Works (23)

Updated: April 11th, 2023 10:13

2023 article

Absorption rate governs cell transduction in dry macroporous scaffolds

VanBlunk, M., Srikanth, V., Pandit, S. S., Kuznetsov, A. V., & Brudno, Y. (2023, January 26). BIOMATERIALS SCIENCE.

Source: Web Of Science
Added: March 13, 2023

2022 article

Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells

Agarwalla, P., Ogunnaike, E. A., Ahn, S., Froehlich, K. A., Jansson, A., Ligler, F. S., … Brudno, Y. (2022, March 24). NATURE BIOTECHNOLOGY.

By: P. Agarwalla, E. Ogunnaike*, S. Ahn*, K. Froehlich n, A. Jansson, F. Ligler, G. Dotti*, Y. Brudno

Source: Web Of Science
Added: April 18, 2022

2022 journal article

Fabrication and Use of Dry Macroporous Alginate Scaffolds for Viral Transduction of T Cells

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (187).

By: M. VanBlunk, P. Agarwalla, S. Pandit & Y. Brudno

Source: Web Of Science
Added: January 30, 2023

2022 journal article

Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture

ACTA BIOMATERIALIA, 138, 208–217.

By: C. Moody, A. Brown, N. Massaro, A. Patel, P. Agarwalla, A. Simpson n, A. Brown n, H. Zheng, J. Pierce, Y. Brudno

author keywords: Alginate; Click chemistry; Bioconjugation; Ionic cross-linking; Drug capture
Sources: Web Of Science, ORCID
Added: October 31, 2021

2022 journal article

Tissue-reactive drugs enable materials-free local depots

JOURNAL OF CONTROLLED RELEASE, 343, 142–151.

By: S. Pandit, S. Palvai, N. Massaro, J. Pierce & Y. Brudno

author keywords: Sustained release; Materials-free delivery; Paclitaxel; Pancreatic cancer; Extracellular matrix; N-hydroxysuccinimide ester
Sources: Web Of Science, ORCID
Added: May 2, 2022

2021 journal article

On-Demand Drug Release from Click-Refillable Drug Depots

MOLECULAR PHARMACEUTICS, 18(10), 3920–3925.

By: S. Palvai, C. Moody, S. Pandit & Y. Brudno

author keywords: drug delivery; bioorthogonal; stimuli-responsive; photocleavage; click chemistry
Source: Web Of Science
Added: October 26, 2021

2020 journal article

Extracellular-Matrix-Anchored Click Motifs for Specific Tissue Targeting

MOLECULAR PHARMACEUTICS, 17(2), 392–403.

By: M. Adams n, C. Moody, J. Sollinger & Y. Brudno

author keywords: drug delivery; click chemistry; pancreatic cancer; brain delivery; extracellular matrix; computer modeling
Source: Web Of Science
Added: April 20, 2020

2020 journal article

In Vivo Targeting Using Arylboronate/Nopoldiol Click Conjugation

BIOCONJUGATE CHEMISTRY, 31(10), 2288–2292.

By: S. Palvai, J. Bhangu*, B. Akgun*, C. Moody, D. Hall* & Y. Brudno

Source: Web Of Science
Added: December 21, 2020

2020 journal article

Regenerating Antithrombotic Surfaces through Nucleic Acid Displacement

ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(4), 2159–2166.

By: S. McNamara*, Y. Brudno, A. Miller*, H. Ham*, M. Aizenberg*, E. Chaikof*, D. Mooney*

author keywords: blood-contacting devices; antithrombotic; refillable surface coatings; oligonucleotides; toehold exchange
Source: Web Of Science
Added: May 8, 2020

2020 journal article

Scaffold-Mediated Static Transduction of T Cells for CAR-T Cell Therapy

ADVANCED HEALTHCARE MATERIALS, 9(14).

By: P. Agarwalla, E. Ogunnaike*, S. Ahn*, F. Ligler, G. Dotti* & Y. Brudno

author keywords: alginate scaffold; CAR-T cells; cell therapy; immunotherapy; viral transduction
Source: Web Of Science
Added: June 29, 2020

2019 journal article

Biomimetics: Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury (Adv. Funct. Mater. 4/2019)

Advanced Functional Materials, 29(4), 1970019.

By: T. Su n, K. Huang n, H. Ma*, H. Liang n, P. Dinh n, J. Chen n, D. Shen n, T. Allen n ...

Source: Crossref
Added: February 21, 2020

2019 journal article

Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury

ADVANCED FUNCTIONAL MATERIALS, 29(4).

By: T. Su, K. Huang, H. Ma*, H. Liang, P. Dinh, J. Chen, D. Shen, T. Allen n ...

author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019

2018 journal article

Replenishable drug depot to combat post-resection cancer recurrence

BIOMATERIALS, 178, 373–382.

By: Y. Brudno, M. Pezone*, T. Snyder*, O. Uzun*, C. Moody, M. Aizenberg*, D. Mooney*

author keywords: Biomaterials; Drug delivery; Cancer therapy; Drug depot; Sustained release
Source: Web Of Science
Added: October 19, 2018

2015 journal article

In Vivo Targeting through Click Chemistry

ChemMedChem, 10(4), 617–620.

By: Y. Brudno, R. Desai*, B. Kwee*, N. Joshi*, M. Aizenberg* & D. Mooney*

author keywords: bioorthogonal chemistry; click chemistry; drug delivery; drug targeting; gels
Source: Crossref
Added: February 24, 2020

2015 journal article

On-demand drug delivery from local depots

Journal of Controlled Release, 219, 8–17.

By: Y. Brudno & D. Mooney*

author keywords: Drug delivery; Depot; Polymer; Therapeutic; On-demand; Ultrasound; Magnetic; Electric; Light; Pharmaceutical; Nucleic acid; Stimulated
Source: Crossref
Added: February 24, 2020

2014 journal article

Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart

Biomaterials, 35(25), 6850–6858.

By: E. Roche*, C. Hastings*, S. Lewin*, D. Shvartsman*, Y. Brudno, N. Vasilyev*, F. O'Brien*, C. Walsh*, G. Duffy*, D. Mooney*

author keywords: Alginate; Collagen; Cell viability; Heart; Hydrogel
Source: Crossref
Added: August 28, 2020

2014 journal article

Refilling drug delivery depots through the blood

Proceedings of the National Academy of Sciences, 111(35), 12722–12727.

By: Y. Brudno, E. Silva*, C. Kearney*, S. Lewin*, A. Miller*, K. Martinick*, M. Aizenberg*, D. Mooney*

author keywords: nanoparticle; targeting; DNA nanotechnology; controlled release; biomaterials
Source: Crossref
Added: August 28, 2020

2014 journal article

Sustained Delivery of VEGF Maintains Innervation and Promotes Reperfusion in Ischemic Skeletal Muscles Via NGF/GDNF Signaling

Molecular Therapy, 22(7), 1243–1253.

By: D. Shvartsman*, H. Storrie-White*, K. Lee*, C. Kearney*, Y. Brudno, N. Ho*, C. Cezar*, C. McCann* ...

Source: Crossref
Added: August 28, 2020

2013 journal article

Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors

Biomaterials, 34(36), 9201–9209.

By: Y. Brudno, A. Ennett-Shepard*, R. Chen*, M. Aizenberg* & D. Mooney*

author keywords: Controlled drug release; Angiogenesis; Growth factors; Drug delivery; Endothelial cell; Smooth muscle cell
Source: Crossref
Added: August 28, 2020

2011 journal article

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

Nature, 473(7347), 394–397.

By: W. Pastor*, U. Pape*, Y. Huang*, H. Henderson*, R. Lister*, M. Ko*, E. McLoughlin*, Y. Brudno ...

Source: Crossref
Added: August 28, 2020

2010 journal article

An in vitro translation, selection and amplification system for peptide nucleic acids

Nature Chemical Biology, 6(2), 148–155.

By: Y. Brudno, M. Birnbaum*, R. Kleiner* & D. Liu*

Source: Crossref
Added: October 29, 2020

2009 journal article

Recent Progress Toward the Templated Synthesis and Directed Evolution of Sequence-Defined Synthetic Polymers

Chemistry & Biology, 16(3), 265–276.

By: Y. Brudno & D. Liu*

Source: Crossref
Added: August 28, 2020

2008 journal article

DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes

Journal of the American Chemical Society, 130(14), 4646–4659.

By: R. Kleiner*, Y. Brudno, M. Birnbaum* & D. Liu*

Source: Crossref
Added: August 28, 2020