2022 journal article

Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chlamydia


By: C. Liu*, K. Hufnagel*, . Catherine M. O'Connell*, N. Goonetilleke*, N. Mokashi*, T. Waterboer*, T. Tollison n, X. Peng n ...

author keywords: Chlamydia; genital tract; antibody; serology; endometrium; immunoproteome
MeSH headings : Antibodies, Bacterial; Chlamydia Infections; Chlamydia trachomatis; Female; Humans; Immunoglobulin G; Reinfection
TL;DR: Protein-specific CT antibodies are not sufficient to protect against ascending or incident infection but broad recognition of CT proteins by IgG correlates with cervical CT gene transcript abundance, suggesting CT protein abundance correlates with immunogenicity and signifies their potential as vaccine candidates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: March 21, 2022