Works (3)

Updated: July 5th, 2023 15:49

2011 journal article

The Effects of Weak Genetic Perturbations on the Transcriptome of the Wing Imaginal Disc and Its Association With Wing Shape in Drosophila melanogaster

GENETICS, 187(4), 1171–U314.

By: I. Dworkin n, J. Anderson n, Y. Idaghdour n, E. Parker n, E. Stone n & G. Gibson n

MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Drosophila melanogaster / growth & development; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, Insect; Genetic Variation; Genome, Insect; Genotype; Heterozygote; Linear Models; Multigene Family; Mutation; Phenotype; Transcriptional Activation; Wings, Animal / growth & development
TL;DR: Weak mutational perturbations in genes affecting wing development in Drosophila melanogaster that influence wing shape relative to a co-isogenic wild type are used to examine overall patterns of covariation between phenotypic variables of interest and underlying aspects of gene activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Geographical genomics of human leukocyte gene expression variation in southern Morocco

NATURE GENETICS, 42(1), 62–U79.

By: Y. Idaghdour n, W. Czika*, K. Shianna*, S. Lee*, P. Visscher*, H. Martin*, K. Miclaus*, S. Jadallah ...

MeSH headings : Arabs / genetics; Gene Expression Profiling / methods; Genetic Predisposition to Disease; Genetic Variation; Genetics, Population; Genome-Wide Association Study; Genomics / methods; Geography; Humans; Leukocytes / metabolism; Morocco; Polymorphism, Single Nucleotide; Principal Component Analysis
TL;DR: No evidence of large-effect trans-acting mediators of the pervasive environmental influence was found; instead, genetic and environmental factors acted in a largely additive manner. (via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs

Pharmacogenetics and Genomics, 19(12), 911–922.

By: E. Kennerly*, Y. Idaghdour*, N. Olby n, K. Munana n & G. Gibson*

Contributors: E. Kennerly*, Y. Idaghdour*, N. Olby n, K. Munana n & G. Gibson*

author keywords: canine epilepsy; drug response; epoxide hydrolase; GABRA2; KCNQ3; pharmacogenetics; phenobarbital; SCN2A2
MeSH headings : Animals; Anticonvulsants / metabolism; Anticonvulsants / therapeutic use; Case-Control Studies; Dog Diseases / drug therapy; Dogs; Drug Resistance; Epilepsy / drug therapy; Epilepsy / veterinary; Pharmacogenetics; Phenobarbital / metabolism; Phenobarbital / therapeutic use; Polymorphism, Single Nucleotide
TL;DR: Further replication and assessment of breed specificity is required before these markers can be considered as predictive of responsiveness to phenobarbital in dogs, but on functional grounds may tag strong candidate genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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