2009 journal article

Photoinactivation of Sindbis Virus Infectivity Without Inhibition of Membrane Fusion


By: W. Thongthai n & K. Weninger n

MeSH headings : Animals; Cells, Cultured; Cricetinae; Electrophoresis, Polyacrylamide Gel; Liposomes; Membrane Fusion; Sindbis Virus / pathogenicity; Sindbis Virus / radiation effects; Virulence / radiation effects
TL;DR: It is shown that photobleaching of Sindbis virus labeled with the membrane localized dye, R18 (octadecyl rhodamine B) causes a dramatic loss of infectivity without observable changes in low‐pH triggered membrane fusion to liposomes, and electrophoretic gel analysis suggests no cross‐linking of viral fusion proteins following photobreaching of dye‐labeled Sindbis. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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