2022 journal article

Ligand-induced transmembrane conformational coupling in monomeric EGFR

Nature Communications.

By: S. Srinivasan*, R. Regmi *, X. Lin* , C. Dreyer*, X. Chen *, S. Quinn *, W. He *, M. Coleman * ...

MeSH headings : Cell Membrane / metabolism; ErbB Receptors / metabolism; Ligands; Protein Binding; Protein Conformation
TL;DR: It is shown that transmembrane conformational coupling is the first step in EGFR signaling, providing evidence for the existence of trans Membrane intramolecular conformational changes in a single pass membrane protein. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: April 5, 2023

Abstract