2001 journal article

Efficient assessment of modified nucleoside stability under conditions of automated oligonucleotide synthesis: Characterization of the oxidation and oxidative desulfurization of 2-thiouridine


By: E. Sochacka*

MeSH headings : Acetonitriles / chemistry; Carbon Tetrachloride / chemistry; Chromatography, High Pressure Liquid; Hydrogen Peroxide / chemistry; Models, Chemical; Nucleic Acid Denaturation; Oligonucleotides / chemical synthesis; Oligonucleotides / chemistry; Oxygen / metabolism; Sulfur / chemistry; Thiouridine / analogs & derivatives; Thiouridine / chemistry; Time Factors
TL;DR: A scheme in which the modified nucleoside, directly attached to a solid support, is exposed to the cyclic chemistry of the instrument, and stability of 2-thiouridine against different oxidizers was investigated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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