Tissue self-organization underlies morphogenesis of the notochord
Norman, J., Sorrell, E. L., Hu, Y., Siripurapu, V., Garcia, J., Bagwell, J., … Bagnat, M. (2018, September 24). Philosophical Transactions of the Royal Society B Biological Sciences, Vol. 373, p. 20170320.
author keywords: zebrafish; notochord; vacuolated cells; packing; self-organization
MeSH headings : Animals; Cell Count; Embryonic Development; Models, Biological; Morphogenesis; Notochord / embryology; Zebrafish / embryology
topics (OpenAlex): Cellular Mechanics and Interactions; Microtubule and mitosis dynamics; Caveolin-1 and cellular processes
TL;DR:
It is concluded that self-organization underlies morphogenesis of the vertebrate notochord, a conserved axial structure that in vertebrates serves as a hydrostatic scaffold for embryonic axis elongation and, later on, for proper spine assembly.
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