2023 article

Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing

Shih, Y.-R. V., Kingsley, D., Newman, H., Hoque, J., Gupta, A., Lascelles, B. D. X., & Varghese, S. (2023, November 8). ADVANCED SCIENCE.

By: Y. Shih *, D. Kingsley *, H. Newman *, J. Hoque*, A. Gupta n , B. Lascelles n, S. Varghese *

author keywords: adenosine; adenosine receptors; biomaterials; drug delivery; fracture healing; fracture pain; phenylboronic acids
TL;DR: The results demonstrate that local delivery of adenosine inhibited the nociceptive activity of peripheral neurons through activation of adenosine A1 receptor (ADORA1) and mitigated pain as demonstrated by weight bearing and open field movement tests. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: December 4, 2023

Abstract