff n , M. Czerwinski *, J. Liu *, J. Trueblood*, C. Hinesley *, K. Breau * ...

author keywords: Inflammatory Hypoxia; Microphysiological System; Intestinal Stem Cells; Stem Cell Priming; Oxygen Sensor; Cytokines
TL;DR: A new microphysiological system (MPS) is presented to investigate how hypoxia affects hISCs from healthy donors and test the hypothesis that prolongedHypoxia modulates how hISC respond to inflammation-associated interleukins (ILs) and has important implications for understanding intestinal epithelial regeneration mechanisms caused by inflammatory hypoxIA. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 6, 2023

2023 journal article

Molecular Engineering of Cyclic Azobenzene‐Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo‐Affinity Chromatography

Advanced Functional Materials, 33(14).

By: R. Prodromou n, B. Moore n, W. Chu n, H. Deal n, A. San Miguel n , A. Brown n , M. Daniele n , V. Pozdin*, S. Menegatti n 

author keywords: affinity ligands; azobenzene-peptide hybrids; biomolecular recognition; factor VIII; photo-affinity chromatography
TL;DR: The cyclic azobenzene‐peptide ligands introduced in this report demonstrate a novel route integrating gentle operational conditions in a rapid and efficient bioprocess for the purification of life‐saving biotherapeutics. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: February 20, 2023

2022 article

Towards Wearable Health Monitoring DevicesY

Pozdin, V. A., & Dieffenderfer, J. (2022, May). BIOSENSORS-BASEL, Vol. 12.

By: V. Pozdin* & J. Dieffenderfer n

MeSH headings : Humans; Wearable Electronic Devices
Source: Web Of Science
Added: June 13, 2022

2021 journal article

Engineering Next Generation Cyclized Peptide Ligands for Light-Controlled Capture and Release of Therapeutic Proteins

ADVANCED FUNCTIONAL MATERIALS, 31(27).

By: R. Prodromou n, K. Day n, S. Saberi-Bosari n, J. Schneible n, M. Mabe  n, A. San Miguel n , M. Daniele n , V. Pozdin*, S. Menegatti n 

author keywords: azobenzene; cyclized peptide; light‐ controlled biorecognition; microfluidic devices; photochromic switch; photo‐ isomerization kinetics
TL;DR: A framework for prototyping photo‐affinity adsorbents comprising azobenzene‐cyclized peptides (ACPs) conjugated to translucent porous beads (ChemMatrix) and it is demonstrated that the isomerization at different light intensities is correlated to the cyclization geometry. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 24, 2021

2021 journal article

Monitoring of random microvessel network formation by in-line sensing of flow rates: A numerical and in vitro investigation

SENSORS AND ACTUATORS A-PHYSICAL, 331.

By: V. Pozdin*, P. Erb n, M. Downey n, K. Rivera n & M. Daniele n 

author keywords: Microphysiological systems; Microfluidics; Equivalent circuit; Fluid mechanics; Vascular mechanics; Microvessels; Fluid networks
TL;DR: A strategy to monitor the dynamic formation of microscale fluid networks, which can be translated to the monitoring of microvasculature development in engineered tissue constructs and illustrates the potential to precisely and non-destructively monitor microvessel network development and volumetric changes. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 18, 2021

2020 journal article

Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides

JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413–7427.

By: K. Day n, J. Schneible n, A. Young n, V. Pozdin*, G. Driessche  n, L. Gaffney n, R. Prodromou n, D. Freytes n ...

MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
TL;DR: This study demonstrates a general method to develop azobenzene-cyclized peptide ligands with light-controlled affinity for target proteins by designing photo-switchable peptides targeting vascular cell adhesion marker 1 (VCAM1), a cell marker implicated in stem cell function. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 14, 2020

2020 journal article

Wearable multiplexed biosensor system toward continuous monitoring of metabolites

BIOSENSORS & BIOELECTRONICS, 153.

By: M. Yokus n, T. Songkakul n , V. Pozdin n, A. Bozkurt n & M. Daniele n 

author keywords: Wearable; Multiplex; Potentiostat; Electrochemical sensors; Glucose; Lactate; pH; Sweat sensors
MeSH headings : Biosensing Techniques / instrumentation; Dimethylpolysiloxanes / chemistry; Electrochemical Techniques; Electrodes; Glucose / analysis; Humans; Hydrogen-Ion Concentration; Lactic Acid / analysis; Metabolome / physiology; Monitoring, Physiologic / instrumentation; Skin Temperature; Surface Properties; Sweat / chemistry; Wearable Electronic Devices
TL;DR: The design and characterization of a wearable system with a flexible sensor array for non-invasive and continuous monitoring of human biochemistry and future evaluation of temporal changes of the sweat biomarkers is reported. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: March 23, 2020

2019 review

Measuring and regulating oxygen levels in microphysiological systems: design, material, and sensor considerations

[Review of ]. ANALYST, 144(10), 3190–3215.

By: K. Rivera n, M. Yokus n, P. Erb n, V. Pozdin n & M. Daniele n 

MeSH headings : Animals; Cell Line; Humans; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Models, Biological; Oxygen / analysis; Oxygen / metabolism
TL;DR: Comparisons of organ-specific MPS that do and do not consider oxygen microenvironments are offered and materials used in microphysiological models are analyzed in terms of their ability to control oxygen. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 22, 2019

2019 journal article

Perylene-diimide-based n-type semiconductors with enhanced air and temperature stable photoconductor and transistor properties

DYES AND PIGMENTS, 174.

By: J. Yuen *, V. Pozdin n, A. Young n, B. Turner n, I. Giles *, J. Naciri*, S. Trammell *, P. Charles*, D. Stenger *, M. Daniele n 

author keywords: Perylene; n-type; Photoconductor; Field effect transistor; Air stable
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7. Affordable and Clean Energy (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 17, 2020

2018 journal article

Integrated phosphorescence-based photonic biosensor (iPOB) for monitoring oxygen levels in 3D cell culture systems

BIOSENSORS & BIOELECTRONICS, 123, 131–140.

By: K. Rivera n, V. Pozdin n, A. Young n, P. Erb n, N. Wisniewski*, S. Magness n, M. Daniele n 

author keywords: Oxygen; Microdevice; Organs-on-chips; Oxygen biosensor; Biosensors; Hypoxia
MeSH headings : Biosensing Techniques; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Humans; Luminescent Measurements / methods; Oxygen / chemistry; Oxygen / metabolism; Photons
TL;DR: The design and engineering of a system to remotely monitor and control oxygen concentration inside a device for 3D cell culture is reported, integrating a photonic oxygen biosensor into the 3D tissue scaffold and regulate oxygen concentration via the control of purging gas flow. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 3, 2018

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