Laura N. Healy

Works (3)

Updated: July 5th, 2023 16:02

1999 article

Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice

Christensen, J. G. (1999, August 1). Carcinogenesis.

By: J. Christensen n

MeSH headings : Adenoma / chemically induced; Adenoma / metabolism; Adenoma / pathology; Animals; Apoptosis; Carcinogens; Carcinoma / chemically induced; Carcinoma / metabolism; Carcinoma / pathology; Carrier Proteins / metabolism; Chlordan; DNA-Binding Proteins; Liver Neoplasms, Experimental / chemically induced; Liver Neoplasms, Experimental / metabolism; Liver Neoplasms, Experimental / pathology; Male; Mice; Neoplasm Proteins / metabolism; Phenobarbital; Phenotype; Polychlorinated Dibenzodioxins; Proto-Oncogene Proteins / metabolism; Proto-Oncogene Proteins c-bcl-2 / metabolism; Pyrimidines; Transcription Factors; bcl-2-Associated X Protein; bcl-X Protein
topics (OpenAlex): Cell death mechanisms and regulation; Drug Transport and Resistance Mechanisms; Drug-Induced Hepatotoxicity and Protection
TL;DR: The results suggest that regulation of apoptotic proteins is altered during non-genotoxic carcinogenesis in mouse liver and there were both chemical- and lesion-specific aspects of expression of apoptosis proteins during hepatocarcinogenesis in mice. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 article

Atypical Limbal Melanoma in a Cat

Betton, A., Healy, L. N., English, R. V., & Bunch, S. E. (1999, January 1). Journal of Veterinary Internal Medicine.

By: A. Betton n, L. Healy n, R. English n & S. Bunch n

topics (OpenAlex): Veterinary Oncology Research; Infectious Diseases and Mycology; Virus-based gene therapy research
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UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 article

Expression and distribution of cytochrome P450 2E1 in B6C3F1 mouse liver and testes

Healy, L. N., Pluta, L. J., & Recio, L. (1999, July 1). Chemico-Biological Interactions.

By: L. Healy n, L. Pluta * & L. Recio*

author keywords: cytochrome P450 2E1; testes; liver; B6C3F1 mouse; immunohistochemistry
MeSH headings : Animals; Blotting, Western; Cytochrome P-450 CYP2E1 / genetics; Cytochrome P-450 CYP2E1 / metabolism; DNA / analysis; DNA Primers / chemistry; Electrophoresis, Agar Gel; Immunoenzyme Techniques; Liver / chemistry; Liver / enzymology; Male; Mice; Mice, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Testis / chemistry; Testis / enzymology; Tissue Distribution
topics (OpenAlex): Pharmacogenetics and Drug Metabolism; Carcinogens and Genotoxicity Assessment; Metabolism and Genetic Disorders
TL;DR: Results suggest that in situ bioactivation of BD in testes by CYP2E1 may contribute to BD-induced germ cell genotoxicity. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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