William R Atchley
Works (37)
Updated: July 12th, 2023 21:14
2012 journal article
A novel N-terminal domain may dictate the glucose response of Mondo proteins
PLoS One, 7(4).
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Evolution of the Max and Mlx Networks in Animals
GENOME BIOLOGY AND EVOLUTION, 3, 915–937.
author keywords: protein evolution; basic-helix-loop-helix-leucine zipper (bHLHZ) domain; Myc/Max/Mad network; Mlx and Mondo Network; phylogenetic tree; discriminant analysis
MeSH headings : Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / chemistry; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics; Basic-Leucine Zipper Transcription Factors / classification; Basic-Leucine Zipper Transcription Factors / genetics; Binding Sites; Evolution, Molecular; Gene Expression Regulation; Gene Regulatory Networks / genetics; Humans; Molecular Sequence Data; Multigene Family; Phylogeny; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Synteny / genetics
academic.oup.com (publisher PDF)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Joint analysis of transcriptional and post-transcriptional brain tumor data: searching for emergent properties of cellular systems
BMC Bioinformatics, 12.
Source: NC State University Libraries
Added: August 6, 2018
2011 article
Walter M. Fitch (1929-2011)
Atchley, W. R. (2011, May 13). SCIENCE, Vol. 332, pp. 804–804.
MeSH headings : Evolution, Molecular; History, 20th Century; History, 21st Century; Periodicals as Topic / history; Societies, Scientific / history; Societies, Scientific / organization & administration; United States
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Biochemical and functional evidence of p53 homology is inconsistent with molecular phylogenetics for distant sequences
JOURNAL OF MOLECULAR EVOLUTION, 67(1), 51–67.
author keywords: p53; p63; p73; beta-Sandwich; transcription factor; p731
MeSH headings : Animals; Arthropods / genetics; DNA-Binding Proteins / classification; Evolution, Molecular; Genes, p53; Mollusca / genetics; Nematoda / genetics; Nuclear Proteins / classification; Phylogeny; Sequence Homology, Amino Acid; Tumor Protein p73; Tumor Suppressor Protein p53 / chemistry; Tumor Suppressor Protein p53 / classification; Tumor Suppressor Proteins / classification; Urochordata / genetics
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Hepatic endopolyploidy as a cellular consequence of age-specific selection for rate of development in mice
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, 310B(5), 385–397.
MeSH headings : Aging / genetics; Aging / pathology; Animals; Female; Flow Cytometry; Growth; Liver / metabolism; Liver / pathology; Male; Mice; Mice, Inbred ICR; Polyploidy
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Site-specific evolutionary rates in proteins are better modeled as non-independent and strictly relative
BIOINFORMATICS, 24(19), 2177–2183.
MeSH headings : Algorithms; Animals; Basic-Leucine Zipper Transcription Factors / chemistry; Basic-Leucine Zipper Transcription Factors / genetics; Computational Biology; Databases, Protein; Evolution, Molecular; Genes, myc; Humans; Proteins / chemistry; Proteins / genetics; Sequence Alignment; Tumor Suppressor Protein p53 / chemistry; Tumor Suppressor Protein p53 / genetics
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Application of complex demodulation on bZIP and bHLH-PAS protein domains
Mathematical Biosciences, 207(2), 204–218.
MeSH headings : Algorithms; Amino Acid Motifs; Amino Acid Sequence; Aryl Hydrocarbon Receptor Nuclear Translocator / chemistry; Basic Helix-Loop-Helix Transcription Factors / chemistry; Basic-Leucine Zipper Transcription Factors / chemistry; Computational Biology / methods; Databases, Protein; Entropy; Factor Analysis, Statistical; Fourier Analysis; Humans; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos / chemistry
Source: NC State University Libraries
Added: August 6, 2018
2007 journal article
Molecular architecture of the DNA-binding region and its relationship to classification of basic helix-loop-helix proteins
MOLECULAR BIOLOGY AND EVOLUTION, 24(1), 192–202.
author keywords: computational biology; bHLH proteins; molecular architecture; multivariate statistics; DNA-binding specificity; molecular evolution
MeSH headings : Animals; Basic Helix-Loop-Helix Transcription Factors / chemistry; Basic Helix-Loop-Helix Transcription Factors / classification; Basic Helix-Loop-Helix Transcription Factors / genetics; Basic Helix-Loop-Helix Transcription Factors / metabolism; Binding Sites; Codon / genetics; DNA / metabolism; Dimerization; Humans; Hydrophobic and Hydrophilic Interactions; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Networks of coevolving sites in structural and functional domains of serpin proteins
MOLECULAR BIOLOGY AND EVOLUTION, 22(7), 1627–1634.
author keywords: serpin; factor analysis; coevolution; covariation; protein structure; mutual information
MeSH headings : Amino Acids / chemistry; Animals; Crystallography, X-Ray; Evolution, Molecular; Factor Analysis, Statistical; Multivariate Analysis; Phylogeny; Protein Conformation; Protein Folding; Protein Structure, Secondary / genetics; Sequence Analysis, Protein; Serine Proteinase Inhibitors; Serpins / chemistry; Serpins / physiology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Sequence signatures and the probabilistic identification of proteins in the Myc-Max-Mad network
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6401–6406.
author keywords: Myc; predictive motif; transcription factor; oncoprotein; molecular evolution
MeSH headings : Amino Acid Sequence / genetics; Basic-Leucine Zipper Transcription Factors; Computational Biology / methods; DNA-Binding Proteins / genetics; Fuzzy Logic; Genetic Variation; Genomics / methods; Helix-Loop-Helix Motifs / genetics; Molecular Sequence Data; Protein Conformation; Proto-Oncogene Proteins c-myc / genetics; Repressor Proteins / genetics; Sequence Alignment; Sequence Homology; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Solving the protein sequence metric problem
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6395–6400.
author keywords: basic helix-loop-helix; molecular evolution; multivariate statistics; amino acid attributes; factor analysis
MeSH headings : Amino Acid Sequence / genetics; Analysis of Variance; Cluster Analysis; Codon / genetics; Computational Biology / methods; Discriminant Analysis; Genetic Variation; Models, Genetic; Multivariate Analysis; Phylogeny; Protein Conformation; Static Electricity; Statistics as Topic / methods
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Phylogenetic analysis of plant basic helix-loop-helix proteins
Journal of Molecular Evolution, 56(6), 742–750.
MeSH headings : Amino Acid Sequence; Arabidopsis / genetics; Genome, Plant; Helix-Loop-Helix Motifs; Molecular Sequence Data; Multigene Family; Oryza / genetics; Phylogeny; Plant Proteins / chemistry; Plant Proteins / genetics; Transcription Factors / chemistry; Transcription Factors / genetics
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Origin of the black shank resistance gene, Ph, in tobacco cultivar Coker 371-gold
PLANT DISEASE, 86(10), 1080–1084.
author keywords: disease resistance genes; gene phylogeny
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Phylogenetic analyses of amino acid variation in the serpin proteins
MOLECULAR BIOLOGY AND EVOLUTION, 18(8), 1502–1511.
author keywords: serpins; molecular evolution; phylogeny; protein evolution; maximum likelihood; neighbor joining
MeSH headings : Amino Acids / genetics; Animals; Databases, Factual; Evolution, Molecular; Exons; Genes / genetics; Genetic Variation; Humans; Introns; Phylogeny; Serpins / genetics
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Vertebrate serpins: Construction of a conflict-free phylogeny by combining exon-intron and diagnostic site analyses
MOLECULAR BIOLOGY AND EVOLUTION, 18(4), 577–584.
author keywords: molecular evolution; serpins; exon-intron structure; diagnostic sites; heparin cofactor II
MeSH headings : Amino Acid Sequence / genetics; Animals; Exons / genetics; Humans; Introns / genetics; Models, Statistical; Multigene Family; Phylogeny; Serine Proteinase Inhibitors / classification; Serine Proteinase Inhibitors / genetics; Serpins / classification; Serpins / genetics
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Body weight and tail length divergence in mice selected for rate of development
JOURNAL OF EXPERIMENTAL ZOOLOGY, 288(2), 151–164.
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Cellular consequences in the brain and liver of age-specific selection for rate of development in mice
Genetics, 155(3), 1347–1357.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Characterization and differential expression of a human gene family of olfactomedin-related proteins
GENETICAL RESEARCH, 76(1), 41–50.
MeSH headings : Amino Acid Sequence; Animals; Blotting, Northern; Brain / metabolism; Cytoskeletal Proteins; Extracellular Matrix Proteins / biosynthesis; Extracellular Matrix Proteins / genetics; Eye Proteins / biosynthesis; Eye Proteins / genetics; Gene Expression; Glycoproteins / biosynthesis; Glycoproteins / genetics; Humans; Molecular Sequence Data; Multigene Family; Phylogeny; Rats; Sequence Homology, Amino Acid; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Correlations among amino acid sites in bHLH protein domains: An information theoretic analysis
MOLECULAR BIOLOGY AND EVOLUTION, 17(1), 164–178.
author keywords: mutual information; protein evolution; entropy; parametric bootstrap; helix-loop-helix
MeSH headings : Amino Acids / chemistry; Amino Acids / genetics; Animals; Evolution, Molecular; Helix-Loop-Helix Motifs / genetics; Humans; Models, Theoretical; Transcription Factors / chemistry; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Differential longevity in mouse stocks selected for early life growth trajectory
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 55(9), B455–B461.
MeSH headings : Adenocarcinoma / physiopathology; Adenoma / physiopathology; Aging / genetics; Aging / physiology; Animals; Body Constitution; Body Weight; Cause of Death; Female; Fibrosarcoma / physiopathology; Forecasting; Heart Failure / physiopathology; Longevity / genetics; Longevity / physiology; Lymphoma / physiopathology; Male; Mice; Mice, Inbred ICR / genetics; Mice, Inbred ICR / growth & development; Random Allocation; Regression Analysis; Weight Gain
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Effect of long-term selection for early postnatal growth rate on survival and prenatal development of transferred mouse embryos
Journal of Reproduction & Fertility, 118(1), 205–210.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Molecular evolution of the GATA family of transcription factors: Conservation within the DNA-binding domain
JOURNAL OF MOLECULAR EVOLUTION, 50(2), 103–115.
author keywords: GATA; transcription factor; zinc finger; DNA binding domain; phylogeny; Boltzmann entropy; predictive motif
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Conserved Sequence; DNA-Binding Proteins / physiology; Erythroid-Specific DNA-Binding Factors; Evolution, Molecular; Models, Molecular; Molecular Sequence Data; Phylogeny; Protein Structure, Tertiary; Transcription Factors / physiology; Zinc Fingers
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Separation of phylogenetic and functional associations in biological sequences by using the parametric bootstrap
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(7), 3288–3291.
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Effect of selection for development rate on reproductive onset in female mice
GENETICAL RESEARCH, 74(1), 55–64.
MeSH headings : Age Factors; Analysis of Variance; Animals; Female; Mice; Mice, Inbred ICR; Reproduction / genetics; Selection, Genetic; Sexual Maturation / genetics; Weight Gain / genetics
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Evolution of bHLH transcription factors: Modular evolution by domain shuffling?
MOLECULAR BIOLOGY AND EVOLUTION, 16(12), 1654–1663.
author keywords: modular evolution; molecular evolution; basic helix-loop-helix domain; transcription factors; sequence alignment; phylogeny
MeSH headings : DNA-Binding Proteins / genetics; Evolution, Molecular; Helix-Loop-Helix Motifs / genetics; Phylogeny; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Molecular evolution of helix-turn-helix proteins
JOURNAL OF MOLECULAR EVOLUTION, 49(3), 301–309.
author keywords: helix-turn-helix; homology; phylogeny; transcription factors; sequence shuffling
MeSH headings : Amino Acid Sequence; Conserved Sequence; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; Evolution, Molecular; Helix-Turn-Helix Motifs; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors / chemistry; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Positional dependence, cliques, and predictive motifs in the bHLH protein domain
JOURNAL OF MOLECULAR EVOLUTION, 48(5), 501–516.
author keywords: basic helix-loop-helix proteins; bHLH; information theory; Boltzmann entropy; predictive motifs; positional dependence; cliques
MeSH headings : Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Transcription Factors; Binding Sites / genetics; Conserved Sequence; DNA / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Evolution, Molecular; Helix-Loop-Helix Motifs / genetics; Humans; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Transcription Factors / chemistry; Transcription Factors / genetics; Transcription Factors / metabolism
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Uterine and postnatal maternal effects in mice selected for differential rate of early development
Genetics, 153(2), 905–917.
Source: NC State University Libraries
Added: August 6, 2018
1998 journal article
Molecular evolution of the Myb family of transcription factors: Evidence for polyphyletic origin
JOURNAL OF MOLECULAR EVOLUTION, 46(1), 74–83.
author keywords: Myb; evolution; phylogeny; transcription factors; oncogene
MeSH headings : Animal Population Groups / physiology; Animals; Binding Sites; Evolution, Molecular; Models, Biological; Phylogeny; Plant Physiological Phenomena; Protein Conformation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Repetitive Sequences, Nucleic Acid; Trans-Activators / chemistry; Trans-Activators / genetics; Transcription Factors / chemistry; Transcription Factors / physiology
Source: Web Of Science
Added: August 6, 2018
1997 journal article
A natural classification of the basic helix-loop-helix class of transcription factors
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 94(10), 5172–5176.
MeSH headings : Amino Acid Sequence; Animals; Evolution, Molecular; Genetic Variation; Helix-Loop-Helix Motifs; Humans; Molecular Sequence Data; Phylogeny; Point Mutation; Sequence Homology, Amino Acid; Transcription Factors / chemistry; Transcription Factors / classification; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
1997 journal article
Altering developmental trajectories in mice by restricted index selection
Genetics, 146(2), 629–640.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Developmental quantitative genetics, conditional epigenetic variability and growth in mice
Genetics, 147(2), 765–776.
Source: NC State University Libraries
Added: August 6, 2018
1994 journal article
DEVELOPMENTAL QUANTITATIVE GENETIC MODELS OF EVOLUTIONARY CHANGE
DEVELOPMENTAL GENETICS, 15(1), 92–103.
author keywords: DEVELOPMENTAL QUANTITATIVE GENETICS; DEVELOPMENT; EPIGENETIC; EVOLUTION; GENETIC MODELS; EFFECTS
MeSH headings : Animals; Biological Evolution; Growth / genetics; Models, Genetic; Multivariate Analysis
Source: Web Of Science
Added: August 6, 2018
1993 journal article
Genetic affinities of inbred mouse strains of uncertain origin
Molecular Biology and Evolution, 10(6), 1150.
Source: NC State University Libraries
Added: August 6, 2018
1991 journal article
UTERINE EFFECTS, EPIGENETICS, AND POSTNATAL SKELETAL DEVELOPMENT IN THE MOUSE
EVOLUTION, 45(4), 891–909.
author keywords: BONE; EMBRYO TRANSFER; EPIGENETIC; MATERNAL EFFECTS; MATERNAL-FETAL INTERACTIONS; MOUSE; QUANTITATIVE GENETICS; SKELETAL DEVELOPMENT; UTERINE EFFECTS
Source: Web Of Science
Added: August 6, 2018
1989 journal article
A QUANTITATIVE-GENETICS PERSPECTIVE ON MAMMALIAN DEVELOPMENT
AMERICAN NATURALIST, 134(3), 486–512.
Source: Web Of Science
Added: August 6, 2018
