Yingzhu Liu

Works (4)

Updated: July 30th, 2024 08:31

2024 journal article

Generation of High-Affinity Aptamers for Indazole Synthetic Cannabinoids

ANALYTICAL CHEMISTRY, 96(28), 11488–11497.

By: J. Canoura n, T. Nguyen n, C. Byrd n, R. Hill n, Y. Liu n & Y. Xiao n 

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2024

2023 article

Suite of Aptamer-Based Sensors for the Detection of Fentanyl and Its Analogues

Canoura, J., Liu, Y., Perry, J., Willis, C., & Xiao, Y. (2023, April 25). ACS SENSORS, Vol. 4.

By: J. Canoura n, Y. Liu n, J. Perry n, C. Willis n & Y. Xiao n 

author keywords: aptamers; fentanyl; analogue; electrochemistry; colorimetry; fluorescence; bioanalytical; sensors
MeSH headings : Humans; United States; Fentanyl; Analgesics, Opioid; Illicit Drugs; Drug Overdose; Immunoassay
TL;DR: A series of new aptamer-based assays and sensors that can detect fentanyl as well as several of its analogues in a reliable, accurate, rapid, and economic manner are developed and foresee the potential for routine use by medical and law enforcement personnel aswell as the general public to aid in rapid and accurate fentanyl identification. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023

2022 article

High-throughput quantitative binding analysis of DNA aptamers using exonucleases

Canoura, J., Alkhamis, O., Liu, Y., Willis, C., & Xiao, Y. (2022, December 30). NUCLEIC ACIDS RESEARCH, Vol. 12.

By: J. Canoura n, O. Alkhamis n, Y. Liu n, C. Willis n & Y. Xiao n 

MeSH headings : Aptamers, Nucleotide / chemical synthesis; Aptamers, Nucleotide / chemistry; Exonucleases; Ligands; Nucleic Acids; SELEX Aptamer Technique / methods; Fentanyl / analysis; Robotics
TL;DR: This work has developed a high-throughput method for accurately quantifying aptamer binding affinity, specificity, and cross-reactivity via the kinetics of aptamer digestion by exonucleases and this approach dramatically accelerates the aptamer characterization process and streamlines sensor development. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 17, 2023

2022 article

Near-Infrared Dye-Aptamer Assay for Small Molecule Detection in Complex Specimens

Jin, X., Liu, Y., Alkhamis, O., Canoura, J., Bacon, A., Xu, R., … Xiao, Y. (2022, July 7). ANALYTICAL CHEMISTRY, Vol. 7.

By: X. Jin *, Y. Liu n, O. Alkhamis n, J. Canoura n, A. Bacon n, R. Xu*, F. Fu *, Y. Xiao n 

MeSH headings : Aptamers, Nucleotide / chemistry; Biological Assay; Biosensing Techniques / methods
TL;DR: The utility of dye-aptamer NIR biosensors for high-throughput detection of analytes in clinical specimens is shown and the generality of this assay is demonstrated by detecting three different small-molecule analytes with their respective DNA aptamers at clinically relevant concentrations in serum and urine. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2022

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.