Hepatic endopolyploidy as a cellular consequence of age‐specific selection for rate of development in mice
Funk‐Keenan, J., Haire, F., Woolard, S., & Atchley, W. R. (2008, February 4). Journal of Experimental Zoology Part B Molecular and Developmental Evolution.
By:
J. Funk‐Keenan n, F. Haire n, S. Woolard n & W. Atchley n
MeSH headings : Aging / genetics; Aging / pathology; Animals; Female; Flow Cytometry; Growth; Liver / metabolism; Liver / pathology; Male; Mice; Mice, Inbred ICR; Polyploidy
topics (OpenAlex): Chromosomal and Genetic Variations; Evolution and Genetic Dynamics; Genetic Mapping and Diversity in Plants and Animals
TL;DR:
This work searches for endopolyploidy in the liver in response to age-specific restricted index selection for the rate of development in mice, finding lines selected for divergence in early growth and late growth are divergent in frequency of polyploid cells.
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