Eugene T. Won

Works (4)

Updated: July 5th, 2023 15:50

2016 journal article

Leptin stimulates hepatic growth hormone receptor and insulin-like growth factor gene expression in a teleost fish, the hybrid striped bass

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 229, 84–91.

By: E. Won n, J. Douros n, D. Hurt n & R. Borski n

author keywords: Leptin; Growth hormone receptor; GHR; Insulin-like growth factor; IGF; Growth; Teleost; Fish; Hepatocyte
MeSH headings : Animals; Bass / metabolism; Gene Expression Regulation / drug effects; Growth Hormone / metabolism; Leptin / metabolism; Liver / metabolism; Receptors, Somatotropin / genetics; Somatomedins / metabolism
TL;DR: The studies suggest that stimulation of growth axis component transcripts by leptin may be an important mechanism for coordinating somatic growth with nutritional state in these and perhaps other fish or vertebrates, and represent the first evidence of leptin regulating GHRs in vertebrates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Cloning and characterization of leptin in a Perciform fish, the striped bass (Morone saxatilis): Control of feeding and regulation by nutritional state

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 178(1), 98–107.

By: E. Won n, D. Baltzegar n, M. Picha n & R. Borski n

author keywords: Leptin; Phylogeny; Gene duplication; Perciform; Striped bass
MeSH headings : Animals; Bass / genetics; Bass / metabolism; Eating / drug effects; Leptin / genetics; Leptin / metabolism; Leptin / pharmacology
TL;DR: The results suggest that leptin may play a role in energy homeostasis in these advanced Perciformes, the largest and most diverse order of fish. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Ontogenesis of Gonadal Aromatase Gene Expression in Atlantic Silverside (Menidia menidia) Populations With Genetic and Temperature-Dependent Sex Determination

JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 313A(7), 421–431.

By: T. Duffy *, M. Picha n, E. Won n, R. Borski n, A. McElroy* & D. Conover *

MeSH headings : Animals; Aromatase / genetics; Aromatase / metabolism; Embryo, Nonmammalian / embryology; Embryo, Nonmammalian / physiology; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gonads / embryology; Gonads / enzymology; Hermaphroditic Organisms; Hot Temperature; Male; Sex Determination Processes; Sex Differentiation; Smegmamorpha / embryology; Smegmamorpha / physiology
TL;DR: The hypothesis that P450arom is involved in female sex differentiation in this species, but is only responsive to temperature in M. menidia populations that exhibit TSD is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Plasma ghrelin and growth hormone regulation in response to metabolic state in hybrid striped bass: Effects of feeding, ghrelin and insulin-like growth factor-I on in vivo and in vitro GH secretion

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 161(3), 365–372.

By: M. Picha n, C. Strom n, L. Riley*, A. Walker*, E. Won n, W. Johnstone n, R. Borski n

author keywords: Hybrid striped bass; Teleost; Growth hormone regulation; Ghrelin; Insulin-like growth factor-I
MeSH headings : Animals; Bass / blood; Fasting / physiology; Female; Ghrelin / blood; Ghrelin / metabolism; Ghrelin / pharmacology; Growth Hormone / blood; Growth Hormone / metabolism; In Vitro Techniques; Insulin-Like Growth Factor I / pharmacology; Male; Pituitary Gland / drug effects; Pituitary Gland / metabolism
TL;DR: These studies are the first to show that seasonally-based periods of feed deprivation and low temperature yield sustained increases in GH secretion that are likely mediated, at least partially, through elevated ghrelin, reduced IGF-I negative feedback and fasting-induced spontaneous GH release. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

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