Zhen Gu

Li, H., Wang, Z., Archibong, E., Wu, Q., Chen, G., Hu, Q., … Gu, Z. (2022). Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy. NATIONAL SCIENCE REVIEW, 9(3). https://doi.org/10.1093/nsr/nwab172

Chen, Z., Li, H., Bian, Y., Wang, Z., Chen, G., Zhang, X., … Gu, Z. (2021, May 10). Bioorthogonal catalytic patch. NATURE NANOTECHNOLOGY. https://doi.org/10.1038/s41565-021-00910-7

Hu, Q., Li, H., Archibong, E., Chen, Q., Ruan, H., Ahn, S., … Gu, Z. (2021, April 26). Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets. NATURE BIOMEDICAL ENGINEERING. https://doi.org/10.1038/s41551-021-00712-1

Paul, R., Ostermann, E., Chen, Y., Saville, A. C., Yang, Y., Gu, Z., … Wei, Q. (2021). Integrated microneedle-smartphone nucleic acid amplification platform for in-field diagnosis of plant diseases. BIOSENSORS & BIOELECTRONICS, 187. https://doi.org/10.1016/j.bios.2021.113312

Sun, W., Wang, J., Hu, Q., Zhou, X., Khademhosseini, A., & Gu, Z. (2020). CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation. SCIENCE ADVANCES, 6(21). https://doi.org/10.1126/sciadv.aba2983

Zhang, X., Kang, Y., Wang, J., Yan, J., Chen, Q., Cheng, H., … Gu, Z. (2020). Engineered PD-L1-Expressing Platelets Reverse New-Onset Type 1 Diabetes. ADVANCED MATERIALS, 32(26). https://doi.org/10.1002/adma.201907692

Yu, J., Wang, J., Zhang, Y., Chen, G., Mao, W., Ye, Y., … Gu, Z. (2020). Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs. NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506. https://doi.org/10.1038/s41551-019-0508-y

Lee, K. J., Goudie, M. J., Tebon, P., Sun, W., Luo, Z., Lee, J., … Khademhosseini, A. (2020). [Review of Non-transdermal microneedles for advanced drug delivery]. ADVANCED DRUG DELIVERY REVIEWS, 165-166, 41–59. https://doi.org/10.1016/j.addr.2019.11.010

Richter, L. R., Wan, Q., Wen, D., Zhang, Y., Yu, J., Kang, J. K., … Pajvani, U. B. (2020). Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis. ACS NANO, 14(6), 6878–6886. https://doi.org/10.1021/acsnano.0c01007

Ruan, H., Hu, Q., Wen, D., Chen, Q., Chen, G., Lu, Y., … Gu, Z. (2019). A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade. ADVANCED MATERIALS, 31(17). https://doi.org/10.1002/adma.201806957

Yang, G., Chen, Q., Wen, D., Chen, Z., Wang, J., Chen, G., … Gu, Z. (2019). A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth. ACS NANO, 13(4), 4354–4360. https://doi.org/10.1021/acsnano.8b09573

Wang, J., Wang, Z., Yu, J., Zhang, Y., Zeng, Y., & Gu, Z. (2019). A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery. BIOMATERIALS SCIENCE, 7(11), 4508–4513. https://doi.org/10.1039/c9bm01283d

Wen, D., Wang, J., Van Den Driessche, G., Chen, Q., Zhang, Y., Chen, G., … Gu, Z. (2019). Adipocytes as Anticancer Drug Delivery Depot. MATTER, 1(5), 1203–1214. https://doi.org/10.1016/j.matt.2019.08.007

Bu, L.-L., Yan, J., Wang, Z., Ruan, H., Chen, Q., Gunadhi, V., … Gu, Z. (2019). Advances in drug delivery for post-surgical cancer treatment. Biomaterials, 219, 119182. https://doi.org/10.1016/J.BIOMATERIALS.2019.04.027

Zhang, Y., Yu, J., Kahkoska, A. R., Wang, J., Buse, J. B., & Gu, Z. (2019). [Review of Advances in transdermal insulin delivery]. ADVANCED DRUG DELIVERY REVIEWS, 139, 51–70. https://doi.org/10.1016/j.addr.2018.12.006

Chen, Q., Chen, G., Chen, J., Shen, J., Zhang, X., Wang, J., … Gu, Z. (2019). Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy. NANO LETTERS, 19(8), 4879–4889. https://doi.org/10.1021/acs.nanolett.9b00584

Bu, L.-L., Rao, L., Yu, G.-T., Chen, L., Deng, W.-W., Liu, J.-F., … Sun, Z.-J. (2019). Cancer Stem Cell-Platelet Hybrid Membrane-Coated Magnetic Nanoparticles for Enhanced Photothermal Therapy of Head and Neck Squamous Cell Carcinoma. Advanced Functional Materials, 29(10), 1807733. https://doi.org/10.1002/ADFM.201807733

Wang, J., Yu, J., Zhang, Y., Zhang, X., Kahkoska, A. R., Chen, G., … Gu, Z. (2019). Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs. SCIENCE ADVANCES, 5(7). https://doi.org/10.1126/sciadv.aaw4357

Yang, G., Lu, Y., Bomba, H. N., & Gu, Z. (2019). [Review of Cysteine-rich Proteins for Drug Delivery and Diagnosis]. CURRENT MEDICINAL CHEMISTRY, 26(8), 1377–1388. https://doi.org/10.2174/0929867324666170920163156

Ruan, H., Hu, Q., Wen, D., Chen, Q., Chen, G., Lu, Y., … Gu, Z. (2019). Drug Delivery: A Dual‐Bioresponsive Drug‐Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade (Adv. Mater. 17/2019). Advanced Materials, 31(17), 1970120. https://doi.org/10.1002/ADMA.201970120

Wen, D., Chen, G., Chen, Q., Li, P. Y., Cheng, H., & Gu, Z. (2019). Engineering Protein Delivery Depots for Cancer Immunotherapy. Bioconjugate Chemistry, 30(3), 515–524. https://doi.org/10.1021/ACS.BIOCONJCHEM.9B00061

Yu, S., Wei, S., Liu, L., Qi, D., Wang, J., Chen, G., … Gu, Z. (2019). Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot. BIOMATERIALS SCIENCE, 7(3), 860–866. https://doi.org/10.1039/c8bm01442f

Paul, R., Saville, A. C., Hansel, J. C., Ye, Y., Ball, C., Williams, A., … Wei, Q. (2019). Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases. ACS Nano, 13(6), 6540–6549. https://doi.org/10.1021/acsnano.9b00193

Wang, J., Yu, J., Zhang, Y., Kahkoska, A. R., Wang, Z., Fang, J., … Gu, Z. (2019). Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(22), 10744–10748. https://doi.org/10.1073/pnas.1901967116

Chen, Q., Wang, C., Zhang, X., Chen, G., Hu, Q., Li, H., … Gu, Z. (2019). In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment. NATURE NANOTECHNOLOGY, 14(1), 89-+. https://doi.org/10.1038/s41565-018-0319-4

Chen, Q., Hu, Q., Dukhovlinova, E., Chen, G., Ahn, S., Wang, C., … Gu, Z. (2019). Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells. ADVANCED MATERIALS, 31(23). https://doi.org/10.1002/adma.201900192

Lu, Y., Hu, Q., Jiang, C., & Gu, Z. (2019). Platelet for drug delivery. Current Opinion in Biotechnology, 58, 81–91. https://doi.org/10.1016/J.COPBIO.2018.11.010

Yan, J., Zhang, X., Liu, Y., Ye, Y., Yu, J., Chen, Q., … Gu, Z. (2019). Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy. NANO RESEARCH, 12(6), 1313–1320. https://doi.org/10.1007/s12274-018-2262-y

Ye, Y., Wang, J., Sun, W., Bomba, H. N., & Gu, Z. (2019). Topical and Transdermal Nanomedicines for Cancer Therapy. NANOTHERANOSTICS FOR CANCER APPLICATIONS, Vol. 5, pp. 231–251. https://doi.org/10.1007/978-3-030-01775-0_10

Luo, J., Meng, J., Gu, Z., Wang, L., Zhang, F., & Wang, S. (2019). Topography‐Induced Cell Self‐Organization from Simple to Complex Aggregates. Small, 15(15), 1900030. https://doi.org/10.1002/SMLL.201900030

Yu, J., Zhang, Y., Yan, J., Kahkoska, A. R., & Gu, Z. (2018). Advances in bioresponsive closed-loop drug delivery systems. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 544(2), 350–357. https://doi.org/10.1016/j.ijpharm.2017.11.064

Cai, L., Gu, Z., Zhong, J., Wen, D., Chen, G., He, L., … Gu, Z. (2018). [Review of Advances in glycosylation-mediated cancer-targeted drug delivery]. DRUG DISCOVERY TODAY, 23(5), 1126–1138. https://doi.org/10.1016/j.drudis.2018.02.009

Yan, J., Lu, Y., Chen, G., Yang, M., & Gu, Z. (2018). [Review of Advances in liquid metals for biomedical applications]. CHEMICAL SOCIETY REVIEWS, 47(8), 2518–2533. https://doi.org/10.1039/c7cs00309a

Hu, Q., Chen, Q., & Gu, Z. (2018). Advances in transformable drug delivery systems. BIOMATERIALS, 178, 546–558. https://doi.org/10.1016/j.biomaterials.2018.03.056

Chen, W., Wang, Y., Qin, M., Zhang, X., Zhang, Z., Sun, X., & Gu, Z. (2018). Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy. ACS NANO, 12(6), 5995–6005. https://doi.org/10.1021/acsnano.8b02235

Luo, Z., Sun, W., Fang, J., Lee, K. J., Li, S., Gu, Z., … Khademhosseini, A. (2018). Biodegradable Gelatin Methacryloyl Microneedles for Transdermal Drug Delivery. Advanced Healthcare Materials, 8(3), 1801054. https://doi.org/10.1002/ADHM.201801054

Zhang, Y., Wang, J., Yu, J., Wen, D., Kahkoska, A. R., Lu, Y., … Gu, Z. (2018). Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery. SMALL, 14(14). https://doi.org/10.1002/smll.201704181

Xue, P., Zhang, L., Xu, Z., Yan, J., Gu, Z., & Kang, Y. (2018). [Review of Blood sampling using microneedles as a minimally invasive platform for biomedical diagnostics]. APPLIED MATERIALS TODAY, 13, 144–157. https://doi.org/10.1016/j.apmt.2018.08.013

Zhang, X., Wang, C., Wang, J., Hu, Q., Langworthy, B., Ye, Y., … Gu, Z. (2018). Cancer Immunotherapy: PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy (Adv. Mater. 22/2018). Advanced Materials, 30(22), 1870152. https://doi.org/10.1002/ADMA.201870152

Tang, J., Wang, J., Huang, K., Ye, Y., Su, T., Qiao, L., … Cheng, K. (2018). Cardiac cell-integrated microneedle patch for treating myocardial infarction. SCIENCE ADVANCES, 4(11). https://doi.org/10.1126/sciadv.aat9365

Fan, Y.-N., Li, M., Luo, Y.-L., Chen, Q., Wang, L., Zhang, H.-B., … Wang, J. (2018). Cationic lipid-assisted nanoparticles for delivery of mRNA cancer vaccine. Biomaterials Science, 6(11), 3009–3018. https://doi.org/10.1039/C8BM00908B

Wang, C., Wen, D., & Gu, Z. (2018). [Review of Cellular Bioparticulates with Therapeutics for Cancer Immunotherapy]. BIOCONJUGATE CHEMISTRY, 29(3), 702–708. https://doi.org/10.1021/acs.bioconjchem.7b00619

Hu, Q., Sun, W., Wang, J., Ruan, H., Zhang, X., Ye, Y., … Gu, Z. (2018). Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy. NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840. https://doi.org/10.1038/s41551-018-0310-2

Wang, J., Ye, Y., Yu, J., Kahkoska, A. R., Zhang, X., Wang, C., … Gu, Z. (2018). Core–Shell Microneedle Gel for Self-Regulated Insulin Delivery. ACS Nano, 12(3), 2466–2473. https://doi.org/10.1021/ACSNANO.7B08152

Chen, Q., Wang, C., Chen, G., Hu, Q., & Gu, Z. (2018). Delivery Strategies for Immune Checkpoint Blockade. ADVANCED HEALTHCARE MATERIALS, 7(20). https://doi.org/10.1002/adhm.201800424

Ji, Y., Xiao, Y., Xu, L., He, J., Qian, C., Li, W., … Chen, Z. (2018). Drug-Bearing Supramolecular MMP Inhibitor Nanofibers for Inhibition of Metastasis and Growth of Liver Cancer. Advanced Science, 5(8), 1700867. https://doi.org/10.1002/ADVS.201700867

Zhang, X., Wang, J., Chen, Z., Hu, Q., Wang, C., Yan, J., … Gu, Z. (2018). Engineering PD-1-Presenting Platelets for Cancer Immunotherapy. NANO LETTERS, 18(9), 5716–5725. https://doi.org/10.1021/acs.nanolett.8b02321

Bakh, N. A., Cortinas, A. B., Weiss, M. A., Langer, R. S., Anderson, D. G., Gu, Z., … Strano, M. S. (2018, January). Glucose-responsive insulin by molecular and physical design (vol 9, pg 937, 2017). NATURE CHEMISTRY, Vol. 10, pp. 109–109. https://doi.org/10.1038/nchem.2898

Yu, J., Zhang, Y., Wang, J., Wen, D., Kahkoska, A. R., Buse, J. B., & Gu, Z. (2018). Glucose-responsive oral insulin delivery for postprandial glycemic regulation. Nano Research, 12(7), 1539–1545. https://doi.org/10.1007/S12274-018-2264-9

Liu, M., Shen, S., Wen, D., Li, M., Li, T., Chen, X., … Mo, R. (2018). Hierarchical Nanoassemblies-Assisted Combinational Delivery of Cytotoxic Protein and Antibiotic for Cancer Treatment. NANO LETTERS, 18(4), 2294–2303. https://doi.org/10.1021/acs.nanolett.7b04976

Wang, C., Wang, J., Zhang, X., Yu, S., Wen, D., Hu, Q., … Gu, Z. (2018). In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy. SCIENCE TRANSLATIONAL MEDICINE, 10(429). https://doi.org/10.1126/scitranslmed.aan3682

Yu, S., Wang, C., Yu, J., Wang, J., Lu, Y., Zhang, Y., … Gu, Z. (2018). Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade. Advanced Materials, 30(28), 1801527. https://doi.org/10.1002/ADMA.201801527

Gu, Z. (2018). Leverage physiology for precision medications. Nanomedicine: Nanotechnology, Biology and Medicine, 14(5), 1883–1884. https://doi.org/10.1016/J.NANO.2017.11.378

Chen, Z., Hu, Q., & Gu, Z. (2018). [Review of Leveraging Engineering of Cells for Drug Delivery]. ACCOUNTS OF CHEMICAL RESEARCH, 51(3), 668–677. https://doi.org/10.1021/acs.accounts.7b00526

Zhao, P., Jin, Z., Chen, Q., Yang, T., Chen, D., Meng, J., … He, Q. (2018). Local generation of hydrogen for enhanced photothermal therapy. Nature Communications, 9(1). https://doi.org/10.1038/S41467-018-06630-2

Luo, Y.-L., Xu, C.-F., Li, H.-J., Cao, Z.-T., Liu, J., Wang, J.-L., … Wang, J. (2018). Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles. ACS NANO, 12(2), 994–1005. https://doi.org/10.1021/acsnano.7b07874

Zhang, Y., Yu, J., Qiang, L., & Gu, Z. (2018). Nanomedicine for obesity treatment. Science China Life Sciences, 61(4), 373–379. https://doi.org/10.1007/S11427-017-9257-1

Zhang, X., Wang, C., Wang, J., Hu, Q., Langworthy, B., Ye, Y., … Gu, Z. (2018). PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy. ADVANCED MATERIALS, 30(22). https://doi.org/10.1002/adma.201707112

Wu, L., Cai, X., Zhu, H., Li, J., Shi, D., Su, D., … Gu, Z. (2018). PDT-Driven Highly Efficient Intracellular Delivery and Controlled Release of CO in Combination with Sufficient Singlet Oxygen Production for Synergistic Anticancer Therapy. Advanced Functional Materials, 28(41), 1804324. https://doi.org/10.1002/ADFM.201804324

Ye, Y., Yu, J., Wen, D., Kahkoska, A. R., & Gu, Z. (2018). [Review of Polymeric microneedles for transdermal protein delivery]. ADVANCED DRUG DELIVERY REVIEWS, 127, 106–118. https://doi.org/10.1016/j.addr.2018.01.015

Zhang, Y., Feng, P., Yu, J., Yang, J., Zhao, J., Wang, J., … Gu, Z. (2018). ROS-Responsive Microneedle Patch for Acne Vulgaris Treatment. Advanced Therapeutics, 1(3), 1800035. https://doi.org/10.1002/ADTP.201800035

Zhang, Y., Feng, P., Yu, J., Yang, J., Zhao, J., Wang, J., … Gu, Z. (2018). ROS-Responsive Microneedle Patch for Acne Vulgaris Treatment (Adv. Therap. 3/2018). Advanced Therapeutics, 1(3), 1870006. https://doi.org/10.1002/ADTP.201870006

Ruan, H., Bu, L., Hu, Q., Cheng, H., Lu, W., & Gu, Z. (2018). Strategies of Combination Drug Delivery for Immune Checkpoint Blockades. Advanced Healthcare Materials, 1801099. https://doi.org/10.1002/ADHM.201801099

Tang, J., Su, T., Huang, K., Dinh, P.-U., Wang, Z., Vandergriff, A., … Cheng, K. (2018). Targeted repair of heart injury by stem cells fused with platelet nanovesicles. NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26. https://doi.org/10.1038/s41551-017-0182-x

Xu, C., Lu, Z., Luo, Y., Liu, Y., Cao, Z., Shen, S., … Wang, J. (2018). Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases. Nature Communications, 9(1). https://doi.org/10.1038/S41467-018-06522-5

Zhang, Y., Yu, J., Wen, D., Chen, G., & Gu, Z. (2018). The potential of a microneedle patch for reducing obesity. EXPERT OPINION ON DRUG DELIVERY, Vol. 15, pp. 431–433. https://doi.org/10.1080/17425247.2018.1449831

Gu, Z., & Chen, X. (2018, March 1). Towards Enhancing Skin Drug Delivery. ADVANCED DRUG DELIVERY REVIEWS, Vol. 127, pp. 1–2. https://doi.org/10.1016/j.addr.2018.05.004

Ye, Y., Wang, C., Zhang, X., Hu, Q., Zhang, Y., Liu, Q., … Gu, Z. (2017). A melanin-mediated cancer immunotherapy patch. SCIENCE IMMUNOLOGY, 2(17). https://doi.org/10.1126/sciimmunol.aan5692

Qian, C., Feng, P., Yu, J., Chen, Y., Hu, Q., Sun, W., … Gu, Z. (2017). Anaerobe-Inspired Anticancer Nanovesicles. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(10), 2588–2593. https://doi.org/10.1002/anie.201611783

Wang, C., Sun, W., Ye, Y., Bomba, H. N., & Gu, Z. (2017). [Review of Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs]. THERANOSTICS, 7(14), 3504–3516. https://doi.org/10.7150/thno.19017

Lu, Y., Aimetti, A. A., Langer, R., & Gu, Z. (2017). [Review of Bioresponsive materials]. NATURE REVIEWS MATERIALS, 2(1). https://doi.org/10.1038/natrevmats.2016.75

Yu, J., Zhang, Y., Kahkoska, A. R., & Gu, Z. (2017). [Review of Bioresponsive transcutaneous patches]. CURRENT OPINION IN BIOTECHNOLOGY, 48, 28–32. https://doi.org/10.1016/j.copbio.2017.03.001

Cheng-gen, Q., Chen, Y.-lei, Feng, P.-jian, Xiao, X.-zhong, Dong, M., Yu, J.-cheng, … Gu, Z. (2017). [Review of Conjugated polymer nanomaterials for theranostics]. ACTA PHARMACOLOGICA SINICA, 38(6), 764–781. https://doi.org/10.1038/aps.2017.42

Hu, Q., Bomba, H. N., & Gu, Z. (2017). [Review of Engineering platelet-mimicking drug delivery vehicles]. FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING, 11(4), 624–632. https://doi.org/10.1007/s11705-017-1614-6

Ma, P., Xiao, H., Yu, C., Liu, J., Cheng, Z., Song, H., … Lin, J. (2017). Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species. NANO LETTERS, 17(2), 928–937. https://doi.org/10.1021/acs.nanolett.6b04269

Lu, Y., Lin, Y., Chen, Z., Hu, Q., Liu, Y., Yu, S., … Gu, Z. (2017). Enhanced Endosomal Escape by Light-Fueled Liquid-Metal Transformer. NANO LETTERS, 17(4), 2138–2145. https://doi.org/10.1021/acs.nanolett.6b04346

Bakh, N. A., Cortinas, A. B., Weiss, M. A., Langer, R. S., Anderson, D. G., Gu, Z., … Strano, M. S. (2017). Glucose-responsive insulin by molecular and physical design. NATURE CHEMISTRY, 9(10), 937–943. https://doi.org/10.1038/nchem.2857

Hu, X., Yu, J., Qian, C., Lu, Y., Kahkoska, A. R., Xie, Z., … Gu, Z. (2017). H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery. ACS NANO, 11(1), 613–620. https://doi.org/10.1021/acsnano.6b06892

Yu, J., Qian, C., Zhang, Y., Cui, Z., Zhu, Y., Shen, Q., … Gu, Z. (2017). Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery. NANO LETTERS, 17(2), 733–739. https://doi.org/10.1021/acs.nanolett.6b03848

Wang, C., Sun, W., Ye, Y., Hu, Q., Bomba, H. N., & Gu, Z. (2017). In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy. Nature Biomedical Engineering, 1(2). https://doi.org/10.1038/S41551-016-0011

Wang, C., Sun, W., Wright, G., Wang, A. Z., & Gu, Z. (2017). Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody. Advanced Materials, 29(15). https://doi.org/10.1002/ADMA.201700761

Yu, S., Zhang, D., He, C., Sun, W., Cao, R., Cui, S., … Chen, X. (2017). Injectable Thermosensitive Polypeptide-Based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy. Biomacromolecules, 18(12), 4341–4348. https://doi.org/10.1021/ACS.BIOMAC.7B01374

Qian, C., Feng, P., Yu, J., Chen, Y., Hu, Q., Sun, W., … Gu, Z. (2017). Inside Cover: Anaerobe-Inspired Anticancer Nanovesicles (Angew. Chem. Int. Ed. 10/2017). Angewandte Chemie International Edition, 56(10), 2516–2516. https://doi.org/10.1002/ANIE.201701131

Yu, J., Zhang, Y., Sun, W., Kahkoska, A. R., Wang, J., Buse, J. B., & Gu, Z. (2017). Insulin-Responsive Glucagon Delivery for Prevention of Hypoglycemia. Small, 13(19), 1603028. https://doi.org/10.1002/SMLL.201603028

Yu, J. C., Zhang, Y. Q., Sun, W. J., Kahkoska, A. R., Wang, J. Q., Buse, J. B., & Gu, Z. (2017). Insulin-responsive glucagon delivery for prevention of hypoglycemia. Small (Weinheim An Der Bergstrasse, Germany), 13(19). https://doi.org/10.1002/smll.201770108

Zhang, X., Liang, X., Gu, J., Chang, D., Zhang, J., Chen, Z., … Gu, Z. (2017). Investigation and intervention of autophagy to guide cancer treatment with nanogels. NANOSCALE, 9(1), 150–163. https://doi.org/10.1039/c6nr07866d

Lu, Y., & Gu, Z. (2017, November). KIDNEY PHYSIOLOGYA size bandpass filter. NATURE NANOTECHNOLOGY, Vol. 12, pp. 1023–1025. https://doi.org/10.1038/nnano.2017.200

Gu, C., Nguyen, H.-N., Ganini, D., Chen, Z., Jessen, H. J., Gu, Z., … Shears, S. B. (2017). KO of 5-InsP(7) kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(45), 11968–11973. https://doi.org/10.1073/pnas.1702370114

Sun, W., Hu, Q., Ji, W., Wright, G., & Gu, Z. (2017). [Review of LEVERAGING PHYSIOLOGY FOR PRECISION DRUG DELIVERY]. PHYSIOLOGICAL REVIEWS, 97(1), 189–225. https://doi.org/10.1152/physrev.00015.2016

Wang, J., Zhang, Y., Archibong, E., Ligler, F. S., & Gu, Z. (2017). Leveraging H2O2Levels for Biomedical Applications. Advanced Biosystems, 1(9), 1700084. https://doi.org/10.1002/ADBI.201700084

Wang, C., Ye, Y., & Gu, Z. (2017). Local delivery of checkpoints antibodies. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 13(1), 245–248. https://doi.org/10.1080/21645515.2016.1223000

Zhang, Y., Liu, Q., Yu, J., Yu, S., Wang, J., Qiang, L., & Gu, Z. (2017). Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment. ACS NANO, 11(9), 9223–9230. https://doi.org/10.1021/acsnano.7b04348

Zhang, Y., Yu, J., Kahkoska, A. R., & Gu, Z. (2017). [Review of Photoacoustic Drug Delivery]. SENSORS, 17(6). https://doi.org/10.3390/s17061400

Yan, J., Yu, J., Wang, C., & Gu, Z. (2017). Red Blood Cells for Drug Delivery. Small Methods, 1(12), 1700270. https://doi.org/10.1002/SMTD.201700270

Wang, C., Ye, Y., Sun, W., Yu, J., Wang, J., Lawrence, D. S., … Gu, Z. (2017). Red Blood Cells for Glucose-Responsive Insulin Delivery. ADVANCED MATERIALS, 29(18). https://doi.org/10.1002/adma.201606617

Hu, Q., Sun, W., Qian, C., Bomba, H. N., Xin, H., & Gu, Z. (2017). Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy. ADVANCED MATERIALS, 29(13). https://doi.org/10.1002/adma.201605803

Zhang, Y. Q., Wang, M. Z., Yu, J. C., & Gu, Z. (2017). Smart materials and systems as artificial pancreas for diabetes treatment. Smart Materials for Tissue Engineering: Applications, 25, 358–381.

Hu, X., Zhang, Y., Xie, Z., Jing, X., Bellotti, A., & Gu, Z. (2017). Stimuli-Responsive Polymersomes for Biomedical Applications. BIOMACROMOLECULES, 18(3), 649–673. https://doi.org/10.1021/acs.biomac.6b01704

Chen, Z., Wang, J., Sun, W., Archibong, E., Kahkoska, A. R., Zhang, X., … Gu, Z. (2017). Synthetic beta cells for fusion-mediated dynamic insulin secretion. Nature Chemical Biology, 14(1), 86–93. https://doi.org/10.1038/nchembio.2511

Wang, C., Ye, Y., Hu, Q., Bellotti, A., & Gu, Z. (2017). Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook. ADVANCED MATERIALS, 29(29). https://doi.org/10.1002/adma.201606036

Sun, W. J., & Gu, Z. (2017). [Review of Tailoring non-viral delivery vehicles for transporting genome-editing tools]. Science China-Materials, 60(6), 511–515. https://doi.org/10.1007/s40843-016-5154-4

Zhang, Y. Q., Yu, J. C., Wang, J. Q., Hanne, N. J., Cui, Z., Qian, C. G., … Gu, Z. (2017). Thrombin-responsive transcutaneous patch for auto-anticoagulant regulation. Advanced Materials, 29(4). https://doi.org/10.1002/adma.201770028

Di, J., Yu, J., Wang, Q., Yao, S., Suo, D., Ye, Y., … Gu, Z. (2017). Ultrasound-triggered noninvasive regulation of blood glucose levels using microgels integrated with insulin nanocapsules. Nano Research, 10(4), 1393–1402. https://doi.org/10.1007/s12274-017-1500-z

Sun, W., & Gu, Z. (2016, March 3). ATP-Responsive Drug Delivery Systems. EXPERT OPINION ON DRUG DELIVERY, Vol. 13, pp. 311–314. https://doi.org/10.1517/17425247.2016.1140147

Qian, C., Chen, Y., Zhu, S., Yu, J., Zhang, L., Feng, P., … Gu, Z. (2016). ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging. THERANOSTICS, 6(7), 1053–1064. https://doi.org/10.7150/thno.14843

Qian, C., Yu, J., Chen, Y., Hu, Q., Xiao, X., Sun, W., … Gu, Z. (2016). Anticancer Therapy: Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy (Adv. Mater. 17/2016). Advanced Materials, 28(17), 3226–3226. https://doi.org/10.1002/ADMA.201670115

Hu, Q. Y., & Gu, Z. (2016). Cell membrane-mediated anticancer drug delivery. Nanotechnology: delivering on the promise, vol 2, 1224, 197–211.

Ye, Y., Yu, J., Wang, C., Nguyen, N.-Y., Walker, G. M., Buse, J. B., & Gu, Z. (2016). Drug Delivery: Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery (Adv. Mater. 16/2016). Advanced Materials, 28(16), 3223–3223. https://doi.org/10.1002/ADMA.201670112

Zhao, Y., Jiang, Y., Lv, W., Wang, Z., Lv, L., Wang, B., … Gu, Z. (2016). Dual targeted nanocarrier for brain ischemic stroke treatment. JOURNAL OF CONTROLLED RELEASE, 233, 64–71. https://doi.org/10.1016/j.jconrel.2016.04.038

Zhang, Y., Yu, J., Zhu, Y., & Gu, Z. (2016). Elastic drug delivery: could treatments be triggered by patient movement? NANOMEDICINE, Vol. 11, pp. 323–325. https://doi.org/10.2217/nnm.15.197

Hu, Q., Qian, C., Sun, W., Wang, J., Chen, Z., Bomba, H. N., … Gu, Z. (2016). Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus. ADVANCED MATERIALS, 28(43), 9573-+. https://doi.org/10.1002/adma.201603463

Lv, L., Jiang, Y., Liu, X., Wang, B., Lv, W., Zhao, Y., … Gu, Z. (2016). Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles. MOLECULAR PHARMACEUTICS, 13(10), 3506–3517. https://doi.org/10.1021/acs.molpharmaceut.6b00523

Wang, C., Ye, Y., Hochu, G. M., Sadeghifar, H., & Gu, Z. (2016). Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody. NANO LETTERS, 16(4), 2334–2340. https://doi.org/10.1021/acs.nanolett.5b05030

Yu, J., Zhang, Y., Hu, X., Wright, G., & Gu, Z. (2016). Hypoxia-Sensitive Materials for Biomedical Applications. ANNALS OF BIOMEDICAL ENGINEERING, 44(6), 1931–1945. https://doi.org/10.1007/s10439-016-1578-6

Wang, C., Sun, W., Wright, G., Wang, A. Z., & Gu, Z. (2016). Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody. ADVANCED MATERIALS, 28(40), 8912–8920. https://doi.org/10.1002/adma.201506312

Yu, J., Zhang, Y., Sun, W., Wang, C., Ranson, D., Ye, Y., … Gu, Z. (2016). Internalized compartments encapsulated nanogels for targeted drug delivery. NANOSCALE, 8(17), 9178–9184. https://doi.org/10.1039/c5nr08895j

Gu, Z. (2016). Introduction to special issue on “Responsive Materials and Systems: Toward Smart and Precision Medications.” Bioengineering & Translational Medicine, 1(3), 235–236. https://doi.org/10.1002/BTM2.10045

Qian, C., Yu, J., Chen, Y., Hu, Q., Xiao, X., Sun, W., … Gu, Z. (2016). Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy. ADVANCED MATERIALS, 28(17), 3313–3320. https://doi.org/10.1002/adma.201505869

Zhang, Y., Yu, J., Bomba, H. N., Zhu, Y., & Gu, Z. (2016). [Review of Mechanical Force-Triggered Drug Delivery]. CHEMICAL REVIEWS, 116(19), 12536–12563. https://doi.org/10.1021/acs.chemrev.6b00369

Ye, Y., Yu, J., Wang, C., Nguyen, N.-Y., Walker, G. M., Buse, J. B., & Gu, Z. (2016). Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery. Advanced Materials, 28(16), 3115–3121. https://doi.org/10.1002/adma.201506025

Shi, D., Xu, X., Ye, Y., Song, K., Cheng, Y., Di, J., … Gu, Z. (2016). Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration. ACS NANO, 10(1), 1292–1299. https://doi.org/10.1021/acsnano.5b06663

Hu, Q., Sun, W., Wang, C., & Gu, Z. (2016). [Review of Recent advances of cocktail chemotherapy by combination drug delivery systems]. ADVANCED DRUG DELIVERY REVIEWS, 98, 19–34. https://doi.org/10.1016/j.addr.2015.10.022

Yu, J., Zhang, Y., Bomba, H., & Gu, Z. (2016). Stimuli-responsive delivery of therapeutics for diabetes treatment. Bioengineering & Translational Medicine, 1(3), 323–337. https://doi.org/10.1002/BTM2.10036

Ye, Y., Wang, J., Hu, Q., Hochu, G. M., Xin, H., Wang, C., & Gu, Z. (2016). Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors. ACS NANO, 10(9), 8956–8963. https://doi.org/10.1021/acsnano.6b04989

Zhang, Y., Yu, J., Wang, J., Hanne, N. J., Cui, Z., Qian, C., … Gu, Z. (2016). Thrombin-Responsive Transcutaneous Patch for Auto-Anticoagulant Regulation. Advanced Materials, 29(4), 1604043. https://doi.org/10.1002/ADMA.201604043

Sun, W., Ji, W., Hu, Q., Yu, J., Wang, C., Qian, C., … Gu, Z. (2016). Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine. BIOMATERIALS, 96, 1–10. https://doi.org/10.1016/j.biomaterials.2016.04.011

Hu, Q., Sun, W., Lu, Y., Bomba, H. N., Ye, Y., Jiang, T., … Gu, Z. (2016). Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots. NANO LETTERS, 16(2), 1118–1126. https://doi.org/10.1021/acs.nanolett.5b04343

Mo, R., & Gu, Z. (2016). Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery. MATERIALS TODAY, 19(5), 274–283. https://doi.org/10.1016/j.mattod.2015.11.025

Ye, Y., Yu, J., & Gu, Z. (2016). Versatile Protein Nanogels Prepared by In Situ Polymerization. MACROMOLECULAR CHEMISTRY AND PHYSICS, 217(3), 333–343. https://doi.org/10.1002/macp.201500296

Pacardo, D. B., Neupane, B., Rikard, S. M., Lu, Y., Mo, R., Mishra, S. R., … Gu, Z. (2015). A dual wavelength-activatable gold nanorod complex for synergistic cancer treatment. NANOSCALE, 7(28), 12096–12103. https://doi.org/10.1039/c5nr01568e

Pacardo, D. B., Neupane, B., Wang, G., Gu, Z., Walker, G. M., & Ligler, F. S. (2015). A temperature microsensor for measuring laser-induced heating in gold nanorods. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(3), 719–725. https://doi.org/10.1007/s00216-014-8222-9

Mo, R., Jiang, T., Sun, W., & Gu, Z. (2015). ATP-responsive DNA-graphene hybrid nanoaggregates for anticancer drug delivery. BIOMATERIALS, 50, 67–74. https://doi.org/10.1016/j.biomaterials.2015.01.053

Mitragotri, S., Anderson, D. G., Chen, X., Chow, E. K., Ho, D., Kabanov, A. V., … Xu, C. (2015). Accelerating the Translation of Nanomaterials in Biomedicine. ACS NANO, 9(7), 6644–6654. https://doi.org/10.1021/acsnano.5b03569

Hu, Q., Sun, W., Qian, C., Wang, C., Bomba, H. N., & Gu, Z. (2015). Anticancer Platelet-Mimicking Nanovehicles. ADVANCED MATERIALS, 27(44), 7043-+. https://doi.org/10.1002/adma.201503323

Ji, W., Sun, W., Feng, J., Song, T., Zhang, D., Ouyang, P., … Xie, J. (2015). Characterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesis. SCIENTIFIC REPORTS, 5. https://doi.org/10.1038/srep09341

Xiao-Hui, L., Ji-Cheng, Y., Nai-Yan, L., Wei-Dong, Z., Yu-Yan, W., & Zhen, G. (2015). Confinement-induced nanocrystal alignment of conjugated polymer by the soft-stamped nanoimprint lithography. CHINESE PHYSICS B, 24(10). https://doi.org/10.1088/1674-1056/24/10/104215

Sun, W., Ji, W., Hall, J. M., Hu, Q., Wang, C., Beisel, C. L., & Gu, Z. (2015). Cover Picture: Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing (Angew. Chem. Int. Ed. 41/2015). Angewandte Chemie International Edition, 54(41), 11877–11877. https://doi.org/10.1002/ANIE.201508399

Jiang, T., Sun, W., Zhu, Q., Burns, N. A., Khan, S. A., Mo, R., & Gu, Z. (2015). Drug Delivery: Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene (Adv. Mater. 6/2015). Advanced Materials, 27(6), 958–958. https://doi.org/10.1002/ADMA.201570035

Sun, W., & Gu, Z. (2015). [Review of Engineering DNA scaffolds for delivery of anticancer therapeutics]. BIOMATERIALS SCIENCE, 3(7), 1018–1024. https://doi.org/10.1039/c4bm00459k

Di, J., Yu, J., Ye, Y., Ranson, D., Jindal, A., & Gu, Z. (2015). Engineering Synthetic Insulin-Secreting Cells Using Hyaluronic Acid Microgels Integrated with Glucose-Responsive Nanoparticles. CELLULAR AND MOLECULAR BIOENGINEERING, 8(3), 445–454. https://doi.org/10.1007/s12195-015-0390-y

Zhang, Y. Q., Yu, J. C., Shen, Q. D., & Gu, Z. (2015). [Review of Glucose-responsive synthetic closed-loop insulin delivery systems]. Progress in Chemistry, 27(1), 11–26.

Chen, Y., Nan, J., Lu, Y., Wang, C., Chu, F., & Gu, Z. (2015). Hybrid Fe3O4-Poly(acrylic acid) Nanogels for Theranostic Cancer Treatment. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 11(5), 771–779. https://doi.org/10.1166/jbn.2015.2001

Yu, J., Zhang, Y., Ye, Y., DiSanto, R., Sun, W., Ranson, D., … Gu, Z. (2015). Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265. https://doi.org/10.1073/pnas.1505405112

Hu, Q., Sun, W., Qian, C., Wang, C., Bomba, H. N., & Gu, Z. (2015). Nanomedicine: Anticancer Platelet-Mimicking Nanovehicles (Adv. Mater. 44/2015). Advanced Materials, 27(44), 7014–7014. https://doi.org/10.1002/ADMA.201570298

Yan, B., Li, B., Kunecke, F., Gu, Z., & Guo, L. (2015). Polypyrrole-Based Implantable Electroactive Pump for Controlled Drug Microinjection. ACS APPLIED MATERIALS & INTERFACES, 7(27), 14563–14568. https://doi.org/10.1021/acsami.5b04551

Pacardo, D. B., Ligler, F. S., & Gu, Z. (2015). [Review of Programmable nanomedicine: synergistic and sequential drug delivery systems]. NANOSCALE, 7(8), 3381–3391. https://doi.org/10.1039/c4nr07677j

DiSanto, R. M., Subramanian, V., & Gu, Z. (2015). [Review of Recent advances in nanotechnology for diabetes treatment]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 7(4), 548–564. https://doi.org/10.1002/wnan.1329

Sun, W., Ji, W., Hall, J. M., Hu, Q., Wang, C., Beisel, C. L., & Gu, Z. (2015). Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing. Angewandte Chemie International Edition, 54(41), 12029–12033. https://doi.org/10.1002/anie.201506030

Di, J., Kim, J., Hu, Q., Jiang, X., & Gu, Z. (2015, December 28). Spatiotemporal drug delivery using laser-generated-focused ultrasound system. JOURNAL OF CONTROLLED RELEASE, Vol. 220, pp. 592–599. https://doi.org/10.1016/j.jconrel.2015.08.033

Di, J., Yao, S., Ye, Y., Cui, Z., Yu, J., Ghosh, T. K., … Gu, Z. (2015). Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots. ACS NANO, 9(9), 9407–9415. https://doi.org/10.1021/acsnano.5b03975

Lu, Y., Hu, Q., Lin, Y., Pacardo, D. B., Wang, C., Sun, W., … Gu, Z. (2015). Transformable liquid-metal nanomedicine. NATURE COMMUNICATIONS, 6(1). https://doi.org/10.1038/ncomms10066

Mo, R., Jiang, T., DiSanto, R., Tai, W., & Gu, Z. (2014). ATP-triggered anticancer drug delivery. NATURE COMMUNICATIONS, 5. https://doi.org/10.1038/ncomms4364

Sun, W., Lu, Y., & Gu, Z. (2014). Advances in Anticancer Protein Delivery using Micro-/Nanoparticles. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 31(12), 1204–1222. https://doi.org/10.1002/ppsc.201400140

Tai, W., Mo, R., Di, J., Subramanian, V., Gu, X., Buse, J. B., & Gu, Z. (2014). Bio-lnspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin. BIOMACROMOLECULES, 15(10), 3495–3502. https://doi.org/10.1021/bm500364a

Zhao, M., Liu, Y., Hsieh, R. S., Wang, N., Tai, W., Joo, K.-I., … Tang, Y. (2014). Clickable Protein Nanocapsules for Targeted Delivery of Recombinant p53 Protein. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(43), 15319–15325. https://doi.org/10.1021/ja508083g

Sun, W., Jiang, T., Lu, Y., Reiff, M., Mo, R., & Gu, Z. (2014). Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(42), 14722–14725. https://doi.org/10.1021/ja5088024

Jiang, T., Mo, R., Bellotti, A., Zhou, J., & Gu, Z. (2014). Drug Delivery: Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy (Adv. Funct. Mater. 16/2014). Advanced Functional Materials, 24(16), 2258–2258. https://doi.org/10.1002/ADFM.201470099

Di, J., Price, J., Gu, X., Jiang, X., Jing, Y., & Gu, Z. (2014). Drug Delivery: Ultrasound-Triggered Regulation of Blood Glucose Levels Using Injectable Nano-Network (Adv. Healthcare Mater. 6/2014). Advanced Healthcare Materials, 3(6), 789–789. https://doi.org/10.1002/ADHM.201470027

Mo, R., Jiang, T., Di, J., Tai, W., & Gu, Z. (2014). [Review of Emerging micro-and nanotechnology based synthetic approaches for insulin delivery]. CHEMICAL SOCIETY REVIEWS, 43(10), 3595–3629. https://doi.org/10.1039/c3cs60436e

Mo, R., Jiang, T., & Gu, Z. (2014). Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53(23), 5815–5820. https://doi.org/10.1002/anie.201400268

Hu, Q., Katti, P. S., & Gu, Z. (2014). Enzyme-responsive nanomaterials for controlled drug delivery. NANOSCALE, 6(21), 12273–12286. https://doi.org/10.1039/c4nr04249b

Tai, W., Mo, R., Lu, Y., Jiang, T., & Gu, Z. (2014). Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs. BIOMATERIALS, 35(25), 7194–7203. https://doi.org/10.1016/j.biomaterials.2014.05.004

Jiang, T., Sun, W., Zhu, Q., Burns, N. A., Khan, S. A., Mo, R., & Gu, Z. (2014). Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene. Advanced Materials, 27(6), 1021–1028. https://doi.org/10.1002/ADMA.201404498

Dong, Y., Eltoukhy, A. A., Alabi, C. A., Khan, O. F., Veiseh, O., Dorkin, J. R., … Anderson, D. G. (2014). Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo. Advanced Healthcare Materials, 3(9), 1392–1397. https://doi.org/10.1002/ADHM.201400054

Jiang, T., Mo, R., Bellotti, A., Zhou, J., & Gu, Z. (2014). Molecule Drugs for Enhanced Therapeutic Efficacy. ADVANCED FUNCTIONAL MATERIALS, 24(16), 2295–2304. https://doi.org/10.1002/adfm.201303222

Mo, R., Jiang, T., & Gu, Z. (2014, June). Recent progress in multidrug delivery to cancer cells by liposomes. NANOMEDICINE, Vol. 9, pp. 1117–1120. https://doi.org/10.2217/nnm.14.62

Lu, Y., Mo, R., Tai, W., Sun, W., Pacardo, D. B., Qian, C., … Gu, Z. (2014). Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery. CHEMICAL COMMUNICATIONS, 50(95), 15105–15108. https://doi.org/10.1039/c4cc07004f

Lu, Y., Sun, W., & Gu, Z. (2014). [Review of Stimuli-responsive nanomaterials for therapeutic protein delivery]. JOURNAL OF CONTROLLED RELEASE, 194, 1–19. https://doi.org/10.1016/j.jconrel.2014.08.015

Yu, J.-C., Chen, Y.-L., Zhang, Y.-Q., Yao, X.-K., Cheng-Gen, Q., Huang, J., … Gu, Z. (2014). pH-Responsive and near-infrared-emissive polymer nanoparticles for simultaneous delivery, release, and fluorescence tracking of doxorubicin in vivo. CHEMICAL COMMUNICATIONS, 50(36), 4699–4702. https://doi.org/10.1039/c3cc49870k

Zhao, M., Hu, B., Gu, Z., Joo, K.-I., Wang, P., & Tang, Y. (2013). Degradable polymeric nanocapsule for efficient intracellular delivery of a high molecular weight tumor-selective protein complex. Nano Today, 8(1), 11–20. https://doi.org/10.1016/j.nantod.2012.12.003

Zhang, Y., Pelet, J. M., Heller, D. A., Dong, Y., Chen, D., Gu, Z., … Anderson, D. G. (2013). Drug Delivery: Lipid-Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery (Adv. Mater. 33/2013). Advanced Materials, 25(33), 4680–4680. https://doi.org/10.1002/ADMA.201370207

Dang, T. T., Thai, A. V., Cohen, J., Slosberg, J. E., Siniakowicz, K., Doloff, J. C., … Anderson, D. G. (2013). Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug. Biomaterials, 34(23), 5792–5801. https://doi.org/10.1016/J.BIOMATERIALS.2013.04.016

Gu, Z., Dang, T. T., Ma, M., Tang, B. C., Cheng, H., Jiang, S., … Anderson, D. G. (2013). Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery. ACS NANO, 7(8), 6758–6766. https://doi.org/10.1021/nn401617u

Wang, Q., Gu, Z., Jamal, S., Detamore, M. S., & Berkland, C. (2013). Hybrid Hydroxyapatite Nanoparticle Colloidal Gels are Injectable Fillers for Bone Tissue Engineering. TISSUE ENGINEERING PART A, 19(23-24), 2586–2593. https://doi.org/10.1089/ten.tea.2013.0075

Gu, Z., Aimetti, A. A., Wang, Q., Dang, T. T., Zhang, Y., Veiseh, O., … Anderson, D. G. (2013). Injectable Nano-Network for Glucose-Mediated Insulin Delivery. ACS NANO, 7(5), 4194–4201. https://doi.org/10.1021/nn400630x

Zhang, Y., Pelet, J. M., Heller, D. A., Dong, Y., Chen, D., Gu, Z., … Anderson, D. G. (2013). Lipid-Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery. Advanced Materials, 25(33), 4641–4645. https://doi.org/10.1002/ADMA.201301917

Di, J., Price, J., Gu, X., Jiang, X., Jing, Y., & Gu, Z. (2013). Ultrasound-Triggered Regulation of Blood Glucose Levels Using Injectable Nano-Network. Advanced Healthcare Materials, 3(6), 811–816. https://doi.org/10.1002/adhm.201300490

Gu, Z., Zhao, M., Sheng, Y., Bentolila, L. A., & Tang, Y. (2011). Detection of Mercury Ion by Infrared Fluorescent Protein and Its Hydrogel-Based Paper Assay. Analytical Chemistry, 83(6), 2324–2329. https://doi.org/10.1021/ac103236g

Biswas, A., Joo, K.-I., Liu, J., Zhao, M., Fan, G., Wang, P., … Tang, Y. (2011). Endoprotease-Mediated Intracellular Protein Delivery Using Nanocapsules. ACS Nano, 5(2), 1385–1394. https://doi.org/10.1021/nn1031005

Joo, K.-I., Fang, Y., Liu, Y., Xiao, L., Gu, Z., Tai, A., … Wang, P. (2011). Enhanced Real-Time Monitoring of Adeno-Associated Virus Trafficking by Virus–Quantum Dot Conjugates. ACS Nano, 5(5), 3523–3535. https://doi.org/10.1021/nn102651p

Zhao, M., Biswas, A., Hu, B., Joo, K.-I., Wang, P., Gu, Z., & Tang, Y. (2011). Redox-responsive nanocapsules for intracellular protein delivery. Biomaterials, 32(22), 5223–5230. https://doi.org/10.1016/j.biomaterials.2011.03.060

Gu, Z., Biswas, A., Zhao, M., & Tang, Y. (2011). Tailoring nanocarriers for intracellular protein delivery. Chemical Society Reviews, 40(7), 3638. https://doi.org/10.1039/c0cs00227e

Sun, B., Sun, M.-J., Gu, Z., Shen, Q.-D., Jiang, S.-J., Xu, Y., & Wang, Y. (2010). Conjugated Polymer Fluorescence Probe for Intracellular Imaging of Magnetic Nanoparticles. Macromolecules, 43(24), 10348–10354. https://doi.org/10.1021/ma101680g

Gu, Z., & Tang, Y. (2010). Enzyme-assisted photolithography for spatial functionalization of hydrogels. Lab on a Chip, 10(15), 1946. https://doi.org/10.1039/c001335h

Gu, Z., Chen, X.-Y., Shen, Q.-D., Ge, H.-X., & Xu, H.-H. (2010). Hybrid nanocomposites of semiconductor nanoparticles and conjugated polyelectrolytes and their application as fluorescence biosensors. Polymer, 51(4), 902–907. https://doi.org/10.1016/j.polymer.2009.12.035

Gu, Z., Biswas, A., Joo, K.-I., Hu, B., Wang, P., & Tang, Y. (2010). Probing protease activity by single-fluorescent-protein nanocapsules. Chemical Communications, 46(35), 6467. https://doi.org/10.1039/c0cc01439g

Yan, M., Du, J., Gu, Z., Liang, M., Hu, Y., Zhang, W., … Lu, Y. (2009). A novel intracellular protein delivery platform based on single-protein nanocapsules. Nature Nanotechnology, 5(1), 48–53. https://doi.org/10.1038/nnano.2009.341

Gu, Z., Huang, S., & Chen, Y. (2009). Biomolecular Nanopatterning by Magnetic Electric Lithography. Angewandte Chemie International Edition, 48(5), 952–955. https://doi.org/10.1002/anie.200803456

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