Works (5)

Updated: July 5th, 2023 14:34

2021 journal article

Systematic metabolome profiling and multi-omics analysis of the nitrogen-limited non-model oleaginous algae for biorefining

BIOFUEL RESEARCH JOURNAL-BRJ, 8(1), 1330-+.

By: V. Rai n, S. Patel*, M. Muthuraj*, M. Gandhi*, D. Das* & S. Srivastava*

author keywords: Chlorella sp. FC2 IITG; Metabolomic profiling; Multi-omics analysis; Nitrogen-limitation; Time-course study; Biodiesel
TL;DR: Multiomics data unraveled a metabolic tug-of-war ongoing between biomass and storage lipid (TAG) accumulation during nitrogen-limitation, which involved multiple processes including hindered CO2 fixation, the supply of energy, reductants, and carbon reallocation from proteins and membrane lipids. (via Semantic Scholar)
Source: Web Of Science
Added: March 29, 2021

2020 review

Artificial Intelligence to Decode Cancer Mechanism: Beyond Patient Stratification for Precision Oncology

[Review of ]. FRONTIERS IN PHARMACOLOGY, 11.

By: S. Patel*, B. George* & V. Rai n

author keywords: multi-omics; artificial intelligence (AI); data integration; cancer biomarkers; patient stratification
TL;DR: This review highlights critical advances and challenges in omics data analysis, dealing with data variability from lab-to-lab, and data integration, and describes methods used in data mining and AI methods to obtain robust results for precision medicine from “big” data. (via Semantic Scholar)
Source: Web Of Science
Added: September 21, 2020

2020 journal article

Extraction and Detection of Structurally Diverse Siderophores in Soil

FRONTIERS IN MICROBIOLOGY, 11.

By: V. Rai n, N. Fisher n, O. Duckworth n & O. Baars n

author keywords: siderophores; extraction; recovery; iron; soil; adsorption; alpha-hydroxycarboxylate; catecholate
TL;DR: Using the optimized extraction method, α-hydroxycarboxylate type siderophores were detected in soil for the first time and concentrations reached 461 pmol g–1, suggesting a yet unrecognized importance of α- Hydroxamate desferrioxamine B and rhizoferrin for biological interactions and biogeochemical processes in soil. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2020 review

Immune Dysfunction and Multiple Treatment Modalities for the SARS-CoV-2 Pandemic: Races of Uncontrolled Running Sweat?

[Review of ]. BIOLOGY-BASEL, 9(9).

author keywords: COVID-19; adoptive cell-based therapy; immunomodulatory drugs; cytokine storm; extracellular vesicles; anti-neoplastic regimen; mesenchymal stem cells
TL;DR: High-performance multi-directory strategies describing the uncontrolled deregulation of the host immune landscape associated with coronavirus disease (COVID-19) and treatment strategies using an anti-neoplastic regimen are discussed. (via Semantic Scholar)
Source: Web Of Science
Added: November 9, 2020

2020 review

Untargeted Metabolomics Workshop Report: Quality Control Considerations from Sample Preparation to Data Analysis

[Review of ]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 31(9), 2006–2010.

By: P. Phapale*, V. Rai n, A. Mohanty* & S. Srivastava*

author keywords: untargeted metabolomics; workshop report; LC-MS/MS analysis; quality control
TL;DR: Three main topics from the Metabolomics workshop are reviewed, which were uniquely identified as bottlenecks for new researchers: experimental design, quality controls during sample preparation and instrumental analysis, and data quality evaluation using open source tools. (via Semantic Scholar)
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Source: Web Of Science
Added: October 5, 2020

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