Works (4)

Updated: July 5th, 2023 15:40

2020 journal article

Concise Synthesis and Antimicrobial Evaluation of the Guanidinium Alkaloid Batzelladine D: Development of a Stereodivergent Strategy

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(21), 9850–9857.

By: Y. Lin n, A. Ribaucourt n, Y. Moazami n & J. Pierce n

MeSH headings : Alkaloids / chemical synthesis; Alkaloids / chemistry; Alkaloids / pharmacology; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Microbial Sensitivity Tests; Molecular Conformation; Pyrimidines / chemical synthesis; Pyrimidines / chemistry; Pyrimidines / pharmacology; Staphylococcus aureus / drug effects; Stereoisomerism
TL;DR: The stereocontrolled synthesis allowed for the investigation of the antimicrobial activity of batzelladine D, demonstrating promising activity that is more potent for non-natural stereoisomers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: June 22, 2020

2016 journal article

Examining ubiquitinated peptide enrichment efficiency through an epitope labeled protein

ANALYTICAL BIOCHEMISTRY, 512, 114–119.

By: J. Parker n, Y. Oh n, Y. Moazami n, J. Pierce n, P. Loziuk n, R. Dean n, D. Muddiman n

author keywords: Ubiquitination; Gly-Gly enrichment; Enrichment efficiency
MeSH headings : Antibodies, Monoclonal, Murine-Derived / chemistry; Epitopes / chemistry; Muramidase / chemistry; Ubiquitinated Proteins / chemistry; Ubiquitination
TL;DR: It is shown that when conjugated to a lysine containing protein, such as lysozyme, it can be applied as a standard protein to examine ubiquitinated peptide enrichment within a complex background. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(16), 3091–3094.

By: Y. Moazami n, T. Gulledge n, S. Laster n & J. Pierce n

author keywords: Echinacea; Alkylamide; TNF-alpha; Anti-inflammatory; Cytokine
MeSH headings : Amides / chemical synthesis; Amides / chemistry; Amides / pharmacology; Animals; Cell Line; Echinacea / chemistry; Echinacea / metabolism; Fatty Acids / chemistry; Lipopolysaccharides / toxicity; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice; Plant Extracts / chemistry; Tumor Necrosis Factor-alpha / metabolism
TL;DR: The SAR of simple alkylamides found in Echinacea extracts with respect to their ability to decrease the production of the pro-inflammatory mediator TNF-α is explored. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Synthesis of 2,3-Dihydro-1,3-oxazin-4-ones via a Mild Formal [4+2] Cycloaddition of Acylketenes with Aldimines

Synthesis (Stuttgart), 47(21), 3363–3370.

By: Y. Moazami & J. Pierce

Source: NC State University Libraries
Added: August 6, 2018

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