Works (4)
Updated: July 5th, 2023 15:40
2020 journal article
Concise Synthesis and Antimicrobial Evaluation of the Guanidinium Alkaloid Batzelladine D: Development of a Stereodivergent Strategy
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(21), 9850–9857.
MeSH headings : Alkaloids / chemical synthesis; Alkaloids / chemistry; Alkaloids / pharmacology; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Microbial Sensitivity Tests; Molecular Conformation; Pyrimidines / chemical synthesis; Pyrimidines / chemistry; Pyrimidines / pharmacology; Staphylococcus aureus / drug effects; Stereoisomerism
TL;DR:
The stereocontrolled synthesis allowed for the investigation of the antimicrobial activity of batzelladine D, demonstrating promising activity that is more potent for non-natural stereoisomers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 22, 2020
2016 journal article
Examining ubiquitinated peptide enrichment efficiency through an epitope labeled protein
ANALYTICAL BIOCHEMISTRY, 512, 114–119.
author keywords: Ubiquitination; Gly-Gly enrichment; Enrichment efficiency
MeSH headings : Antibodies, Monoclonal, Murine-Derived / chemistry; Epitopes / chemistry; Muramidase / chemistry; Ubiquitinated Proteins / chemistry; Ubiquitination
TL;DR:
It is shown that when conjugated to a lysine containing protein, such as lysozyme, it can be applied as a standard protein to examine ubiquitinated peptide enrichment within a complex background.
(via Semantic Scholar)
open access via manuscript.elsevier.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Synthesis and biological evaluation of a series of fatty acid amides from Echinacea
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(16), 3091–3094.
author keywords: Echinacea; Alkylamide; TNF-alpha; Anti-inflammatory; Cytokine
MeSH headings : Amides / chemical synthesis; Amides / chemistry; Amides / pharmacology; Animals; Cell Line; Echinacea / chemistry; Echinacea / metabolism; Fatty Acids / chemistry; Lipopolysaccharides / toxicity; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice; Plant Extracts / chemistry; Tumor Necrosis Factor-alpha / metabolism
TL;DR:
The SAR of simple alkylamides found in Echinacea extracts with respect to their ability to decrease the production of the pro-inflammatory mediator TNF-α is explored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Synthesis of 2,3-Dihydro-1,3-oxazin-4-ones via a Mild Formal [4+2] Cycloaddition of Acylketenes with Aldimines
Synthesis (Stuttgart), 47(21), 3363–3370.
Source: NC State University Libraries
Added: August 6, 2018
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