Maternal Autogenous Inactivated Virus Vaccination Boosts Immunity to PRRSV in Piglets
Kick, A. R., Wolfe, Z. C., Amaral, A. F., Cortes, L. M., Almond, G. W., Crisci, E., … Käser, T. (2021, January 31). Vaccines, Vol. 9, p. 106.
author keywords: maternal vaccination; autogenous inactivated vaccine; transfer of immunity; humoral immune response; cell-mediated immune response; T cells; PRRSV; swine; IFN-gamma producing B cells; CD4 T-EMRA cells
topics (OpenAlex): Animal Virus Infections Studies; Viral gastroenteritis research and epidemiology; Virus-based gene therapy research
TL;DR:
It is demonstrated that maternal AIV vaccination can improve protection of pre-weaning piglets against PRRSV-2 and shows the importance of transferring neutralizing antibodies to piglets, and it introduces two novel immune cell subsets in pigs—IFN-γ producing CD21α+ B cells and CD8α−CCR7− CD4 T cells.
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