Yong-Jun Goh

Gilfillan, D., Vilander, A. C., Pan, M., Goh, Y. J., O'Flaherty, S., Feng, N., … Dean, G. A. (2023). <i>Lactobacillus acidophilus</i> Expressing Murine Rotavirus VP8 and Mucosal Adjuvants Induce Virus-Specific Immune Responses. VACCINES, 11(12). https://doi.org/10.3390/vaccines11121774

Pan, M., Morovic, W., Hidalgo-Cantabrana, C., Roberts, A., Walden, K. K. O., Goh, Y. J., & Barrangou, R. (2022). Genomic and epigenetic landscapes drive CRISPR-based genome editing in Bifidobacterium. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(30). https://doi.org/10.1073/pnas.2205068119

Goh, Y. J., Barrangou, R., & Klaenhammer, T. R. (2021). In Vivo Transcriptome of Lactobacillus acidophilus and Colonization Impact on Murine Host Intestinal Gene Expression. MBIO, 12(1). https://doi.org/10.1128/mBio.03399-20

Goh, Y. J., & Barrangou, R. (2021). Portable CRISPR-Cas9(N) System for Flexible Genome Engineering in Lactobacillus acidophilus, Lactobacillus gasseri, and Lactobacillus paracasei. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 87(6). https://doi.org/10.1128/AEM.02669-20

Andersen, S., Moller, M. S., Poulsen, J.-C. N., Pichler, M. J., Svensson, B., Lo Leggio, L., … Abou Hachem, M. (2020). An 1,4-alpha-Glucosyltransferase Defines a New Maltodextrin Catabolism Scheme in Lactobacillus acidophilus. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 86(15). https://doi.org/10.1128/AEM.00661-20

Pan, M., Hidalgo-Cantabrana, C., Goh, Y. J., Sanozky-Dawes, R., & Barrangou, R. (2020). Comparative Analysis of Lactobacillus gasseri and Lactobacillus crispatus Isolated From Human Urogenital and Gastrointestinal Tracts. FRONTIERS IN MICROBIOLOGY, 10. https://doi.org/10.3389/fmicb.2019.03146

Klotz, C., Goh, Y. J., O'Flaherty, S., Johnson, B., & Barrangou, R. (2020). Deletion of S-Layer Associated Ig-Like Domain Protein Disrupts the Lactobacillus acidophilus Cell Surface. FRONTIERS IN MICROBIOLOGY, 11. https://doi.org/10.3389/fmicb.2020.00345

Hidalgo-Cantabrana, C., Goh, Y. J., & Barrangou, R. (2019). [Review of Characterization and Repurposing of Type I and Type II CRISPR-Cas Systems in Bacteria]. JOURNAL OF MOLECULAR BIOLOGY, 431(1), 21–33. https://doi.org/10.1016/j.jmb.2018.09.013

Goh, Y. J., & Barrangou, R. (2019). [Review of Harnessing CRISPR-Cas systems for precision engineering of designer probiotic lactobacilli]. CURRENT OPINION IN BIOTECHNOLOGY, 56, 163–171. https://doi.org/10.1016/j.copbio.2018.11.009

Canez, C., Selle, K., Goh, Y. J., & Barrangou, R. (2019). Outcomes and characterization of chromosomal self-targeting by native CRISPR-Cas systems in Streptococcus thermophilus. FEMS MICROBIOLOGY LETTERS, 366(9). https://doi.org/10.1093/femsle/fnz105

Stout, E. A., Sanozky-Dawes, R., Goh, Y. J., Crawley, A. B., Klaenhammer, T. R., & Barrangou, R. (2018). Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri. MICROBIOLOGY-SGM, 164(9), 1098–1111. https://doi.org/10.1099/mic.0.000689

Moller, M. S., Goh, Y. J., Rasmussen, K. B., Cypryk, W., Celebioglu, H. U., Klaenhammer, T. R., … Abou Hachem, M. (2017). An Extracellular Cell-Attached Pullulanase Confers Branched alpha-Glucan Utilization in Human Gut Lactobacillus acidophilus. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 83(12). https://doi.org/10.1128/aem.00402-17

Selle, K., Goh, Y. J., Johnson, B. R., Sarah, O. F., Andersen, J. M., Barrangou, R., & Klaenhammer, T. R. (2017). Deletion of Lipoteichoic Acid Synthase Impacts Expression of Genes Encoding Cell Surface Proteins in Lactobacillus acidophilus. Frontiers in Microbiology, 8. https://doi.org/10.3389/fmicb.2017.00553

Klotz, C., O'Flaherty, S., Goh, Y. J., & Barrangou, R. (2017). Investigating the Effect of Growth Phase on the Surface-Layer Associated Proteome of Lactobacillus acidophilus Using Quantitative Proteomics. FRONTIERS IN MICROBIOLOGY, 8. https://doi.org/10.3389/fmicb.2017.02174

Theilmann, M. C., Goh, Y. J., Nielsen, K. F., Klaenhammer, T. R., Barrangou, R., & Abou Hachem, M. (2017). Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals. MBIO, 8(6). https://doi.org/10.1128/mbio.01421-17

Johnson, B. R., O'Flaherty, S., Goh, Y. J., Carroll, I., Barrangou, R., & Klaenhammer, T. R. (2017). The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface-Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM. FRONTIERS IN MICROBIOLOGY, 8. https://doi.org/10.3389/fmicb.2017.01185

Celebioglu, H. U., Ejby, M., Majumder, A., Kobler, C., Goh, Y. J., Thorsen, K., … Svensson, B. (2016). Differential proteome and cellular adhesion analyses of the probiotic bacterium Lactobacillus acidophilus NCFM grown on raffinose - an emerging prebiotic. PROTEOMICS, 16(9), 1361–1375. https://doi.org/10.1002/pmic.201500212

Hutkins, R. W., Krumbeck, J. A., Bindels, L. B., Cani, P. D., Fahey, G., Jr., Goh, Y. J., … Sanders, M. E. (2016). [Review of Prebiotics: why definitions matter]. CURRENT OPINION IN BIOTECHNOLOGY, 37, 1–7. https://doi.org/10.1016/j.copbio.2015.09.001

Goh, Y. J., & Klaenhammer, T. R. (2015). Genetic Mechanisms of Prebiotic Oligosaccharide Metabolism in Probiotic Microbes. ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 6, Vol. 6, pp. 137–156. https://doi.org/10.1146/annurev-food-022814-015706

Lightfoot, Y. L., Selle, K., Yang, T., Goh, Y. J., Sahay, B., Zadeh, M., … Mohamadzadeh, M. (2015). SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis. EMBO JOURNAL, 34(7), 881–895. https://doi.org/10.15252/embj.201490296

Call, E. K., Goh, Y. J., Selle, K., Klaenhammer, T. R., & O'Flaherty, S. (2015, February). Sortase-deficient lactobacilli: effect on immunomodulation and gut retention. MICROBIOLOGY-SGM, Vol. 161, pp. 311–321. https://doi.org/10.1099/mic.0.000007

Goh, Y. J., & Klaenhammer, T. R. (2014). [Review of Insights into glycogen metabolism in Lactobacillus acidophilus: impact on carbohydrate metabolism, stress tolerance and gut retention]. MICROBIAL CELL FACTORIES, 13. https://doi.org/10.1186/s12934-014-0094-3

Moller, M. S., Goh, Y. J., Viborg, A. H., Andersen, J. M., Klaenhammer, T. R., Svensson, B., & Abou Hachem, M. (2014). Recent insight in alpha-glucan metabolism in probiotic bacteria. BIOLOGIA, 69(6), 713–721. https://doi.org/10.2478/s11756-014-0367-7

Goh, Y. J., & Klaenhammer, T. R. (2013). A functional glycogen biosynthesis pathway in Lactobacillus acidophilus: expression and analysis of the glg operon. MOLECULAR MICROBIOLOGY, 89(6), 1187–1200. https://doi.org/10.1111/mmi.12338

Johnson, B., Selle, K., O'Flaherty, S., Goh, Y. J., & Klaenhammer, T. (2013). Identification of extracellular surface-layer associated proteins in Lactobacillus acidophilus NCFM. MICROBIOLOGY-SGM, 159, 2269–2282. https://doi.org/10.1099/mic.0.070755-0

Abou Hachem, M., Andersen, J. M., Barrangou, R., Moller, M. S., Fredslund, F., Majumder, A., … Svensson, B. (2013). [Review of Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria]. BIOCATALYSIS AND BIOTRANSFORMATION, 31(4), 226–235. https://doi.org/10.3109/10242422.2013.828048

Andersen, J. M., Barrangou, R., Abou Hachem, M., Lahtinen, S. J., Goh, Y. J., Svensson, B., & Klaenhammer, T. R. (2013). Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04. BMC GENOMICS, 14(1). https://doi.org/10.1186/1471-2164-14-312

Andersen, J. M., Barrangou, R., Abou Hachem, M., Lahtinen, S. J., Goh, Y.-J., Svensson, B., & Klaenhammer, T. R. (2012). Transcriptional Analysis of Prebiotic Uptake and Catabolism by Lactobacillus acidophilus NCFM. PLOS ONE, 7(9). https://doi.org/10.1371/journal.pone.0044409

Goh, Y. J., Goin, C., O'Flaherty, S., Altermann, E., & Hutkins, R. (2011, August 30). Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9. MICROBIAL CELL FACTORIES, Vol. 10. https://doi.org/10.1186/1475-2859-10-s1-s22

Andersen, J. M., Barrangou, R., Abou Hachem, M., Lahtinen, S., Goh, Y. J., Svensson, B., & Klaenhammer, T. R. (2011). Transcriptional and functional analysis of galactooligosaccharide uptake by lacS in Lactobacillus acidophilus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(43), 17785–17790. https://doi.org/10.1073/pnas.1114152108

Goh, Y. J., & Klaenhammer, T. R. (2010). Functional Roles of Aggregation-Promoting-Like Factor in Stress Tolerance and Adherence of Lactobacillus acidophilus NCFM. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(15), 5005–5012. https://doi.org/10.1128/aem.00030-10

Goh, Y. J., Azcarate-Peril, M. A., O'Flaherty, S., Durmaz, E., Valence, F., Jardin, J., … Klaenhammer, T. R. (2009). Development and Application of a upp-Based Counterselective Gene Replacement System for the Study of the S-Layer Protein SlpX of Lactobacillus acidophilus NCFM. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 75(10), 3093–3105. https://doi.org/10.1128/AEM.02502-08

Goh, Y. J., & Klaenhammer, T. R. (2009). [Review of Genomic features of Lactobacillus species]. Frontiers in Bioscience, 14, 1362–1386.

Azcarate-Peril, M. A., Altermann, E., Goh, Y. J., Tallon, R., Sanozky-Dawes, R. B., Pfeiler, E. A., … Klaenhammer, T. R. (2008, August). Analysis of the genome sequence of Lactobacillus gasseri ATCC 33323 reveals the molecular basis of an autochthonous intestinal organism. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 74, pp. 4610–4625. https://doi.org/10.1128/AEM.00054-08

Klaenhammer, T. R., Altermann, E., Pfeiler, E., Buck, B. L., Goh, Y.-J., O'Flaherty, S., … Duong, T. (2008, September). Functional genomics of probiotic Lactobacilli. JOURNAL OF CLINICAL GASTROENTEROLOGY, Vol. 42, pp. S160–S162. https://doi.org/10.1097/MCG.0b013e31817da140