Works (18)

2022 article

Relationship between hearing, cognitive function, and quality of life in aging companion dogs

Fefer, G., Khan, M. Z., Panek, W. K., Case, B., Gruen, M. E., & Olby, N. J. (2022, August 6). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 8.

By: G. Fefer, M. Khan, W. Panek, B. Case, M. Gruen & N. Olby

author keywords: canine cognitive dysfunction syndrome; CCDS; cognitive testing; dementia; presbycusis
Sources: Web Of Science, ORCID
Added: August 22, 2022

2022 journal article

Use of Cognitive Testing, Questionnaires, and Plasma Biomarkers to Quantify Cognitive Impairment in an Aging Pet Dog Population

JOURNAL OF ALZHEIMERS DISEASE, 87(3), 1367–1378.

author keywords: Blood biomarkers; canine cognitive dysfunction syndrome; CCDS; cognitive testing; dementia; neurofilament light chain; NfL
Sources: Web Of Science, ORCID
Added: June 20, 2022

2021 journal article

Computed tomography findings in a cohort of 169 dogs with elbow dysplasia-a retrospective study

BMC VETERINARY RESEARCH, 17(1).

By: M. Hebel*, W. Panek, J. Ruszkowski*, M. Nabzdyk*, D. Niedzielski*, K. Pituch*, A. Jackson*, M. Kielbowicz*, M. Pomorska-Mol*

author keywords: Canine elbow dysplasia; CED; CT; Imaging; Dogs
Sources: Web Of Science, ORCID
Added: September 20, 2021

2021 journal article

Plasma Amyloid Beta Concentrations in Aged and Cognitively Impaired Pet Dogs

MOLECULAR NEUROBIOLOGY, 58(2), 483–489.

By: W. Panek, D. Murdoch*, M. Gruen, F. Mowat, R. Marek* & N. Olby

author keywords: Canine; Cognitive dysfunction; Alzheimer's disease; CDS; Amyloid beta 42; Amyloid beta 40
Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 journal article

BET inhibition increases βIII-tubulin expression and sensitizes metastatic breast cancer in the brain to vinorelbine

Science Translational Medicine, 12(558).

By: D. Kanojia*, W. Panek, A. Cordero*, J. Fares*, A. Xiao*, S. Savchuk*, K. Kumar*, T. Xiao* ...

Source: ORCID
Added: October 31, 2021

2020 journal article

GCN2 is essential for CD8+ T cell survival and function in murine models of malignant glioma

Cancer Immunology, Immunotherapy, 69(1), 81–94.

By: A. Rashidi*, J. Miska*, C. Lee-Chang*, D. Kanojia*, W. Panek, A. Lopez-Rosas*, P. Zhang*, Y. Han* ...

author keywords: GCN2; CD8(+) T-cell; Glioma; ISRIB
Source: ORCID
Added: October 31, 2021

2020 journal article

Plasma Neurofilament Light Chain as a Translational Biomarker of Aging and Neurodegeneration in Dogs

MOLECULAR NEUROBIOLOGY, 57(7), 3143–3149.

By: W. Panek, M. Gruen, D. Murdoch*, R. Marek*, A. Stachel, F. Mowat, K. Saker, N. Olby

author keywords: Canine; Cognitive dysfunction; Alzheimer's disease; Amyotrophic lateral sclerosis; Degenerative myelopathy
Sources: Web Of Science, ORCID
Added: July 13, 2020

2019 journal article

FABP7 is a key metabolic regulator in HER2+ breast cancer brain metastasis

Oncogene, 38(37), 6445–6460.

By: A. Cordero*, D. Kanojia*, J. Miska*, W. Panek, A. Xiao*, Y. Han*, N. Bonamici*, W. Zhou* ...

Source: ORCID
Added: October 31, 2021

2019 journal article

HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

Cell Reports, 27(1), 226–237.e4.

Source: ORCID
Added: October 31, 2021

2019 journal article

Local Application of Autologous Platelet-Rich Fibrin Patch (PRF-P) Suppresses Regulatory T Cell Recruitment in a Murine Glioma Model

Molecular Neurobiology, 56(7), 5032–5040.

By: W. Panek, K. Pituch*, J. Miska*, J. Kim*, A. Rashidi*, D. Kanojia*, A. Lopez-Rosas*, Y. Han* ...

author keywords: Glioblastoma multiforme; Immunosuppressive microenvironment; Platelet-rich fibrin patch; Regulatory Tcells and glioma immune therapies
Source: ORCID
Added: October 31, 2021

2019 journal article

Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

Proceedings of the National Academy of Sciences of the United States of America, 116(47), 23714–23723.

By: P. Zhang*, J. Miska*, C. Lee-Chang*, A. Rashidi*, W. Panek, S. An*, M. Zannikou*, A. Lopez-Rosas* ...

author keywords: immunotherapy; glioblastoma; myeloid cell; PD-L1; radiotherapy
Source: ORCID
Added: October 31, 2021

2018 journal article

A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model

Neurotherapeutics, 15(4), 1127–1138.

By: J. Kim*, J. Kane*, W. Panek, J. Young*, A. Rashidi*, D. Yu*, D. Kanojia*, T. Hasan* ...

author keywords: glioblastoma; adenovirus; dendritic cells; cytomegalovirus; vaccine
Source: ORCID
Added: October 31, 2021

2018 journal article

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma

Molecular Therapy, 26(4), 986–995.

By: K. Pituch*, J. Miska*, G. Krenciute*, W. Panek, G. Li*, T. Rodriguez-Cruz*, M. Wu*, Y. Han* ...

Source: ORCID
Added: October 31, 2021

2018 chapter

Gene/Viral Treatment Approaches for Malignant Brain Cancer

In Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy: Second Edition (pp. 211–227).

By: J. Kim*, K. Pituch*, A. Xiao*, J. Young*, W. Panek, M. Muroski*, A. Rashidi*, J. Kane*, D. Kanojia*, M. Lesniak*

Source: ORCID
Added: October 31, 2021

2017 journal article

A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model

Molecular Therapy - Oncolytics, 5, 97–104.

By: J. Kim*, J. Miska*, J. Young*, A. Rashidi*, J. Kane*, W. Panek, D. Kanojia*, Y. Han*, I. Balyasnikova*, M. Lesniak*

Source: ORCID
Added: October 31, 2021

2017 journal article

Hitting the nail on the head: Combining oncolytic adenovirusmediated virotherapy and immunomodulation for the treatment of glioma

Oncotarget, 8(51), 89391–89405.

author keywords: combinatory therapy; glioma; immunomodulator(s); checkpoint blockade; oncolytic adenovirus
Source: ORCID
Added: October 31, 2021

2017 journal article

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

Proceedings of the National Academy of Sciences of the United States of America, 114(30), E6147–E6156.

By: D. Yu*, O. Khan*, M. Suvà*, B. Dong*, W. Panek, T. Xiao*, M. Wu*, Y. Han* ...

author keywords: siRNA; lipopolymeric nanoparticle; glioblastoma transcription factor; brain tumor-initiating cells; convection-enhanced delivery
Source: ORCID
Added: October 31, 2021

2017 journal article

Multiplexed nanomedicine for brain tumors: Nanosized Hercules to tame our Lernaean Hydra inside?

Nanomedicine, 12(20), 2435–2439.

By: W. Panek, O. Khan*, D. Yu* & M. Lesniak*

author keywords: GBM; nanoparticle; nanomedicine; brain tumor; siRNA; convection enhanced delivery; BTIC/brain tumor-initiating cells; stem cell transcription factor
Source: ORCID
Added: October 31, 2021

Employment

2020 - 2023

University of California Davis Davis, CA, US
Small Animal Neurology/Neurosurgery Resident Surgical and CLinical Sciences