Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis
Leukemia , 28 (5), 1138–1142.
By: S. Peters* , R. Hlady* , J. Opavska* , D. Klinkebiel * , S. Pirruccello* , G. Talmon * , J. Sharp* , L. Wu * ...and 4 other authors, including 1 NC State author , R. Jaenisch * , M. Simpson * , A. Karpf * & R. Opavsky*
MeSH headings : Animals; DNA (Cytosine-5-)-Methyltransferases / metabolism; DNA Methyltransferase 3A; Genes, Tumor Suppressor; Lymphoma / enzymology; Lymphoma / pathology; Lymphopoiesis; Mice
TL;DR:
Tumor suppressor functions of DnMT3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis are inhibited and cell death is prevented in mice treated with F508(B) deletion.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
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Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis