Telomere dysfunction in Tert knockout mice delays Braf<SUP>V600E</SUP>-induced melanoma development
Zhang, J., Zhang, F., Porter, K. I., Dakup, P. P., Wang, S., Robertson, G. P., … Zhu, J. (2023, September 20). INTERNATIONAL JOURNAL OF CANCER.
author keywords: BRAF; melanoma; mouse model; telomerase; telomere dysfunction
TL;DR:
It is suggested that telomere dysfunction hampers melanomagenesis, and targeting telomeres crisis‐mediated genomic instability may hold promise for the prevention and treatment of melanoma.
(via
Semantic Scholar)
UN Sustainable Development Goal Categories