Wenning Chu

Works (8)

Updated: April 11th, 2023 10:13
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2023 journal article

Development of peptide affinity ligands for the purification of polyclonal and monoclonal Fabs from recombinant fluids

JOURNAL OF CHROMATOGRAPHY A, 1687.

By: R. Kilgore, W. Chu, D. Bhandari*, D. Fischler*, R. Carbonell, M. Crapanzano*, S. Menegatti 

author keywords: Peptide ligands; Affinity chromatography; Fragment antigen binding; Monoclonal antibodies; Cell culture harvests
Sources: Web Of Science, ORCID
Added: January 17, 2023

2023 article

Molecular Engineering of Cyclic Azobenzene-Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo-Affinity Chromatography

Prodromou, R., Moore, B. D., Chu, W., Deal, H., San Miguel, A., Brown, A. C., … Menegatti, S. (2023, January 25). ADVANCED FUNCTIONAL MATERIALS, Vol. 1.

By: R. Prodromou, B. Moore, W. Chu, H. Deal, A. San Miguel , A. Brown, M. Daniele, V. Pozdin, S. Menegatti 

author keywords: affinity ligands; azobenzene-peptide hybrids; biomolecular recognition; factor VIII; photo-affinity chromatography
Sources: Web Of Science, ORCID
Added: February 20, 2023

2022 journal article

De novo discovery of peptide-based affinity ligands for the fab fragment of human immunoglobulin G

JOURNAL OF CHROMATOGRAPHY A, 1669.

By: X. Xiao, R. Kilgore, S. Sarma, W. Chu, S. Menegatti  & C. Hall 

author keywords: Affinity ligands; Ligand design; Biorecognition; Protein chromatography; Fragment antigen binding
Sources: Web Of Science, ORCID
Added: May 2, 2022

2022 journal article

Development of peptide ligands for the purification of a-1 antitrypsin from cell culture fluids

JOURNAL OF CHROMATOGRAPHY A, 1679.

By: W. Chu, R. Prodromou, B. Moore, D. Elhanafi, R. Kilgore, S. Shastry, S. Menegatti 

author keywords: a-1 antitrypsin; Peptide ligands; Affinity chromatography; Protein purification; CHO cell culture harvest
Sources: Web Of Science, ORCID
Added: October 11, 2022

2022 article

Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents

Sripada, S. A., Chu, W., Williams, T. I., Teten, M. A., Mosley, B. J., Carbonell, R. G., … Menegatti, S. (2022, April 22). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 119.

By: S. Sripada, W. Chu, T. Williams , M. Teten n, B. Mosley n, R. Carbonell, A. Lenhoff *, S. Cramer * ...

author keywords: CHO; flow-through chromatography; host cell proteins; monoclonal antibodies; peptide-based adsorbents
Sources: Web Of Science, ORCID
Added: April 10, 2022

2021 journal article

Peptides and pseudopeptide ligands: a powerful toolbox for the affinity purification of current and next-generation biotherapeutics

JOURNAL OF CHROMATOGRAPHY A, 1635.

By: W. Chu, R. Prodromou, K. Day, J. Schneible, K. Bacon, J. Bowen n, R. Kilgore, C. Catella ...

author keywords: Affinity ligands; peptides; peptoids; pseudopeptides; biotherapeutics
Sources: Web Of Science, ORCID
Added: January 25, 2021

2021 article

Purification of polyclonal immunoglobulin G from human serum using peptide-based adsorbents

Chu, W., Sripada, S. A., Reese, H. R., Bhandari, D., Adams, A., Sly, J., … Menegatti, S. (2021, October 20). AICHE JOURNAL, Vol. 10.

By: W. Chu, S. Sripada, H. Reese, D. Bhandari*, A. Adams n, J. Sly*, M. Crapanzano*, S. Menegatti 

author keywords: affinity ligands; LigaGuard (TM); LigaTrap (TM); polyclonal antibodies; protein chromatography
Sources: Web Of Science, ORCID
Added: November 1, 2021

2021 journal article

Removal of host cell proteins from cell culture fluids by weak partitioning chromatography using peptide-based adsorbents

SEPARATION AND PURIFICATION TECHNOLOGY, 257.

By: R. Lavoie  n, W. Chu, J. Lavoie, Z. Hetzler n, T. Williams , R. Carbonell, S. Menegatti 

author keywords: Host cell proteins; Monoclonal antibodies; Flow-through chromatography; Weak partitioning mode; Polishing; Proteomics; Peptide ligands
Sources: Web Of Science, ORCID
Added: January 11, 2021