Dr. Yi Xiao acquired her Ph.D. in Chemistry from Nanjing University (China) in 2000 under the supervision of Professor Hongyuan Chen. In 2001, she began her first post-doctoral appointment in Professor Itamar Willner's group at The Hebrew University of Jerusalem (Israel) developing optical and electrochemical biosensors and bioelectronics. In 2004, she started her second post-doctoral appointment at the University of California at Santa Barbara (UCSB), working with Nobel Laureate Professor Alan Heeger and Professor Kevin Plaxco to develop electrochemical sensors based on oligonucleotide receptors (aptamers). In 2007, she joined Professor H.T. Soh's laboratory at UCSB as a Research Professor, developing new methods to generate aptamers via SELEX. Dr. Xiao joined Florida International University in 2011 as an Assistant Professor and was promoted to tenured Associate Professor in 2017. She recently moved to the NC State Department of Chemistry as a tenured Associate Professor.

Works (153)

Updated: April 18th, 2023 07:18

2022 journal article

DNA Aptamer-Cyanine Complexes as Generic Colorimetric Small-Molecule Sensors

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 61(3).

By: O. Alkhamis, J. Canoura, K. Bukhryakov*, A. Tarifa*, A. DeCaprio* & Y. Xiao

author keywords: aptamers; colorimetric detection; cyanine dyes; dye-displacement; small-molecule targets
Sources: Web Of Science, ORCID
Added: April 18, 2022

2022 article

High-throughput quantitative binding analysis of DNA aptamers using exonucleases

Canoura, J., Alkhamis, O., Liu, Y., Willis, C., & Xiao, Y. (2022, December 30). NUCLEIC ACIDS RESEARCH, Vol. 12.

By: J. Canoura, O. Alkhamis, Y. Liu, C. Willis & Y. Xiao

Sources: Web Of Science, ORCID
Added: January 17, 2023

2022 article

Near-Infrared Dye-Aptamer Assay for Small Molecule Detection in Complex Specimens

Jin, X., Liu, Y., Alkhamis, O., Canoura, J., Bacon, A., Xu, R., … Xiao, Y. (2022, July 7). ANALYTICAL CHEMISTRY, Vol. 7.

By: X. Jin*, Y. Liu, O. Alkhamis, J. Canoura, A. Bacon n, R. Xu*, F. Fu*, Y. Xiao

Sources: Web Of Science, ORCID
Added: July 26, 2022

2022 article

Systematic Study of in Vitro Selection Stringency Reveals How To Enrich High-Affinity Aptamers

Alkhamis, O., & Xiao, Y. (2022, December 27). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 12.

By: O. Alkhamis & Y. Xiao

Sources: Web Of Science, ORCID
Added: January 17, 2023

2021 journal article

Advances and Challenges in Small‐Molecule DNA Aptamer Isolation, Characterization, and Sensor Development

Angewandte Chemie International Edition, 60(31), 16800–16923.

By: H. Yu*, O. Alkhamis*, J. Canoura*, Y. Liu* & Y. Xiao

author keywords: aptamers; biosensors; DNA; SELEX
Sources: Crossref, ORCID
Added: July 27, 2021

2021 journal article

Aptamer-Integrated Multianalyte-Detecting Paper Electrochemical Device

ACS Applied Materials & Interfaces, 13(15), 17330–17339.

By: Y. Liu*, O. Alkhamis*, X. Liu*, H. Yu*, J. Canoura* & Y. Xiao

author keywords: aptamer; small molecules; sensing; multianalyte detection; paper electrochemical device; ambient vacuum filtration
Sources: Crossref, ORCID
Added: July 27, 2021

2021 report

Aptamers that bind to natural and synthetic cannabinoids

(Patent No. US10907163B1).

By: H. Yu & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2021 conference paper

Development of Aptamer-Based Sensors for Sensitive and Specific Detection of Fentanyl Opioids

Presented at the Pittcon Conference and Expo.

By: J. Canoura, Y. Liu & Y. Xiao

Event: Pittcon Conference and Expo on March 11, 2021

Source: NC State University Libraries
Added: July 27, 2021

2021 journal article

Immobilization Strategies for Enhancing Sensitivity of Electrochemical Aptamer-Based Sensors

ACS Applied Materials & Interfaces, 13(8), 9491–9499.

By: Y. Liu*, J. Canoura*, O. Alkhamis* & Y. Xiao

author keywords: aptamer; electrochemistry; sensing; target-assisted aptamer immobilization; small molecules; bundling effect
Sources: Crossref, ORCID
Added: July 11, 2021

2021 journal article

Isolation of Natural DNA Aptamers for Challenging Small-Molecule Targets, Cannabinoids

Analytical Chemistry, 93(6), 3172–3180.

By: H. Yu*, Y. Luo*, O. Alkhamis*, J. Canoura*, B. Yu* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2021 report

Materials and methods for colorimetric detection of small molecule targets

(Patent No. US10948504B2).

By: H. Yu, Y. Luo & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2021 report

Method for isolating cross-reactive aptamer and use thereof

(Patent No. US10907162B2).

By: W. Yang, H. Yu, Y. Liu & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2021 article

Platinum-Nanoparticle-Modified Single-Walled Carbon Nanotube-Laden Paper Electrodes for Electrocatalytic Oxidation of Methanol

Paudyal, J., Wang, P., Zhou, F., Liu, Y., Cai, Y., & Xiao, Y. (2021, December 15). ACS APPLIED NANO MATERIALS, Vol. 12.

By: J. Paudyal*, P. Wang*, F. Zhou*, Y. Liu*, Y. Cai* & Y. Xiao

author keywords: paper electrode; vacuum filtration; single-walled carbon nanotube; platinum nanoclusters; electrochemical deposition; sensor
Sources: Web Of Science, ORCID
Added: January 3, 2022

2020 journal article

Accelerating Post-SELEX Aptamer Engineering Using Exonuclease Digestion

Journal of the American Chemical Society, 143(2), 805–816.

By: J. Canoura*, H. Yu*, O. Alkhamis*, D. Roncancio*, R. Farhana* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2020 conference paper

Achieving Near-ideal Binding Spectra using Subideal Bioreceptors

Presented at the Pittcon 2020, Chicago, Illinois.

By: Y. Liu, H. Yu, O. Alkhamis, J. Moliver & Y. Xiao

Event: Pittcon 2020 at Chicago, Illinois on March 1-5, 2020

Source: NC State University Libraries
Added: July 27, 2021

2020 speech

Beauty Through Simplicity – Problem-Driven Aptamer Science

Invited talk presented at the NC State University, Raleigh, NC.

By: Y. Xiao

Event: at NC State University, Raleigh, NC on January 9-10, 2020

Source: NC State University Libraries
Added: July 27, 2021

2020 journal article

Fabrication of Aptamer‐Modified Paper Electrochemical Devices for On‐Site Biosensing

Angewandte Chemie International Edition, 60(6), 2993–3000.

By: H. Yu*, Z. Chen*, Y. Liu*, O. Alkhamis*, Z. Song* & Y. Xiao

author keywords: aptamers; biosensors; nanomaterials; paper electrochemical devices; small molecules
Sources: Crossref, ORCID
Added: July 11, 2021

2020 conference paper

Isolation of Class-specific Aptamers and Development of Sensors for Instantaneous Detection of Synthetic Cathinones

Presented at the Pittcon, Chicago, IL.

By: Y. Xiao

Event: Pittcon at Chicago, IL on March 1-5, 2020

Source: NC State University Libraries
Added: July 27, 2021

2020 journal article

Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease

Nucleic Acids Research, 48(20), e120–e120.

By: O. Alkhamis*, W. Yang, R. Farhana*, H. Yu* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2020 report

Materials and methods for colorimetric detection of small molecule targets

(Patent No. US10725058B2).

By: Y. Xiao, Y. Luo & H. Yu

Source: NC State University Libraries
Added: July 27, 2021

2020 report

Materials and methods for rapid and sensitive detection of small-molecule targets

(Patent No. US10550395B2).

By: Y. Xiao & H. Yu

Source: NC State University Libraries
Added: July 27, 2021

2020 report

Materials and methods for rapid and specific detection of synthetic cathinones

(Patent No. US10683507B2).

By: Y. Xiao & H. Yu

Source: NC State University Libraries
Added: July 27, 2021

2020 report

Method for isolating cross-reactive aptamer and use thereof

(Patent No. US10655132B1).

By: W. Yang, H. Yu, Y. Liu & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2020 conference paper

Screening of aptamer mutants for enhanced target specificity using a dual exonuclease digestion assay

Presented at the Pittcon 2020, Chicago, Illinois.

By: J. Canoura, R. Farhana, R. Roncancio & Y. Xiao

Event: Pittcon 2020 at Chicago, Illinois on March 1-5, 2020

Source: NC State University Libraries
Added: July 27, 2021

2020 journal article

Tuning Biosensor Cross-Reactivity Using Aptamer Mixtures

Analytical Chemistry, 92(7), 5041–5047.

By: Y. Liu*, H. Yu*, O. Alkhamis*, J. Moliver* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2019 conference paper

A Cooperative-Binding Split Aptamer Assay for Rapid, Specific and Ultra-Sensitive Fluorescence Detection of Cocaine in Saliva

Presented at the Pittcon 2019, Philadelphia, Pennsylvania.

By: H. Yu, J. Canoura, B. Guntupalli & Y. Xiao

Event: Pittcon 2019 at Philadelphia, Pennsylvania on March 17-21, 2019

Source: NC State University Libraries
Added: July 27, 2021

2019 conference paper

Beauty Through Simplicity – Functionalized Aptamers for On-Site Small-Molecule Detection

Presented at the Pittcon 2019, Philadelphia, Pennsylvania.

By: Y. Xiao

Event: Pittcon 2019 at Philadelphia, Pennsylvania on March 17-21, 2019

Source: NC State University Libraries
Added: July 27, 2021

2019 conference paper

Development of Electrochemical Aptamer-Based Sensors for On-Site Synthetic Cathinone Detection

Presented at the Pittcon 2019, Philadelphia, Pennsylvanis.

By: Y. Liu, O. Alkhamis, H. Yu & Y. Xiao

Event: Pittcon 2019 at Philadelphia, Pennsylvanis on March 17-21, 2019

Source: NC State University Libraries
Added: July 27, 2021

2019 report

Highly conductive porous paper-based metal thin films

(Patent No. US10290386B2).

By: Y. Xiao, B. Guntupalli & J. Paudyal

Source: NC State University Libraries
Added: July 27, 2021

2019 conference paper

In Vitro Isolation of Small-Molecule-Binding Aptamers with Intrinsic Dye-Displacement Functionality

Presented at the Pittcon 2019, Philadelphia, Pennsylvania.

By: H. Yu, W. Yang, O. Alkhamis, J. Canoura, K. Yang & Y. Xiao

Event: Pittcon 2019 at Philadelphia, Pennsylvania on March 17-21, 2019

Source: NC State University Libraries
Added: July 27, 2021

2019 journal article

In vitro isolation of class-specific oligonucleotide-based small-molecule receptors

Nucleic Acids Research, 47(12), e71–e71.

By: W. Yang, H. Yu*, O. Alkhamis*, Y. Liu*, J. Canoura*, F. Fu*, Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2019 journal article

Innovative engineering and sensing strategies for aptamer-based small-molecule detection

TrAC Trends in Analytical Chemistry, 121, 115699.

By: O. Alkhamis*, J. Canoura*, H. Yu*, Y. Liu* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2019 conference paper

Introducing Structure-Switching Functionality into Small-Molecule-Binding Aptamers via Nuclease-Directed Truncation

Presented at the Pittcon 2019, Philadelphia, Pennsylvania.

By: Z. Wang, H. Yu, J. Canoura, Y. Liu, O. Alkhamis, F. Fu, Y. Xiao

Event: Pittcon 2019 at Philadelphia, Pennsylvania on March 17-21, 2019

Source: NC State University Libraries
Added: July 27, 2021

2019 journal article

Label-Free, Visual Detection of Small Molecules Using Highly Target-Responsive Multimodule Split Aptamer Constructs

Analytical Chemistry, 91(11), 7199–7207.

By: Y. Luo*, H. Yu*, O. Alkhamis*, Y. Liu*, X. Lou*, B. Yu*, Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2019 journal article

Perspective on the Future Role of Aptamers in Analytical Chemistry

Analytical Chemistry, 91(24), 15335–15344.

By: Y. Wu*, I. Belmonte*, K. Sykes*, Y. Xiao & R. White*

Sources: Crossref, ORCID
Added: July 11, 2021

2019 conference paper

Rapid, naked-eye screening for synthetic cathinones based on cross-reactive aptamers

Presented at the Pittcon 2019, Philadelphia, Pennsylvania.

By: W. Yang, H. Yu, O. Alkhamis, F. Fu & Y. Xiao

Event: Pittcon 2019 at Philadelphia, Pennsylvania on March 17-21, 2019

Source: NC State University Libraries
Added: July 27, 2021

2019 journal article

Universal Design of Structure-Switching Aptamers with Signal Reporting Functionality

Analytical Chemistry, 91(22), 14514–14521.

By: H. Gao*, J. Zhao*, Y. Huang*, X. Cheng*, S. Wang*, Y. Han*, Y. Xiao, X. Lou*

Sources: Crossref, ORCID
Added: July 11, 2021

2018 conference paper

Aptamer-based Assays for On-site Drug Detection

Presented at the Pittcon 2018, Orlando, Florida.

By: Y. Xiao

Event: Pittcon 2018 at Orlando, Florida on February 26 - March 1, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 speech

Beauty through simplicity – functionalized aptamers for on-site small-molecule detection

Invited talk presented at the University of Notre Dame, South Bend, Indiana.

By: Y. Xiao

Event: at University of Notre Dame, South Bend, Indiana on September 17, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 journal article

Dithiothreitol-Regulated Coverage of Oligonucleotide-Modified Gold Nanoparticles To Achieve Optimized Biosensor Performance

ACS Applied Materials & Interfaces, 10(4), 4233–4242.

By: P. Liang*, J. Canoura*, H. Yu*, O. Alkhamis* & Y. Xiao

author keywords: gold nanoparticles; DNA surface coverage; dithiothreitol; enzyme-assisted target recycling; DNA detection; cocaine detection
Sources: Crossref, ORCID
Added: July 11, 2021

2018 journal article

In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality

Nucleic Acids Research, 46(8), e43–e43.

By: H. Yu*, W. Yang*, O. Alkhamis*, J. Canoura*, K. Yang & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2018 journal article

Introducing structure-switching functionality into small-molecule-binding aptamers via nuclease-directed truncation

Nucleic Acids Research, 46(13), e81–e81.

By: Z. Wang*, H. Yu*, J. Canoura*, Y. Liu*, O. Alkhamis*, F. Fu*, Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2018 report

Materials and methods for rapid visualization of NAD(P)H

(Patent No. US10000790B2).

By: P. Liang, H. Yu & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2018 journal article

No Structure-Switching Required: A Generalizable Exonuclease-Mediated Aptamer-Based Assay for Small-Molecule Detection

Journal of the American Chemical Society, 140(31), 9961–9971.

By: J. Canoura*, Z. Wang*, H. Yu*, O. Alkhamis*, F. Fu* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2018 conference paper

Rapid and sensitive detection of small-molecule targets via enzyme-assisted target recycling based on cooperative binding split aptamers

Presented at the Pittcon 2018, Orlando, Florida.

By: H. Yu, J. Canoura, B. Guntupalli, X. Lou & Y. Xiao

Event: Pittcon 2018 at Orlando, Florida on February 26 - March 1, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 journal article

Sensitive Detection of Small-Molecule Targets Using Cooperative Binding Split Aptamers and Enzyme-Assisted Target Recycling

Analytical Chemistry, 90(3), 1748–1758.

By: H. Yu*, J. Canoura*, B. Guntupalli*, O. Alkhamis* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2018 conference paper

Utilizing nuclease screening of ligand-aptamer complexes to enhance specificity of an aptamer-based cocaine assay

Presented at the 2017 Society of Forensic Toxicologists-International Association of Forensic Toxicologists (SOFT-TIAFT) Joint Meeting, Boca Raton, Florida.

By: Z. Wang, J. Canoura, H. Yu & Y. Xiao

Event: 2017 Society of Forensic Toxicologists-International Association of Forensic Toxicologists (SOFT-TIAFT) Joint Meeting at Boca Raton, Florida on January 7-11, 2018

Source: NC State University Libraries
Added: July 27, 2021

2017 journal article

A Broadly Applicable Assay for Rapidly and Accurately Quantifying DNA Surface Coverage on Diverse Particles

Bioconjugate Chemistry, 28(4), 933–943.

By: H. Yu*, X. Xu*, P. Liang*, K. Loh*, B. Guntupalli*, D. Roncancio*, Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2017 conference paper

A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva

Poster presented at the Gordon Research Conference: Nucleosides, Nucleotides & Oligonucleotides, Salve Regina University, Newport, RI.

By: H. Yu, J. Canoura, B. Guntupalli & Y. Xiao

Event: Gordon Research Conference: Nucleosides, Nucleotides & Oligonucleotides at Salve Regina University, Newport, RI on June 25-30, 2017

Source: NC State University Libraries
Added: September 6, 2021

2017 journal article

A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva

Chemical Science, 8(1), 131–141.

By: H. Yu*, J. Canoura*, B. Guntupalli*, X. Lou* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2017 conference paper

A label-free aptamer-fluorophore assembly for highly sensitive and specific detection of cocaine

Presented at the Pittcon 2017, Chicago, Illinois.

By: D. Roncancio, H. Yu, X. Xu & Y. Xiao

Event: Pittcon 2017 at Chicago, Illinois on March 5-9, 2017

Source: NC State University Libraries
Added: September 11, 2021

2017 conference paper

Cooperative-binding split aptamer assays for rapid, specific and ultra-sensitive detection of small-molecule targets in biofluid samples

Invited talk presented at the 2017 American Chemical Society Florida Annual Meeting and Exposition, Tampa, FL.

By: H. Yu, J. Canoura, B. Guntupalli & Y. Xiao

Event: 2017 American Chemical Society Florida Annual Meeting and Exposition at Tampa, FL on May 5-6, 2017

Source: NC State University Libraries
Added: September 6, 2021

2017 conference paper

Gold nanoparticle-based assays for rapid and sensitive colorimetric and electrochemical biosensing

Presented at the Nano Florida 2017, Florida International University, Miami, FL.

By: Y. Xiao

Event: Nano Florida 2017 at Florida International University, Miami, FL on September 23-24, 2017

Source: NC State University Libraries
Added: August 27, 2021

2017 speech

Gold nanoparticle-based, paper devices for rapid and sensitive colorimetric and electrochemical biosensing

Invited talk presented at the 2017 American Chemical Society Florida Annual Meeting and Exposition, Tampa, FL.

By: P. Liang, B. Guntupalli, H. Yu & Y. Xiao

Event: 2017 American Chemical Society Florida Annual Meeting and Exposition at Tampa, FL on May 5-6, 2017

Source: NC State University Libraries
Added: September 6, 2021

2017 report

Materials and methods for rapid and specific detection of cocaine

(Patent No. US9804178B2).

By: D. Roncancio, H. Yu, X. Xu & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2017 conference paper

Rapid and sensitive detection of small-molecule targets via enzyme-assisted target recycling based on cooperative binding split aptamers

Poster presented at the Gordon Research Conference: Nucleosides, Nucleotides & Oligonucleotides, Salve Regina University, Newport, RI.

By: H. Yu, J. Canoura, B. Guntupalli, X. Lou & Y. Xiao

Event: Gordon Research Conference: Nucleosides, Nucleotides & Oligonucleotides at Salve Regina University, Newport, RI on June 25-30, 2017

Source: NC State University Libraries
Added: September 6, 2021

2017 conference paper

Utilizing dual-enzyme selectivity for the identification of aptamer binding domains and the development of sensitive fluorescence detection of small-molecule targets

Presented at the FIU Annual Scholarly Forum, Graduate Student Appreciation Week (GSAW), Florida International University, Miami, FL.

By: J. Canoura, Z. Wang, H. Yu & Y. Xiao

Event: FIU Annual Scholarly Forum, Graduate Student Appreciation Week (GSAW) at Florida International University, Miami, FL on March 27-28, 2017

Source: NC State University Libraries
Added: September 11, 2021

2017 conference paper

Utilizing nuclease screening of ligand-aptamer complexes to enhance specificity of an aptamer-based cocaine assay

Poster presented at the Gordon Research Conference: Nucleosides, Nucleotides & Oligonucleotides, Salve Regina University, Newport, RI.

By: J. Canoura, Z. Wang, H. Yu & Y. Xiao

Event: Gordon Research Conference: Nucleosides, Nucleotides & Oligonucleotides at Salve Regina University, Newport, RI on June 25-30, 2017

Source: NC State University Libraries
Added: September 6, 2021

2016 conference paper

A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva

Presented at the Pittcon 2017, Chicago, Illinois.

By: H. Yu, J. Canoura, B. Guntupalli & Y. Xiao

Event: Pittcon 2017 at Chicago, Illinois on March 5-9, 2017

Source: NC State University Libraries
Added: September 11, 2021

2016 conference paper

A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva

Presented at the 2016 Conference of Undergraduate Research at FIU (CURFIU), Miami, FL.

By: H. Yu, B. Guntupalli & Y. Xiao

Event: 2016 Conference of Undergraduate Research at FIU (CURFIU) at Miami, FL on March 30-31, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 conference paper

A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva

Presented at the FIU Annual Scholarly Forum, Graduate Student Appreciation Week (GSAW), Florida International University, Miami, FL.

By: Y. H.X., G. B. & X. Y

Event: FIU Annual Scholarly Forum, Graduate Student Appreciation Week (GSAW) at Florida International University, Miami, FL on March 28-29, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 conference paper

A label-free aptamer-fluorophore assembly for highly sensitive and specific detection of cocaine

Presented at the 2016 Conference of Undergraduate Research at FIU (CURFIU), Miami, FL.

By: D. Roncancio, H. Yu, X. Xu, S. Wu, R. Liu, J. Debord, X. Lou, Y. Xiao

Event: 2016 Conference of Undergraduate Research at FIU (CURFIU) at Miami, FL on March 30-31, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 conference paper

Ambient filtration method to rapidly prepare highly conductive, paper-based porous gold films for electrochemical biosensing

Presented at the 2016 Conference of Undergraduate Research at FIU (CURFIU), Miami, FL.

By: B. Guntupalli, P. Liang, J. Lee, Y. Yang, H. Yu, J. Canoura, J. He, W. Li, Y. Weizmann, Y. Xiao

Event: 2016 Conference of Undergraduate Research at FIU (CURFIU) at Miami, FL on March 30-31, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 speech

Bringing biosensors to the bedside

Invited talk presented at the University of Miami, Medical Campus - Batchelor Children's Research Institute, Miami, FL.

By: Y. Xiao

Event: at University of Miami, Medical Campus - Batchelor Children's Research Institute, Miami, FL on May 18, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 conference paper

Paper-based device for rapid visualization of NADH based on dissolution of gold nanoparticles

Poster presented at the 2016 Conference of Undergraduate Research at FIU (CURFIU), Miami, FL.

By: P. Liang, H. Yu, B. Guntupalli & Y. Xiao

Event: 2016 Conference of Undergraduate Research at FIU (CURFIU) at Miami, FL on March 30-31, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 conference paper

Paper-based devices for rapid and sensitive colorimetric and electrochemical biosensing

Invited talk presented at the 2016 ACS Florida Annual Meeting and Exposition, Tampa, FL.

By: Y. Xiao

Event: 2016 ACS Florida Annual Meeting and Exposition at Tampa, FL on May 5-7, 2016

Source: NC State University Libraries
Added: September 11, 2021

2016 journal article

Rapid, Surfactant-Free, and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA under Physiological pH and Its Application in Molecular Beacon-Based Biosensor

ACS Applied Materials & Interfaces, 8(40), 27298–27304.

By: Q. Xu*, X. Lou*, L. Wang*, X. Ding*, H. Yu* & Y. Xiao

author keywords: gold nanoparticle; thiolated DNA; DNA-gold nanoparticle conjugates; ethylene glycol spacer; physiological pH; adsorption kinetics; quantitative adsorption
Sources: Crossref, ORCID
Added: July 11, 2021

2016 conference paper

Utilizing nuclease screening of ligand-aptamer complexes to enhance specificity of an aptamer-based cocaine assay

Poster presented at the 2016 ACS Florida Annual Meeting and Exposition, Tampa, FL.

By: J. Canoura, Z. Wang, H. Yu, B. Ng, D. Roncancio & Y. Xiao

Event: 2016 ACS Florida Annual Meeting and Exposition at Tampa, FL on May 5-7, 2016

Source: NC State University Libraries
Added: September 11, 2021

2015 conference paper

A paper-based device for rapid visualization of NADH based on dissolution of gold nanoparticles

Poster presented at the 2015 Materials Research Society (MRS) Fall Meeting & Exhibit, Boston, Massachusetts.

By: P. Liang, H. Yu & Y. Xiao

Event: 2015 Materials Research Society (MRS) Fall Meeting & Exhibit at Boston, Massachusetts on November 29 - December 4, 2015

Source: NC State University Libraries
Added: September 11, 2021

2015 journal article

Ambient Filtration Method To Rapidly Prepare Highly Conductive, Paper-Based Porous Gold Films for Electrochemical Biosensing

ACS Applied Materials & Interfaces, 7(49), 27049–27058.

By: B. Guntupalli*, P. Liang*, J. Lee*, Y. Yang*, H. Yu*, J. Canoura*, J. He*, W. Li*, Y. Weizmann*, Y. Xiao

author keywords: gold nanoparticles; single-walled carbon nanotubes; paper-based hybrid porous gold film; vacuum filtration; electrocatalytic response; film conductivity
Sources: Crossref, ORCID
Added: July 11, 2021

2015 conference paper

Ambient filtration method to rapidly prepare highly conductive, paper-based porous gold films

Presented at the 2015 Materials Research Society (MRS) Fall Meeting & Exhibit, Boston, Massachusetts.

By: B. Guntupalli, P. Liang, Y. Yang, J. He, W. Li & Y. Xiao

Event: 2015 Materials Research Society (MRS) Fall Meeting & Exhibit at Boston, Massachusetts on November 29 - December 4, 2015

Source: NC State University Libraries
Added: September 11, 2021

2015 conference paper

Amplified colorimetric detection of cocaine in oral fluid based on exonuclease-assisted aptamer strand recycling

Poster presented at the Society of Forensic Toxicologists (SOFT) 2015 Annual Meeting, Atlanta, Georgia.

By: Z. Wang, H. Yu, B. Ng, D. Roncancio, J. Canoura & Y. Xiao

Event: Society of Forensic Toxicologists (SOFT) 2015 Annual Meeting at Atlanta, Georgia on October 19-23, 2015

Source: NC State University Libraries
Added: September 11, 2021

2015 speech

Aptamer-based, exonuclease-amplified, paper device for point of collection screening of cocaine and methamphetamine in oral fluid

Invited talk presented at the Forensic Science R&D Grantees Meeting, Orlando, FL.

By: Y. Xiao

Event: Forensic Science R&D Grantees Meeting at Orlando, FL on February 17, 2015

Source: NC State University Libraries
Added: September 11, 2021

2015 conference paper

Base-pair mismatch detection

Invited talk presented at the FIU Biomolecular Sciences Institute Symposium on DNA Repair and Genome Stability: In honor of the 2015 Nobel Prize in Chemistry for DNA Repair, Miami, FL.

By: Y. Xiao

Event: FIU Biomolecular Sciences Institute Symposium on DNA Repair and Genome Stability: In honor of the 2015 Nobel Prize in Chemistry for DNA Repair at Miami, FL on December 16, 2015

Source: NC State University Libraries
Added: September 11, 2021

2015 speech

Bringing biosensors to the bedside

Recruitment talk presented at the Division of Health and Natural Sciences, Florida Memorial University, Miami, FL.

By: Y. Xiao

Event: at Division of Health and Natural Sciences, Florida Memorial University, Miami, FL on February 24, 2015

Source: NC State University Libraries
Added: September 11, 2021

2015 journal article

Nanoprobe-Enhanced, Split Aptamer-Based Electrochemical Sandwich Assay for Ultrasensitive Detection of Small Molecules

Analytical Chemistry, 87(15), 7712–7719.

By: T. Zhao*, R. Liu*, X. Ding*, J. Zhao*, H. Yu*, L. Wang*, Q. Xu*, X. Wang* ...

Sources: Crossref, ORCID
Added: July 11, 2021

2015 journal article

Paper-Based Device for Rapid Visualization of NADH Based on Dissolution of Gold Nanoparticles

ACS Applied Materials & Interfaces, 7(27), 15023–15030.

By: P. Liang*, H. Yu*, B. Guntupalli* & Y. Xiao

author keywords: dissolution of gold nanoparticles; dihydronicotinamide adenine dinucleotide; paper-based device; colorimetric screening; dehydrogenase inhibitors; NAD(+)-driven enzymatic reactions
Sources: Crossref, ORCID
Added: July 11, 2021

2015 conference paper

Simple, rapid and ultra-sensitive fluorescence detection of cocaine in oral fluid based on cooperative binding split aptamer

Presented at the Society of Forensic Toxicologists (SOFT) 2015 Annual Meeting, Atlanta, Georgia.

By: H. Yu, Z. Wang, B. Ng, J. Canoura & Y. Xiao

Event: Society of Forensic Toxicologists (SOFT) 2015 Annual Meeting at Atlanta, Georgia on October 19-23, 2015

Source: NC State University Libraries
Added: September 11, 2021

2014 journal article

A Label-Free Aptamer-Fluorophore Assembly for Rapid and Specific Detection of Cocaine in Biofluids

Analytical Chemistry, 86(22), 11100–11106.

By: D. Roncancio*, H. Yu*, X. Xu*, S. Wu*, R. Liu*, J. Debord*, X. Lou*, Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2014 conference paper

A label-free aptamer-fluorophore assembly for highly sensitive and specific detection of cocaine

Poster presented at the 2014 Materials Research Society (MRS) Fall Meeting & Exhibit, Boston, Massachusetts.

By: D. Roncancio, S. Wu, H. Yu, X. Xu, R. Liu, J. Debord, X. Lou, Y. Xiao

Event: 2014 Materials Research Society (MRS) Fall Meeting & Exhibit at Boston, Massachusetts on November 30 - December 5, 2014

Source: NC State University Libraries
Added: September 11, 2021

2014 journal article

Amplified Single Base-Pair Mismatch Detection via Aggregation of Exonuclease-Sheared Gold Nanoparticles

Analytical Chemistry, 86(7), 3461–3467.

By: S. Wu*, P. Liang*, H. Yu*, X. Xu*, Y. Liu*, X. Lou*, Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2014 conference paper

Amplified single base-pair mismatch detection via the aggregation of exonuclease-sheared gold nanoparticles

Poster presented at the 2014 Materials Research Society (MRS) Fall Meeting & Exhibit, Boston, Massachusetts.

By: S. Wu, P. Liang, H. Yu, X. Xu, Y. Liu, X. Lou, Y. Xiao

Event: 2014 Materials Research Society (MRS) Fall Meeting & Exhibit at Boston, Massachusetts on November 30 - December 5, 2014

Source: NC State University Libraries
Added: September 11, 2021

2014 speech

Bringing biosensors to the bedside

Recruitment talk presented at the Department of Chemistry, St. Thomas University, Miami, FL.

By: Y. Xiao

Event: at Department of Chemistry, St. Thomas University, Miami, FL on November 5, 2014

Source: NC State University Libraries
Added: September 11, 2021

2014 conference paper

Target recycling-based assay for rapid and accurate determination of DNA surface coverage on gold nanoparticles

Presented at the 2014 Materials Research Society (MRS) Fall Meeting & Exhibit, Boston, Massachusetts.

By: X. Xu, B. Guntupalli, H. Yu & Y. Xiao

Event: 2014 Materials Research Society (MRS) Fall Meeting & Exhibit at Boston, Massachusetts on November 30 - December 5, 2014

Source: NC State University Libraries
Added: September 11, 2021

2013 conference paper

Ambient filtration method to prepare paper-based electroactive nanoporous gold thin film for detection of dopamine and serotonin

Presented at the 89th Florida Annual Meeting and Exposition, Palm Harbor, FL.

By: B. Guntupalli, P. Liang, J. Dai, Y. Yang, J. He, W. Li, Y. Xiao

Event: 89th Florida Annual Meeting and Exposition at Palm Harbor, FL on May 9-11, 2013

Source: NC State University Libraries
Added: September 11, 2021

2013 speech

Bringing biosensors to the bedside

Recruitment talk presented at the Department of Chemistry, University of Tampa, Tampa, FL.

By: Y. Xiao

Event: at Department of Chemistry, University of Tampa, Tampa, FL on November 22, 2013

Source: NC State University Libraries
Added: September 11, 2021

2013 journal article

Controlling the function of DNA nanostructures with specific trigger sequences

Chem. Commun., 49(4), 397–399.

Sources: Crossref, ORCID
Added: July 11, 2021

2013 journal article

In Vitro Selection of Shape-Changing DNA Nanostructures Capable of Binding-Induced Cargo Release

ACS Nano, 7(11), 9675–9683.

By: S. Oh*, K. Plakos*, Y. Xiao, M. Eisenstein* & H. Soh*

author keywords: allostery; microfluidics; in vitro selection; functional aptamer; ATP; ATMND; structure-switching
Sources: Crossref, ORCID
Added: July 11, 2021

2013 conference paper

Paper-based single-walled carbon nanotube thin film for catalytic detection of nicotinamide adenine dinucleotide in human blood

Invited talk presented at the 89th Florida Annual Meeting and Exposition, Palm Harbor, FL.

By: Y. Xiao, J. Dai, J. Paudyal, B. Guntupalli, P. Liang, F. Pubillones, Y. Yang, W. Li, X. Wang

Event: 89th Florida Annual Meeting and Exposition at Palm Harbor, FL on May 9-11, 2013

Source: NC State University Libraries
Added: September 11, 2021

2013 journal article

Self-Assembled DNA Monolayer Buffered Dynamic Ranges of Mercuric Electrochemical Sensor

Analytical Chemistry, 85(15), 7574–7580.

By: X. Lou*, T. Zhao*, R. Liu*, J. Ma* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2012 conference paper

Biosensors, biotechnologies and biomaterials

Presented at the 9th International Symposium on Persistent Toxic Substances, Miami, FL.

By: Y. Xiao

Event: 9th International Symposium on Persistent Toxic Substances at Miami, FL on October 23-27, 2012

Source: NC State University Libraries
Added: September 11, 2021

2012 journal article

Electrochemical DNA three-way junction based sensor for distinguishing chiral metallo-supramolecular complexes

Chemical Communications, 48(55), 6900.

Sources: Crossref, ORCID
Added: July 11, 2021

2012 journal article

Selection is more intelligent than design: improving the affinity of a bivalent ligand through directed evolution

Nucleic Acids Research, 40(22), 11777–11783.

By: K. Ahmad*, Y. Xiao & H. Soh*

Sources: Crossref, ORCID
Added: July 11, 2021

2011 speech

Bringing biosensors to the bedside

Recruitment talk presented at the Department of Chemistry, Barry University, Miami, FL.

By: Y. Xiao

Event: at Department of Chemistry, Barry University, Miami, FL on November 21, 2011

Source: NC State University Libraries
Added: September 11, 2021

2011 journal article

Genetic Analysis of H1N1 Influenza Virus from Throat Swab Samples in a Microfluidic System for Point-of-Care Diagnostics

Journal of the American Chemical Society, 133(23), 9129–9135.

By: B. Ferguson*, S. Buchsbaum, T. Wu*, K. Hsieh, Y. Xiao, R. Sun*, H. Soh*

Sources: Crossref, ORCID
Added: July 11, 2021

2011 journal article

Improving Aptamer Selection Efficiency through Volume Dilution, Magnetic Concentration, and Continuous Washing in Microfluidic Channels

Analytical Chemistry, 83(17), 6883–6889.

By: S. Oh*, K. Ahmad*, M. Cho*, S. Kim*, Y. Xiao & H. Soh*

Sources: Crossref, ORCID
Added: July 11, 2021

2011 journal article

Measurement of Aptamer–Protein Interactions with Back-Scattering Interferometry

Analytical Chemistry, 83(23), 8867–8870.

By: I. Olmsted*, Y. Xiao, M. Cho*, A. Csordas*, J. Sheehan*, J. Meiler*, H. Soh*, D. Bornhop*

Sources: Crossref, ORCID
Added: July 11, 2021

2011 journal article

Polarity-Switching Electrochemical Sensor for Specific Detection of Single-Nucleotide Mismatches

Angewandte Chemie International Edition, 50(47), 11176–11180.

By: K. Hsieh*, R. White*, B. Ferguson*, K. Plaxco*, Y. Xiao & H. Soh*

author keywords: DNA; electrochemistry; sensors; single-nucleotide mismatch
Sources: Crossref, ORCID
Added: July 11, 2021

2011 journal article

Probing the Limits of Aptamer Affinity with a Microfluidic SELEX Platform

PLoS ONE, 6(11), e27051.

By: K. Ahmad*, S. Oh*, S. Kim*, F. McClellen*, Y. Xiao & H. Soh*

Ed(s): M. Antopolsky

Sources: Crossref, ORCID
Added: July 11, 2021

2011 journal article

Selection of phage-displayed peptides on live adherent cells in microfluidic channels

Proceedings of the National Academy of Sciences, 108(17), 6909–6914.

By: J. Wang*, Y. Liu, T. Teesalu, K. Sugahara, V. Kotamrajua, J. Adams, B. Ferguson, Q. Gong ...

Sources: Crossref, ORCID
Added: July 11, 2021

2011 journal article

Two-Step, PCR-Free Telomerase Detection by Using Exonuclease III-Aided Target Recycling

ChemBioChem, 12(18), 2745–2747.

By: X. Zuo*, F. Xia*, A. Patterson*, H. Soh*, Y. Xiao & K. Plaxco*

author keywords: cancer; nucleic acid detection; signal amplification; telomerase
Sources: Crossref, ORCID
Added: July 11, 2021

2010 journal article

An Electrochemical Supersandwich Assay for Sensitive and Selective DNA Detection in Complex Matrices

Journal of the American Chemical Society, 132(41), 14346–14348.

By: F. Xia*, R. White*, X. Zuo*, A. Patterson*, Y. Xiao, D. Kang*, X. Gong*, K. Plaxco*, A. Heeger*

Sources: Crossref, ORCID
Added: August 3, 2021

2010 journal article

Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes

Proceedings of the National Academy of Sciences, 107(24), 10837–10841.

By: F. Xia*, X. Zuo*, R. Yang*, Y. Xiao, D. Kang*, A. Vallee-Belisle*, X. Gong*, J. Yuen* ...

author keywords: biosensor; aptamer; visual detection; thrombin detection; cocaine detection
Sources: Crossref, ORCID
Added: August 3, 2021

2010 journal article

Detection of Proteins in Serum by Micromagnetic Aptamer PCR (MAP) Technology

Angewandte Chemie International Edition, 49(2), 355–358.

By: A. Csordas*, A. Gerdon*, J. Adams*, J. Qian*, S. Oh*, Y. Xiao, H. Soh*

author keywords: analytical methods; aptamers; growth factors; polymerase chain reaction; proteins
Sources: Crossref, ORCID
Added: August 3, 2021

2010 journal article

Detection of Telomerase Activity in High Concentration of Cell Lysates Using Primer-Modified Gold Nanoparticles

Journal of the American Chemical Society, 132(43), 15299–15307.

By: Y. Xiao, K. Dane*, T. Uzawa*, A. Csordas*, J. Qian*, H. Soh*, P. Daugherty*, E. Lagally*, A. Heeger*, K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2010 journal article

Electrochemical DNA Detection via Exonuclease and Target-Catalyzed Transformation of Surface-Bound Probes

Langmuir, 26(12), 10392–10396.

By: K. Hsieh*, Y. Xiao & H. Tom Soh*

Sources: Crossref, ORCID
Added: August 3, 2021

2010 journal article

In vitro selection of structure-switching, self-reporting aptamers

Proceedings of the National Academy of Sciences, 107(32), 14053–14058.

By: S. Oh*, K. Plakos, X. Lou, Y. Xiao & H. Soh

author keywords: G-quadruplex; systematic evolution of ligands by exponential enrichment; sensor; binding induced folding; molecular recognition
Sources: Crossref, ORCID
Added: July 11, 2021

2010 journal article

Label-Free, Dual-Analyte Electrochemical Biosensors: A New Class of Molecular-Electronic Logic Gates

Journal of the American Chemical Society, 132(25), 8557–8559.

By: F. Xia*, X. Zuo*, R. Yang*, R. White*, Y. Xiao, D. Kang*, X. Gong*, A. Lubin* ...

Sources: Crossref, ORCID
Added: July 11, 2021

2010 journal article

On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA: Electrostatic and Hydrophobic Interactions

Journal of the American Chemical Society, 132(4), 1252–1254.

By: F. Xia*, X. Zuo, R. Yang, Y. Xiao, D. Kang, A. Vallée-Bélisle, X. Gong, A. Heeger, K. Plaxco

Sources: Crossref, ORCID
Added: August 3, 2021

2010 journal article

Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing

Proceedings of the National Academy of Sciences, 107(35), 15373–15378.

By: M. Cho*, Y. Xiao, J. Nie, R. Stewart, A. Csordas, S. Oh, J. Thomson, H. Soh

author keywords: high-throughput DNA sequencing; PDGF-BB; Quantitative Selection of Aptamers through Sequencing; MicroMagnetic Separation device
Sources: Crossref, ORCID
Added: July 11, 2021

2010 journal article

Sensitive and Selective Amplified Fluorescence DNA Detection Based on Exonuclease III-Aided Target Recycling

Journal of the American Chemical Society, 132(6), 1816–1818.

By: X. Zuo*, F. Xia*, Y. Xiao & K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2010 report

Signal-on architecture for electronic oligonucleotide-based detectors

(Patent No. US7803542B2).

By: Y. Xiao, A. Lubin & K. Plaxco

Source: NC State University Libraries
Added: July 27, 2021

2009 journal article

An Electrochemical Sensor for Single Nucleotide Polymorphism Detection in Serum Based on a Triple-Stem DNA Probe

Journal of the American Chemical Society, 131(42), 15311–15316.

By: Y. Xiao, X. Lou*, T. Uzawa*, K. Plakos*, K. Plaxco* & H. Soh*

Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

Continuous, Real-Time Monitoring of Cocaine in Undiluted Blood Serum via a Microfluidic, Electrochemical Aptamer-Based Sensor

Journal of the American Chemical Society, 131(12), 4262–4266.

By: J. Swensen*, Y. Xiao, B. Ferguson*, A. Lubin*, R. Lai*, A. Heeger*, K. Plaxco*, H. Soh*

Sources: Crossref, ORCID
Added: July 11, 2021

2009 chapter

Electrochemical Approaches to Aptamer-Based Sensing

In Functional Nucleic Acids for Analytical Applications (pp. 179–197).

By: Y. Xiao & K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

Fluorescence Detection of Single-Nucleotide Polymorphisms with a Single, Self-Complementary, Triple-Stem DNA Probe

Angewandte Chemie International Edition, 48(24), 4354–4358.

By: Y. Xiao, K. Plakos*, X. Lou*, R. White*, J. Qian*, K. Plaxco*, H. Soh*

author keywords: DNA; fluorescent probes; self-complementary sequences; single-nucleotide polymorphisms
Sources: Crossref, ORCID
Added: August 3, 2021

2009 journal article

Generation of Highly Specific Aptamers via Micromagnetic Selection

Analytical Chemistry, 81(13), 5490–5495.

By: J. Qian*, X. Lou*, Y. Zhang*, Y. Xiao & H. Soh*

Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

High Specificity, Electrochemical Sandwich Assays Based on Single Aptamer Sequences and Suitable for the Direct Detection of Small-Molecule Targets in Blood and Other Complex Matrices

Journal of the American Chemical Society, 131(20), 6944–6945.

By: X. Zuo*, Y. Xiao & K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

Label-Free Colorimetric Screening of Nuclease Activity and Substrates by Using Unmodified Gold Nanoparticles

ChemBioChem, 10(12), 1973–1977.

By: X. Lou*, Y. Xiao, Y. Wang*, H. Mao* & J. Zhao*

author keywords: high-throughput screening; nanoparticles; nucleases; nucleoside monophosphates; substrate selectivity
Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

Micromagnetic selection of aptamers in microfluidic channels

Proceedings of the National Academy of Sciences, 106(9), 2989–2994.

By: X. Lou*, J. Qian, Y. Xiao, L. Viel, A. Gerdon, E. Lagally, P. Atzberger, T. Tarasow, A. Heeger, H. Soh

author keywords: microchannel; recombinant Botulinum neurotoxin type A; systematic evolution of ligands by exponential enrichment
Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

On the Signaling of Electrochemical Aptamer-Based Sensors: Collision- and Folding-Based Mechanisms

Electroanalysis, 21(11), 1267–1271.

author keywords: Aptamer-based sensors; Folding and unfolding; Biosensors; Aptamers; Thrombin; IgE
Sources: Crossref, ORCID
Added: July 11, 2021

2009 journal article

i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon Nanotubes

Journal of the American Chemical Society, 131(38), 13813–13818.

By: Y. Peng*, X. Wang*, Y. Xiao, L. Feng*, C. Zhao*, J. Ren*, X. Qu*

Sources: Crossref, ORCID
Added: July 11, 2021

2008 journal article

Optimization of Electrochemical Aptamer-Based Sensors via Optimization of Probe Packing Density and Surface Chemistry

Langmuir, 24(18), 10513–10518.

By: R. White*, N. Phares*, A. Lubin*, Y. Xiao & K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2008 journal article

Optimization of a Reusable, DNA Pseudoknot-Based Electrochemical Sensor for Sequence-Specific DNA Detection in Blood Serum

Analytical Chemistry, 81(2), 656–661.

By: K. Cash*, A. Heeger*, K. Plaxco* & Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2007 report

Catalytic polynucleotide and its use for determination of analytes

(US Patent No. 20070254282).

By: I. Willner, Y. Xiao, V. Pavlov & T. Niazov

Source: NC State University Libraries
Added: September 11, 2021

2007 journal article

Electrochemical Detection of Parts-Per-Billion Lead via an Electrode-Bound DNAzyme Assembly

Journal of the American Chemical Society, 129(2), 262–263.

By: Y. Xiao, A. Rowe* & K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2007 journal article

Label-Free Electrochemical Detection of DNA in Blood Serum via Target-Induced Resolution of an Electrode-Bound DNA Pseudoknot

Journal of the American Chemical Society, 129(39), 11896–11897.

By: Y. Xiao, X. Qu*, K. Plaxco* & A. Heeger*

Sources: Crossref, ORCID
Added: July 11, 2021

2007 journal article

Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing

Nature Protocols, 2(11), 2875–2880.

By: Y. Xiao, R. Lai* & K. Plaxco*

Sources: Crossref, ORCID
Added: July 11, 2021

2006 chapter

Catalytic Beacons for the Detection of DNA and Telomerase Activity

In D. Morrison, F. Milanovich, D. Ivnitski, & T. R. Austin (Eds.), Defense against Bioterror (pp. 199–205).

By: Y. Xiao, V. Pavlov, T. Niazov, A. Dishon, M. Kotler & I. Willner

Ed(s): D. Morrison, F. Milanovich, D. Ivnitski & T. Austin

Sources: Crossref, ORCID
Added: August 3, 2021

2006 report

Novel sensors with nanoparticle probe

(Patent Application No. WO2006008742).

By: I. Willner, V. Pavlov, M. Zayatz, T. Niazov, B. Shlyahovsky, Y. Xiao, R. Buron

Source: NC State University Libraries
Added: September 11, 2021

2006 journal article

Single-step electronic detection of femtomolar DNA by target-induced strand displacement in an electrode-bound duplex

Proceedings of the National Academy of Sciences, 103(45), 16677–16680.

By: Y. Xiao, A. Lubin, B. Baker, K. Plaxco & A. Heeger

author keywords: biosensors; electron transfer; gold electrode; methylene blue; signal-on
Sources: Crossref, ORCID
Added: July 11, 2021

2005 journal article

A Reagentless Signal-On Architecture for Electronic, Aptamer-Based Sensors via Target-Induced Strand Displacement

Journal of the American Chemical Society, 127(51), 17990–17991.

By: Y. Xiao, B. Piorek*, K. Plaxco* & A. Heeger*

Sources: Crossref, ORCID
Added: July 11, 2021

2005 journal article

An OsII-Bisbipyridine-4-Picolinic Acid Complex Mediates the Biocatalytic Growth of Au Nanoparticles: Optical Detection of Glucose and Acetylcholine Esterase Inhibition

Chemistry - A European Journal, 11(9), 2698–2704.

By: Y. Xiao, V. Pavlov*, B. Shlyahovsky* & I. Willner*

author keywords: enzymes; gold; inhibitors; nanotechnology; sensors
Sources: Crossref, ORCID
Added: July 11, 2021

2005 journal article

Inhibition of the Acetycholine Esterase-Stimulated Growth of Au Nanoparticles:  Nanotechnology-Based Sensing of Nerve Gases

Nano Letters, 5(4), 649–653.

By: V. Pavlov*, Y. Xiao & I. Willner*

Sources: Crossref, ORCID
Added: July 11, 2021

2005 journal article

Label-Free Electronic Detection of Thrombin in Blood Serum by Using an Aptamer-Based Sensor

Angewandte Chemie International Edition, 44(34), 5456–5459.

By: Y. Xiao, A. Lubin*, A. Heeger* & K. Plaxco*

author keywords: aptamers; biosensors; DNA structures; electron transfer; thrombin
Sources: Crossref, ORCID
Added: August 3, 2021

2005 journal article

Optical and Electrochemical Detection of NADH and of NAD+-Dependent Biocatalyzed Processes by the Catalytic Deposition of Copper on Gold Nanoparticles

Small, 1(2), 213–216.

By: B. Shlyahovsky*, E. Katz*, Y. Xiao, V. Pavlov* & I. Willner*

author keywords: copper; enzymes; gold; nanoparticles; sensors
Sources: Crossref, ORCID
Added: July 11, 2021

2005 journal article

Shape and color of Au nanoparticles follow biocatalytic processes

Langmuir, 21(13), 5659–5662.

By: Y. Xiao, B. Shlyahovsky, I. Popov, V. Pavlov & I. Willner

Sources: Web Of Science, ORCID
Added: August 7, 2021

2004 journal article

Amplified Chemiluminescence Surface Detection of DNA and Telomerase Activity Using Catalytic Nucleic Acid Labels

Analytical Chemistry, 76(7), 2152–2156.

By: V. Pavlov*, Y. Xiao, R. Gill*, A. Dishon*, M. Kotler* & I. Willner*

Sources: Crossref, ORCID
Added: July 11, 2021

2004 journal article

Aptamer-Functionalized Au Nanoparticles for the Amplified Optical Detection of Thrombin

Journal of the American Chemical Society, 126(38), 11768–11769.

By: V. Pavlov*, Y. Xiao, B. Shlyahovsky* & I. Willner*

Sources: Crossref, ORCID
Added: July 11, 2021

2004 journal article

Catalytic Beacons for the Detection of DNA and Telomerase Activity

Journal of the American Chemical Society, 126(24), 7430–7431.

By: Y. Xiao, V. Pavlov*, T. Niazov*, A. Dishon*, M. Kotler* & I. Willner*

Sources: Crossref, ORCID
Added: July 11, 2021

2004 journal article

Catalytic Growth of Au Nanoparticles by NAD(P)H Cofactors: Optical Sensors for NAD(P)+-Dependent Biocatalyzed Transformations

Angewandte Chemie International Edition, 43(34), 4519–4522.

By: Y. Xiao, V. Pavlov*, S. Levine*, T. Niazov*, G. Markovitch* & I. Willner*

author keywords: biosensors; cofactors; enzymes; gold; nanostructures
Sources: Crossref, ORCID
Added: July 11, 2021

2004 journal article

DNAzyme-Functionalized Au Nanoparticles for the Amplified Detection of DNA or Telomerase Activity

Nano Letters, 4(9), 1683–1687.

By: T. Niazov*, V. Pavlov*, Y. Xiao, R. Gill* & I. Willner*

Sources: Crossref, ORCID
Added: July 11, 2021

2004 journal article

Electrical contacting of glucose oxidase by DNA-templated polyaniline wires on surfaces

Electrochemistry Communications, 6(10), 1057–1060.

By: L. Shi*, Y. Xiao & I. Willner*

author keywords: poly(aniline-aniline boronic acid) wires; DNA template; apo-glucose oxidase; reconstitution; biosensor
Sources: Crossref, ORCID
Added: July 11, 2021

2004 journal article

Lighting Up Biochemiluminescence by the Surface Self-Assembly of DNA-Hemin Complexes

ChemBioChem, 5(3), 374–379.

By: Y. Xiao, V. Pavlov*, R. Gill*, T. Bourenko* & I. Willner*

author keywords: biocatalysis; DNA; hemin; luminescence; monolayers; self-assembly
Sources: Crossref, ORCID
Added: August 3, 2021

2003 journal article

"Plugging into Enzymes": Nanowiring of Redox Enzymes by a Gold Nanoparticle

Science, 299(5614), 1877–1881.

By: Y. Xiao

Sources: Crossref, ORCID
Added: July 11, 2021

2003 journal article

Electrocatalytic intercalator-induced winding of double-stranded DNA with polyaniline

Chemical Communications, (13), 1540.

By: Y. Xiao, A. Kharitonov*, F. Patolsky*, Y. Weizmann* & I. Willner*

Sources: Crossref, ORCID
Added: July 11, 2021

2002 journal article

Electrooxidative coupling of a toluidine blue O terminated self-assembled monolayer studied by electrochemistry and surface enhanced Raman spectroscopy

Journal of Electroanalytical Chemistry, 518(2), 123–130.

By: H. Ju*, Y. Xiao, X. Lu* & H. Chen*

author keywords: chemically modified electrode; surface enhanced Raman spectroscopy; electropolymerization; monolayers; toluidine blue O; electrooxidative coupling
Sources: Crossref, ORCID
Added: July 11, 2021

2001 journal article

Anion adsorption on an Au colloid monolayer based cysteamine-modified gold electrode

Chemical Research in Chinese Universities, 17(2), 159–167.

By: X. Hu, Y. Xiao & H. Chen

Source: NC State University Libraries
Added: September 11, 2021

2000 journal article

Direct Electrochemistry of Horseradish Peroxidase Immobilized on a Colloid/Cysteamine-Modified Gold Electrode

Analytical Biochemistry, 278(1), 22–28.

By: X. Yi*, J. Huang-Xian* & C. Hong-Yuan*

author keywords: horseradish peroxidase; direct electrochemistry; Au colloid; cysteamine; biosensor; self-assembled monolayers
Sources: Crossref, ORCID
Added: August 3, 2021

1999 journal article

A reagentless hydrogen peroxide sensor based on incorporation of horseradish peroxidase in poly(thionine) film on a monolayer modified electrode

Analytica Chimica Acta, 391(3), 299–306.

By: Y. Xiao, H. Ju* & H. Chen*

author keywords: hydrogen peroxide sensor; poly(thionine) film; coimmobilization; horseradish peroxidase; thionine monolayer; gold electrode
Sources: Crossref, ORCID
Added: July 11, 2021

1999 journal article

Adsorption characteristics of Fe(CN)63−/4− on Au colloids as monolayer films on cysteamine-modified gold electrode

Journal of Electroanalytical Chemistry, 466(1), 26–30.

By: X. Hu*, Y. Xiao & H. Chen*

author keywords: colloidal gold; self-assembled monolayers; gold electrode
Sources: Crossref, ORCID
Added: July 11, 2021

1999 journal article

Hydrogen peroxide sensor based on horseradish peroxidase-labeled Au colloids immobilized on gold electrode surface by cysteamine monolayer

Analytica Chimica Acta, 391(1), 73–82.

By: Y. Xiao, H. Ju* & H. Chen*

author keywords: self-assembled monolayers; HRP-labeled Au colloids; cysteamine; hydrogen peroxide; sensors; electrochemical sensors
Sources: Crossref, ORCID
Added: July 11, 2021

1998 journal article

Amperometric Biosensor for Glucose Based on a Nanometer-Sized Microband Gold Electrode Coimmobilized with Glucose Oxidase and Poly(o-phenylenediamide)

Electroanalysis, 10(8), 541–545.

By: H. Ju*, D. Zhou*, Y. Xiao & H. Chen*

author keywords: glucose sensors; nanometer-sized biosensors; o-phenylenediamide; glucose oxidase; electrochemical polymerization; microband gold electrodes
Sources: Crossref, ORCID
Added: July 11, 2021

Employment

Updated: October 26th, 2021 22:06

2021 - present

North Carolina State University Raleigh, NC, US
Department of Chemistry

2011 - 2021

Florida International University MIAMI, FL, US
Associate Professor Chemistry and Biochemistry