Works (202)

Updated: April 4th, 2024 15:56

2023 article

Effects of Prebiotic Galactooligosaccharide (GOS) on Hindgut Microbial Composition of Pigs During the Peri-Weaning Period

Boston, T. E., Wang, F., Xi, L., Kim, S. W., Fellner, V., Scott, M. F., … Odle, J. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 187–188.

By: T. Boston n, F. Wang n, L. Xi, S. Kim n, V. Fellner n, M. Scott, A. Ziegler n, L. Van Landeghem n, A. Blikslager n, J. Odle n

author keywords: microbiome; prebiotics; weaning
Sources: Web Of Science, ORCID
Added: December 18, 2023

2023 article

Effects of Prebiotic Galactooligosaccharide (Gos) on Piglet Growth and Jejunal Morphology During the Peri-Weaning Period

Boston, T. E., Wang, F., Xi, L., Kim, S. W., Fellner, V., Scott, M. F., … Odle, J. (2023, October 28). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 276–277.

By: T. Boston n, F. Wang n, L. Xi, S. Kim n, V. Fellner n, M. Scott, A. Ziegler n, L. Van Landeghem n, A. Blikslager n, J. Odle n

author keywords: intestinal villi; galactooligosaccharides; prebiotics; weaning
Sources: Web Of Science, ORCID
Added: December 18, 2023

2023 journal article

Effects of medium chain triglycerides on hepatic fatty acid oxidation in clofibrate-fed newborn piglets

ANIMAL NUTRITION, 12, 334–344.

By: J. Zhao n, B. Pike n, J. Huang n, Z. Feng n, J. Odle n & . Lin n

author keywords: PPAR a; Clofibrate; Newborn piglets; Medium chain triglyceride (MCT); Hepatic fatty acid oxidation
TL;DR: It is suggested that dietary supplementation of anaplerotic and ketogenic FA could impact FA oxidation and modify the metabolism of acetyl-CoA via alteration of TCA cycle activity, but the modification has no significant impact on the hepatic FA oxidative capacity induced by PPARα. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: February 20, 2023

2023 article

Exploring the Prebiotic Activities of Proanthocyanidins on a Platform Using the Three-Dimensionally (3D)-Cultured Organoids

Xi, L., Wang, F., Cagle, D., Zhu, Y., Odle, J., & Xie, D. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 355–356.

By: L. Xi n, F. Wang n, D. Cagle n, Y. Zhu n, J. Odle n & D. Xie n

author keywords: antibiotics; Interleukins; organoids
TL;DR: It is concluded that epigallocatechin gallate is a potential PA monomer with all prebiotic characteristics and its applicable values in feedstuff and food supply should be studied in vivo studies in domestic (food) animals with and without antigen challenges. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: December 11, 2023

2023 journal article

Insect Peptide CopA3 Mitigates the Effects of Heat Stress on Porcine Muscle Satellite Cells

ANIMALS, 13(20).

author keywords: porcine satellite cell; CopA3; cell viability; heat shock protein; heat stress
TL;DR: It is demonstrated that 9-mer disulfide dimer peptide (CopA3) supplementation stabilizes porcine muscle satellite cell proliferation and heat shock protein (HSP) expression at different temperatures, thereby enhancing the heat-stress-tolerance capacity of PMSCs. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: November 20, 2023

2023 journal article

Intestinal Carnitine Status and Fatty Acid Oxidation in Response to Clofibrate and Medium-Chain Triglyceride Supplementation in Newborn Pigs

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(7).

By: B. Pike n, J. Zhao n, J. Hicks n, F. Wang n, R. Hagen n, H. Liu n, J. Odle n, . Lin n

author keywords: carnitine; fatty acid oxidation; intestine; medium-chain fatty acid; newborn pigs
MeSH headings : Animals; Swine; Clofibrate / pharmacology; Animals, Newborn; Carnitine / pharmacology; Carnitine / metabolism; Liver / metabolism; Palmitic Acid / pharmacology; Triglycerides / metabolism; Intestines; Dietary Supplements; Fatty Acids / metabolism; Oxidation-Reduction
TL;DR: It is suggested that dietary clofibrate improved carnitine status and increased fatty acid oxidation in neonates, and Propionyl-CoA, generated from TC5 and TMPA, could stimulate the increased fatty acids oxidation rate induced by cl ofibrate as anaplerotic carbon sources. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: March 25, 2023

2023 journal article

Manganese alleviates heat stress of primary cultured chick embryonic myocardial cells via enhancing manganese superoxide dismutase expression and attenuating heat shock response

JOURNAL OF THERMAL BIOLOGY, 112.

author keywords: Heat stress; Manganese; Manganese superoxide dismutase; Heat shock response; Chick myocardial cell
MeSH headings : Animals; Chickens / physiology; Heat-Shock Response; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; Manganese / pharmacology; Myocytes, Cardiac / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Chick Embryo
TL;DR: Results from the present study indicate that supplemental Mn, especially oMn, could enhance the MnSOD expression and attenuate heat shock response to protect against heat challenge in primary cultured chick embryonic myocardial cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: February 6, 2023

2023 journal article

MicroRNA and mRNA sequencing analyses reveal key hepatic metabolic and signaling pathways responsive to maternal undernutrition in full-term fetal pigs

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 116.

By: F. Wang n, C. Man n, X. Wang n, J. Odle n, C. Maltecca n & . Lin n

author keywords: Maternal undernutrition; RNA sequencing; mRNA-miRNA correlation analysis; Ingenuity Pathways Analysis (IPA); Oxidative phosphorylation
MeSH headings : Pregnancy; Female; Animals; Swine; RNA, Messenger / metabolism; Fetus / metabolism; Liver / metabolism; Signal Transduction; Malnutrition / metabolism
TL;DR: The correlation analyses showed that metabolic and signaling pathways such as oxidative phosphorylation, death receptor signaling, neuroinflammation signaling pathway, and estrogen receptor signaling pathways were significantly modified, and the gene modifications in these pathways were associated with the miRNA changes induced by the maternal undernutrition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: March 4, 2023

2022 journal article

Effect of in ovo manganese injection on the embryonic development, antioxidation, hatchability, and performances of offspring broilers under normal and high temperatures.

Poultry Science.

MeSH headings : Animals; Antioxidants / metabolism; Chickens / physiology; Embryonic Development; Manganese; Sulfates / pharmacology; Temperature
Source: ORCID
Added: April 1, 2023

2022 journal article

Gruel Creep Feeding Accelerates Growth and Alters Intestinal Health of Young Pigs

ANIMALS, 12(18).

By: T. Boston n, F. Wang n, . Lin n, S. Leonard n, S. Kim n, D. McKilligan, V. Fellner n, J. Odle n

Contributors: T. Boston n, F. Wang n, . Lin n, S. Leonard n, S. Kim n, D. McKilligan, V. Fellner n, J. Odle n

author keywords: creep feeding; intestinal health; piglet growth; weaning
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science
Added: September 15, 2022

2022 journal article

Reproductive Performance, Early Embryo Survival, Fetal Characteristics, and Tissue Fatty Acid Profiles of Sows Fed Linoleic or alpha-Linolenic Acid

Journal of Animal Science, 100, 55.

By: G. Shipman, L. Xi & E. van Heugten

Event: 2022 ASAS Midwest Section Meeting on November 18, 2022

Source: NC State University Libraries
Added: November 23, 2022

2021 journal article

Gut microbiome contributions to altered metabolism in a pig model of undernutrition

Proceedings of the National Academy of Sciences, 118(21), e2024446118.

By: H. Chang*, N. McNulty*, M. Hibberd*, D. O’Donnell*, J. Cheng*, V. Lombard*, B. Henrissat*, O. Ilkayeva* ...

author keywords: gut microbiome; malnutrition; carbohydrate-active enzymes; metabolic regulation; feature selection/information theory
MeSH headings : Algorithms; Animals; Body Weight; Butyrates / metabolism; Diet / methods; Diet Therapy / methods; Disease Models, Animal; Feces / microbiology; Gastrointestinal Microbiome / physiology; Germ-Free Life; Lipid Metabolism / physiology; Liver / metabolism; Male; Malnutrition / metabolism; Malnutrition / physiopathology; Mice; Mice, Inbred C57BL; Phosphoric Monoester Hydrolases / metabolism; Starch / metabolism; Sucrose / metabolism; Swine; Taurocholic Acid / metabolism; alpha-Glucosidases / metabolism
TL;DR: Using an intergenerational pig model of diet restriction (DR) that reduces weight gain, a feature-selection algorithm is developed to identify representative characteristics distinguishing DR fecal microbiomes from those of full-fed (FF) pigs as both groups consumed a common sequence of diets during their growth cycle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: June 21, 2021

2021 journal article

Maternal Supplementation of Clofibrate Stimulates Intestinal Fatty Acid Oxidation in Newborn Suckling Piglets

Current Developments in Nutrition, 5(Supplement_2), 542–542.

By: B. Pike n, J. Hicks n, J. Zhao n, H. Liu, J. Odle n & L. Xi n

TL;DR: Maternal dietary supplementation of clofibrate increases intestinal fatty acid oxidation in suckling offspring, but the increase is attenuated after one week, and the availability of carnitine could be a key element to maintain a high rate of intestinal fatty acids oxidation during the neonatal period. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2022

2021 journal article

MicroRNA and mRNA Sequencing Analyses Reveal Key Hepatic Metabolic Pathways Responsive to Maternal Malnutrition in Full-Term Fetal Pigs

Current Developments in Nutrition, 5(Supplement_2), 829–829.

By: F. Wang n, C. Maltecca n, X. Wang n, J. Odle n & L. Xi

TL;DR: The results provide the framework for further understanding of negative impact of maternal malnutrition on hepatic metabolic pathways via miRNA-RNA interactions in full-term fetal pigs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: February 9, 2022

2021 journal article

Modulation of intestinal stem cell homeostasis by nutrients: a novel therapeutic option for intestinal diseases

Nutrition Research Reviews, 6, 1–9.

author keywords: Intestinal stem cells; Self-renewal; Differentiation; Dietary patterns; Intestinal diseases
MeSH headings : Diet, High-Fat; Homeostasis; Humans; Intestinal Diseases / therapy; Nutrients; Stem Cells / metabolism
TL;DR: The current understanding of how intestinal stem cells contribute to intestinal epithelial homeostasis and diseases is summarized and the effects of diet and nutrient-sensing pathways on intestinal stem cell self-renewal and differentiation are discussed, as well as their potential application in the prevention and treatment of intestinal diseases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: February 9, 2022

2021 journal article

Zinc alleviates the heat stress of primary cultured hepatocytes of broiler embryos via enhancing the antioxidant ability and attenuating the heat shock responses

Animal Nutrition, 7(3), 621–630.

author keywords: Broiler hepatocyte; Zinc; Heat stress; Antioxidant ability; Heat shock response
TL;DR: It was concluded that Zn (especially oZn) could alleviate heat stress of broiler hepatocytes via enhancing their antioxidant ability and attenuating heat shock responses. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: October 12, 2021

2020 journal article

Effects of Dietary Anaplerotic and Ketogenic Energy Sources on Renal Fatty Acid Oxidation Induced by Clofibrate in Suckling Neonatal Pigs

International Journal of Molecular Sciences, 21(3), 726.

author keywords: Renal fatty acid oxidation; anaplerotic and ketogenic energy; PPAR alpha activation
MeSH headings : Animals; Animals, Newborn; Carnitine / pharmacology; Clofibrate / pharmacology; Diet; Fatty Acids / metabolism; Ketone Bodies / metabolism; Kidney / drug effects; Kidney / metabolism; Lipid Metabolism / drug effects; Lipid Metabolism / physiology; Milk / metabolism; Oxidation-Reduction / drug effects; PPAR alpha / metabolism; Palmitic Acid / metabolism; Swine
TL;DR: Modification of anaplerosis or ketogenesis via dietary substrates had no influence on in vitro renal palmitic acid oxidation induced by PPARα activation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, ORCID
Added: February 4, 2020

2020 journal article

Long-term exposure to TET increases body weight of juvenile zebrafish as indicated in host metabolism and gut microbiome

Environment International, 139, 105705.

By: T. Keerthisinghe*, F. Wang n, M. Wang*, Q. Yang*, J. Li*, J. Yang*, L. Xi n, W. Dong*, M. Fang*

author keywords: Zebrafish; Tetracycline; Metabolism; Lipid accumulation; Gut microbiome
MeSH headings : Animals; Anti-Bacterial Agents; Body Weight; Fatty Acid-Binding Proteins; Gastrointestinal Microbiome; Lipid Metabolism; Water Pollutants, Chemical / toxicity; Zebrafish; Zebrafish Proteins
TL;DR: This is the first study showing that TET exposure can increase the body weight in juvenile zebrafish and the study on the ecotoxicity of antibiotic occurrences in the aquatic system can be further warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: October 19, 2020

2020 journal article

Maternal Feeding of a Synthetic PPARα Agonist Alters Renal Development of Fatty Acid Metabolism in the Neonatal Piglet

Current Developments in Nutrition, 4(Supplement_2), 702–702.

By: L. Xi n, B. Pike n, J. Zhao n & J. Odle n

TL;DR: The stimulatory effect of maternal clofibrate on renal fatty acid metabolism in offspring is associated with the postnatal age, being greater at d1 and d7 than d14 and d19, but decreased 14C-ESP measured in d7 pigs. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 3, 2020

2020 journal article

Maternal Supplementation of Clofibrate Stimulates Hepatic Fatty Acid Oxidation in Newborn Suckling Piglets

Current Developments in Nutrition, 4(Supplement_2), 703–703.

By: J. Zhao n, B. Pike n, J. Odle n & L. Xi n

Sources: Crossref, ORCID
Added: December 3, 2020

2020 journal article

Ontogeny of carnitine biosynthesis inSus scrofa domesticus, inferred from γ-butyrobetaine hydroxylase (dioxygenase) activity and substrate inhibition

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 319(1), R43–R49.

By: X. Lin n, P. Lyvers Peffer n, J. Woodworth* & J. Odle n

Contributors: X. Lin n, P. Lyvers Peffer n, J. Woodworth* & J. Odle n

author keywords: gamma-butyrobetaine hydroxylase; carnitine synthesis; development; kinetics; substrate inhibition
MeSH headings : Aging / metabolism; Animals; Animals, Newborn; Body Weight; Carnitine / biosynthesis; Enzyme Inhibitors / pharmacology; Kidney / enzymology; Kidney / growth & development; Kidney / metabolism; Kinetics; Liver / enzymology; Liver / growth & development; Liver / metabolism; Organ Size; Sus scrofa; Swine; gamma-Butyrobetaine Dioxygenase / antagonists & inhibitors; gamma-Butyrobetaine Dioxygenase / metabolism
TL;DR: Age and substrate affect γ-BBH specific activity and Km in liver and kidney and while the predominant organ for carnitine synthesis is likely the kidney at birth, the liver appears to predominate after the pig exceeds 7 day of age. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID
Added: June 23, 2020

2020 journal article

Research Note: Responses of growth performance, immune traits, and small intestinal morphology to dietary supplementation of chromium propionate in heat-stressed broilers

Poultry Science, 99(10), 5070–5073.

author keywords: chromium; heat-stressed broiler; growth performance; immunity; intestinal morphology
MeSH headings : Animal Feed / analysis; Animals; Chickens / growth & development; Chickens / immunology; Diet / veterinary; Dietary Supplements; Heat-Shock Response / drug effects; Immunity / drug effects; Intestine, Small / drug effects; Male; Propionates / pharmacology; Random Allocation
TL;DR: The results indicate that CrPro supplementation could modify the intestinal morphology of the duodenum and influence serum IgG and IgM concentrations in heat-stressed broiler chickens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: November 9, 2020

2020 journal article

Supplemental methionine and stocking density affect antioxidant status, fatty acid profiles, and growth performance of broiler chickens

Journal of Animal Science, 98(4).

By: A. Magnuson*, G. Liu*, T. Sun*, S. Tolba*, L. Xi*, R. Whelan*, X. Lei

author keywords: antioxidant; broiler; methionine; oxidative stress; stocking density
MeSH headings : Animal Feed / analysis; Animals; Antioxidants / metabolism; Body Weight / drug effects; Chickens / growth & development; Chickens / physiology; Diet / veterinary; Dietary Supplements / analysis; Fatty Acids / analysis; Glutathione / analysis; Glutathione Peroxidase / metabolism; Liver / metabolism; Male; Malondialdehyde / analysis; Methionine / pharmacology; Oxidation-Reduction; Superoxide Dismutase / metabolism
TL;DR: The 30% extra supplemental DL-methionine supplementation was able to partially mitigate adverse effects caused by the higher stocking density and to improve redox status of the broilers. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: May 26, 2020

2019 journal article

125 Supplementing extra dietary DL-methionine mitigates effects of higher stocking density on growth performance, meat quality, and health status of broiler chicks

Journal of Animal Science, 97(Supplement_3), 111–111.

TL;DR: The high stocking density affected growth performance, meat quality, and health status of broilers, and Supplementing 30% extra dietary methionine seemed to mitigate some of those effects. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2019 journal article

Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages

Journal of Animal Science and Biotechnology, 10(1).

Contributors: K. Walter n, X. Lin n, S. Jacobi*, T. Käser n, D. Esposito n & J. Odle n

author keywords: Arachidonic acid; Cyclooxygenase; Eicosanoid; Eicosapentaenoic acid; Inflammation; Lipid mediator class switch; LPS; Lipoxin; Porcine alveolar macrophage
TL;DR: It is inferred that enriching diets with arachidonic acid may be an effective means to enhance a stronger innate immunologic response to respiratory challenges in neonatal pigs, but further work is needed to examine long-term safety, clinical efficacy and economic viability. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: April 20, 2020

2019 journal article

EPA and DHA Inhibit Myogenesis and Downregulate the Expression of Muscle-related Genes in C2C12 Myoblasts

Genes, 10(1), 64.

author keywords: C2C12; proliferation; differentiation; EPA; DHA
MeSH headings : Animals; Cell Differentiation; Cell Line; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / metabolism; MAP Kinase Signaling System; Mice; Muscle Development; Myoblasts / cytology; Myoblasts / drug effects; Myoblasts / metabolism; Myoglobin / genetics; Myoglobin / metabolism; Myosin Heavy Chains / genetics; Myosin Heavy Chains / metabolism; Myosin Light Chains / genetics; Myosin Light Chains / metabolism; Troponin / genetics; Troponin / metabolism
TL;DR: It is suggested that EPA and DHA exerted an inhibitory effect on myoblast proliferation and differentiation and downregulated muscle-related genes expression. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: March 18, 2019

2019 journal article

EPA and DHA attenuate deoxynivalenol‐induced intestinal porcine epithelial cell injury and protect barrier function integrity by inhibiting necroptosis signaling pathway

The FASEB Journal, 34(2), 2483–2496.

author keywords: barrier function; cell injury; deoxynivalenol; necroptosis signaling pathway; n-3 PUFA
MeSH headings : Animals; Docosahexaenoic Acids / pharmacology; Eicosapentaenoic Acid / pharmacology; Epithelial Cells / metabolism; Epithelial Cells / pathology; Intestinal Mucosa / injuries; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Necroptosis / drug effects; Signal Transduction / drug effects; Swine; Trichothecenes / toxicity
TL;DR: It is suggested that EPA and DHA prevent DON‐induced intestinal cell injury and enhance barrier function, which is associated with inhibition of the necroptosis signaling pathway. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: January 6, 2020

2019 journal article

Maternal manganese activates anti-apoptotic-related gene expressions via miR-1551 and miR-34c in embryonic hearts from maternal heat stress (Gallus gallus)

Journal of Thermal Biology, 84, 190–199.

author keywords: Maternal heat stress; Manganese; MicroRNA expression; Anti-apoptotic gene expression; Offspring chick embryo; Heart
MeSH headings : Animals; Apoptosis / drug effects; Avian Proteins / genetics; Bird Diseases; Chick Embryo; Chickens; Female; Gene Expression Regulation, Developmental / drug effects; Heart / drug effects; Heart / embryology; Heat Stress Disorders / veterinary; Male; Manganese / pharmacology; MicroRNAs; NF-kappa B / genetics; Proto-Oncogene Proteins c-bcl-2 / genetics
TL;DR: Under maternal heat stress, maternal supplemental 120 mg Mn/kg activated target BCL2 expression and NIK-dependent NF-κB pathway via mediatingMiR-1551 and miR-34c expressions in hearts of offspring embryos rather than broilers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: October 7, 2019

2019 journal article

PSV-11 Effects of plasma protein on growth performance and intestinal health of weaned pigs

Journal of Animal Science, 97(Supplement_2), 197–197.

By: G. Martinez Padilla n, Y. Silva-Guillen n, K. Moran n, X. Lin n, J. Odle n & E. Heugten

author keywords: plasma protein; performance; cytokines
TL;DR: It is suggested that PP was not effective in improving overall growth performance and had minimal effects on intestinal health of weanling pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 12, 2019

2018 journal article

Effect of In Ovo Zinc Injection on the Embryonic Development and Epigenetics-Related Indices of Zinc-Deprived Broiler Breeder Eggs

Biological Trace Element Research, 185(2), 456–464.

author keywords: In ovo zinc injection; Chick embryo; Metallothionein; Epigenetics
MeSH headings : Animals; Antioxidants / metabolism; Chickens; Eggs / analysis; Embryonic Development / drug effects; Epigenesis, Genetic / drug effects; Epigenesis, Genetic / genetics; Female; Random Allocation; Zinc / administration & dosage; Zinc / pharmacology
TL;DR: It is demonstrated that in ovo Zn injection improved the embryonic development, and the organic Zn was more effective than inorganic Zn in enhancing DNA methylation and H3K9 acetylation in the liver MT4 promoter, but the precise mechanisms require further investigations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: October 19, 2018

2018 journal article

Effect of in ovo zinc injection on the embryonic development, tissue zinc contents, antioxidation, and related gene expressions of broiler breeder eggs

Journal of Integrative Agriculture, 17(3), 648–656.

By: X. Sun*, X. Liao*, L. Lu*, L. Zhang*, Q. Ma*, L. Xi, X. Luo*

author keywords: in ovo injection; zinc; embryonic development; gene expression; broiler breeder egg
TL;DR: The findings suggest that the E9 is the optimal embryonic age for early in ovo zinc (Zn) injection, and injections of 50, 150 and 200 μg Zn/egg up-regulated in the embryonic mortality and hatchability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: August 28, 2020

2018 journal article

Effects of environmental temperature and dietary zinc on egg production performance, egg quality and antioxidant status and expression of heat-shock proteins in tissues of broiler breeders

British Journal of Nutrition, 120(1), 3–12.

author keywords: Broiler breeders; Zinc; Heat stress; Antioxidant status; Heat-shock proteins
MeSH headings : Animal Feed; Animal Nutrition Sciences; Animals; Antioxidants / metabolism; Chickens; Diet / veterinary; Eggs; Female; HSP70 Heat-Shock Proteins / metabolism; Heat-Shock Proteins / metabolism; Liver / drug effects; Malondialdehyde / metabolism; Metallothionein / metabolism; Pancreas / drug effects; RNA, Messenger / metabolism; Random Allocation; Superoxide Dismutase-1 / metabolism; Temperature; Zinc / administration & dosage; Zinc Sulfate / administration & dosage
TL;DR: The results from this study indicated that HT impaired egg production performance and eggshell quality possibly because of the disturbed redox balance and HSP homoeostasis, whereas the oZn is more available than the iZn for pancreatic Zn of heat-stressed laying broiler breeders. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2018 journal article

Pharmacologic activation of peroxisome proliferator-activating receptor-α accelerates hepatic fatty acid oxidation in neonatal pigs

Oncotarget, 9(35), 23900–23914.

TL;DR: Although the induction patterns of CPTI, MCD, ACO, KetoACoA, and ACCβ are different during the early postnatal period, 4 days of exposure to clofibrate were sufficient to robustly accelerate fatty acid oxidation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: December 3, 2020

2017 journal article

876 Effects of sporoderm-broken spores of Ganoderma lucidum on growth performance, antioxidant function, and immune response of broiler chickens

Journal of Animal Science, 95(suppl_4), 375–375.

author keywords: antioxidant capability; oxidative stress; spore of Ganoderma lucidum
Sources: Crossref, ORCID
Added: February 20, 2022

2017 journal article

Activation of PPARα by Oral Clofibrate Increases Renal Fatty Acid Oxidation in Developing Pigs

International Journal of Molecular Sciences, 18(12), 2663.

By: Y. He n, I. Khan n, X. Bai n, J. Odle n & L. Xi n

Contributors: Y. He n, I. Khan n, X. Bai n, J. Odle n & L. Xi n

author keywords: peroxisome proliferator-activated receptor alpha (PPAR alpha); clofibrate; fatty acid beta-oxidation; pigs
MeSH headings : 3-Hydroxybutyric Acid / biosynthesis; Animals; Clofibrate / administration & dosage; Fatty Acids / biosynthesis; Fatty Acids / genetics; Hydroxymethylglutaryl-CoA Synthase / biosynthesis; Kidney / drug effects; Kidney / metabolism; Lipid Metabolism / genetics; Mitochondria / genetics; Mitochondria / metabolism; Oxidation-Reduction; PPAR alpha / genetics; Peroxisomes / genetics; Peroxisomes / metabolism; Swine
TL;DR: It is found that PPARα activation stimulates renal fatty acid oxidation but not ketogenesis, and the mRNA abundance and enzyme activity of carnitine palmitoyltransferase I in mitochondria were increased. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Dietary Prebiotics and Arachidonic Acid (ARA) Modulate Intestinal Injury and Microbial Taxa Following Acute Dextran Sodium Sulfate Induced Colitis in Formula‐Fed Piglets

The FASEB Journal, 31(S1).

By: S. Jacobi*, L. Xi n, C. Maltecca n, L. Borst n, A. Smith n & J. Odle n

TL;DR: In conclusion supplementation of formula with prebiotics significantly shifts microbial taxa on d22, modulates intestinal pH, and laxation, and main effects of diet and DSS on epithelial damage, lamina propria inflammation, crypt abscess, crypt dropout, and overall colitis score are shown. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2017 journal article

Dietary long-chain PUFAs enrich porcine alveolar macrophages and alter Prostaglandin E-2 Production Following LPS Challenge

FASEB Journal, 31.

By: K. Walter, L. Xi, S. Jacobi, D. Esposito & J. Odle

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Dietary prebiotics and arachidonic acid alter intestinal phospholipid composition and time-dependently change fecal microbiome in formula-fed piglets

FASEB Journal, 31.

By: M. Thorpe, L. Xi, C. Maltecca, K. Walters, A. Smith, J. Odle, S. Jacobi

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Effect of Medium Chain Triglycerides on TCA and Ketogenic Capacity of Proximal Intestinal Fatty Acid Oxidation in Clofibrate Feed Newborn Pigs

The FASEB Journal, 31(S1).

By: B. Pike n, J. Zhao n, J. Hicks n, Y. Zhang n, A. Smith n, H. Liu n, J. Odle n, L. Xi n

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, ORCID
Added: February 20, 2022

2017 journal article

Effects of Dietary Anaplerotic Carbon Sources and Ketogenic Fatty Acids on Hepatic Fatty Acid Oxidation in Neonatal Pigs

The FASEB Journal, 31(S1).

By: J. Zhao n, B. Pike n, Y. Zhang n, S. Sabin n, A. Smith n, Y. Zhu n, J. Odle n, L. Xi n

Sources: Crossref, ORCID
Added: February 20, 2022

2017 journal article

Effects of dietary supplementation of resveratrol on performance, egg quality, yolk cholesterol and antioxidant enzyme activity of laying hens

British Poultry Science, 58(5), 544–549.

By: Z. Feng*, J. Gong*, G. Zhao*, X. Lin n, Y. Liu & K. Ma

author keywords: Egg quality; egg yolk cholesterol; laying performance; resveratrol; serum oxidative status
MeSH headings : Animal Feed / analysis; Animals; Antioxidants / metabolism; Chickens / physiology; Cholesterol / metabolism; Diet / veterinary; Dietary Supplements / analysis; Egg Yolk / chemistry; Female; Ovum / physiology; Resveratrol; Stilbenes / administration & dosage; Stilbenes / metabolism
TL;DR: It is concluded that resveratrol supplementation has a positive effect on performance, lipid-related traits and antioxidant activity of laying hens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

Impact of maternal heat stress in conjunction with dietary zinc supplementation on hatchability, embryonic development, and growth performance in offspring broilers

Poultry Science, 96(7), 2351–2359.

By: Y. Zhu*, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: chick embryo; growth performance; maternal heat stress; offspring; zinc
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena / drug effects; Animals; Chick Embryo; Chickens / growth & development; Chickens / physiology; Diet / veterinary; Dietary Supplements / analysis; Embryonic Development / drug effects; Female; Hot Temperature / adverse effects; Male; Random Allocation; Reproduction / drug effects; Zinc / administration & dosage; Zinc / metabolism
TL;DR: It is indicated that maternal heat stress impairs hatching performance, embryonic development, and progeny growth performance, inducing metabolic changes, while supplementation of Zn in maternal diets regardless of ZN sources improved hatch chick quality and survivability of offspring and alleviated the negative effect of maternalHeat stress on growth performance of offspring during the starter period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

Manganese enhances the expression of the manganese superoxide dismutase in cultured primary chick embryonic myocardial cells

Journal of Integrative Agriculture, 16(9), 2038–2046.

By: S. Qin*, X. Liao*, L. Lu*, L. Zhang*, L. Xi, Y. Guo*, X. Luo*

author keywords: manganese; MnSOD; expressions; cultured primary myocardial cells; chick embryos
TL;DR: The results showed that MnS OD activity and mRNA expression level were induced by Mn and increased with incubation time, which supported the hypothesis that Mn would enhance the expression of the MnSOD gene, and thus might protect myocardial cells from oxidative stress during the chick embryonic development. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

Maternal dietary manganese protects chick embryos against maternal heat stress via epigenetic-activated antioxidant and anti-apoptotic abilities

Oncotarget, 8(52), 89665–89680.

By: Y. Zhu*, L. Lu*, X. Liao*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n ...

Contributors: Y. Zhu*, L. Lu*, X. Liao*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: epigenetics; maternal environmental hyperthermia; manganese superoxide dismutase; apoptosis; chick embryo
TL;DR: It is suggested that maternal dietary manganese addition could protect the chick embryonic development against maternal heat stress via enhancing epigenetic-activated antioxidant and anti-apoptotic abilities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures

Oncotarget, 8(12), 19814–19824.

By: Y. Zhu*, X. Liao*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n ...

Contributors: Y. Zhu*, X. Liao*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: epigenetics; maternal hyperthermia; zinc; metallothionein; chick embryo
MeSH headings : Acetylation / drug effects; Animal Nutritional Physiological Phenomena; Animals; Antioxidants / metabolism; Avian Proteins / genetics; Avian Proteins / metabolism; Blotting, Western; Chick Embryo; Chickens; DNA Methylation / drug effects; Dietary Supplements; Epigenesis, Genetic / drug effects; Female; Gene Expression Regulation, Developmental / drug effects; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Histones / metabolism; Hot Temperature; Liver / drug effects; Liver / embryology; Liver / metabolism; Lysine / metabolism; Metallothionein / genetics; Metallothionein / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Zinc / administration & dosage; Zinc / pharmacology
TL;DR: It is demonstrated that maternal dietary zinc addition as an epigenetic modifier could protect the offspring embryonic development against maternal heat stress via enhancing the epigenetic-activated antioxidant ability. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts

Current Developments in Nutrition, 2(3).

Contributors: H. Lima n, X. Lin n, S. Jacobi n, C. Man n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Gonzalez n, J. Odle n

author keywords: choline; B-vitamins; epigenetics; intrauterine growth restriction; nutrient restriction; low birth weight
TL;DR: Despite the mobilization of maternal stores, malnourished litters displayed reduced brain development that was fully mitigated by micronutrient supplementation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2016 journal article

Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge

Innate Immunity, 22(8), 577–587.

By: S. Chen*, Y. Liu*, X. Wang*, H. Wang*, S. Li*, H. Shi*, H. Zhu*, J. Zhang ...

Contributors: S. Chen*, Y. Liu*, X. Wang*, H. Wang*, S. Li*, H. Shi*, H. Zhu*, J. Zhang ...

author keywords: Asparagine; weanling piglets; intestine; lipopolysaccharide; inflammatory response
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Apoptosis / drug effects; Asparagine / pharmacology; Caspase 3 / metabolism; Cell Proliferation / drug effects; Cells, Cultured; Cytokines / metabolism; Enterocytes / drug effects; Enterocytes / physiology; Enzyme Inhibitors / pharmacology; Inflammation / drug therapy; Inflammation Mediators / metabolism; Intestinal Mucosa / immunology; Intestinal Mucosa / pathology; Lipopolysaccharides / immunology; MAP Kinase Signaling System / drug effects; Ornithine Decarboxylase / metabolism; Oxygenases / metabolism; Phosphorylation / drug effects; Swine; Toll-Like Receptor 4 / metabolism; Weaning; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: The results suggest that Asn improves intestinal integrity during an inflammatory insult, which appears to be related to the decrease of intestinal pro-inflammatory cytokine and of enterocyte apoptosis (via p38 and ERK1/2). (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2016 journal article

Asparagine reduces the mRNA expression of muscle atrophy markers via regulating protein kinase B (Akt), AMP-activated protein kinase α, toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling in weaning piglets after lipopolysaccharide challenge

British Journal of Nutrition, 116(7), 1188–1198.

By: X. Wang*, Y. Liu*, S. Wang*, D. Pi*, W. Leng*, H. Zhu*, J. Zhang*, H. Shi* ...

Contributors: X. Wang*, Y. Liu*, S. Wang*, D. Pi*, W. Leng*, H. Zhu*, J. Zhang*, H. Shi* ...

author keywords: Asparagine; Lipopolysaccharides; Muscle atrophy; Pro-inflammatory cytokines
MeSH headings : AMP-Activated Protein Kinases / antagonists & inhibitors; AMP-Activated Protein Kinases / metabolism; Animals; Asparagine / pharmacology; Enzyme Activation / drug effects; F-Box Proteins / analysis; F-Box Proteins / genetics; Forkhead Box Protein O1 / antagonists & inhibitors; Gene Expression / drug effects; Lipopolysaccharides / pharmacology; Muscle Proteins / metabolism; Muscle, Skeletal / chemistry; Muscular Atrophy / chemically induced; Muscular Atrophy / genetics; Nod Signaling Adaptor Proteins / antagonists & inhibitors; Phosphorylation / drug effects; Polycomb Repressive Complex 1 / analysis; Polycomb Repressive Complex 1 / genetics; Proto-Oncogene Proteins c-akt / metabolism; RNA, Messenger / analysis; Signal Transduction / drug effects; Sus scrofa; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Weaning
TL;DR: The beneficial effects of Asn on muscle atrophy may be associated with inhibiting muscle protein degradation via activating Akt and inactivating AMPKα and FOXO1; and decreasing the expression of muscle pro-inflammatory cytokines via inhibiting TLR4 and NOD signalling pathways by modulation of their negative regulators. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2016 journal article

Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures

British Journal of Nutrition, 116(11), 1851–1860.

Contributors: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: Broiler breeders; Manganese; Heat stress; Antioxidant status; Heat shock proteins/factors
MeSH headings : Animals; Avian Proteins / genetics; Avian Proteins / metabolism; Biomarkers / metabolism; Chelating Agents / administration & dosage; Chickens / growth & development; Chickens / physiology; China; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Diet / veterinary; Female; Gene Expression Regulation, Developmental; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; Heart Ventricles / enzymology; Heart Ventricles / growth & development; Heart Ventricles / metabolism; Heat Shock Transcription Factors; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Heat-Shock Response; Intestinal Absorption; Liver / enzymology; Liver / growth & development; Liver / metabolism; Manganese / administration & dosage; Manganese / metabolism; Manganese Compounds / administration & dosage; Muscle, Skeletal / enzymology; Muscle, Skeletal / growth & development; Muscle, Skeletal / metabolism; Oxidative Stress; RNA, Messenger / metabolism; Random Allocation; Sulfates / administration & dosage; Trans-Activators / genetics; Trans-Activators / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is indicated that high temperature decreases Mn retention and increases HSP70, HSF1 and HSF3 expressions in the tissues of laying broiler breeders and dietary supplementation with Mn in either source may enhance the heart’s antioxidant ability and inhibit the expression of HSP 70 in breast muscle. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2016 journal article

Effects of Supplemental Chromium Propionate on Serum Lipids, Carcass Traits, and Meat Quality of Heat-Stressed Broilers

Biological Trace Element Research, 176(2), 401–406.

author keywords: Chromium; Heat-stressed broilers; Carcass traits; Serum lipids; Meat quality
MeSH headings : Animals; Chickens; Cholesterol, LDL / blood; Dietary Supplements; Heat Stress Disorders / blood; Heat Stress Disorders / metabolism; Hot Temperature; Male; Meat / analysis; Meat / standards; Propionates / administration & dosage; Propionates / metabolism; Propionates / pharmacology; Triglycerides / blood
TL;DR: It is indicated that CrPro supplementation could be beneficial to serum lipids metabolism of heat-stressed broiler chickens by decreasing TG and LDLC contents, but had no impacts on meat quality and carcass traits of the heat-Stressed broilers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2016 conference paper

Effects of increasing krebs cycle capacity by providing anaplerotic carbon and ketogenic fatty acids on palmitic acid oxidation in kidney of neonatal piglets

Presented at the Annual NC State Summer Undergraduate Research Symposium, Raleigh, NC.

By: S. Sabin & L. Xi

Event: Annual NC State Summer Undergraduate Research Symposium at Raleigh, NC

Source: NC State University Libraries
Added: April 30, 2022

2016 journal article

Manganese elevates manganese superoxide dismutase protein level through protein kinase C and protein tyrosine kinase

BioMetals, 29(2), 265–274.

By: S. Li*, L. Lu*, X. Liao*, T. Gao*, F. Wang*, L. Zhang*, L. Xi, S. Liu*, X. Luo*

author keywords: Manganese; Manganese superoxide dismutase; Mitogen-activated protein kinases; Protein kinase C; Protein tyrosine kinase; Primary broiler myocardial cell
MeSH headings : Animals; Avian Proteins / metabolism; Cells, Cultured; Chickens; Enzyme Activation; Male; Manganese / pharmacology; Phosphorylation; Protein Biosynthesis; Protein Kinase C / metabolism; Protein Processing, Post-Translational; Protein-Tyrosine Kinases / metabolism; Superoxide Dismutase / metabolism
TL;DR: The results suggested that Mn- induced MnSOD mRNA and protein expressions be not related with NAC, and MAPK pathways might not involve in Mn-induced MnS OD mRNA expression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Acute Dextran Sodium Sulfate Dose‐Dependently Induces Colitis in Formula‐Fed Piglets

The FASEB Journal, 29(S1).

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: February 20, 2022

2015 journal article

Effects of Supplemental Chromium Source and Concentration on Growth Performance, Carcass Traits, and Meat Quality of Broilers Under Heat Stress Conditions

Biological Trace Element Research, 170(1), 216–223.

author keywords: Chromium; Growth performance; Carcass characteristics; Meat quality; Broilers; Heat stress
MeSH headings : Animals; Chickens / growth & development; Chromium / administration & dosage; Female; Heat-Shock Response; Poultry
TL;DR: Results from this study indicate that Cr supplementation, independent of its source, could promote growth and improve carcass traits and meat quality of broilers under heat stress conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2015 journal article

Effects of Supplemental Chromium Source and Concentration on Growth, Carcass Characteristics, and Serum Lipid Parameters of Broilers Reared Under Normal Conditions

Biological Trace Element Research, 169(2), 352–358.

author keywords: Broilers; Carcass characteristics; Chromium; Lipid parameters; Normal rearing conditions
MeSH headings : Abdominal Fat / drug effects; Abdominal Fat / growth & development; Animal Feed / analysis; Animals; Chickens / growth & development; Chickens / metabolism; Chlorides / analysis; Chlorides / pharmacology; Cholesterol / blood; Chromium / analysis; Chromium / pharmacology; Chromium Compounds / analysis; Chromium Compounds / pharmacology; Dietary Supplements; Liver / drug effects; Liver / growth & development; Muscle, Skeletal / drug effects; Muscle, Skeletal / growth & development; Picolinic Acids / analysis; Picolinic Acids / pharmacology; Propionates / analysis; Propionates / pharmacology
TL;DR: It is indicated that dietary supplementation of Cr has effects on carcass characteristics and serum lipid parameters of broilers under normal rearing conditions, while supplementation of organic Cr can improve carcasses characteristics and reduce the cholesterol content in serum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2015 conference paper

Effects of TCA cycle and ketogenic capacity on fatty acid oxidation induced by clofibrate in suckling neonatal pigs

Presented at the Project Director Meeting in conjunction with the 2015 JAM meeting, Salt Lake City, UT.

By: J. Zhao, B. Pike, S. Sabin, J. Odle & L. Xi

Event: Project Director Meeting in conjunction with the 2015 JAM meeting at Salt Lake City, UT

Source: NC State University Libraries
Added: April 30, 2022

2015 journal article

Effects of acute and chronic heat stress on plasma metabolites, hormones and oxidant status in restrictedly fed broiler breeders

Poultry Science, 94(7), 1635–1644.

author keywords: broiler breeder; heat stress; metabolite; hormone; oxidation
MeSH headings : Animals; Blood Chemical Analysis / veterinary; Chickens / physiology; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Heat-Shock Response; Hormones / blood; Oxidants / metabolism; Radioimmunoassay / veterinary; Random Allocation
TL;DR: Taking together, acute heat stress primarily resulted in disturbance of plasma metabolites, whereas chronic heat stress caused tissue damage reflected by increased plasma LDA, GOT, and CK. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2015 journal article

Effects of environmental temperature and dietary manganese on egg production performance, egg quality, and some plasma biochemical traits of broiler breeders

Journal of Animal Science, 93(7), 3431–3440.

By: Y. Zhu*, J. Xie, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: broiler breeders; high temperature; laying performance; manganese; plasma biochemical traits
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens / physiology; Diet / veterinary; Dietary Supplements; Eggs / standards; Female; Lipid Peroxidation; Malondialdehyde / metabolism; Manganese / pharmacology; Oviposition / drug effects; Plasma; Protein Carbonylation; Soybeans / chemistry; Temperature
TL;DR: The results from this study indicated that high temperature significantly impaired egg production performance and eggshell quality and induced lipid peroxidation and tissue damage whereas dietary supplementation of either organic or inorganic Mn improved eggshell strength and thermotolerance and reduced protein oxidation and that the organic Mn could alleviate the negative effect of high temperature on eggProduction performance of broiler breeders at the period of 32 to 45 wk of age. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2015 journal article

Effects of maternal dietary manganese and incubation temperature on hatchability, antioxidant status, and expression of heat shock proteins in chick embryos

Journal of Animal Science, 93(12), 5725–5734.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: antioxidant status; chick embryo; heat shock protein; incubation temperatures; manganese
MeSH headings : Animal Feed / analysis; Animal Feed / standards; Animals; Antioxidants / metabolism; Body Weight; Chick Embryo / metabolism; Chick Embryo / physiology; Chickens / physiology; Diet / veterinary; Dietary Supplements; Egg Yolk / chemistry; Female; Heat-Shock Proteins / metabolism; Hot Temperature / adverse effects; Liver / embryology; Liver / enzymology; Liver / metabolism; Malondialdehyde / analysis; Manganese / administration & dosage; Manganese / analysis; Manganese / pharmacology; Maternal Nutritional Physiological Phenomena / physiology; Myocardium / enzymology; Random Allocation; Superoxide Dismutase / analysis; Superoxide Dismutase / genetics
TL;DR: Maternal dietary supplementation of Mn could improve the hatchability as well as antioxidant ability to protect against heat challenge in embryos during incubation, and indicated that high incubation temperature induced self-protective responses of chick embryos with a modification of antioxidant status and a depression of HSP70 protein level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2015 journal article

Effects of pre-slaughter stressor and feeding preventative Chinese medicinal herbs on glycolysis and oxidative stability in pigs

Animal Science Journal, 87(8), 1028–1033.

By: X. Bai, X. Yan, L. Xie, X. Hu, X. Lin n, C. Wu, N. Zhou*, A. Wang, M. See n

Contributors: X. Bai, X. Yan, L. Xie, X. Hu, X. Lin n, C. Wu, N. Zhou*, A. Wang, M. See n

author keywords: Chinese medicinal herbs; glycogen; oxidative; pig; stress
MeSH headings : Abattoirs; Animal Feed; Animals; Antioxidants; Blood Glucose / metabolism; Diet / veterinary; Dietary Supplements; Female; Glycolysis / drug effects; Lactic Acid / blood; Lycium; Male; Oxidation-Reduction / drug effects; Oxidative Stress / physiology; Plants, Medicinal; Polygala; Soybeans; Stress, Physiological / physiology; Swine / metabolism; Swine / physiology; Zea mays
TL;DR: It is shown that pre-slaughter stress induces oxidative stress in pigs and dietary supplementation with 1% LB improves antioxidant capacity in stressed pigs before slaughtering. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2015 journal article

Maternal Undernutrition Affects Expression of Genes Associated with Ileal Development and Metabolism in Full‐term Offspring

The FASEB Journal, 29(S1).

By: C. Man n, Y. Fan n, H. Lima n, S. Jacobi n, S. Lui n, J. Odle n, L. Xi n

TL;DR: The results strongly suggest that nutrient restriction during pregnancy can affect the programming of fetal ileum development and metabolism via regulation of gene expression and that post‐transcriptional mechanisms might be involved in. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: February 20, 2022

2015 journal article

Protective Effects of Bacillus subtilis ANSB060 on Serum Biochemistry, Histopathological Changes and Antioxidant Enzyme Activities of Broilers Fed Moldy Peanut Meal Naturally Contaminated with Aflatoxins

Toxins, 7(8), 3330–3343.

MeSH headings : Aflatoxins / analysis; Aflatoxins / toxicity; Animal Feed / adverse effects; Animal Feed / analysis; Animals; Arachis / chemistry; Arachis / microbiology; Aspartate Aminotransferases / blood; Bacillus subtilis; Chickens; Dietary Supplements; Duodenum / chemistry; Food Contamination / analysis; Glutathione Peroxidase / blood; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Protective Agents / pharmacology
TL;DR: The supplementation of AnSB060 reduced aflatoxin levels in the duodenum and counteracted the negative effects of aflatoxins, leading to the conclusion that ANSB060 has a protective effect against aflatoxicosis and this protection is dose-related. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Supplementation of Maternal Diets with Choline, B‐vitamin and Docosahexaenoic Acid (DHA) Alters Gene Expressions Associated with Hepatic Lipid Metabolism in Offspring

The FASEB Journal, 29(S1).

By: L. Xi n, C. Man n, H. Lima n, S. Jacobi n, S. Lui n & J. Odle n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: February 20, 2022

2015 journal article

Transplacental induction of fatty acid oxidation in term fetal pigs by the peroxisome proliferator-activated receptor alpha agonist clofibrate

Journal of Animal Science and Biotechnology, 6(1).

By: X. Lin n, S. Jacobi n & J. Odle n

Contributors: X. Lin n, S. Jacobi n & J. Odle n

author keywords: Clofibrate; Fatty acid oxidation; Pigs; Placenta transfer
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2014 journal article

Clofibrate Increases Long-Chain Fatty Acid Oxidation by Neonatal Pigs

The Journal of Nutrition, 144(11), 1688–1693.

By: X. Bai n, X. Lin n, J. Drayton n, Y. Liu n, C. Ji* & J. Odle n

Contributors: X. Bai n, X. Lin n, J. Drayton n, Y. Liu n, C. Ji* & J. Odle n

MeSH headings : Animals; Animals, Newborn; Anticholesteremic Agents / pharmacology; Clofibrate / pharmacology; Fatty Acids / metabolism; Liver / drug effects; Liver / metabolism; Male; Oxidation-Reduction / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Weight Gain
TL;DR: Clofibrate may improve in vivo LCFA oxidative utilization in neonatal pigs to increase efficiency of milk fat utilization by newborn pigs. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2014 journal article

Dietary supplementation of aspartate enhances intestinal integrity and energy status in weanling piglets after lipopolysaccharide challenge

The Journal of Nutritional Biochemistry, 25(4), 456–462.

By: D. Pi*, Y. Liu*, H. Shi*, S. Li*, J. Odle n, X. Lin n, H. Zhu*, F. Chen* ...

Contributors: D. Pi*, Y. Liu*, H. Shi*, S. Li*, J. Odle n, X. Lin n, H. Zhu*, F. Chen*, Y. Hou*, W. Leng*

author keywords: Aspartate; Intestine; Energy status; Weanling piglets; Lipopolysaccharide
MeSH headings : AMP-Activated Protein Kinases / genetics; AMP-Activated Protein Kinases / metabolism; Adenosine Diphosphate / metabolism; Adenosine Monophosphate / metabolism; Adenosine Triphosphate / metabolism; Animals; Aspartic Acid / pharmacology; Body Weight / drug effects; DNA / metabolism; Dietary Supplements; Histone Deacetylases / genetics; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestines / drug effects; Lactase / metabolism; Lipopolysaccharides / toxicity; Phosphorylation / drug effects; Proteins / metabolism; Sucrase / metabolism; Swine; Transcription Factors / genetics; Weaning
TL;DR: Results indicate that Asp may alleviate LPS-induced intestinal damage and improve intestinal energy status. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2014 journal article

Differential expression of heat shock transcription factors and heat shock proteins after acute and chronic heat stress in laying chickens (Gallus gallus)

PLoS One, 9(7), e102204.

Contributors: J. Xie*, L. Tang*, L. Lu*, L. Zhang*, L. Xi, H. Liu n, J. Odle n, X. Luo*

Ed(s): S. Cotterill

MeSH headings : Animals; Behavior, Animal; Chickens / genetics; Chickens / metabolism; DNA-Binding Proteins / genetics; Female; Gene Expression Regulation; HSP70 Heat-Shock Proteins / genetics; HSP90 Heat-Shock Proteins / genetics; Heat Shock Transcription Factors; Heat-Shock Proteins / genetics; Heat-Shock Response / genetics; Male; Malondialdehyde / metabolism; RNA, Messenger; Superoxide Dismutase / metabolism; Temperature; Time Factors; Transcription Factors / genetics
TL;DR: The differential expressions of HSF and HSP genes in different tissues of laying broiler breeder chickens suggested that anti-heat stress mechanisms might be provoked more profoundly in the heart, by which the muscle was least protected during heat stress. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Effects of Supplemental Copper on the Serum Lipid Profile, Meat Quality, and Carcass Composition of Goat Kids

Biological Trace Element Research, 159(1-3), 140–146.

author keywords: Carcass composition; Copper; Goat; Meat quality; Serum lipid profile
MeSH headings : Animal Feed; Animals; Body Composition / drug effects; Copper / pharmacology; Dietary Supplements; Goats; Lipid Metabolism / drug effects; Male; Meat / analysis
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2014 conference paper

Effects of methylating vitamins and docosahexaenoic acid supplementation on biological molecular, and genomic characteristics of intra-uterine growth restriction (IUGR) in a feed-restricted swine model

Swine in Biomedical Research, 60.

By: H. Lima, S. Jacobi, C. Man, K. Walker, J. Sommer, W. Flowers, A. Blikslager, L. Gonzalez, L. Xi, J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2014 journal article

Effects of methylating vitamins and docosahexaenoic acid supplementation on intra‐uterine growth retardation in a feed‐restricted swine model

The FASEB Journal, 28(S1).

By: H. Lima n, S. Jacobi n, C. Man n, K. Walker n, J. Sommer n, W. Flowers n, A. Blikslager n, L. Xi n, J. Odle n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: February 20, 2022

2014 conference paper

Maternal supplementation of choline, B-vitamins and docosahexaneoic acid (DHA) during global nutrient restriction alter abundance of miRNA and mRNA associated with hepatic lipid metabolism in term fetal piglets

Swine in Biomedical Research, 108.

By: C. Man, L. Xi, H. Lima, S. Jacobi, C. Resnyk, S. Liu, J. Odle

Event: Swine in Biomedical Research

Source: NC State University Libraries
Added: May 5, 2022

2014 journal article

Methylated Medium‐ and Long‐Chain Fatty Acids Provide Novel Sources of Anaplerotic Carbon for Fasting or Exercising Mice

The FASEB Journal, 28(S1).

By: J. Drayton n, X. Lin n, S. Jacobi n, R. Shanely*, M. McIntosh* & J. Odle n

TL;DR: Results were consistent with the hypothesis that methyl‐branched fatty acids may provide anaplerotic carbon and thereby stimulate in vitro fatty acid oxidation and are consistent with previous studies of methylated fatty acids using TCA cycle intermediates. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2014 speech

Nutritional innovations for alleviating stress--The stress induced by high temperature and malnutrition

Presented at the Institute of Animal Science and Veterinary Science, Beijing, CAAS.

By: X. Lin

Event: Institute of Animal Science and Veterinary Science at Beijing, CAAS

Source: NC State University Libraries
Added: May 5, 2022

2014 speech

The Critical Role of Lipid Metabolism in Neonatal Pigs

Presented at the South-Central University for Nationalities and Henan Institute of Science and Technology, Wuhan Polytechnic University (WHPU).

By: X. Lin & J. Odle

Event: South-Central University for Nationalities and Henan Institute of Science and Technology at Wuhan Polytechnic University (WHPU)

Source: NC State University Libraries
Added: May 5, 2022

2014 journal article

The Suckling Piglet as an Agrimedical Model for the Study of Pediatric Nutrition and Metabolism

Annual Review of Animal Biosciences, 2(1), 419–444.

By: J. Odle n, X. Lin n, S. Jacobi n, S. Kim n & C. Stahl n

Contributors: J. Odle n, X. Lin n, S. Jacobi n, S. Kim n & C. Stahl n

author keywords: agrimedical; milk; infant; fatty acid; oligosaccharide; amino acid; calcium; phosphorous
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Child; Child Nutritional Physiological Phenomena; Humans; Swine / physiology
TL;DR: The broad scope of this review is to outline the fundamental elements of the piglet model and to highlight key aspects of relevance to various macronutrients, including lipids, carbohydrates, proteins/amino acids, and calcium/phosphorus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Conjugated Linoleic Acid Reduces Adiposity and Increases Markers of Browning and Inflammation in White Adipose Tissue of Mice

The FASEB Journal, 27(S1).

By: W. Shen*, C. Chuang*, K. Martinez*, T. Reid*, J. Brown*, L. Xi n, L. Hixson*, J. Starnes*, M. McIntosh*

TL;DR: Data suggest a linkage between decreased adiposity, browning in WAT, and low‐grade inflammation due to consumption of 10,12 CLA, a mechanism by which conjugated linoleic acid reduces body fat. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 21, 2022

2013 journal article

Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice

Journal of Lipid Research, 54(4), 909–922.

By: W. Shen*, C. Chuang*, K. Martinez*, T. Reid*, J. Brown*, L. Xi n, L. Hixson*, R. Hopkins*, J. Starnes*, M. McIntosh*

author keywords: obesity; weight loss supplement; glucose tolerance; uncoupling protein; steatosis
MeSH headings : Adipose Tissue, White / drug effects; Adipose Tissue, White / metabolism; Adiposity / drug effects; Animals; Fatty Acids / metabolism; Gas Chromatography-Mass Spectrometry; Immunoblotting; Inflammation / metabolism; Linoleic Acid / pharmacology; Linoleic Acids, Conjugated / pharmacology; Liver / drug effects; Liver / metabolism; Male; Mice; Real-Time Polymerase Chain Reaction; Triglycerides / metabolism
TL;DR: Data suggest a linkage between decreased adiposity, browning in WAT, and low-grade inflammation due to consumption of 10,12 CLA. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Diet physical form, fatty acid chain length, and emulsification alter fat utilization and growth of newly weaned pigs

Journal of Animal Science, 91(2), 783–792.

By: K. Price n, X. Lin n, E. van Heugten n, R. Odle n, G. Willis & J. Odle n

Contributors: K. Price n, X. Lin n, E. Van Heugten n, R. Odle n, G. Willis & J. Odle n

author keywords: emulsification; fat digestibility; medium chain triglyceride; milk replacer; pigs
MeSH headings : Animal Feed / analysis; Animals; Bile Acids and Salts / physiology; Diet / veterinary; Dietary Fats / metabolism; Digestion / physiology; Fatty Acids / chemistry; Female; Jejunum / physiology; Ketone Bodies / blood; Male; Swine / growth & development; Swine / physiology; Weaning
TL;DR: It is concluded that feeding liquid diets containing emulsified LCT can improve fat utilization and markedly accentuate feed intake, growth, and G:F of weanling pigs. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Dietary supplementation of Bifidobacterium longum strain AH1206 increases its cecal abundance and elevates intestinal interleukin-10 expression in the neonatal piglet

Food and Chemical Toxicology, 60, 116–122.

By: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski*, C. Stahl n, J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski*, C. Stahl n, J. Odle n

author keywords: Bifidobacteria; Probiotic; Infant; Intestinal health; Immune system; IL-10
MeSH headings : Animal Feed / microbiology; Animals; Animals, Newborn; Bifidobacterium; Cecum / microbiology; Colony Count, Microbial; Dietary Supplements; Immunoglobulin G / blood; Immunoglobulin M / blood; Interleukin-10 / genetics; Interleukin-10 / metabolism; Probiotics / administration & dosage; Swine; Weight Gain
TL;DR: Dietary supplementation with B. longum (AH1206) may be safe for human infants based on a lack of growth, development or deleterious immune-related effects observed in piglets, based on findings in the suckling piglet model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Early postnatal kinetics of colostral immunoglobulin G absorption in fed and fasted piglets and developmental expression of the intestinal immunoglobulin G receptor

Journal of Animal Science, 91(1), 211–218.

By: R. Cabrera n, X. Lin n, M. Ashwell n, A. Moeser n & J. Odle n

Contributors: R. Cabrera n, X. Lin n, M. Ashwell n, A. Moeser n & J. Odle n

author keywords: colostral immunoglobulin G; immunoglobulin G receptor; serum immunoglobulin G
MeSH headings : Absorption; Animals; Animals, Newborn; Colostrum / chemistry; Food Deprivation; Gene Expression Regulation, Developmental / drug effects; Immunoglobulin G / administration & dosage; Immunoglobulin G / chemistry; Intestinal Mucosa / metabolism; Intestines / drug effects; Receptors, IgG / genetics; Receptors, IgG / metabolism; Swine / metabolism
TL;DR: The effects of delayed offering of defatted colostrum and age-dependent changes in IgG receptor were modest over the first 24 h of life. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Effect of copper on performance, carcass characteristics, and muscle fatty acid composition of meat goat kids

Journal of Animal Science, 91(10), 5004–5010.

By: Y. Huang*, Y. Wang*, J. Spears n, X. Lin n & C. Guo*

author keywords: carcass characteristics; copper; fatty acid composition; meat goat kids; performance
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Body Composition / drug effects; Copper / pharmacology; Diet / veterinary; Fatty Acids / genetics; Fatty Acids / metabolism; Goats / growth & development; Goats / physiology; Male; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism; Reference Values
TL;DR: The results indicate that JYB goats can tolerate up to 640 mg Cu/kg DM for 96 d without adverse effects on performance, but fat deposition and fatty acid composition in the body could be altered by Cu supplementation as low as 20 mg/kg of diet with high concentrate-hay. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Effect of dietary selenium on boar sperm quality

Animal Reproduction Science, 138(3-4), 268–275.

By: K. Lovercamp n, K. Stewart n, X. Lin n & W. Flowers n

author keywords: Boar; Selenium; Sperm; Lipid peroxidation; Glutathione peroxidise
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena / drug effects; Animals; Cell Shape / drug effects; Dietary Supplements; Fatty Acids / analysis; Fatty Acids / metabolism; Glutathione Peroxidase / analysis; Glutathione Peroxidase / metabolism; Lipid Peroxidation / drug effects; Male; Selenium / administration & dosage; Selenium / analysis; Semen / chemistry; Semen / cytology; Semen / drug effects; Semen / metabolism; Semen Analysis / veterinary; Semen Preservation / veterinary; Swine / metabolism; Swine / physiology
TL;DR: Results indicate that supplementing a basal diet with organic or inorganic selenium did not affect semen quantity or sperm quality in fresh ejaculates nor did it appear to have any beneficial latent effects in extended semen stored post collection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Fish Oil Alleviates Activation of the Hypothalamic-Pituitary-Adrenal Axis Associated with Inhibition of TLR4 and NOD Signaling Pathways in Weaned Piglets after a Lipopolysaccharide Challenge

The Journal of Nutrition, 143(11), 1799–1807.

By: Y. Liu*, F. Chen*, Q. Li*, J. Odle n, X. Lin n, H. Zhu*, D. Pi*, Y. Hou* ...

MeSH headings : Adrenal Glands / drug effects; Adrenal Glands / metabolism; Adrenocorticotropic Hormone / blood; Animals; Corticotropin-Releasing Hormone / blood; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Disease Models, Animal; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Fish Oils / pharmacology; Hypothalamo-Hypophyseal System / drug effects; Hypothalamo-Hypophyseal System / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1 Receptor-Associated Kinases / metabolism; Lipopolysaccharides / toxicity; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; Nod Signaling Adaptor Proteins / antagonists & inhibitors; Nod Signaling Adaptor Proteins / genetics; Nod Signaling Adaptor Proteins / metabolism; Pituitary Gland / drug effects; Pituitary Gland / metabolism; Pituitary-Adrenal System / drug effects; Pituitary-Adrenal System / metabolism; Pro-Opiomelanocortin / blood; RNA, Messenger / genetics; RNA, Messenger / metabolism; Spleen / drug effects; Spleen / metabolism; Swine; Thymus Gland / drug effects; Thymus Gland / metabolism; Toll-Like Receptor 4 / antagonists & inhibitors; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism; Weaning
TL;DR: Dietary treatment with fish oil could mitigate LPS-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis through inhibition of Toll-like receptor 4 and nucleotide-binding oligomerization domain protein signaling pathways, and the beneficial effects of FO on the HPA axis may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Fish Oil Increases Muscle Protein Mass and Modulates Akt/FOXO, TLR4, and NOD Signaling in Weanling Piglets After Lipopolysaccharide Challenge

The Journal of Nutrition, 143(8), 1331–1339.

MeSH headings : Animals; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Docosahexaenoic Acids / administration & dosage; Eicosapentaenoic Acid / administration & dosage; Fish Oils / administration & dosage; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Lipopolysaccharides / adverse effects; Muscle Proteins / metabolism; Muscle, Skeletal / drug effects; Muscle, Skeletal / metabolism; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Nod1 Signaling Adaptor Protein / genetics; Nod1 Signaling Adaptor Protein / metabolism; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction / drug effects; Swine; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism
TL;DR: Results indicate fish oil may suppress muscle proinflammatory cytokine production via regulation of TLR and NOD signaling pathways and therefore improve muscle protein mass, possibly through maintenance of Akt/FOXO signaling. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 conference paper

Improving health of small infants via nutritional epigenetics

Lin, X., Lima, H., & Odle, J. (2013, March 13). Presented at the GCE Agriculture & Nutrition Awardee Convening, Seattle, WA.

By: X. Lin, H. Lima & J. Odle

Event: GCE Agriculture & Nutrition Awardee Convening at Seattle, WA on March 13-15, 2013

Source: NC State University Libraries
Added: May 5, 2022

2013 conference paper

Recent advances in polyunsaturated fatty acid nutrition and metabolism in swine

Presented at the WCAP meeting, Beijing, China.

By: J. Odle, X. Lin, S. Jacobi & Y. Liu

Event: WCAP meeting at Beijing, China

Source: NC State University Libraries
Added: May 5, 2022

2013 journal article

Relative bioavailabilities of organic zinc sources with different chelation strengths for broilers fed diets with low or high phytate content

ANIMAL FEED SCIENCE AND TECHNOLOGY, 179(1-4), 144–148.

By: Y. Huang*, L. Lu*, J. Xie*, S. Li*, X. Li*, S. Liu*, L. Zhang*, L. Xi, X. Luo*

author keywords: Broilers; Dietary phytate; Organic Zn; Relative bioavailability
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Stabilized rice bran improves weaning pig performance via a prebiotic mechanism

Journal of Animal Science, 91(2), 907–913.

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, E. Heugten n, V. Fellner n & J. Odle n

author keywords: antibiotics; gastrointestinal; microbiota; stabilized rice bran; swine
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Diet / veterinary; Intestines / anatomy & histology; Oryza / chemistry; Prebiotics; Swine / growth & development
TL;DR: SRB improved the efficiency of nutrient utilization in nursery diets lacking antibiotics and tended to increase intestinal bifidobacteria concentrations, indicating that SRB may exert beneficial prebiotic effects in weanling pigs. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2012 journal article

Clofibrate increases in vivo fatty acid oxidation by neonatal pigs

The FASEB Journal, 26(S1).

By: X. Bai n, L. Xi, J. Drayton n, C. Ji* & J. Odle n

Sources: Crossref, ORCID
Added: February 21, 2022

2012 speech

Clofibrate increases in vivo fatty acid oxidation by neonatal pigs

Presented at the China Agricultural University.

By: X. Bai, L. Xi, J. Drayton, C. Ji & J. Odle

Event: China Agricultural University

Source: NC State University Libraries
Added: May 5, 2022

2012 speech

Correlations between infant and pig nutrition and health

Presented at the Scientists Without Borders, Bill & Melinda Gates Foundation.

By: J. Odle & X. Lin

Event: Scientists Without Borders, Bill & Melinda Gates Foundation

Source: NC State University Libraries
Added: May 5, 2022

2012 journal article

Fish Oil Enhances Intestinal Integrity and Inhibits TLR4 and NOD2 Signaling Pathways in Weaned Pigs after LPS Challenge

The Journal of Nutrition, 142(11), 2017–2024.

MeSH headings : Animal Feed / analysis; Animals; Diet / veterinary; Docosahexaenoic Acids / chemistry; Docosahexaenoic Acids / metabolism; Eicosapentaenoic Acid / chemistry; Eicosapentaenoic Acid / metabolism; Fatty Acids, Omega-3 / genetics; Fatty Acids, Omega-3 / metabolism; Fish Oils / pharmacology; Gene Expression Regulation / drug effects; Intestinal Diseases / chemically induced; Intestinal Diseases / metabolism; Intestinal Mucosa; Intestines / drug effects; Lipopolysaccharides / toxicity; Nod2 Signaling Adaptor Protein / genetics; Nod2 Signaling Adaptor Protein / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Real-Time Polymerase Chain Reaction; Swine / metabolism; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism
TL;DR: Results indicate that fish oil supplementation is associated with inhibition of TLR4 and NOD2 signaling pathways and concomitant improvement of intestinal integrity under an inflammatory condition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2012 journal article

Influence of birth order, birth weight, colostrum and serum immunoglobulin G on neonatal piglet survival

Journal of Animal Science and Biotechnology, 3(1).

By: R. Cabrera n, X. Lin n, J. Campbell, A. Moeser n & J. Odle n

Contributors: R. Cabrera n, X. Lin n, J. Campbell, A. Moeser n & J. Odle n

author keywords: Birth order; Birth weight; Immunoglobulin G; Colostrum; Survivability
TL;DR: The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Sources: Crossref, ORCID
Added: November 19, 2019

2012 chapter

Lipids and Lipid Utilization in Swine

In Sustainable Swine Nutrition (pp. 59–79).

By: X. Lin n, M. Azain n & J. Odle n

Contributors: X. Lin n, M. Azain n & J. Odle n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: November 19, 2019

2012 journal article

Manganese source affects manganese transport and gene expression of divalent metal transporter 1 in the small intestine of broilers

British Journal of Nutrition, 108(2), 267–276.

By: S. Bai*, L. Lu*, R. Wang*, L. Xi n, L. Zhang* & X. Luo*

author keywords: Organic manganese transport; Divalent metal transporter; Gene expression; Small-intestinal loops; Broilers
MeSH headings : Amino Acids / chemistry; Animal Feed / analysis; Animals; Avian Proteins / genetics; Avian Proteins / metabolism; Cation Transport Proteins / genetics; Cation Transport Proteins / metabolism; Chelating Agents / administration & dosage; Chelating Agents / chemistry; Chickens / blood; Chickens / growth & development; Chickens / metabolism; China; Deficiency Diseases / diet therapy; Deficiency Diseases / metabolism; Deficiency Diseases / veterinary; Duodenum / growth & development; Duodenum / metabolism; Gene Expression Regulation; Intestinal Absorption; Intestine, Small / growth & development; Intestine, Small / metabolism; Kinetics; Male; Manganese / administration & dosage; Manganese / deficiency; Manganese / metabolism; Manganese / therapeutic use; Manganese Compounds / administration & dosage; Organ Specificity; Osmolar Concentration; Poultry Diseases / diet therapy; Poultry Diseases / metabolism; Sulfates / administration & dosage
TL;DR: Results indicated that organic Mn sources with stronger Qf showed higher Mn transport and absorption, and DMT1 might be involved in the regulation of organic Mn transport in the proximal small intestine of broilers. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 14, 2021

2012 speech

The Effect of cofibrate on renal fatty acid oxidation in neonatal pigs

Presented at the 21st Annual NC State Undergraduate Research Symposium.

By: I. Khan & L. Xi

Event: 21st Annual NC State Undergraduate Research Symposium

Source: NC State University Libraries
Added: May 5, 2022

2012 journal article

The effect of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) on fatty acid oxidation in hepatocytes isolated from neonatal piglets

Journal of Animal Science and Biotechnology, 3(1).

By: L. Xi n, G. Matsey n & J. Odle n

Contributors: L. Xi n, G. Matsey n & J. Odle n

author keywords: Suckled neonatal pig; 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR); Carnitine palmitoyltransferase (CPT); Acetyl-CoA carboxylase (ACC)
TL;DR: AICAR may affect the distribution of metabolic products from fatty acid oxidation by changing ACC activity in hepatocyte isolated from suckled neonatal piglets; however, the basis for the increase in ACC activity elicited by AICAR is not apparent. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 19, 2019

2011 conference paper

A porcine model studying prophylaxis and treatment of neonatal enteric disease with long chain PUFA

Swine in Biomedical Research Conference, 49.

By: S. Jacobi, A. Moeser, L. Xi, A. Blikslager & J. Odle

Event: Swine in Biomedical Research Conference at Chicago, IL

Source: NC State University Libraries
Added: May 5, 2022

2011 journal article

An estimation of the manganese requirement for broilers from 1 to 21 days of age

Biological Trace Element Research, 143(2), 939–948.

By: S. Li*, Y. Lin*, L. Lu*, L. Xi, Z. Wang*, S. Hao*, L. Zhang*, K. Li n, X. Luo*

author keywords: Manganese; Requirement; MnSOD mRNA; Broiler
MeSH headings : Animals; Chickens; Dietary Supplements; Manganese / administration & dosage; Manganese / metabolism; Myocardium / metabolism; Pancrelipase / metabolism; Superoxide Dismutase / genetics
TL;DR: Heart MnSOD mRNA concentration was a consistent index for the estimation of the Mn requirement of broilers, and the estimate of dietary Mn requirement for broilers from 1 to 21 days of age post-hatching was about 130 mg/kg, which was a little more than two times of the current NRC (1994) requirement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Dietary Arachidonate Differentially Alters Desaturase-Elongase Pathway Flux and Gene Expression in Liver and Intestine of Suckling Pigs

The Journal of Nutrition, 141(4), 548–553.

By: S. Jacobi n, X. Lin n, B. Corl n, H. Hess n, R. Harrell n & J. Odle n

Contributors: S. Jacobi n, X. Lin n, B. Corl n, H. Hess n, R. Harrell n & J. Odle n

MeSH headings : Acetyltransferases / genetics; Acetyltransferases / metabolism; Animals; Animals, Suckling; Arachidonic Acid / administration & dosage; Delta-5 Fatty Acid Desaturase; Fatty Acid Desaturases / genetics; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids / metabolism; Intestinal Mucosa / metabolism; Linoleoyl-CoA Desaturase / genetics; Linoleoyl-CoA Desaturase / metabolism; Liver / metabolism; Organ Specificity; Protein Transport; RNA, Messenger / analysis; Swine
TL;DR: D dietary ARA regulated the desaturase-elongase pathway in a tissue-specific manner in liver and intestine, and had modest effects on (n-6) fatty acid flux, and intestinal FADS2 activity and mRNA increased. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2011 journal article

Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs

The Journal of Nutritional Biochemistry, 22(11), 1047–1054.

By: X. Lin n, J. Bo n, S. Oliver n, B. Corl n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n

Contributors: X. Lin n, J. Bo n, S. Oliver n, B. Corl n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n

MeSH headings : Acetyltransferases / metabolism; Animals; Animals, Newborn; Arachidonic Acid / metabolism; Brain / metabolism; Dietary Fats / administration & dosage; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids, Unsaturated / metabolism; Linoleic Acid / metabolism; Linoleic Acids, Conjugated / pharmacology; Liver / metabolism; Swine
TL;DR: Overall, the data show that dietary CLA shifted the distribution of the synthetic products of [U-(13)C]LA between elongation and desaturation in liver and decreased the total synthetic products in brain by inhibiting LA elongation to C20:2n-6. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Effects of 9‐cis‐retinoic acid on fatty acid oxidation induced by clofibrate in primary cultured heptocytes from newborn pigs

The FASEB Journal, 25(S1).

By: Y. Liu n, L. Xi n, T. Herfel n, S. Jacobi n & J. Odle n

TL;DR: The results indicate that clofibrate strongly induces fatty acid oxidation in pig primary cultured hepatocyte, but the induction was not affected by addition of RA. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 21, 2022

2011 journal article

Effects of alpha-lipoic acid supplementation on antioxidative ability and performance of sows and nursing piglets

Journal of Animal Physiology and Animal Nutrition, 96(6), 955–961.

By: X. Bai*, Q. Ma, L. Zhao*, L. Xi n & C. Ji*

author keywords: alpha-lipoic acid; antioxidative ability; performance; piglet; sow
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling / growth & development; Antioxidants / metabolism; Diet / veterinary; Dietary Supplements; Female; Maternal Nutritional Physiological Phenomena; Pregnancy; Swine / growth & development; Thioctic Acid / administration & dosage; Thioctic Acid / pharmacology
TL;DR: Results indicate that antioxidant LA was effective in enhancing antioxidant enzymes activity and improving the performance of sows and their nursing piglets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Effects of supplemental zinc source and level on growth performance, carcass traits, and meat quality of broilers

Poultry Science, 90(8), 1782–1790.

By: Z. Liu*, L. Lu*, S. Li, L. Zhang*, L. Xi n, K. Zhang*, X. Luo*

author keywords: zinc; growth performance; carcass trait; meat quality; broiler
MeSH headings : Animal Feed / analysis; Animals; Body Composition; Chickens / growth & development; Diet / veterinary; Dietary Supplements; Hydrogen-Ion Concentration; Meat / standards; Zinc / pharmacology
TL;DR: Results from this study indicated that Zn could promote growth and improve production performance of broilers independent of Zn source. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Evaluation of the nutritional value of glycerol for nursery pigs

Journal of Animal Science, 89(7), 2145–2153.

Contributors: M. Shields n, E. Heugten n, X. Lin n, J. Odle n & C. Stark n

author keywords: glycerol; lactose; nursery; pig
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Diet / veterinary; Female; Glycerol / administration & dosage; Glycerol / pharmacology; Lactose; Lethal Dose 50; Male; Swine / growth & development; Weight Gain; Zea mays
TL;DR: Overall, data indicate that glycerol can be added to nursery pig diets at 10%, while improving growth performance, and there was no effect of feeding Glycerol during the starter 1 phase on subsequent performance during thestarter 2 phase or overall. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2011 speech

Piglet Model of Pediatric Nutrition and Metabolism

By: J. Odle, S. Jacobi & X. Lin

Source: NC State University Libraries
Added: May 5, 2022

2011 conference paper

Piglet model of pediatric nutrition and metabolism

Swine in Biomedical Research Conference, 22.

By: J. Odle, S. Jacobi & X. Lin

Event: Swine in Biomedical Research Conference at Chicago, IL

Source: NC State University Libraries
Added: May 5, 2022

2011 journal article

Polydextrose Enrichment of Infant Formula Demonstrates Prebiotic Characteristics by Altering Intestinal Microbiota, Organic Acid Concentrations, and Cytokine Expression in Suckling Piglets

The Journal of Nutrition, 141(12), 2139–2145.

By: T. Herfel n, S. Jacobi n, X. Lin n, V. Fellner n, D. Walker*, Z. Jouni*, J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, V. Fellner n, D. Walker*, Z. Jouni*, J. Odle n

MeSH headings : Animals; Animals, Newborn / growth & development; Bifidobacterium / drug effects; Bifidobacterium / growth & development; Cytokines / drug effects; Cytokines / genetics; Cytokines / metabolism; Food, Fortified; Glucans / administration & dosage; Glucans / analysis; Humans; Infant; Infant Food; Infant Formula / chemistry; Intestines / microbiology; Lactic Acid / analysis; Lactobacillus / drug effects; Lactobacillus / growth & development; Metagenome; Milk, Human / chemistry; Models, Animal; Oligosaccharides / administration & dosage; Oligosaccharides / analysis; Prebiotics; Propionates / analysis; RNA / isolation & purification; RNA, Messenger; Real-Time Polymerase Chain Reaction; Swine
TL;DR: PDX enrichment of infant formula resulted in a prebiotic effect by increasing ileal lactobacilli and propionic and lactic acid concentrations and decreasing pH with associated alterations in ileale cytokine expression. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2011 journal article

Safety of novel Bifidobacterium strains demonstrated in a human infant surrogate, the neonatal pig

FASEB Journal, 25(584), 16.

By: T. Herfel, S. Jacobi, X. Lin, C. Walker, M. Russell, C. Stahl, J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2010 journal article

Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid β-oxidation in liver of neonatal swine

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 298(5), R1435–R1443.

By: X. Lin n, K. Shim n & J. Odle n

Contributors: X. Lin n, K. Shim n & J. Odle n

author keywords: acetate; anaplerosis; carnitine palmitoyltransferase I activity; ketone bodies; mitochondria; Sus scrofa
MeSH headings : Acetates / metabolism; Acetyl-CoA Hydrolase / metabolism; Age Factors; Animals; Animals, Suckling; Carbon Radioisotopes; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Citric Acid / metabolism; Citric Acid Cycle / physiology; Enzyme Activation / physiology; Fatty Acids / metabolism; Gene Expression Regulation, Enzymologic; Ketone Bodies / metabolism; Liver / enzymology; Malonyl Coenzyme A / metabolism; Mitochondria / metabolism; Mitochondria, Liver / enzymology; Oxidation-Reduction; Palmitates / pharmacokinetics; Palmitoyl Coenzyme A / metabolism; RNA, Messenger / metabolism; Sus scrofa / metabolism
TL;DR: It is demonstrated that acetate is the primary product of hepatic mitochondrial beta-oxidation in Sus scrofa and that regulation during early development is mediated primarily via kinetic modulation of CPT I. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2010 journal article

Effects of age and strain on the expression of leptin receptor, neuropeptide Y and pro-opiomelanocortin in the hypothalamus of young chickens

British Poultry Science, 51(5), 696–702.

MeSH headings : Age Factors; Animals; Avian Proteins / genetics; Avian Proteins / metabolism; Body Weight; Chickens / growth & development; Chickens / metabolism; Chickens / physiology; Hypothalamus / metabolism; Hypothalamus / physiology; Neuropeptide Y / genetics; Neuropeptide Y / metabolism; Pro-Opiomelanocortin / genetics; Pro-Opiomelanocortin / metabolism; RNA, Messenger / metabolism; Receptors, Leptin / genetics; Receptors, Leptin / metabolism
TL;DR: The results showed that the developmental changes of hypothalamic signal molecules varied with age and strain, suggesting that NPY, α-MSH and leptin receptor might be involved in the early programming of feed intake in newly hatched chickens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Effects of zinc source and phytate on zinc absorption by in situ ligated intestinal loops of broilers

Poultry Science, 89(10), 2157–2165.

By: Y. Yu*, L. Lu*, R. Wang*, L. Xi n, X. Luo* & B. Liu*

author keywords: absorption; broiler; organic zinc; phytate; small intestine
MeSH headings : Absorption; Animals; Intestinal Absorption / drug effects; Intestinal Absorption / physiology; Intestine, Small / metabolism; Phytic Acid / pharmacology; Zinc / chemistry; Zinc / pharmacokinetics
TL;DR: The results indicated that the absorption of Zn as organic Zn was more effective than that ofZn as inorganic Zn under the high levels of phytate. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Polydextrose enrichment of infant formula acts as a prebiotic by increasing ileal lactobacilli and lactic acid concentration and decreasing pH

The FASEB Journal, 24(S1).

By: T. Herfel n, S. Jacobi n, X. Lin n, D. Walker*, Z. Jouni* & J. Odle n

TL;DR: Polydextrose enrichment of infant formula acted as a prebiotic by increasing lactic acid production and decreasing pH in pigs by acting as aPrebiotic supplement to human milk oligosaccharides. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2010 journal article

Production of value-added pork by enrichment with omega-3 fatty acids

Journal of Animal Science, 88(E-Suppl. 3), 72.

By: C. Brown, X. Lin, E. van Heugten, R. Harrell, D. Hanson & J. Odle

Event: Midwest Regional Animal Science Meetings at Des Moines, IA

Source: NC State University Libraries
Added: May 5, 2022

2010 journal article

The effect of feeding sow colostrum on IgG absorption, intestinal morphology and expression of IgG receptor (FcRn) and β2-microglobulin (β2M) in neonatal piglets

Journal of Animal Science, 88(E-Suppl. 3), 100.

By: R. Cabrera, X. Lin, A. Taro, M. Ashwell, A. Moeser & J. Odle

Event: Midwest Regional Animal Science Meetings at Des Moines, IA.

Source: NC State University Libraries
Added: May 5, 2022

2009 conference paper

Birth Order, Birth Weight, Sow Colostrum IgG and Pig IgG Concentration and their effects on Neonatal Piglet Survival

Presented at the ADSA - ASAS - CSAS Joint Annual Meeting.

By: R. Cabrera, X. Lin, K. Shim, T. Inskeep, J. Campbell & J. Odle

Event: ADSA - ASAS - CSAS Joint Annual Meeting on July 12-16, 2009

Source: NC State University Libraries
Added: May 5, 2022

2009 journal article

Clofibrate induces expression of hepatic genes encoding fatty acid oxidation and ketogenesis enzymes in pigs during early postnatal development

The FASEB Journal, 23(S1).

By: K. Shim n, L. Xi n, S. Jacobi n & J. Odle n

TL;DR: Clofibrate strongly induces genes of fatty acid oxidation in the young, postnatal pig, but induction is not influenced by developmental age. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 21, 2022

2009 conference paper

Clofibrate treatment up-regulates hepatic gene expression encoding fatty acid oxidation and ketogenesis enzymes in liver of pigs during early postnatal development

Presented at the ADSA - ASAS - CSAS Joint Annual Meeting.

By: K. Shim, L. Xi, S. Jacobi & J. Odle

Event: ADSA - ASAS - CSAS Joint Annual Meeting on July 12-16, 2009

Source: NC State University Libraries
Added: May 21, 2022

2009 journal article

Ontogeny of the desaturase‐elongase pathway in neonatal pigs fed arachidonic acid

The FASEB Journal, 23(S1).

Sources: Crossref, ORCID
Added: February 20, 2022

2009 journal article

Safety evaluation of polydextrose in infant formula using a suckling piglet model

Food and Chemical Toxicology, 47(7), 1530–1537.

By: T. Herfel n, S. Jacobi n, X. Lin n, D. Walker*, Z. Jouni* & J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, D. Walker*, Z. Jouni* & J. Odle n

author keywords: Polydextrose; Prebiotic; Infant; Oligosaccharide; Soluble fiber
MeSH headings : Amylases / analysis; Amylases / metabolism; Animals; Animals, Suckling; Blood Cell Count; Blood Chemical Analysis; Body Weight / drug effects; DNA / biosynthesis; Diet; Feces / chemistry; Food Additives / toxicity; Glucans / toxicity; Health Status; Humans; Infant; Infant Food / toxicity; Organ Size / drug effects; Pancreas / drug effects; Pancreas / metabolism; Swine
TL;DR: Polydextrose mimicked other prebiotic carbohydrates and had no adverse effect at the highest tested level 17.0 g PDX/L, equivalent to a dose of 8.35 g/kg of body weight per day. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2008 journal article

Conjugated Linoleic Acid Reduces Body Fat Accretion and Lipogenic Gene Expression in Neonatal Pigs Fed Low- or High-Fat Formulas

The Journal of Nutrition, 138(3), 449–454.

By: B. Corl n, S. Mathews Oliver n, X. Lin n, W. Oliver n, Y. Ma n, R. Harrell n, J. Odle n

MeSH headings : Adipose Tissue / drug effects; Adipose Tissue / metabolism; Animals; Animals, Newborn; Body Composition / drug effects; Dietary Fats / pharmacology; Dietary Supplements; Digestion; Feeding Behavior; Gene Expression Regulation / drug effects; Infant Formula; Linoleic Acids, Conjugated / pharmacology; Lipid Metabolism / drug effects; Lipogenesis / drug effects; Lipogenesis / genetics; Liver / metabolism; Muscle, Skeletal / metabolism; Swine; Weight Gain
TL;DR: Overall, CLA reduced body fat accretion without influencing daily gain in a piglet model of human infancy, indicating that inhibition of fatty acid uptake and synthesis by adipose tissue, and not increased fatty acid oxidation in liver or muscle, were involved in reducing body fat gain. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2008 journal article

Effects of feeding l-carnitine to gilts through day 70 of gestation on litter traits and the expression of insulin-like growth factor system components and l-carnitine concentration in foetal tissues

Journal of Animal Physiology and Animal Nutrition, 92(6), 660–667.

By: K. Brown*, R. Goodband*, M. Tokach*, S. Dritz*, J. Nelssen*, J. Minton*, J. Higgins*, X. Lin n ...

Contributors: K. Brown*, R. Goodband*, M. Tokach*, S. Dritz*, J. Nelssen*, J. Minton*, J. Higgins*, X. Lin n ...

author keywords: foetus; gestation; gilts; l-carnitine; messenger RNA
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Carnitine / administration & dosage; Dietary Supplements; Female; Fetal Development / drug effects; Fetal Development / physiology; Gestational Age; Insulin-Like Growth Factor I / metabolism; Liver / metabolism; Muscle, Skeletal / metabolism; Pregnancy; Pregnancy, Animal / blood; Pregnancy, Animal / metabolism; RNA, Messenger / metabolism; Random Allocation; Somatomedins / metabolism; Swine / blood; Swine / growth & development; Swine / metabolism; Swine / physiology
TL;DR: It was shown that L-carnitine had beneficial effects on the average foetal weight at day 70 of gestation, associated with changes in thefoetal IGF system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2008 journal article

Enrichment of Intestinal Mucosal Phospholipids with Arachidonic and Eicosapentaenoic Acids Fed to Suckling Piglets Is Dose and Time Dependent

The Journal of Nutrition, 138(11), 2164–2171.

By: H. Hess n, B. Corl n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n, J. Odle n

Contributors: H. Hess n, B. Corl n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n, J. Odle n

MeSH headings : Animals; Arachidonic Acid / administration & dosage; Arachidonic Acid / pharmacology; Diet; Dose-Response Relationship, Drug; Drug Administration Schedule; Eicosapentaenoic Acid / administration & dosage; Eicosapentaenoic Acid / pharmacology; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Lactase / metabolism; Swine
TL;DR: D doses demonstrate a dose-dependent response of intestinal mucosal phospholipid ARA concentration to dietary ARA with nearly full enrichment attained within 8 d of feeding formula containing ARA and that supra-physiologic supplementation of ARA is not detrimental to growth. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2008 journal article

Maternal Dietary L-Carnitine Supplementation Influences Fetal Carnitine Status and Stimulates Carnitine Palmitoyltransferase and Pyruvate Dehydrogenase Complex Activities in Swine

The Journal of Nutrition, 138(12), 2356–2362.

By: L. Xi n, K. Brown*, J. Woodworth*, K. Shim n, B. Johnson* & J. Odle n

Contributors: L. Xi n, K. Brown*, J. Woodworth*, K. Shim n, B. Johnson* & J. Odle n

MeSH headings : Animals; Carnitine / administration & dosage; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Dietary Supplements; Energy Metabolism / drug effects; Female; Fetus / metabolism; Kinetics; Liver / enzymology; Maternal-Fetal Exchange; Myocardium / enzymology; Pregnancy; Pyruvate Dehydrogenase Complex / metabolism; Swine
TL;DR: Carnitine ingestion during pregnancy increases fetal carnitine concentrations and stimulates heart PDHC and liver CPT activity without altering Carnitine K(m). (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Polydextrose enrichment of infant formula elicits prebiotic effects without altering systemic growth and development of suckling piglets.

The FASEB Journal, 22(S2), 724–724.

By: T. Herfel n, S. Jacobi n, X. Lin n, D. Walker*, Z. Jouni* & J. Odle n

TL;DR: Polydextrose shows promise as a prebiotic additive in infant formula to better match the oligosaccharide content of human milk. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID
Added: February 20, 2022

2008 conference paper

Stabilized rice bran improves weaning pig growth performance when fed in an antibiotic-free diet

Presented at the American Dairy Science Society and American Society for Animal Science Annual Meeting.

By: T. Herfel, S. Jacobi, X. Lin & J. Odle

Event: American Dairy Science Society and American Society for Animal Science Annual Meeting

Source: NC State University Libraries
Added: May 5, 2022

2008 journal article

The effects of clofibrate on malonyl‐CoA inhibition of carnitine pamitoyltransferase I (CPT I) and fatty acid oxidation in liver of neonatal pigs

The FASEB Journal, 22(S1).

By: K. Shim n, L. Xi n, T. Herfel n & J. Odle n

TL;DR: The results indicate that the increase in fatty acid oxidation induced by clofibrate is due to both an increase in CPT I activity and a decrease in sensitivity of C PT I to malonyl‐CoA inhibition, suggesting that malony l‐Coa plays an important role in the induction of fatty acid oxidisation by cl ofibrate. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 21, 2022

2008 journal article

Transplacental induction of fatty acid oxidation in newborn pigs by clofibrate

The FASEB Journal, 22(S1).

By: L. Xi n, S. Jacobi n & J. Odle n

TL;DR: It is demonstrated that clofibrate crosses the placental membrane of the sow and enters fetal circulation to induce hepatic fatty acid oxidation by increasing CPT and FAO activities of the newborn. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 21, 2022

2007 chapter

Idiosyncrasies of piglet lipid metabolism and their relationship to postnatal mortality

In J. Wiseman (Ed.), Paradigms in pig science (pp. 187–206). Nottingham University Press.

By: X. Lin, B. Corl & J. Odle

Ed(s): J. Wiseman

Source: NC State University Libraries
Added: May 5, 2022

2007 conference paper

Improving fat utilization by the weanling pig: effects of emulsification, diet physical form and fatty-acid-chain-length on growth performance

Presented at the American Society of Animal Science Annual Meeting, San Antonio, TX.

By: K. Price, L. Xi, E. van Heugten, G. Willis & J. Odle

Event: American Society of Animal Science Annual Meeting at San Antonio, TX

Source: NC State University Libraries
Added: May 5, 2022

2007 journal article

Ontogeny of Carnitine Palmitoyltransferase I Activity, Carnitine-Km, and mRNA Abundance in Pigs throughout Growth and Development

The Journal of Nutrition, 137(4), 898–903.

By: P. Lyvers Peffer n, X. Lin n, S. Jacobi n, L. Gatlin n, J. Woodworth* & J. Odle n

Contributors: P. Peffer n, X. Lin n, S. Jacobi n, L. Gatlin n, J. Woodworth* & J. Odle n

MeSH headings : Aging / metabolism; Animal Feed; Animals; Animals, Newborn; Animals, Suckling / metabolism; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Female; Gene Expression; Kinetics; Lipid Metabolism / physiology; Liver / metabolism; Male; Muscle, Skeletal / metabolism; Osmolar Concentration; RNA, Messenger / metabolism; Swine / growth & development; Swine / metabolism
TL;DR: It is suggested that postnatal increases in CPT I activity during the suckling period are accompanied by increased tissue carnitine, and the lack of hepatic C PT I mRNA induction and low activity reported in both tissues prior to 1 wk of age may limit postnatal lipid utilization during the piglet's transition to extra-uterine life. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2006 speech

Cardiomyocyte Isolation, preparation, properties and applications

Presented at the Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS).

By: X. Lin & J. Odle

Event: Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS)

Source: NC State University Libraries
Added: May 5, 2022

2006 journal article

Effects of maternal dietary L‐carnitine on fetal carnitine status as measured by tissue carnitine accumulation and kinetics of carnitine palmitoyltransferase in fetal pigs

The FASEB Journal, 20(4).

By: L. Xi n, K. Brown*, J. Woodworth*, B. Johnson* & J. Odle n

TL;DR: Carnitine ingestion during pregnancy increases carnitine concentrations in liver and muscle of the fetus, but does not impact CPT kinetics. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2006 journal article

Ontogeny and chain-length specificity of gastrointestinal lipases affect medium-chain triacylglycerol utilization by newborn pigs

Journal of Animal Science, 84(4), 818–825.

By: M. Dicklin*, J. Robinson*, X. Lin n & J. Odle n

author keywords: fat digestion; lipase; medium-chain triacylglycerol; ontogeny; pig
MeSH headings : Animals; Animals, Newborn / metabolism; Colostrum; Lipase / metabolism; Pancreas / enzymology; Swine / growth & development; Swine / metabolism; Triglycerides / metabolism
TL;DR: Pancreatic lipase dominates the preduodenal lipases in the neonatal pig, and greater activity of the gastrointestinal lipases toward tri-C6:0 underlies its increased rate of use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2006 journal article

Prophylactic enrichment of enterocyte phospholipids with polyunsaturated fatty acids fed to suckling piglets

The FASEB Journal, 20(4).

By: H. Hess n, B. Corl, X. Lin, L. Averette Gatlin, O. Phillips, R. Harrell, A. Blikslager, J. Odle

TL;DR: These data demonstrate a dose-dependent response in enterocyte AA concentration to dietary AA and show that supra-physiologic supplementation of AA is not detrimental to growth or desaturase gene expression. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 20, 2022

2005 journal article

Effect of ractopamine feeding level on growth performance and carcass composition

Journal of Animal Science.

By: M. See, T. Armstrong, P. Matzat, B. Belstra, F. McKeith, P. Rincker, L. Xi, J. Odle ...

Source: NC State University Libraries
Added: May 5, 2022

2005 chapter

Hepatic fatty acid oxidation and ketogenesis in young pigs

In D. Burrin & H. Mersmann (Eds.), Biology of Growing Animals (Vol. 3, pp. 219–234).

By: J. Odle*, P. Lyvers-Peffer & X. Lin

Contributors: J. Odle*, P. Lyvers-Peffer & X. Lin

Ed(s): D. Burrin & H. Mersmann

TL;DR: This chapter reviews the developmental aspects of lipid oxidation in young pig and reviews the key regulatory enzymes previously elucidated in rodents, with inclusion of the limited knowledge available in pigs. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 19, 2019

2005 journal article

Hepatic β-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 288(6), R1518–R1524.

By: P. Peffer n, X. Lin n & J. Odle n

Contributors: P. Peffer n, X. Lin n & J. Odle n

author keywords: acyl-CoA oxidase; fatty acid oxidase; malonyl-CoA; peroxisome; peroxisome proliferator; activated receptor
MeSH headings : Adrenergic beta-Agonists / pharmacology; Animals; Animals, Newborn / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Clofibric Acid / pharmacology; DNA Primers; DNA, Complementary / biosynthesis; DNA, Complementary / genetics; Diet; Glucose / metabolism; Hypolipidemic Agents / pharmacology; Indicators and Reagents; Isoproterenol / pharmacology; Liver / metabolism; Mitochondria, Liver / enzymology; Mitochondria, Liver / metabolism; Oxidation-Reduction; Palmitic Acids / metabolism; Peroxisomes / metabolism; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction; Swine; Triglycerides / pharmacology
TL;DR: A suckling piglet model was used to study nutritional and pharmacologic means of stimulating hepatic fatty acid β-oxidation and its applications in nutrition and medicine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2005 journal article

Ontogeny and kinetics of carnitine palmitoyltransferase in liver and skeletal muscle of the domestic felid ()

The Journal of Nutritional Biochemistry, 16(6), 331–338.

By: X. Lin n, R. House n & J. Odle n

Contributors: X. Lin n, R. House n & J. Odle n

author keywords: fatty acid oxidation; feline development; lipid metabolism; cats; CPT
MeSH headings : Animals; Carnitine / analogs & derivatives; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / biosynthesis; Carnitine O-Palmitoyltransferase / metabolism; Cats / growth & development; Cats / metabolism; Kinetics; Liver / enzymology; Liver / growth & development; Muscle, Skeletal / enzymology; Muscle, Skeletal / growth & development
TL;DR: It is concluded that postnatal increases in CPT activity support increased capacity for fatty acid oxidation in the developing felid and that dietary carnitine may be required to maximize enzyme activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2004 speech

Fatty acid oxidation in neonatal pigs

Presented at the Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS).

By: X. Lin & J. Odle

Event: Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS)

Source: NC State University Libraries
Added: May 5, 2022

2004 journal article

Ontogeny of carnitine biosynthesis in pigs, inferred from gamma-butyrobetaine hydroxylase activity

FASEB Journal.

By: X. Lin, P. Lyvers Peffer, J. Woodworth & J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2004 journal article

Ontogeny of mitochondrial carnitine palmitoyltransferase I in porcine liver and skeletal muscle

Journal of Animal Science, 82(Suppl. 1), 20.

By: P. Lyvers-Peffer, X. Lin, L. Averette Gatlin, J. Woodworth & J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2004 journal article

Refining in vitro digestibility assays: Fractionation of digestible and indigestible peptides

Journal of Animal Science, 82(6), 1669–1677.

MeSH headings : Amino Acids / metabolism; Animal Feed; Animals; Chromatography, Gel / veterinary; Dietary Proteins / metabolism; Digestion; Homoarginine / metabolism; Ileum / metabolism; In Vitro Techniques; Male; Particle Size; Random Allocation; Solubility; Swine / metabolism
TL;DR: In vitro digestibility assays should exhaustively digest proteins to mimic in vivo digestibility, and an in vitro assay based on these principles lacked precision for highly water-soluble AA, and underestimated digestibility for other AA. (via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2003 journal article

Changes in Kinetics of Carnitine Palmitoyltransferase in Liver and Skeletal Muscle of Dogs (Canis familiaris) throughout Growth and Development

The Journal of Nutrition, 133(4), 1113–1119.

By: X. Lin n & J. Odle n

author keywords: canine; carnitine; carnitine palmitoyltransferase; fatty acid oxidation; ontogeny
MeSH headings : Animals; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Dogs; Female; Kinetics; Liver / enzymology; Liver / growth & development; Liver / metabolism; Muscle, Skeletal / growth & development; Muscle, Skeletal / metabolism; Pregnancy
TL;DR: It is inferred that fatty acid oxidation capacity increases rapidly after birth in the canine, after ontogenic increases in CPT activity and that increased dietary carnitine may improve fatty acid oxidative capacity in developing dogs. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2003 journal article

Conjugated linoleic acid reduces total body fat while not affecting the metabolism of essential fatty acids in the liver, brain or skeletal muscle of neonatal pigs

FASEB Journal, 17(5).

By: S. Mathews, W. Oliver, X. Lin, J. Odle & R. Harrell

Source: NC State University Libraries
Added: May 5, 2022

2003 journal article

Conjugated linoleic acid reduces total body fat, while not affecting the metabolism of essential fatty acids in the liver, brain or skeletal muscle of neonatal pigs

FASEB Journal, 17(4), A752.

By: W. Oliver, X. Lin, J. Odle & R. Harrell

Source: NC State University Libraries
Added: May 5, 2022

2003 journal article

Dietary conjugated kinoleic acid (CLA) reduces long-chain polyunsaturated fatty acid (LCPUFA) biosynthesis in brain and liver tissues of neonatal pigs

FASEB Journal, 16, A223.

By: J. Bo, X. Lin, S. Mathews Oliver, R. Harrell & J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2003 journal article

Influence of dietary cobalt source and concentration on performance, vitamin B12 status, and ruminal and plasma metabolites in growing and finishing steers

Journal of Animal Science, 81(12), 3151–3159.

By: M. Tiffany n, J. Spears n, L. Xi n & J. Horton

MeSH headings : Animals; Biological Availability; Cattle / growth & development; Cattle / metabolism; Cobalt / administration & dosage; Cobalt / pharmacokinetics; Dose-Response Relationship, Drug; Male; Nutritional Requirements; Nutritional Status; Rumen / metabolism; Vitamin B 12 / blood; Vitamin B 12 / metabolism; Weight Gain
TL;DR: The results suggest that finishing steers require approximately 0.15 mg Co/kg of DM, whereas other carcass characteristics were not affected by dietary Co, and average daily gain and feed efficiency did not differ among Co-supplemented steers. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2002 journal article

Conjugated Linoleic Acid in Combination with Supplemental Dietary Fat Alters Pork Fat Quality

The Journal of Nutrition, 132(10), 3105–3112.

By: L. Gatlin n, M. See n, D. Larick n, X. Lin n & J. Odle n

author keywords: conjugated linoleic acid; fatty acid composition; pork; supplemental fat; swine
MeSH headings : Adipose Tissue / anatomy & histology; Adipose Tissue / chemistry; Adipose Tissue / metabolism; Animal Feed / standards; Animals; Body Composition / drug effects; Dietary Fats / administration & dosage; Dietary Supplements; Fatty Acids / analysis; Female; Isomerism; Linoleic Acid / administration & dosage; Linoleic Acid / metabolism; Meat / standards; Muscle, Skeletal / anatomy & histology; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism; Random Allocation; Swine / genetics; Swine / growth & development
TL;DR: CLA enrichment of pork products may be enhanced when combined with additional supplemental dietary fat, and together with tallow can be used to increase the saturated fatty acid content of pork. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2002 journal article

Conjugated lenoleic acid increase oleic acid oxidation in 3T3-L1 preadipocytes

FASEB Journal, 16(5), A1016.

By: M. Evens, X. Lin, J. Odle & M. McIntosh

Source: NC State University Libraries
Added: May 5, 2022

2002 journal article

Essential fatty acid deficiency in piglets decreases b-oxidation of 14C linoleate and 14C palmitate in both liver and brain tissues

FASEB Journal, 16(4), A233.

By: S. Mathews, W. Oliver, X. Lin, O. Phillips, J. Brown, J. Odle, R. Harrell

Source: NC State University Libraries
Added: May 5, 2022

2002 journal article

Induction of post-natal carnitine palmitoyltransferase activity and hepatic b-oxidation in piglets

FASEB Journal, 16(4), A632.

By: P. Lvvers-Peffer, X. Lin, R. Harrell & J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2002 journal article

Medium-Chain Fatty Acids but Not L-Carnitine Accelerate the Kinetics of [14C]Triacylglycerol Utilization by Colostrum-Deprived Newborn Pigs

The Journal of Nutrition, 132(7), 1989–1994.

By: K. Heo n, X. Lin n, I. Han n & J. Odle*

Contributors: K. Heo n, X. Lin n, I. Han n & J. Odle*

author keywords: pigs; neonate; carnitine; triglycerldes; fatty acid utilization
MeSH headings : Animals; Animals, Newborn / metabolism; Carbon Radioisotopes; Carnitine / pharmacology; Colostrum / physiology; Fatty Acids / chemistry; Fatty Acids / pharmacology; Intestinal Mucosa / metabolism; Kinetics; Oxidation-Reduction / drug effects; Swine; Triglycerides / metabolism
TL;DR: Findings quantify the accelerated oxidation of medium-chain vs. long-chain triglycerides, but fail to support a need for supplemental carnitine to maximize fat oxidation in colostrum-deprived piglets. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2002 journal article

Trans-10, Cis-12 Conjugated Linoleic Acid Increases Fatty Acid Oxidation in 3T3-L1 Preadipocytes

The Journal of Nutrition, 132(3), 450–455.

By: M. Evans n, X. Lin*, J. Odle* & M. McIntosh*

author keywords: conjugated linoleic acid; preadipocytes; glucose and fatty acid oxidation; glucose and fatty acid incorporation; lipolysis
MeSH headings : 3T3 Cells; Adipocytes / drug effects; Adipocytes / metabolism; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Esterification; Fatty Acids / metabolism; Glucose / metabolism; Linoleic Acid / chemistry; Linoleic Acid / pharmacology; Lipid Metabolism; Mice; Oleic Acid / metabolism; Oxidation-Reduction; Stem Cells / drug effects; Stem Cells / metabolism; Stereoisomerism
TL;DR: The TG-lowering actions of trans-10, cis-12 CLA in cultures of 3T3-L1 preadipocytes may be via increased fatty acid oxidation, which exceeded its stimulatory effects on glucose and oleic acid incorporation into lipid. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2001 journal article

Determination of Carnitine Renal Threshold and Effect of Medium-Chain Triglycerides on Carnitine Profiles in Newborn Pigs

Asian-Australasian Journal of Animal Sciences, 14(2), 237–242.

By: K. Heo*, J. Odle*, X. Lin*, T. Kempen & I. Han

author keywords: carnitine; renal threshold; medium-chain triglycerides; newborn pigs; acyl intoxication
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2001 report

Effect of L-carnitine and medium-chain triglyceride on plasma and urinary in newborn piglets

[Swine Reports].

By: K. Heo, J. Odle, X. Lin, T. van Kempen & I. Han

Source: NC State University Libraries
Added: May 5, 2022

2001 journal article

Effects of long_chain polyunsaturated fatty acids (LCPUFA) on body composition and tissue accretion in the neonatal pig

Journal of Animal Science, 79(Suppl. 1), 398.

By: S. Mathews, R. Harrell, W. Oliver, J. Brown, O. Phillips, X. Lin, J. Odle, D. Diersen-Schade

Source: NC State University Libraries
Added: May 5, 2022

2001 report

Kinetics of carnitine palmitoyltrasferase I in liver and skeletal muscle of young pigs

[Swine Reports].

By: K. Heo, X. Lin, J. Odle & I. Han

Source: NC State University Libraries
Added: May 5, 2022

2000 journal article

Dietary copper effects on lipid metabolism and circulating catecholamine concentrations in finishing steers

Journal of Animal Science, 78(10), 2737–2744.

By: T. Engle n, J. Spears n, L. & F. Edens n

MeSH headings : Adipose Tissue / metabolism; Animal Feed; Animals; Catecholamines / blood; Cattle / metabolism; Copper / pharmacology; Diet; Dietary Supplements; Fatty Acids, Nonesterified / metabolism; Lipid Metabolism; Liver / metabolism; Male; Weight Gain
TL;DR: Results indicate that Cu addition to a finishing diet containing 5 mg Cu/kg DM alters lipid metabolism in steers, and the reduction in backfat depth may be due to copper altering catecholamine metabolism in Steers. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2000 conference paper

Effect of L-carnitine and emulsified trioctanolyglycerol on kinetics of plasma carnitine and urinary carnitine excretion in colostrum-deprived newborn piglets

Proceedings of the 2000 International Symposium on Recent Advances in Animal Nutrition, 445 447.

By: K. Heo, J. Odle, X. Lin, T. van Kempen & I. Han

Event: International Symposium on Recent Advances in Animal Nutrition at Seoul National University, Seoul, Korea

Source: NC State University Libraries
Added: May 5, 2022

2000 journal article

Kinetics of Carnitine Palmitoyltransferase-I Are Altered by Dietary Variables and Suggest a Metabolic Need for Supplemental Carnitine in Young Pigs

The Journal of Nutrition, 130(10), 2467–2470.

By: K. Heo n, X. Lin n, J. Odle n & I. Han*

author keywords: pigs; carnitine; protein; carnitine palmitoyltransferase-I; liver; muscle
MeSH headings : Animals; Carnitine / administration & dosage; Carnitine / analogs & derivatives; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Diet; Dietary Supplements; Kinetics; Liver / metabolism; Mitochondria / enzymology; Mitochondria, Liver / enzymology; Muscle, Skeletal / metabolism; Muscle, Skeletal / ultrastructure; Soybean Oil; Soybeans; Swine / physiology; Zea mays
TL;DR: It is inferred that alteration of tissue carnitine concentrations via dietary supplementation could modulate CPT-I activity in young pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2000 journal article

Kinetics of carnitine palmitoyltransferase in frozen feline liver

FASEB Journal, 14, A208.

By: X. Lin, J. Odle, R. Buddington & A. Lepine

Source: NC State University Libraries
Added: May 5, 2022

2000 journal article

The effect of glucagons and insulin on b-oxidation of 1-14C-palmitate by piglet hepatocyted in primary culture

Journal of Animal Science.

By: G. Mastey, X. Lin & J. Odle

Source: NC State University Libraries
Added: May 5, 2022

2000 journal article

The role of carnitine and betaine in lean growth modulation of swine

Asian-Australasian Journal of Animal Sciences, 13(2000), 386–395.

By: J. Odle, K. Heo & X. Lin

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Acetyl-Coenzyme A carboxylase (ACC) activity in the liver and adipose tissue during development of the canine

FASEB Journal, 13(5), A903.

By: X. Lin, J. Odle, R. Buddington & A. Lepine

Source: NC State University Libraries
Added: May 5, 2022

1999 journal article

Carnitine palmitoyltransferase I activity and carnitine concentration in liver and skeletal muscle of 20 kg pigs

FASEB Journal, 13(5), A908.

By: J. Odle, K. Heo, X. Lin & I. Han

Source: NC State University Libraries
Added: May 5, 2022

1999 conference paper

The effect of 5-aminoimidaole-4-caboxamide ribonucleoside (AICAR) on hepatic fatty acid oxidation in neonatal piglets

10th Annual institute of Nutrition Research Symposium Proceedings, P16.

By: X. Lin, G. Matsey, K. Heo & J. Odle

Event: Institute of Nutrition at University of North Carolina

Source: NC State University Libraries
Added: May 5, 2022

1998 conference paper

Effect of L-alanyl-glutamine on rotaviral enteritis of neonatal piglets

Annual Research Symposium presented at the Institute of Nutrition, University of North Carolina.

By: C. Mareskes, J. Odle, X. Lin, G. Gomez & B. Black

Event: Institute of Nutrition at University of North Carolina

Source: NC State University Libraries
Added: May 5, 2022

1998 journal article

Ontogeny and kinetics of carnitine acyltransferase activity in the canine

FASEB Journal.

By: X. Lin, J. Odle, R. Buddington & A. Lepine

Source: NC State University Libraries
Added: May 5, 2022

1997 conference paper

Effects of glucagon on piglet hepatocytes in primary culture

Annual Research Symposium presented at the The Institute of Nutrition, University of North Carolina.

By: G. Matsey, X. Lin & J. Odle

Event: The Institute of Nutrition at University of North Carolina

Source: NC State University Libraries
Added: May 5, 2022

1997 journal article

Hepatic fatty acid metabolism in pigs and rats: major differences in endproducts, O2 uptake, and beta-oxidation

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 272(5), R1641–R1646.

By: S. Adams*, X. Lin*, X. Yu*, J. Odle* & J. Drackley*

author keywords: acetate; ketone bodies; metabolic rate; piglets
MeSH headings : Animals; Animals, Newborn; Body Weight; Fasting; Fatty Acids / metabolism; Liver / metabolism; Oxidation-Reduction; Oxygen Consumption; Rats; Species Specificity; Swine
TL;DR: Data concur with the hypotheses that comparatively low hepatic beta-oxidative flux in piglets is partially related to a smaller metabolic rate and that substantial acetogenesis occurs intramitochondrially in both pigs and rats. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

1997 journal article

Response of Hepatic Mitochondrial and Peroxisomal β-Oxidation to Increasing Palmitate Concentrations in Piglets

Neonatology, 72(5), 284–292.

By: X. Yu, J. Drackley*, J. Odle* & X. Lin*