Works (48)

Updated: July 20th, 2023 21:16

2023 journal article

MicroRNA and mRNA sequencing analyses reveal key hepatic metabolic and signaling pathways responsive to maternal undernutrition in full-term fetal pigs

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 116.

By: F. Wang n, C. Man n, X. Wang n , J. Odle n , C. Maltecca n  & . Lin  n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Maternal undernutrition; RNA sequencing; mRNA-miRNA correlation analysis; Ingenuity Pathways Analysis (IPA); Oxidative phosphorylation
MeSH headings : Pregnancy; Female; Animals; Swine; RNA, Messenger / metabolism; Fetus / metabolism; Liver / metabolism; Signal Transduction; Malnutrition / metabolism
Sources: Web Of Science, ORCID
Added: March 4, 2023

2023 article

Uterine histotroph and conceptus development: III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway

Liu, B., Paudel, S., Flowers, W. L., Piedrahita, J. A., & Wang, X. (2023, April 10). AMINO ACIDS, Vol. 4.

By: B. Liu n , S. Paudel n, W. Flowers n, J. Piedrahita n & X. Wang n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Adrenomedullin; Trophectoderm cells; MTOR; Pigs; Implantation
MeSH headings : Pregnancy; Female; Swine; Animals; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Adrenomedullin / pharmacology; Signal Transduction; TOR Serine-Threonine Kinases / genetics; TOR Serine-Threonine Kinases / metabolism; Cell Proliferation; Sirolimus / pharmacology
Sources: Web Of Science, ORCID
Added: April 24, 2023

2022 journal article

Prioritize biologically relevant ions for data-independent acquisition (BRI-DIA) in LC-MS/MS-based lipidomics analysis

METABOLOMICS, 18(8).

By: L. Duan n, G. Scheidemantle n, M. Lodge n, M. Cummings n, E. Pham n, X. Wang n , A. Kennedy n , X. Liu n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Cardiolipins; Chromatography, Liquid / methods; Ions; Lipidomics; Metabolomics; Mice; Reproducibility of Results; Tandem Mass Spectrometry / methods
Sources: Web Of Science, ORCID
Added: July 26, 2022

2022 journal article

Uterine-specific SIRT1 deficiency confers premature uterine aging and impairs invasion and spacing of blastocyst, and stromal cell decidualization, in mice

MOLECULAR HUMAN REPRODUCTION, 28(7).

By: M. Cummings n, H. Yu*, S. Paudel n, G. Hu *, X. Li *, M. Hemberger *, X. Wang n 

co-author countries: Canada πŸ‡¨πŸ‡¦ United States of America πŸ‡ΊπŸ‡Έ
author keywords: SIRT1; implantation; stromal cell decidualization; pregnancy; Sirtuin 1; progesterone receptor signaling
MeSH headings : Aging; Animals; Blastocyst; Decidua / metabolism; Embryo Implantation / physiology; Female; Hedgehog Proteins / metabolism; Mice; Pregnancy; Sirtuin 1 / genetics; Sirtuin 1 / metabolism; Stromal Cells / metabolism; Uterus / metabolism
Sources: Web Of Science, ORCID
Added: July 11, 2022

2021 article

Amino Acids in Cell Signaling: Regulation and Function

AMINO ACIDS IN NUTRITION AND HEALTH: AMINO ACIDS IN GENE EXPRESSION, METABOLIC REGULATION, AND EXERCISING PERFORMANCE, Vol. 1332, pp. 17–33.

By: S. Paudel n, G. Wu * & X. Wang n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Functional amino acids; Transceptor; Sensor; mTORC1; AMPK; MAPK
MeSH headings : Amino Acids; Animals; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1 / genetics; Signal Transduction
Sources: Web Of Science, ORCID
Added: October 26, 2021

2021 journal article

Temporal and spatial expression of adrenomedullin and its receptors in the porcine uterus and peri-implantation conceptuses

BIOLOGY OF REPRODUCTION, 105(4), 876–891.

By: S. Paudel n, B. Liu n , M. Cummings n, K. Quinn*, F. Bazer*, K. Caron *, X. Wang n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: adrenomedullin; conceptus; uterine fluid; uterus; pigs
MeSH headings : Adrenomedullin / genetics; Adrenomedullin / metabolism; Animals; Embryo, Mammalian / metabolism; Female; Receptors, Adrenomedullin / genetics; Receptors, Adrenomedullin / immunology; Spatio-Temporal Analysis; Sus scrofa / embryology; Sus scrofa / genetics; Uterus / metabolism
Sources: Web Of Science, ORCID
Added: November 15, 2021

2019 article

ENDOMETRIAL EPITHELIAL FOXO1 DIRECTLY MODULATES SIGNALING PATHWAYS NECESSARY FOR UTERINE RECEPTIVITY.

Moustafa, S. M., Young, S. L., Wang, T., Wu, S., Li, R., Wang, X., … Demayo, F. (2019, September). FERTILITY AND STERILITY, Vol. 112, pp. E314–E315.

By: S. Moustafa *, S. Young *, T. Wang *, S. Wu *, R. Li *, X. Wang n , T. Spencer*, F. Demayo*

co-author countries: Netherlands πŸ‡³πŸ‡± United States of America πŸ‡ΊπŸ‡Έ
Sources: Web Of Science, ORCID
Added: October 28, 2019

2018 journal article

FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation

PLOS GENETICS, 14(11).

By: Y. Vasquez*, X. Wang n , M. Wetendorf*, H. Franco*, Q. Mo *, T. Wang *, R. Lanz *, S. Young * ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Cell Nucleus / metabolism; Cell Polarity / genetics; Cell Polarity / physiology; Decidua / physiology; Embryo Implantation / genetics; Embryo Implantation / physiology; Endometrium / cytology; Endometrium / metabolism; Female; Forkhead Box Protein O1 / deficiency; Forkhead Box Protein O1 / genetics; Forkhead Box Protein O1 / metabolism; Gene Expression Profiling; Humans; Mice; Mice, Knockout; Pregnancy; Receptors, Progesterone / deficiency; Receptors, Progesterone / genetics; Receptors, Progesterone / metabolism; Signal Transduction
Sources: Web Of Science, ORCID
Added: December 31, 2018

2018 journal article

Functional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep

Journal of Animal Science and Biotechnology, 9(1).

By: Y. Lenis, G. Johnson, X. Wang* , W. Tang, K. Dunlap, M. Satterfield, G. Wu, T. Hansen, F. Bazer

author keywords: Agmatine; Arginine; Interferon tau; Polyamines; Trophectoderm cells
Sources: Crossref, ORCID
Added: May 4, 2020

2018 journal article

Innate differences and colostrum-induced alterations of jejunal mucosal proteins in piglets with intra-uterine growth restriction

British Journal of Nutrition, 119(7), 734–747.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Jejunum; Colostrum; Porcine neonates; Intra-uterine growth restriction; Proteomics
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blood Glucose; Colostrum; Energy Metabolism; Female; Fetal Growth Retardation / immunology; Fetal Growth Retardation / metabolism; Fetal Growth Retardation / veterinary; Gene Expression Regulation / drug effects; Glucose / metabolism; Intestinal Mucosa / metabolism; Jejunum / drug effects; Jejunum / metabolism; Pregnancy; Proteomics; Swine; Swine Diseases / immunology; Swine Diseases / metabolism; Transcriptome
Sources: Crossref, ORCID
Added: May 4, 2020

2018 journal article

SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh

NATURE COMMUNICATIONS, 9.

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / physiology; Endometrium / metabolism; Female; GATA2 Transcription Factor / genetics; GATA2 Transcription Factor / metabolism; HMGB Proteins / genetics; HMGB Proteins / metabolism; Hedgehog Proteins / genetics; Hedgehog Proteins / metabolism; Hepatocyte Nuclear Factor 3-beta / genetics; Hepatocyte Nuclear Factor 3-beta / metabolism; Leukemia Inhibitory Factor / genetics; Leukemia Inhibitory Factor / metabolism; Mice; SOXF Transcription Factors / genetics; SOXF Transcription Factors / metabolism; Transcriptome / genetics; Uterus / metabolism
Sources: Web Of Science, ORCID
Added: November 5, 2018

2017 journal article

Decidualisation and placentation defects are a major cause of age-related reproductive decline

Nature Communications, 8(1).

By: L. Woods *, V. Perez-Garcia*, J. Kieckbusch*, X. Wang* , F. DeMayo*, F. Colucci *, M. Hemberger *

co-author countries: United Kingdom of Great Britain and Northern Ireland πŸ‡¬πŸ‡§ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Age Factors; Aging / genetics; Aging / physiology; Animals; Cells, Cultured; Decidua / metabolism; Decidua / physiopathology; Embryonic Development / genetics; Embryonic Development / physiology; Female; Gene Expression Profiling / methods; Humans; Male; Maternal Age; Mice, Inbred C57BL; Placenta / metabolism; Placenta / physiopathology; Placentation / genetics; Pregnancy; Pregnancy Complications / genetics; Pregnancy Complications / physiopathology; Reproduction / genetics; Reproduction / physiology; Uterus / metabolism; Uterus / physiopathology
Sources: Crossref, ORCID
Added: May 4, 2020

2017 journal article

Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment†

Biology of Reproduction, 96(2), 313–326.

By: M. Wetendorf*, S. Wu *, X. Wang* , C. Creighton *, T. Wang *, R. Lanz *, L. Blok*, S. Tsai* ...

co-author countries: Netherlands πŸ‡³πŸ‡± United States of America πŸ‡ΊπŸ‡Έ
author keywords: progesterone receptor; implantation; uterine receptivity; progesterone signaling; mouse models
MeSH headings : Alleles; Animals; Cloning, Molecular; Down-Regulation; Embryo Implantation; Endometrium; Female; Gene Expression Regulation / physiology; Hedgehog Proteins / genetics; Hedgehog Proteins / metabolism; Male; Mice, Transgenic; Progesterone / metabolism; Receptors, OSM-LIF / genetics; Receptors, OSM-LIF / metabolism; Receptors, Progesterone / genetics; Receptors, Progesterone / metabolism; Wnt Proteins / genetics; Wnt Proteins / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2017 chapter

Delivery of Morpholino Antisense Oligonucleotides to a Developing Ovine Conceptus via Luminal Injection into a Ligated Uterine Horn

In Morpholino Oligomers (pp. 241–250).

By: X. Wang*  & K. Dunlap*

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Ovine; Conceptus; Peri-implantation; Uterine ligation; Morpholino antisense oligonucleotide; Endo-Porter
MeSH headings : Animals; Embryonic Development / genetics; Female; Gene Transfer Techniques; Morpholinos / administration & dosage; Morpholinos / genetics; Oligonucleotides, Antisense; Peptides; Uterus
Sources: Crossref, ORCID
Added: May 4, 2020

2017 journal article

Hormone dependent uterine epithelial-stromal communication for pregnancy support

Placenta, 60, S20–S26.

By: X. Wang* , S. Wu * & F. DeMayo *

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Progesterone; Pregnancy; Uterine receptivity
MeSH headings : Animals; Biomedical Research / methods; Biomedical Research / trends; Cell Communication; Cell Transdifferentiation; Embryo Implantation; Endometrium / cytology; Endometrium / physiology; Estrogens / metabolism; Estrogens / physiology; Female; Humans; Ovary / metabolism; Ovary / physiology; Pregnancy; Progesterone / metabolism; Progesterone / physiology; Stromal Cells / cytology; Stromal Cells / physiology; Uterus / cytology; Uterus / physiology
Sources: Crossref, ORCID
Added: May 4, 2020

2016 journal article

Effects of agmatine on secretion of interferon tau and catecholamines and expression of genes related to production of polyamines by ovine trophectoderm cells

Amino Acids, 48(10), 2389–2399.

By: Y. Lenis*, X. Wang* , W. Tang *, G. Wu * & F. Bazer

co-author countries: Colombia πŸ‡¨πŸ‡΄ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Arginine; Agmatine; Polyamines; Trophectoderm cells; Interferon tau
MeSH headings : Agmatine / pharmacology; Animals; Biogenic Polyamines / biosynthesis; Catecholamines / metabolism; Cells, Cultured; Female; Gene Expression Regulation / drug effects; Interferon Type I / metabolism; Pregnancy Proteins / metabolism; Sheep; Trophoblasts / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2016 journal article

Functional Roles of Fructose: Crosstalk between O-Linked Glycosylation and Phosphorylation of Akt-TSC2-MTOR Cell Signaling Cascade in Ovine Trophectoderm Cells

Biology of Reproduction, 95(5), 102–102.

By: X. Wang* , D. Li *, G. Wu * & F. Bazer*

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: fructose; O-linked glycosylation; phosphorylation; trophoblast
Sources: Crossref, ORCID
Added: May 4, 2020

2016 journal article

Uterine Histotroph and Conceptus Development. II. Arginine and Secreted Phosphoprotein 1 Cooperatively Stimulate Migration and Adhesion of Ovine Trophectoderm Cells via Focal Adhesion-MTORC2 Mediated Cytoskeleton Reorganization

Biology of Reproduction, 95(3), 71–71.

By: X. Wang* , G. Johnson*, R. Burghardt *, G. Wu * & F. Bazer

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
Sources: Crossref, ORCID
Added: May 4, 2020

2016 chapter

mTOR: The Master Regulator of Conceptus Development in Response to Uterine Histotroph During Pregnancy in Ungulates

In K. Maiese (Ed.), Molecules to Medicine with mTOR: Translating Critical Pathways Into Novel Therapeutic Strategies (pp. 23–35).

By: X. Wang* , G. Wu * & F. Bazer

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Ed(s): K. Maiese

Sources: NC State University Libraries, ORCID
Added: April 4, 2021

2015 journal article

Exosomes, endogenous retroviruses and toll-like receptors: pregnancy recognition in ewes

REPRODUCTION, 149(3), 281–291.

By: I. Ruiz-GonzΓ‘lez*, J. Xu*, X. Wang* , R. Burghardt *, K. Dunlap* & F. Bazer*

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Cytokines / metabolism; Embryo Implantation / physiology; Endogenous Retroviruses / metabolism; Endometrium / metabolism; Exosomes / metabolism; Female; Pregnancy; Pregnancy, Animal / physiology; Sheep / physiology; Signal Transduction / physiology; Toll-Like Receptors / genetics; Toll-Like Receptors / metabolism; Uterus / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2015 journal article

Functional Roles of Arginine During the Peri-Implantation Period of Pregnancy. III. Arginine Stimulates Proliferation and Interferon Tau Production by Ovine Trophectoderm Cells via Nitric Oxide and Polyamine-TSC2-MTOR Signaling Pathways

Biology of Reproduction, 92(3).

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: arginine; interferon tau; mechanistic target of rapamycin; trophectoderm; tuberous sclerosis protein 2
MeSH headings : Animals; Arginine / pharmacology; Arginine / physiology; Cell Proliferation / drug effects; Cell Proliferation / physiology; Cells, Cultured; Dose-Response Relationship, Drug; Ectoderm / cytology; Ectoderm / drug effects; Ectoderm / metabolism; Embryo Implantation / physiology; Female; Interferon Type I / metabolism; Models, Animal; Nitric Oxide / metabolism; Phosphorylation; Polyamines / metabolism; Pregnancy; Pregnancy Proteins / metabolism; Pregnancy, Animal / physiology; Putrescine / metabolism; Repressor Proteins / metabolism; Sheep / physiology; Signal Transduction / drug effects; Signal Transduction / physiology; TOR Serine-Threonine Kinases / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2015 journal article

Involvement of TLR7 and TLR8 in conceptus development and establishment of pregnancy in sheep

REPRODUCTION, 149(4), 305–316.

By: I. Ruiz-GonzΓ‘lez, M. Minten, X. Wang* , K. Dunlap & F. Bazer

MeSH headings : Animals; Cells, Cultured; Embryo Implantation / drug effects; Embryo, Mammalian / cytology; Embryo, Mammalian / drug effects; Embryo, Mammalian / metabolism; Embryonic Development / drug effects; Endometrium / cytology; Endometrium / drug effects; Endometrium / metabolism; Estrous Cycle; Female; Fetal Development / drug effects; Immunoenzyme Techniques; Oligonucleotides, Antisense / pharmacology; Pregnancy; RNA, Messenger / genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sheep; Toll-Like Receptor 7 / antagonists & inhibitors; Toll-Like Receptor 7 / metabolism; Toll-Like Receptor 8 / antagonists & inhibitors; Toll-Like Receptor 8 / metabolism; Uterus / cytology; Uterus / drug effects; Uterus / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2015 journal article

Select nutrients and their effects on conceptus development in mammals

Animal Nutrition, 1(3), 85–95.

By: F. Bazer *, X. Wang* , G. Johnson* & G. Wu

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Amino acids; Secreted phosphoprotein 1; Pregnancy; Interferon tau; Conceptus development; Trophectoderm
Sources: Crossref, ORCID
Added: May 4, 2020

2015 journal article

Synthesis of polyamines from L-proline in the porcine placenta and neonatal enterocytes

Amino Acids, 47(8), 1669.

By: G. Wu, F. Bazer, X. Wang , G. Johnson, Y. Hou, Z. Dai, J. Wang, Z. Wu

Source: NC State University Libraries
Added: April 24, 2021

2015 journal article

The many faces of interferon tau

Amino Acids, 47(3), 449–460.

By: F. Bazer*, W. Ying *, X. Wang* , K. Dunlap*, B. Zhou *, G. Johnson*, G. Wu *

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Uterus; Amino acids; Proteins; Pregnancy; Uteroferrin; Interferon tau
MeSH headings : Animals; Arginine / metabolism; Biological Transport, Active / physiology; Embryo, Mammalian / metabolism; Female; Interferon Type I / metabolism; Pregnancy / metabolism; Pregnancy Proteins / metabolism; Ruminants / metabolism; Uterus / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2015 journal article

The many faces of interferon tau at the maternal-conceptus interface

American Journal of Reproductive Immunology, 73(S2), 21.

By: F. Bazer, I. Ruiz-Gonzalez, J. Xu, X. Wang  & K. Dunlap

Source: NC State University Libraries
Added: April 24, 2021

2015 journal article

Uterine Histotroph and Conceptus Development. I. Cooperative Effects of Arginine and Secreted Phosphoprotein 1 on Proliferation of Ovine Trophectoderm Cells via Activation of the PDK1-Akt/PKB-TSC2-MTORC1 Signaling Cascade

Biology of Reproduction, 92(2).

By: X. Wang* , G. Johnson*, R. Burghardt *, G. Wu * & F. Bazer

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: arginine; MTORC1; sheep; SPP1; trophectoderm
MeSH headings : Animals; Arginine / pharmacology; Cell Line; Cell Proliferation / drug effects; Cell Proliferation / physiology; Embryonic Development / drug effects; Female; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes / metabolism; Osteopontin / pharmacology; Pregnancy; Protein Serine-Threonine Kinases / metabolism; Proto-Oncogene Proteins c-akt / metabolism; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sheep; Signal Transduction / drug effects; Signal Transduction / physiology; TOR Serine-Threonine Kinases / metabolism; Uterus / drug effects; Uterus / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Analysis of polyamines in biological samples by HPLC involving pre-column derivatization with o-phthalaldehyde and N-acetyl-l-cysteine

Amino Acids, 46(6), 1557–1564.

By: Z. Dai *, Z. Wu *, J. Wang *, X. Wang* , S. Jia*, F. Bazer*, G. Wu *

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Polyamines; Derivatization; o-Phthalaldehyde; N-Acetyl-L-cysteine; HPLC
MeSH headings : Acetylcysteine / chemistry; Animals; Cells, Cultured / chemistry; Chromatography, High Pressure Liquid / methods; Plants / chemistry; Polyamines / analysis; Reproducibility of Results; Spectrometry, Fluorescence / methods; o-Phthalaldehyde / chemistry
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Arginine Decarboxylase and Agmatinase: An Alternative Pathway for De Novo Biosynthesis of Polyamines for Development of Mammalian Conceptuses

Biology of Reproduction, 90(4).

By: X. Wang* , W. Ying *, K. Dunlap*, G. Lin *, M. Satterfield*, R. Burghardt *, G. Wu *, F. Bazer

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: agmatine; development; polyamines; sheep; trophectoderm
MeSH headings : Agmatine / metabolism; Animals; Carboxy-Lyases / metabolism; Cationic Amino Acid Transporter 1 / genetics; Cationic Amino Acid Transporter 1 / metabolism; Citrulline / metabolism; Embryo Implantation / physiology; Embryonic Development / physiology; Female; Mammals; Nitric Oxide Synthase Type III / genetics; Nitric Oxide Synthase Type III / metabolism; Ornithine / metabolism; Ornithine Decarboxylase / genetics; Ornithine Decarboxylase / metabolism; Pregnancy; Pregnancy, Animal / physiology; Putrescine / biosynthesis; Sheep; Spermidine / biosynthesis; Spermine / biosynthesis; Ureohydrolases / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Environmental factors affecting pregnancy: Endocrine disrupters, nutrients and metabolic pathways

Molecular and Cellular Endocrinology, 398(1-2), 53–68.

By: F. Bazer*, G. Wu, G. Johnson * & X. Wang* 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Arginine; Glucose; Secreted phosphoprotein 1; Pregnancy; Endocrine Disrupter
MeSH headings : Agmatine / metabolism; Animals; Arginine / metabolism; Embryo Implantation; Embryonic Development; Endocrine Disruptors / adverse effects; Environment; Environmental Exposure / adverse effects; Estrogens / adverse effects; Female; Gene Expression Regulation, Developmental; High Fructose Corn Syrup / adverse effects; Humans; Infertility / chemically induced; Insulin Resistance; Metabolic Diseases / chemically induced; Nitric Oxide / biosynthesis; Phosphoproteins / metabolism; Polyamines / metabolism; Pregnancy; Prenatal Exposure Delayed Effects; Progestins / adverse effects
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Functional Role of Arginine During the Peri-implantation Period of Pregnancy. II. Consequences of Loss of Function of Nitric Oxide Synthase NOS3 mRNA in Ovine Conceptus Trophectoderm

Biology of Reproduction, 91(3).

By: X. Wang* , J. Frank*, J. Xu*, K. Dunlap*, M. Satterfield*, R. Burghardt *, J. Romero *, T. Hansen *, G. Wu *, F. Bazer

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: development; morpholino; nitric oxide; nitric oxide synthase
MeSH headings : Animals; Animals, Inbred Strains; Arginine / metabolism; Blastocyst / cytology; Blastocyst / drug effects; Blastocyst / metabolism; Blastocyst / pathology; Cationic Amino Acid Transporter 1 / metabolism; Embryo Implantation / drug effects; Embryo, Mammalian / cytology; Embryo, Mammalian / drug effects; Embryo, Mammalian / metabolism; Embryo, Mammalian / pathology; Embryonic Development / drug effects; Extraembryonic Membranes / cytology; Extraembryonic Membranes / drug effects; Extraembryonic Membranes / metabolism; Extraembryonic Membranes / pathology; Female; Fetal Growth Retardation / chemically induced; Fetal Growth Retardation / metabolism; Fetal Growth Retardation / pathology; Immunohistochemistry; Interferon Type I / metabolism; Morpholinos / pharmacology; Nitric Oxide Synthase Type III / antagonists & inhibitors; Nitric Oxide Synthase Type III / genetics; Nitric Oxide Synthase Type III / metabolism; Pregnancy; Pregnancy Maintenance / drug effects; Pregnancy Proteins / metabolism; RNA, Messenger / antagonists & inhibitors; RNA, Messenger / metabolism; Sheep, Domestic; Texas
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Functional role of arginine during the peri‐implantation period of pregnancy. I. Consequences of loss of function of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm

The FASEB Journal, 28(7), 2852–2863.

By: X. Wang* , J. Frank*, D. Little *, K. Dunlap*, M. Satterfield*, R. Burghardt *, T. Hansen *, G. Wu *, F. Bazer*

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: development; sheep; morpholino
MeSH headings : Amino Acids / genetics; Amino Acids / metabolism; Animals; Arginine / genetics; Arginine / metabolism; Cationic Amino Acid Transporter 1 / genetics; Cationic Amino Acid Transporter 1 / metabolism; Embryo Implantation / genetics; Embryo Implantation / physiology; Endometrium / metabolism; Endometrium / physiology; Female; Gene Expression Regulation, Developmental / genetics; Nitric Oxide Synthase Type III / genetics; Nitric Oxide Synthase Type III / metabolism; Ornithine Decarboxylase / genetics; Ornithine Decarboxylase / metabolism; Polyamines / metabolism; Pregnancy; RNA, Messenger / genetics; Sheep / genetics; Sheep / metabolism; Uterus / metabolism; Uterus / physiology
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Improving amino acid nutrition to prevent intrauterine growth restriction in mammals

Amino Acids, 46(7), 1605–1623.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Amino acids; Fetus; Intervention; IUGR; Nutrition; Placenta; Pregnancy
MeSH headings : Amino Acids / metabolism; Amino Acids / pharmacology; Animals; Arginine / metabolism; Arginine / pharmacology; Female; Fetal Growth Retardation / metabolism; Fetal Growth Retardation / prevention & control; Fetal Growth Retardation / veterinary; Mammals; Maternal Nutritional Physiological Phenomena; Placental Circulation; Pregnancy
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Putrescine Stimulates the mTOR Signaling Pathway and Protein Synthesis in Porcine Trophectoderm Cells

Biology of Reproduction, 91(5).

By: X. Kong *, X. Wang* , Y. Yin *, X. Li*, H. Gao *, F. Bazer*, G. Wu *

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: mTOR; placental cells; protein synthesis; putrescine
MeSH headings : Animals; Cell Proliferation / drug effects; Cells, Cultured; Ectoderm / drug effects; Ectoderm / metabolism; Eflornithine / pharmacology; Female; Pregnancy; Protein Biosynthesis / drug effects; Putrescine / pharmacology; Signal Transduction / drug effects; Swine; TOR Serine-Threonine Kinases / metabolism; Trophoblasts / drug effects; Trophoblasts / metabolism; Up-Regulation / drug effects
Sources: Crossref, ORCID
Added: May 4, 2020

2014 journal article

Temporal proteomic analysis reveals defects in small-intestinal development of porcine fetuses with intrauterine growth restriction

The Journal of Nutritional Biochemistry, 25(7), 785–795.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Intrauterine growth restriction; Fetus; Intestine; Development; Pig
MeSH headings : Animals; Animals, Newborn; Female; Fetal Growth Retardation / metabolism; Gestational Age; Intestinal Mucosa / metabolism; Intestine, Small / embryology; Intestine, Small / metabolism; Pregnancy; Proteome / metabolism; Swine
Sources: Crossref, ORCID
Added: May 4, 2020

2013 journal article

IUGR alters muscle fiber development and proteome in fetal pigsΒ 

Frontiers in Bioscience, 18(2), 598–607.

By: T. Wang*, C. Liu, C. Feng, X. Wang* , G. Lin, Y. Zhu, J. Yin, D. Li, J. Wang

co-author countries: China πŸ‡¨πŸ‡³
author keywords: IUGR; Muscle; Fetal Pigs; Proteome; Review
MeSH headings : Animals; Animals, Newborn; Female; Fetal Growth Retardation / metabolism; Fetal Weight; Muscle Development; Muscle Fibers, Skeletal / metabolism; Muscle Proteins / metabolism; Muscle, Skeletal / embryology; Muscle, Skeletal / metabolism; Pregnancy; Proteome; Sus scrofa
Sources: Crossref, ORCID
Added: January 21, 2021

2013 journal article

Impacts of arginine nutrition on embryonic and fetal development in mammals

Amino Acids, 45(2), 241–256.

By: G. Wu *, F. Bazer*, M. Satterfield*, X. Li*, X. Wang* , G. Johnson *, R. Burghardt *, Z. Dai *, J. Wang *, Z. Wu *

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Arginine; Cell signaling; Embryos; Nutrition; Reproduction
MeSH headings : Animals; Arginine / administration & dosage; Arginine / metabolism; Dietary Supplements; Embryo, Mammalian; Embryonic Development; Female; Fetal Growth Retardation / metabolism; Humans; Mice; Nutritional Status; Polyamines / metabolism; Pregnancy; Rats; Sheep, Domestic / embryology; Signal Transduction
Sources: Crossref, ORCID
Added: May 4, 2020

2013 journal article

Intrauterine growth restriction alters the hepatic proteome in fetal pigs

The Journal of Nutritional Biochemistry, 24(6), 954–959.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Fetus; Intrauterine growth restriction; Liver; Pigs; Proteome
MeSH headings : Animals; Animals, Newborn; Aspartate Aminotransferases / metabolism; Fetal Growth Retardation / metabolism; Fetal Weight; Fetus; Lipoprotein Lipase / metabolism; Liver / metabolism; Oxidative Stress; Proteome / metabolism; Proteomics; Swine
Sources: Crossref, ORCID
Added: May 4, 2020

2013 journal article

T Cells Development Is Different between Thymus from Normal and Intrauterine Growth Restricted Pig Fetus at Different Gestational Stage

Asian-Australasian Journal of Animal Sciences, 26(3), 343–348.

By: Y. Lin *, J. Wang *, X. Wang* , W. Wu* & C. Lai *

co-author countries: China πŸ‡¨πŸ‡³
author keywords: Intrauterine Growth Retardation; T Cell Development; Immunity; Notch Signaling; Pig Fetus
Sources: Crossref, ORCID
Added: May 4, 2020

2011 journal article

Dietary Supplementation with the Probiotic Lactobacillus fermentum I5007 and the Antibiotic Aureomycin Differentially Affects the Small Intestinal Proteomes of Weanling Piglets

The Journal of Nutrition, 142(1), 7–13.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Blotting, Western; Chlortetracycline / pharmacology; Dietary Supplements; Intestine, Small / drug effects; Intestine, Small / metabolism; Limosilactobacillus fermentum; Probiotics; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Weaning
Sources: Crossref, ORCID
Added: May 4, 2020

2010 journal article

Differential composition of proteomes in sow colostrum and milk from anterior and posterior mammary glands1

Journal of Animal Science, 88(8), 2657–2664.

By: W. Wu *, X. Wang* , G. Wu *, S. Kim n , F. Chen* & J. Wang*

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: W. Wu *, X. Wang* , G. Wu *, S. Kim n , F. Chen* & J. Wang*

author keywords: anterior mammary gland; colostrum; milk; posterior mammary gland; proteome; sow
MeSH headings : Animals; Animals, Suckling / growth & development; Blotting, Western / veterinary; Colostrum / chemistry; Electrophoresis, Gel, Two-Dimensional / veterinary; Female; Mammary Glands, Animal / physiology; Mass Spectrometry / veterinary; Milk / chemistry; Milk Proteins / analysis; Proteome / chemistry; Swine / metabolism
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2010 journal article

Temporal Proteomic Analysis Reveals Continuous Impairment of Intestinal Development in Neonatal Piglets with Intrauterine Growth Restriction

Journal of Proteome Research, 9(2), 924–935.

By: X. Wang* , W. Wu*, G. Lin *, D. Li *, G. Wu * & J. Wang *

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Intrauterine growth restriction; Piglets; Intestine; Development; Temporal proteomic analysis; Histological analysis
MeSH headings : Amino Acids / metabolism; Animals; Animals, Newborn; Apoptosis; Energy Metabolism; Fetal Growth Retardation / physiopathology; Homeostasis; Jejunum / embryology; Lipid Metabolism; Mass Spectrometry; Minerals / metabolism; Oxidation-Reduction; Proteome; Swine; Vitamins / metabolism
Sources: Crossref, ORCID
Added: May 4, 2020

2009 journal article

Advance in maternal bioactive compounds in promoting growth and development of piglets

Chinese Journal of Animal Science, 45(9), 61–64.

By: W. Wu, X. Wang  & J. Wang

Source: NC State University Libraries
Added: April 24, 2021

2009 journal article

Dietary L-arginine Supplementation Improves Intestinal Function in Weaned Pigs after an Escherichia coli Lipopolysaccharide Challenge

Asian-Australasian Journal of Animal Sciences, 22(12), 1667–1675.

By: Y. Liu, J. Han, J. Huang, X. Wang* , F. Wang & J. Wang

Sources: Crossref, ORCID
Added: May 4, 2020

2009 journal article

Progress in proteome research of breast milk

Chinese Journal of Animal Nutrition, 21(6), 809–815.

By: W. Wu, X. Wang  & J. Wang

Source: NC State University Libraries
Added: April 24, 2021

2009 journal article

Proteomic analysis reveals altered expression of proteins related to glutathione metabolism and apoptosis in the small intestine of zinc oxide-supplemented piglets

Amino Acids, 37(1), 209–218.

By: X. Wang* , D. Ou*, J. Yin *, G. Wu * & J. Wang *

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Apoptosis; Small intestine; Proteomics; Redox; ZnO
MeSH headings : Animals; Apoptosis / drug effects; Diarrhea / chemically induced; Diet; Dietary Supplements; Down-Regulation / physiology; Enzymes / biosynthesis; Glutathione / metabolism; Jejunum / cytology; Jejunum / drug effects; Jejunum / metabolism; Oxidative Stress / physiology; Proteomics; Swine; Up-Regulation / physiology; Zinc Oxide / administration & dosage
Sources: Crossref, ORCID
Added: May 4, 2020

2009 journal article

The development of T lymphocytes in intrauterine growth retardation piglets

Chinese Journal of Animal Science, 45(21), 13–15.

By: Y. Lin, J. Wang, X. Wang , W. Wu & C. Lai

Source: NC State University Libraries
Added: April 24, 2021

2008 journal article

Intrauterine Growth Restriction Affects the Proteomes of the Small Intestine, Liver, and Skeletal Muscle in Newborn Pigs

The Journal of Nutrition, 138(1), 60–66.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Animals, Newborn; Birth Weight; Female; Fetal Growth Retardation / metabolism; Gene Expression Profiling; Intestine, Small / growth & development; Intestine, Small / metabolism; Liver / growth & development; Liver / metabolism; Muscle Proteins / metabolism; Muscle, Skeletal / growth & development; Muscle, Skeletal / metabolism; Pregnancy; Proteome / metabolism; Swine / growth & development
Sources: Crossref, ORCID
Added: May 4, 2020

Employment

Updated: September 7th, 2018 11:46

2018 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Animal Science

2016 - 2018

National Institute of Environmental Health Sciences Durham, NC, US
Postdoctoral Fellow Reproductive and Development Biology Laboratory