MeSH headings : Adaptor Proteins, Signal Transducing; Animals; Cell Movement / physiology; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Female; Focal Adhesion Kinase 1 / metabolism; Mammary Neoplasms, Experimental / genetics; Mammary Neoplasms, Experimental / metabolism; Mammary Neoplasms, Experimental / pathology; Mammary Tumor Virus, Mouse / genetics; Mice; Mice, Inbred C57BL; Proteins / genetics; Proteins / metabolism; Signal Transduction

TL;DR: It is shown that the Nedd9-null genetic background significantly limits mammary tumor initiation in the MMTV-polyoma virus middle T genetic model and suggests that NEDD9 expression may provide a biomarker for tumor aggressiveness. (via Semantic Scholar)