Works (6)

Updated: July 5th, 2023 15:37

2023 journal article

Metabolic engineering of the anthocyanin biosynthetic pathway in Artemisia annua and relation to the expression of the artemisinin biosynthetic pathway

PLANTA, 257(3).

By: R. Judd n, Y. Dong n, X. Sun n, Y. Zhu n, M. Li n & D. Xie n

author keywords: Anthocyanin; Artemisinin; Artemisinic acid; Arteannuin b; Artemisia annua; Plant tissue culture
MeSH headings : Artemisia annua / chemistry; Anthocyanins / metabolism; Biosynthetic Pathways; Metabolic Engineering; Reactive Oxygen Species / metabolism; Tandem Mass Spectrometry; Artemisinins / chemistry; Artemisinins / metabolism
Sources: Web Of Science, ORCID
Added: February 24, 2023

2022 journal article

Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E

VIROLOGY, 571, 21–33.

By: Y. Zhu n, F. Scholle n, S. Kisthardt n & D. Xie n

author keywords: (+)-dihydrokaempferol; <p>(+)-dihydroquercetin (taxifolin)</p>; (+)-dihydromyricetin; Kaempferol; Quercetin; Myricentin; Isoquercitrin; Rutin; Flavan-3-ols
MeSH headings : COVID-19; Coronavirus 229E, Human / drug effects; Coronavirus 229E, Human / physiology; Coronavirus 3C Proteases / antagonists & inhibitors; Flavonols / pharmacology; Humans; Molecular Docking Simulation; SARS-CoV-2 / drug effects; Virus Replication / drug effects
Sources: Web Of Science, ORCID
Added: May 23, 2022

2022 journal article

A de novo regulation design shows an effectiveness in altering plant secondary metabolism


By: M. Li n, X. He n, C. La Hovary n, Y. Zhu n, Y. Dong n, S. Liu n, H. Xing n, Y. Liu n ...

author keywords: Arabidopsis; Alkaloid; Anthocyanin; Molecular tools; Tobacco; Transcription factor
MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Gene Expression Regulation, Plant; Nicotine / metabolism; Pancreatitis-Associated Proteins / genetics; Pancreatitis-Associated Proteins / metabolism; Secondary Metabolism / genetics
Sources: Web Of Science, ORCID
Added: January 26, 2022

2020 journal article

Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2

Frontiers in Plant Science, 11.

By: Y. Zhu n & D. Xie n

author keywords: flavan-3-ols; flavan-3-ol gallates; procyanidins; COVID-19; green tea; muscadine grape; cacao; dark chocolate
Sources: Crossref, ORCID
Added: December 1, 2020

2017 journal article

Overexpression and Suppression of Artemisia annua 4-Hydroxy-3-Methylbut-2-enyl Diphosphate Reductase 1 Gene (AaHDR1) Differentially Regulate Artemisinin and Terpenoid Biosynthesis


By: D. Ma n, G. Li n, Y. Zhu n & D. Xie n

author keywords: Artemisia annua; artemisinin; arteannuin B; 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; methylerythritol phosphate pathway; terpene
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Overexpression of a type-I isopentenyl pyrophosphate isomerase of Artemisia annua in the cytosol leads to high arteannuinB production and artemisinin increase

Plant Journal, 91(3), 466–479.

By: D. Ma n, G. Li n, F. Alejos-Gonzalez n, Y. Zhu n, Z. Xue*, A. Wang*, H. Zhang*, X. Li* ...

MeSH headings : Artemisia annua / enzymology; Artemisia annua / genetics; Artemisia annua / metabolism; Artemisinins / metabolism; Carbon-Carbon Double Bond Isomerases / genetics; Carbon-Carbon Double Bond Isomerases / metabolism; Cytosol / enzymology; Cytosol / metabolism; Hemiterpenes; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified / enzymology; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism
Sources: NC State University Libraries, ORCID
Added: August 6, 2018