@article{wang_tzeng_huang_maguire_hoyo_allen_2023, title={Duration of exposure to epidural anesthesia at delivery, DNA methylation in umbilical cord blood and their association with offspring asthma in Non-Hispanic Black women}, volume={9}, ISSN={["2058-5888"]}, DOI={10.1093/eep/dvac026}, abstractNote={Abstract}, number={1}, journal={ENVIRONMENTAL EPIGENETICS}, author={Wang, Yaxu and Tzeng, Jung-Ying and Huang, Yueyang and Maguire, Rachel and Hoyo, Cathrine and Allen, Terrence K.}, year={2023}, month={Jan} }
 @article{chang_yang_lu_huang_huang_hung_miecznikowski_lu_tzeng_2021, title={Gene-set integrative analysis of multi-omics data using tensor-based association test}, volume={37}, ISSN={["1460-2059"]}, DOI={10.1093/bioinformatics/btab125}, abstractNote={Abstract}, number={16}, journal={BIOINFORMATICS}, author={Chang, Sheng-Mao and Yang, Meng and Lu, Wenbin and Huang, Yu-Jyun and Huang, Yueyang and Hung, Hung and Miecznikowski, Jeffrey C. and Lu, Tzu-Pin and Tzeng, Jung-Ying}, year={2021}, month={Aug}, pages={2259–2265} }
 @article{huang_tzeng_maguire_hoyo_allen_2020, title={The association between neuraxial anesthesia and the development of childhood asthma - a secondary analysis of the newborn epigenetics study cohort}, volume={36}, ISSN={["1473-4877"]}, DOI={10.1080/03007995.2020.1747417}, abstractNote={Abstract Objectives Childhood asthma is a common chronic illness that has been associated with mode of delivery. However, the effect of cesarean delivery alone does not fully account for the increased prevalence of childhood asthma. We tested the hypothesis that neuraxial anesthesia used for labor analgesia and cesarean delivery alters the risk of developing childhood asthma. Methods Within the Newborn Epigenetics Study birth cohort, 196 mother and child pairs with entries in the electronic anesthesia records were included. From these records, data on maternal anesthesia type, duration of exposure, and drugs administered peripartum were abstracted and combined with questionnaire-derived prenatal risk factors and medical records and questionnaire-derived asthma diagnosis data in children. Logistic regression models were used to evaluate associations between type of anesthesia, duration of anesthesia, and the development of asthma in males and females. Results We found that longer duration of epidural anesthesia was associated with a lower risk of asthma in male children (OR = 0.80; 95% CI = 0.66–0.95) for each hour of epidural exposure. Additionally, a unit increase in the composite dose of local anesthetics and opioid analgesics administered via the spinal route was associated with a lower risk of asthma in both male (OR = 0.59, 95% CI = 0.36–0.96) and female children (OR 0.26, 95% CI 0.09–0.82). Conclusion Our data suggest that peripartum exposure to neuraxial anesthesia may reduce the risk of childhood asthma primarily in males. Larger human studies and model systems with longer follow-up are required to elucidate these findings.}, number={6}, journal={CURRENT MEDICAL RESEARCH AND OPINION}, author={Huang, Yueyang and Tzeng, Jung-Ying and Maguire, Rachel and Hoyo, Cathrine and Allen, Terrence}, year={2020}, month={Jun}, pages={1025–1032} }
 @article{huang_alumasa_callaghan_baugh_rae_keiler_mcgillivray_2019, title={A Small-Molecule Inhibitor of trans-Translation Synergistically Interacts with Cathelicidin Antimicrobial Peptides To Impair Survival of Staphylococcus aureus}, volume={63}, ISSN={["1098-6596"]}, DOI={10.1128/AAC.02362-18}, abstractNote={
            Staphylococcus aureus
            is a leading cause of infection in the United States, and due to the rapid development of resistance, new antibiotics are constantly needed.
            trans
            -Translation is a particularly promising antibiotic target because it is conserved in many bacterial species, is critical for bacterial survival, and is unique among prokaryotes.
          }, number={4}, journal={ANTIMICROBIAL AGENTS AND CHEMOTHERAPY}, author={Huang, Yueyang and Alumasa, John N. and Callaghan, Lauren T. and Baugh, R. Samuel and Rae, Christopher D. and Keiler, Kenneth C. and McGillivray, Shauna M.}, year={2019}, month={Apr} }