Arthi Jayaraman

Works (6)

Updated: July 5th, 2023 15:57

2007 journal article

Computer simulation study of probe-target hybridization in model DNA microarrays: Effect of probe surface density and target concentration

JOURNAL OF CHEMICAL PHYSICS, 127(14).

By: A. Jayaraman n, C. Hall n  & J. Genzer n 

MeSH headings : Binding Sites; Biosensing Techniques / methods; Computer Simulation; DNA Probes; Monte Carlo Method; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis / methods; Probability; Sensitivity and Specificity; Thermodynamics
TL;DR: The results suggest that the sensitivity and specificity can be maximized by using probes 130-180 nucleotides long at a surface density in the range of 7 x 10 (-5)- 3 x 10(-4) probe molecules per nm(2). (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Theoretical study of kinetics of zipping phenomena in biomimetic polymers

PHYSICAL REVIEW E, 76(1).

By: A. Jayaraman n, E. Santiso n , C. Hall n  & J. Genzer n 

MeSH headings : Biomimetic Materials / chemistry; Computer Simulation; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Polymers / chemistry
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Computer Simulation Study of Molecular Recognition in Model DNA Microarrays

Biophysical Journal, 91(6), 2227–2236.

By: A. Jayaraman n, C. Hall n  & J. Genzer n 

MeSH headings : Computer Simulation; DNA, Single-Stranded / chemistry; Kinetics; Models, Chemical; Monte Carlo Method; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis / methods; Sensitivity and Specificity; Thermodynamics
TL;DR: This work uses lattice Monte Carlo simulations to study the thermodynamics and kinetics of hybridization of single-stranded target genes in solution with complementary probe DNA molecules immobilized on a microarray surface and observes that probes 12-16 segments gave the highest specificity and sensitivity. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2005 journal article

Adsorption of comb copolymers on weakly attractive solid surfaces

JOURNAL OF CHEMICAL PHYSICS, 123(6).

By: A. Striolo *, A. Jayaraman n, J. Genzer n  & C. Hall n 

TL;DR: The simple models of comb copolymers with short side chains used here show properties similar to those of associating polymers and of globular proteins in aqueous solutions, and can be used as a first approximation to investigate the mechanism of adsorption of proteins onto hydrophobic surfaces. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Computer simulation study of pattern transfer in AB diblock copolymer film adsorbed on a heterogeneous surface

JOURNAL OF CHEMICAL PHYSICS, 123(12).

By: A. Jayaraman n, C. Hall n  & J. Genzer n 

MeSH headings : Adsorption; Chemistry, Physical / methods; Computer Simulation; Models, Statistical; Molecular Conformation; Monte Carlo Method; Polymers / chemistry; Surface Properties
TL;DR: This work investigates how a pattern imposed in a copolymer film at a certain distance from the surface propagates through the film onto an adsorbing heterogeneous surface and explains why a certain pattern size is transferred to the surface with higher fidelity than the others. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Designing pattern-recognition surfaces for selective adsorption of copolymer sequences using lattice Monte Carlo simulation

PHYSICAL REVIEW LETTERS, 94(7).

By: A. Jayaraman n, C. Hall n  & J. Genzer n 

MeSH headings : Adsorption; Biocompatible Materials / chemistry; Computer Simulation; Models, Chemical; Molecular Conformation; Monte Carlo Method; Polymers / chemistry; Surface Properties
TL;DR: A simulation method to design surfaces for recognizing specific monomer sequences in copolymers and finding an optimal surface pattern that can recognize and selectively adsorb the sequence in the copolymer is described. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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