Xiang Zhang

Works (10)

Updated: October 25th, 2025 05:04

2025 journal article

Doubly robust omnibus sensitivity analysis of externally controlled trials with intercurrent events

Biometrics, 81(2).

By: C. Gao n , X. Zhang* & S. Yang n 

author keywords: data heterogeneity; missing not at random; semi-parametric estimation; tilting models
MeSH headings : Humans; Biometry / methods; Randomized Controlled Trials as Topic / statistics & numerical data; Randomized Controlled Trials as Topic / methods; Computer Simulation; Models, Statistical; Data Interpretation, Statistical; Treatment Outcome; Controlled Clinical Trials as Topic / statistics & numerical data
topics (OpenAlex): Advanced Causal Inference Techniques; Statistical Methods in Clinical Trials; Statistical Methods and Inference
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: May 12, 2025

2025 journal article

Sensitivity Analysis for Unmeasured Confounding in Medical Product Development and Evaluation Using Real World Evidence

Statistics in Biopharmaceutical Research, 10, 1–12.

By: Y. Fang *, P. Mishra-Kalyani *, X. Zhang*, S. Gruber, S. Yang n , P. Ding *, M. Shan *, J. Lee * ...

author keywords: No unmeasured confounding; Observational studies; Real-world data; Real-world evidence; Sensitivity analysis
topics (OpenAlex): Health Systems, Economic Evaluations, Quality of Life; Pharmaceutical Economics and Policy; Statistical Methods in Clinical Trials
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 21, 2025

2024 journal article

Real Effect or Bias? Good Practices for Evaluating the Robustness of Evidence From Comparative Observational Studies Through Quantitative Sensitivity Analysis for Unmeasured Confounding

Pharmaceutical Statistics, 24(2).

By: D. Faries *, C. Gao n , X. Zhang*, C. Hazlett *, J. Stamey *, S. Yang n , P. Ding *, M. Shan *, K. Sheffield *, N. Dreyer

author keywords: bias; causal inference; confounding; real-world evidence; sensitivity
MeSH headings : Humans; Confounding Factors, Epidemiologic; Bias; Observational Studies as Topic / methods; Observational Studies as Topic / statistics & numerical data; Research Design / statistics & numerical data; Data Interpretation, Statistical; Computer Simulation; Causality
topics (OpenAlex): Health Systems, Economic Evaluations, Quality of Life; Advanced Causal Inference Techniques; Qualitative Comparative Analysis Research
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Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: December 16, 2024

2018 article

Tensor Generalized Estimating Equations for Longitudinal Imaging Analysis

Zhang, X., Li, L., Zhou, H., Zhou, Y., & Shen, D. (2018, February 8). Statistica Sinica.

By: X. Zhang n, L. Li*, H. Zhou*, Y. Zhou * & D. Shen *

author keywords: Generalized estimating equations; longitudinal imaging; low rank tensor decomposition; magnetic resonance imaging; multidimensional array; tensor regression
topics (OpenAlex): Tensor decomposition and applications; Advanced Neuroimaging Techniques and Applications; Sparse and Compressive Sensing Techniques
TL;DR: The proposed GEE approach accounts for intra-subject correlation, and an imposed low-rank structure on the coefficient tensor effectively reduces the dimensionality in several tensor generalized estimating equations (GEEs). (via Semantic Scholar)
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Source: Web Of Science
Added: September 30, 2019

2016 journal article

A consistent information criterion for support vector machines in diverging model spaces

Journal of Machine Learning Research, 17.

By: X. Zhang, Y. Wu, L. Wang & R. Li

Source: NC State University Libraries
Added: August 6, 2018

2016 article

A new PK equivalence test for a bridging study

Novick, S. J., Zhang, X., & Yang, H. (2016, February 16). Journal of Biopharmaceutical Statistics.

By: S. Novick, X. Zhang n & H. Yang

author keywords: Bayesian posterior probability; bioequivalence; concentration-time curve; pharmacokinetics
MeSH headings : Bayes Theorem; Biological Availability; Half-Life; Humans; Pharmaceutical Preparations / analysis; Pharmacokinetics; Therapeutic Equivalency
topics (OpenAlex): Statistical Methods in Clinical Trials; Statistical Distribution Estimation and Applications; Optimal Experimental Design Methods
TL;DR: An alternative metric of equivalence based on the maximum difference between PK profiles of the two formulations is proposed and it is shown that the new method provides better control over consumer’s risk. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2016 conference paper

Data-driven personas: Constructing archetypal users with clickstreams and user telemetry

34th Annual CHI Conference on Human Factors in Computing Systems, CHI 2016, 5350–5359.

By: X. Zhang, H. Brown & A. Shankar

Source: NC State University Libraries
Added: August 6, 2018

2016 article

System Reliability and Component Importance Under Dependence: A Copula Approach

Zhang, X., & Wilson, A. (2016, January 28). Technometrics, Vol. 59, pp. 215–224.

By: X. Zhang n & A. Wilson n 

author keywords: Dependent coherent system; Discrete marginal; Gaussian copula; Multi-state system
topics (OpenAlex): Reliability and Maintenance Optimization; Risk and Safety Analysis; Software Reliability and Analysis Research
TL;DR: This work characterize the influence of dependence structures on system reliability and component importance in coherent systems with discrete marginal distributions and extends the framework to coherent multi-state system. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 conference paper

Data-driven personas: Constructing archetypal users with clickstreams and user telemetry

34th Annual CHI Conference on Human Factors in Computing Systems, CHI 2016, 5350–5359.

By: X. Zhang, H. Brown & A. Shankar

Source: NC State University Libraries
Added: August 6, 2018

2015 article

Variable Selection for Support Vector Machines in Moderately High Dimensions

Zhang, X., Wu, Y., Wang, L., & Li, R. (2015, January 5). Journal of the Royal Statistical Society Series B (Statistical Methodology).

By: X. Zhang n, Y. Wu n, L. Wang * & R. Li *

author keywords: Local linear approximation; Non-convex penalty; Oracle property; Support vector machines; Ultrahigh dimensions; Variable selection
topics (OpenAlex): Face and Expression Recognition; Statistical Methods and Inference; Fault Detection and Control Systems
TL;DR: It is proved that, in ultrahigh dimensions, there is one local minimizer to the objective function of non‐convex penalized SVMs having the desired oracle property and the local linear approximation algorithm is guaranteed to converge to the oracle estimator even in the ultrahigh dimensional setting if an appropriate initial estimator is available. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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