Works (4)
Updated: July 26th, 2024 05:00
2024 journal article
Generation of High-Affinity Aptamers for Indazole Synthetic Cannabinoids
ANALYTICAL CHEMISTRY, 96(28), 11488–11497.
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2024
2023 article
Suite of Aptamer-Based Sensors for the Detection of Fentanyl and Its Analogues
Canoura, J., Liu, Y., Perry, J., Willis, C., & Xiao, Y. (2023, April 25). ACS SENSORS, Vol. 4.
author keywords: aptamers; fentanyl; analogue; electrochemistry; colorimetry; fluorescence; bioanalytical; sensors
MeSH headings : Humans; United States; Fentanyl; Analgesics, Opioid; Illicit Drugs; Drug Overdose; Immunoassay
TL;DR:
A series of new aptamer-based assays and sensors that can detect fentanyl as well as several of its analogues in a reliable, accurate, rapid, and economic manner are developed and foresee the potential for routine use by medical and law enforcement personnel aswell as the general public to aid in rapid and accurate fentanyl identification.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023
2022 article
High-throughput quantitative binding analysis of DNA aptamers using exonucleases
Canoura, J., Alkhamis, O., Liu, Y., Willis, C., & Xiao, Y. (2022, December 30). NUCLEIC ACIDS RESEARCH, Vol. 12.
MeSH headings : Aptamers, Nucleotide / chemical synthesis; Aptamers, Nucleotide / chemistry; Exonucleases; Ligands; Nucleic Acids; SELEX Aptamer Technique / methods; Fentanyl / analysis; Robotics
TL;DR:
This work has developed a high-throughput method for accurately quantifying aptamer binding affinity, specificity, and cross-reactivity via the kinetics of aptamer digestion by exonucleases and this approach dramatically accelerates the aptamer characterization process and streamlines sensor development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 17, 2023
2022 article
Near-Infrared Dye-Aptamer Assay for Small Molecule Detection in Complex Specimens
Jin, X., Liu, Y., Alkhamis, O., Canoura, J., Bacon, A., Xu, R., … Xiao, Y. (2022, July 7). ANALYTICAL CHEMISTRY, Vol. 7.
MeSH headings : Aptamers, Nucleotide / chemistry; Biological Assay; Biosensing Techniques / methods
TL;DR:
The utility of dye-aptamer NIR biosensors for high-throughput detection of analytes in clinical specimens is shown and the generality of this assay is demonstrated by detecting three different small-molecule analytes with their respective DNA aptamers at clinically relevant concentrations in serum and urine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2022
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