Wesley Legant

Works (9)

Updated: August 12th, 2023 05:00

2023 journal article

Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics


By: E. Doherty n, W. Aw n, E. Warren n, M. Hockenberry*, C. Whitworth*, G. Krohn n, S. Howell*, B. Diekman n ...

author keywords: Vascular Ehlers-Danlos syndrome; Cell derived matrix; Collagen III; Mechanotransduction; ECM mechanics; Viscoelasticity
Source: Web Of Science
Added: August 7, 2023

2022 journal article

A quantitative analysis of various patterns applied in lattice light sheet microscopy


By: Y. Shi n, T. Daugird* & W. Legant n

MeSH headings : Microscopy; Normal Distribution; Photobleaching
Source: Web Of Science
Added: August 29, 2022

2022 article

Cells in the mechanical spotlight

Hockenberry, M. A., & Legant, W. R. (2022, October 4). BIOPHYSICAL JOURNAL, Vol. 121, pp. 3571–3572.

By: M. Hockenberry & W. Legant*

Source: Web Of Science
Added: November 28, 2022

2022 journal article

Superresolution microscopy reveals actomyosin dynamics in medioapical arrays


By: R. Moore n, S. Fogerson*, U. Tulu*, J. Yu*, A. Cox*, M. Sican*, D. Li*, W. Legant n ...

MeSH headings : Actin Cytoskeleton / metabolism; Actins / metabolism; Actomyosin / metabolism; Animals; Drosophila / metabolism; Microscopy; Myosins / metabolism
Source: Web Of Science
Added: October 24, 2022

2021 article

A multi-functional microfluidic device compatible with widefield and light sheet microscopy

Moore, R. P., Ellen C. O'Shaughnessy, Shi, Y., Nogueira, A. T., Heath, K. M., Hahn, K. M., & Legant, W. R. (2021, November 22). LAB ON A CHIP.

By: R. Moore n, . Ellen C. O'Shaughnessy*, Y. Shi n, A. Nogueira*, K. Heath n, K. Hahn*, W. Legant n

MeSH headings : Lab-On-A-Chip Devices; Lenses; Microfluidics; Microscopy; Refractometry
Source: Web Of Science
Added: December 13, 2021

2021 article

Deep learning enables fast and dense single-molecule localization with high accuracy

Speiser, A., Mueller, L.-R., Hoess, P., Matti, U., Obara, C. J., Legant, W. R., … Turaga, S. C. (2021, September 3). NATURE METHODS.

MeSH headings : Animals; COS Cells; Chlorocebus aethiops; Databases, Factual; Deep Learning; Image Processing, Computer-Assisted / methods; Single Molecule Imaging / methods; Software
Source: Web Of Science
Added: September 13, 2021

2021 article

Phase separation drives aberrant chromatin looping and cancer development

Ahn, J. H., Davis, E. S., Daugird, T. A., Zhao, S., Quiroga, I. Y., Uryu, H., … Wang, G. G. (2021, June 23). NATURE.

By: J. Ahn*, E. Davis*, T. Daugird*, S. Zhao*, I. Quiroga*, H. Uryu*, J. Li*, A. Storey* ...

MeSH headings : Animals; Carcinogenesis; Chromatin / genetics; Female; HEK293 Cells; HeLa Cells; Homeodomain Proteins / genetics; Humans; Intrinsically Disordered Proteins / genetics; Mice; Mice, Inbred BALB C; Neoplasms / genetics; Neoplasms / pathology; Nuclear Pore Complex Proteins / genetics; Oncogene Proteins, Fusion / genetics; Transcription Factors / genetics; Transcriptional Activation; Translocation, Genetic
Source: Web Of Science
Added: July 6, 2021

2019 journal article

High-resolution imaging reveals how the spindle midzone impacts chromosome movement

JOURNAL OF CELL BIOLOGY, 218(8), 2529–2544.

By: M. Pamula*, L. Carlini*, S. Forth*, P. Verma*, S. Suresh*, W. Legant n, A. Khodjakoy, E. Betzig*, T. Kapoor*

MeSH headings : Anaphase; Cell Cycle Proteins / metabolism; Chromosome Segregation; Chromosomes, Human / metabolism; Fluorescence Recovery After Photobleaching; HeLa Cells; Humans; Imaging, Three-Dimensional; Microtubule-Associated Proteins / metabolism; Microtubules / metabolism; Movement; Mutation / genetics; Spindle Apparatus / metabolism
Source: Web Of Science
Added: August 19, 2019

2018 article

Improving probes for super-resolution

Moore, R. P., & Legant, W. R. (2018, September). NATURE METHODS, Vol. 15, pp. 659–660.

By: R. Moore n & W. Legant n

MeSH headings : DNA; Microscopy, Fluorescence; Oligonucleotides
Source: Web Of Science
Added: October 19, 2018