Xiangdong Wang

Works (7)

Updated: July 5th, 2023 15:56

2015 journal article

Single cell sequencing and systems immunology preface

Single Cell Sequencing and Systems Immunology, V-.

By: X. Wang

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development

CELL CYCLE, 11(2), 335–342.

By: X. Wang n, C. Sistrunk  n, P. Marval*, Y. Kim* & M. Rodriguez-Puebla n

author keywords: cell cycle; D-type cyclins; skin; carcinogenesis; epidermis
MeSH headings : 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell / chemically induced; Carcinoma, Squamous Cell / metabolism; Carcinoma, Squamous Cell / pathology; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1 / genetics; Cyclin D1 / metabolism; Cyclin D2 / metabolism; Cyclin D3 / genetics; Cyclin D3 / metabolism; Gene Expression Regulation; Mice; Mice, Transgenic; Oncogene Protein p21(ras) / genetics; Papilloma / chemically induced; Papilloma / metabolism; Papilloma / pathology; Skin / pathology; Skin Neoplasms / chemically induced; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Tumor Burden
TL;DR: Modulation of the levels of particular members of the D-type cyclin family could be useful to inhibit tumor development and, in particular, ras-mediated tumorigenesis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2008 journal article

Epithelial brush border proteomics and associated dysfunction.

404nOtfound, 1, 27–33.

By: X. Wang & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2008 review

Role of airway epithelial cells in development of asthma and allergic rhinitis

[Review of ]. RESPIRATORY MEDICINE, 102(7), 949–955.

By: Y. Wang *, C. Bai *, K. Li *, K. Adler n & X. Wang*

author keywords: airway hyper-responsiveness; allergic cascade; airway epithelium; inflammation; rhinitis
MeSH headings : Asthma / etiology; Asthma / immunology; Bronchi / immunology; Bronchi / pathology; Cytokines / metabolism; Epithelial Cells / physiology; Humans; Inflammation Mediators / metabolism; Mucus / immunology; Rhinitis / etiology; Rhinitis / immunology; Th2 Cells / immunology; Toll-Like Receptors / metabolism
TL;DR: It is hypothesized that airway epithelial cells may play as both inflammatory initiator and immuno-pathological feedback regulation between allergic rhinitis and asthma via release of systemic inflammatory mediators. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Proteomics in the study of organ dysfunction

Expert Review of Proteomics, 4(1), 1–3.

By: X. Wang

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Role of airway epithelial dysfunction in development of acute lung injury and acute respiratory distress syndrome.

404nOtfound, 1, 149–155.

By: X. Wang*, K. Adler n, J. Erjefalt * & C. Bai *

TL;DR: It is hypothesized that airway epithelial cells may contribute to ALI/ARDS via Toll-like receptor-involved mediators, reactive oxygen species-involved reactions and an imbalance between protease and antiprotease activation. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2006 review

Epithelial proteomics in multiple organs and tissues: Similarities and variations between cells, organs, and diseases

[Review of ]. JOURNAL OF PROTEOME RESEARCH, 5(4), 743–755.

By: H. Zhao *, K. Adler*, C. Bai *, F. Tang* & X. Wang*

author keywords: epithelial cells; proteomics; differentiation; tumorigenesis; cancer; biomarkers
MeSH headings : Biomarkers, Tumor / analysis; Cell Differentiation; Cell Line, Tumor; Epithelial Cells / chemistry; Epithelial Cells / pathology; Epithelial Cells / physiology; Forecasting; Genetic Variation; Genomics; Humans; Models, Biological; Neoplasm Proteins / analysis; Neoplasms / etiology; Neoplasms / genetics; Neoplasms / pathology; Proteome / analysis; Proteomics; Sensitivity and Specificity; Severity of Illness Index
TL;DR: It is found that most of disease-associated investigation of epithelial proteomics has been focused on epithelial-origin cancer, and there is a significant gap between acute and chronic organ injury, inflammation, and multiple organ dysfunction. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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