Yiyun Zhang

Works (1)

Updated: July 5th, 2023 15:43

2013 article

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

Lin, J., Countryman, P., Buncher, N., Kaur, P., Longjiang, E., Zhang, Y., … Wang, H. (2013, November 22). Nucleic Acids Research, Vol. 42, pp. 2493–2504.

By: J. Lin n, P. Countryman n, N. Buncher  n, P. Kaur n, E. Longjiang n, Y. Zhang n, G. Gibson  n, C. You  n ...

MeSH headings : DNA / chemistry; DNA / metabolism; Diffusion; Protein Binding; Protein Structure, Tertiary; Repetitive Sequences, Nucleic Acid; Telomere / chemistry; Telomere / metabolism; Telomeric Repeat Binding Protein 1 / metabolism; Telomeric Repeat Binding Protein 2 / chemistry; Telomeric Repeat Binding Protein 2 / metabolism
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; CRISPR and Genetic Engineering; Genomics and Chromatin Dynamics
TL;DR: It is proposed that the TRF proteins use 1D sliding to find protein partners and assemble the shelterin complex, which in turn stabilizes the interaction with specific telomeric DNA. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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