William Huggins

Works (3)

Updated: July 13th, 2023 21:16

2020 journal article

A dual-therapy approach for the treatment of biofilm-mediated Salmonella gallbladder carriage

PLOS PATHOGENS, 16(12).

By: J. Sandala *, B. Eichar*, L. Kuo *, M. Hahn *, A. Basak *, W. Huggins n, K. Woolard *, C. Melander *, J. Gunn *

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Asymptomatic Infections; Biofilms / drug effects; Carrier State / microbiology; Gallbladder / microbiology; Mice; Salmonella Infections, Animal; Salmonella typhi / drug effects; Typhoid Fever
TL;DR: Two unique small molecules capable of both inhibiting Salmonella biofilm growth and disrupting pre-formed biofilm structures without affecting bacterial viability are identified and suggested as a dual-therapy approach targeting both biofilm and planktonic populations can be further developed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 25, 2021

2018 journal article

2-Aminobenzimidazoles as antibiofilm agents against Salmonella enterica serovar Typhimurium

MEDCHEMCOMM, 9(9), 1547–1552.

By: W. Huggins n, T. Nguyen  n, N. Hahn n, J. Baker n, L. Kuo *, D. Kaur*, R. Melander  n, J. Gunn *, C. Melander  n

TL;DR: Modifications to the head, tail, and linker regions of the original hit compound elucidated new, more effective analogues that inhibit S. enterica serovar Typhimurium biofilm formation while being non-toxic to planktonic bacterial growth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: November 12, 2018

2017 journal article

Electrolyte-sensing transistor decals enabled by ultrathin microbial nanocellulose

Scientific Reports, 7.

By: J. Yuen, S. Walper, B. Melde, M. Daniele & D. Stenger

Source: NC State University Libraries
Added: August 6, 2018

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