Estrogen receptor alpha, G-protein coupled estrogen receptor 1, and aromatase: Developmental, sex, and region-specific differences across the rat caudate-putamen, nucleus accumbens core and shell
JOURNAL OF COMPARATIVE NEUROLOGY, 529(4), 786–801.
author keywords: aromatase; estrogen receptor; rat; RRID AB_1141090; RRID AB_310305; RRID AB_566942; sex differences; striatum
MeSH headings : Animals; Caudate Nucleus / chemistry; Caudate Nucleus / growth & development; Caudate Nucleus / metabolism; Estrogen Receptor alpha / analysis; Estrogen Receptor alpha / biosynthesis; Female; Male; Nucleus Accumbens / chemistry; Nucleus Accumbens / growth & development; Nucleus Accumbens / metabolism; Putamen / chemistry; Putamen / growth & development; Putamen / metabolism; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled / analysis; Receptors, G-Protein-Coupled / biosynthesis; Sex Characteristics
TL;DR:
The hypothesis that ERα, GPER1, and aromatase exhibits sex, region, and age‐specific differences, including nuclear expression is tested, indicating that developmental period exerts critical sex‐specific influences on striatal cellular estrogenic mechanisms.
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