Works (59)
Updated: April 6th, 2024 05:01
2024 article
Test-retest reliability of a mobile application of the patient reported outcomes burdens and experiences (PROBE) study
Curtis, R., Wu, J., Iorio, A., Frick, N., Nichol, M., Noone, D., … Germini, F. (2024, March 4). HAEMOPHILIA.
author keywords: haemophilia; mobile application; patient reported outcome; quality of life; questionnaire; reliability
Source: Web Of Science
Added: April 1, 2024
2023 journal article
Case Article—Bayer New Drug Development Decision Making
INFORMS Transactions on Education.
TL;DR:
The interactive case study requires student teams to engage with the instructor using a structured decision analysis process in deciding whether to develop a new drug to treat blood clots in legs to improve the analytical, modeling, and consulting skills of the students.
(via Semantic Scholar)
doi.org (publisher)
Source: ORCID
Added: November 4, 2021
2023 journal article
Case—Bayer New Drug Development Decision Making
INFORMS Transactions on Education.
Source: ORCID
Added: November 4, 2021
2023 article
Reported prevalence of von Willebrand disease worldwide in relation to income classification
Stonebraker, J. S., Iorio, A., Lavin, M., Rezende, S. M., Srivastava, A., Pierce, G. F., … Makris, M. (2023, June 5). HAEMOPHILIA, Vol. 6.
author keywords: epidemiology; national registry; prevalence; prevalence at birth; type 3 VWD; von Willebrand disease; WFH Annual Global Survey
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 8, 2023
2023 article
Von Willebrand disease: Gaining a global perspective
Jamie M. M. O'Sullivan, Tootoonchian, E., Ziemele, B., Makris, M., Federici, A. B. B., Djambas, C. K., … Lavin, M. (2023, May 22). HAEMOPHILIA, Vol. 5.
author keywords: bleeding disorder; diagnosis; registration; von Willebrand disease; von Willebrand factor
TL;DR:
Identifying the number of persons with VWD (PwVWD) internationally will help target support to aid diagnosis and management of von Willebrand Disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 12, 2023
2021 article
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time
Stonebraker, J. S., O'Mahony, B., Noone, D., & Iorio, A. (2021, June 17). HAEMOPHILIA, Vol. 6.
author keywords: annual global survey; conversion factors; EHL; emicizumab; Haemophilia; SHL
MeSH headings : Benchmarking; Blood Coagulation Factors / therapeutic use; Factor VIII / therapeutic use; Half-Life; Hemophilia A / drug therapy; Humans
TL;DR:
A method of converting IU of SHL or EHL, and milligrams of emicizumab into a single metric will facilitate benchmarking across different countries or longitudinally irrespective of the case-mix of treatment options.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 18, 2021
2021 article
Evaluation of the sexual health in people living with hemophilia
Germini, F., Chai-Adisaksopha, C., Pete, D., Curtis, R., Frick, N., Nichol, M. B., … Iorio, A. (2021, September 19). HAEMOPHILIA, Vol. 9.
author keywords: hemophilia; patient reported outcome; sexual health
MeSH headings : Adolescent; Adult; Aged; Hemarthrosis; Hemophilia A / complications; Hemophilia B / complications; Hemophilia B / epidemiology; Humans; Range of Motion, Articular; Sexual Health
TL;DR:
Knowledge about sexual health, difficulty with sexual activity and intimacy, in people with hemophilia is little understood.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 8, 2021
2021 journal article
Modelling future usage and cost of factor and emicizumab to treat haemophilia A for the US Western States Region IX haemophilia treatment centres
Haemophilia, 27(1).
author keywords: cost; decision analysis; emicizumab; epidemiology; haemophilia A; treatment; usage
MeSH headings : Antibodies, Bispecific; Antibodies, Monoclonal, Humanized; Factor VIII; Hemophilia A / drug therapy; Humans; Retrospective Studies
TL;DR:
Increased usage of emicizumab in the United States will affect standard half‐life (SHL) and extended half-life (EHL) products usage and cost.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: October 5, 2020
2021 journal article
Non‐severe haemophilia: Is it benign? – Insights from the PROBE study
Haemophilia, 9.
author keywords: bleeding; haemophilia; pain; patient-reported outcome
MeSH headings : Activities of Daily Living; Cross-Sectional Studies; Female; Health Status; Hemophilia A / complications; Humans; Male; Quality of Life
TL;DR:
There are limited data on the impact of haemophilia on health status and health‐related quality of life (HRQL) in people with non‐severe (mild and moderate) haemaphilia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: September 2, 2020
2021 journal article
Risk Analysis, Practice, and Considerations in Capital Budgeting: Evidence from the Field for the Bio-based Industry
BIORESOURCES, 16(1), 19–45.
Contributors: C. Assis n
author keywords: Financial risk analysis; Capital budgeting; Investment assessment; Project evaluation; Bioeconomy; Bio-based industry; Biomaterials
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 22, 2021
2020 journal article
The World Federation of Hemophilia Annual Global Survey 1999‐2018
Haemophilia.
author keywords: annual global survey; bleeding disorder; haemophilia; von Willebrand disease
MeSH headings : Adolescent; Cross-Sectional Studies / methods; Delivery of Health Care / standards; Developing Countries / economics; Developing Countries / statistics & numerical data; Factor VIII / therapeutic use; Female; HIV Infections / epidemiology; Healthcare Disparities / statistics & numerical data; Hemophilia A / diagnosis; Hemophilia A / drug therapy; Hemophilia A / epidemiology; Hemophilia A / prevention & control; Hepatitis C / epidemiology; Humans; International Cooperation / legislation & jurisprudence; Male; Organizations / organization & administration; Prevalence; Severity of Illness Index; Young Adult; von Willebrand Diseases / diagnosis; von Willebrand Diseases / epidemiology; von Willebrand Diseases / prevention & control
TL;DR:
The World Federation of Hemophilia strives to achieve care for all patients with inherited bleeding disorders through research, advocacy, capacity building and education.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: June 5, 2020
2019 journal article
Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males A Meta-analytic Approach Using National Registries
ANNALS OF INTERNAL MEDICINE, 171(8), 540-+.
MeSH headings : Australia / epidemiology; Canada / epidemiology; France / epidemiology; Hemophilia A / epidemiology; Humans; Infant, Newborn; Italy / epidemiology; Life Expectancy; Male; New Zealand / epidemiology; Prevalence; Registries; United Kingdom / epidemiology
TL;DR:
Establishing an accurate estimate of the number of persons with hemophilia in each setting of interest and worldwide is a necessary first step toward measuring the associated burden of disease, which is important in comparing and contrasting the adequacy of health care systems across countries and levels of wealth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 28, 2019
2019 journal article
Exploring regional variations in the cross-cultural, international implementation of the Patient Reported Outcomes Burdens and Experience (PROBE) study
HAEMOPHILIA, 25(3), 365–372.
author keywords: haemophilia; patient-reported outcome; quality of life; variance
MeSH headings : Adult; Cross-Cultural Comparison; Female; Hemophilia A / epidemiology; Hemophilia A / ethnology; Humans; Internationality; Male; Middle Aged; Patient Reported Outcome Measures; Surveys and Questionnaires
TL;DR:
The Patient Reported Outcomes Burdens and Experience (PROBE) study has developed and validated the PROBE questionnaire for assessing patient‐reported outcomes in people with haemophilia and participants without bleeding disorders.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2019
2019 journal article
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains
HAEMOPHILIA, 25(1), 75–83.
author keywords: haemophilia; patient-reported outcome; quality of life; reliability
MeSH headings : Adolescent; Adult; Aged; Blood Coagulation Disorders, Inherited / economics; Blood Coagulation Disorders, Inherited / psychology; Cost of Illness; Female; Health Status; Humans; Male; Middle Aged; Patient Reported Outcome Measures; Quality of Life; Surveys and Questionnaires; Young Adult
TL;DR:
The Patient Reported Outcomes, Burdens and Experiences (PROBE) study aims to develop and validate questionnaire for assessing health status in patients with haemophilia and participants without bleeding disorders.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 11, 2019
2018 journal article
Latent therapeutic demand model for the immunoglobulin replacement therapy of primary immune deficiency disorders in the USA
Vox Sanguinis.
author keywords: decision analysis; epidemiology; latent therapeutic demand; primary immune deficiency; treatment
TL;DR:
A USA‐specific LTD model for common variable immune deficiency (CVID), hyper IGM syndrome, severe combined immune deficiency, Wiskott–Aldrich syndrome and X‐linked agammaglobulinemia (XLA) is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: August 30, 2019
2018 journal article
Occurrence and impact of pain among patients living with hemophilia: An analysis from the patient reported outcomes, burdens and experiences (PROBE) study
Haemophilia, 24(S1), 26–27.
Source: NC State University Libraries
Added: September 8, 2019
2018 journal article
Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire
BMJ OPEN, 8(8).
author keywords: validity; hemophilia; patient reported outcome; quality of life; questionnaire
MeSH headings : Adult; Blood Coagulation Disorders / psychology; Blood Coagulation Disorders / therapy; Cost of Illness; Cross-Sectional Studies; Factor Analysis, Statistical; Female; Hemophilia A / psychology; Hemophilia A / therapy; Humans; Male; Patient Reported Outcome Measures; Psychometrics; Surveys and Questionnaires
TL;DR:
The results of this study suggest thatPROBE is a valid questionnaire for evaluating PROs in people with haemophilia as well as control population and the known-group property of PROBE will allow its use in future clinical trials, longitudinal studies, health technology assessment studies, routine clinical care or registries.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2018
2018 journal article
The Effect of Inhibitors on Quality of Life and Pain in Adult Patients with Severe Haemophilia in the PROBE Cohort
Research and Practice in Thrombosis Haemostasis, 2(S1), 76–77.
Source: NC State University Libraries
Added: September 8, 2019
2018 journal article
The PROBE Data Dashboard - A new tool for real-time data visualization and analysis of patient reported outcomes
Haemophilia, 24, 181–182.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
The PROBE Study –Global burden of bleeding from the mouth in Haemophilia – a call to action
Haemophilia, 24(S5), 66.
Source: NC State University Libraries
Added: September 8, 2019
2018 journal article
The Patient Reported Outcomes, Burdens and Experiences (PROBE) Project: development and evaluation of a questionnaire assessing patient reported outcomes in people with haemophilia
Pilot and Feasibility Studies, 4(1), 118–119.
TL;DR:
The PROBE questionnaire assesses patient-important reported outcomes in PWH and control participants, with a demonstrated short completion time, and proved the feasibility to engage diverse patient communities in the structured generation of real-world outcome research at all stages.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: September 8, 2019
2017 journal article
Burden of Comorbid Diseases in Patients with Hemophilia: The Cross-Sectional Analysis of the Patient Reported Outcomes, Burden and Experiences (PROBE) Study
Blood, 130(S1), 3411.
Source: NC State University Libraries
Added: September 8, 2019
2017 journal article
Burden of comorbidities in persons living with haemophilia: insight from the PROBE phase 2b study database
Research and Practice in Thrombosis Haemostasis, 1(S1), 840–841.
Source: NC State University Libraries
Added: September 8, 2019
2017 journal article
Estimating the global annual bleed rate in haemophilia
Haemophilia, 23, 86–86.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Psychometric Properties of the Patient Reported Outcomes Burdens and Experiences (PROBE) Questionnaire
Blood, 130(S1), 5645.
Source: NC State University Libraries
Added: September 8, 2019
2017 journal article
Sexual Health in Patients with Hemophilia; The Insights from the Patient Reported Outcomes, Burdens and Experiences (PROBE) Study
Blood, 130(S1), 2141.
Source: NC State University Libraries
Added: September 8, 2019
2017 journal article
Test-retest reliability analysis of the Patient Reported Outcomes Burdens and Experiences (PROBE) study
Haemophilia, 23(S2), 50–51.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Measuring the quality of haemophilia care across different settings: a set of performance indicators derived from demographics data
Haemophilia, 23(1), e1–e7.
author keywords: haemophilia; health care; incidence; prevalence
MeSH headings : Adolescent; Adult; Child; Child, Preschool; Demography; Female; Hemophilia A / therapy; Humans; Infant; Male; Middle Aged; Quality of Health Care; Young Adult
TL;DR:
This work proposes data‐driven indicators as surrogate measures for the provision of haemophilia care across countries and over time and shows clear trends in quality of care over time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Psychometric Test-Retest Reliability Analysis of the Patient Reported Outcomes Burdens and Experiences (PROBE)
Blood, 128(22), 5964.
Source: NC State University Libraries
Added: September 8, 2019
2016 conference paper
The Patient Reported Outcomes, Burdens, and Experiences (PROBE) Phase 1
HTAi 2016 Annual Meeting Abstract Book, 63–64.
Source: NC State University Libraries
Added: September 8, 2019
2016 journal article
The Patient Reported Outcomes, Burdens, and Experiences (PROBE) Phase 1 Study Methodology and Feasibility
Haemophilia, 22(S2), 43–44.
Source: NC State University Libraries
Added: September 8, 2019
2016 journal article
The patient reported outcome burdens and experiences (PROBE) study - phase 1 results show PROBE study methodology feasible
Journal of Thrombosis and Haemostasis, 14(S1), 47.
Source: NC State University Libraries
Added: September 8, 2019
2015 conference paper
How to measure progress in the provision of care for hemophilia
The Proceedings of the World Federation of Hemophilia’s Ninth Global Forum on Research and Treatment Products for Bleeding Disorders, 16–17.
Event: World Federation of Hemophilia’s Ninth Global Forum on Research and Treatment Products for Bleeding Disorders
Source: NC State University Libraries
Added: March 9, 2021
2014 journal article
Modeling Primary Immunodeficiency Disease Epidemiology and Its Treatment to Estimate Latent Therapeutic Demand for Immunoglobulin
JOURNAL OF CLINICAL IMMUNOLOGY, 34(2), 233–244.
author keywords: Primary immune deficiency; epidemiology.; treatment; decision analysis; latent therapeutic demand
MeSH headings : Adolescent; Adult; Agammaglobulinemia / epidemiology; Agammaglobulinemia / therapy; Aged; Aged, 80 and over; Child; Child, Preschool; Common Variable Immunodeficiency / epidemiology; Common Variable Immunodeficiency / therapy; Female; Genetic Diseases, X-Linked / epidemiology; Genetic Diseases, X-Linked / therapy; Humans; Immunoglobulins / administration & dosage; Immunoglobulins / therapeutic use; Immunologic Deficiency Syndromes / epidemiology; Immunologic Deficiency Syndromes / therapy; Male; Middle Aged; Models, Statistical; Monte Carlo Method; Prevalence; Young Adult
TL;DR:
The concept of latent therapeutic demand (LTD) was used to estimate evidence-based requirements and compared to the actual Ig consumption in different countries, finding the potential demand for treating CVID and XLA exceeds the currently observed usage of Ig in these disorders.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 conference paper
A decision analysis model to estimate latent therapeutic demand for immunoglobulin therapy in primary immunodeficiencies
Proceedings of the 15th Meeting of the European Society Immunodeficiencies (ESID), 29–34.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Product-Generation Transition Decision Making for Bayer's Hemophilia Drugs: Global Capacity Expansion Under Uncertainty with Supply-Demand Imbalances
OPERATIONS RESEARCH, 61(5), 1119–1133.
TL;DR:
This decision analysis developed an improved approach to Bayer's decision for product-generation transition and global production capacity expansion that more realistically addresses potential regional supply shortages and overages due to demand and supply uncertainties that can result in supply-demand imbalances.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
A study of variations in the reported haemophilia B prevalence around the world
HAEMOPHILIA, 18(3), e91–e94.
author keywords: epidemiology; haemophilia B; prevalence
MeSH headings : Global Health / economics; Global Health / statistics & numerical data; Hemophilia B / epidemiology; Humans; Income / classification; Male; Prevalence
TL;DR:
It was showed that the HB prevalence varied considerably among countries, even among the wealthiest of countries, and there was a strong trend of increasing HB prevalence over time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Decision analysis model for estimating latent therapeutic demand for immunoglobulin therapy in primary immune deficiencies
Journal of Clinical Immunology, 32(S1), 18.
Event: 15th Biennial Meeting of the European Society for Immunodeficiency
Source: NC State University Libraries
Added: March 9, 2021
2012 journal article
Impact factor as a metric to assess journals where OM research is published
JOURNAL OF OPERATIONS MANAGEMENT, 30(1-2), 24–43.
Contributors: n , E. Gil *, C. Kirkwood* & R. Handfield n
author keywords: Operations management; Production operations management; Impact factor; Citation analysis; Journal ranking
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2011 journal article
A study of reported factor IX use around the world
HAEMOPHILIA, 17(3), 446–455.
author keywords: factor IX; haemophilia B
MeSH headings : Delivery of Health Care; Developed Countries / economics; Developing Countries / economics; Drug Utilization; Factor IX / therapeutic use; Global Health; Hemophilia A / drug therapy; Humans; Income
TL;DR:
Trends suggest that the reported FIX usage increases with increasing economic capacity and has been increasing over time, and there will likely be an overall increase in the amount of FIX concentrates used in the treatment of haemophilia B.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 chapter
Empirically Investigating the Portfolio Management Process: Findings from a Large Pharmaceutical Company
In Portfolio Decision Analysis (pp. 131–148).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2011 journal article
NC State's Supply Chain Resource Cooperative Educates in the Real World
INTERFACES, 41(6), 548–563.
Contributors: R. Handfield n , S. Edwards n & n
author keywords: education; field-based student projects; supply chain applications
TL;DR:
The SCRC brings the classroom into industry and involving students in finding viable solutions to real business problems, thus facilitating interactions between students and companies and provide insights that may help other institutions interested in establishing similar organizations.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2011 journal article
Practice Summaries: American Airlines Uses Should-Cost Modeling to Assess the Uncertainty of Bids for Its Full-Truckload Shipment Routes
INTERFACES, 41(2), 194–196.
author keywords: decision analysis: applications; cost analysis; industries: transportation/shipping
TL;DR:
A probabilistic model was developed to help American Airlines assess the uncertainty of bid quotes for its full-truckload point-to-point freight shipments of maintenance equipment and in-flight service items in the United States.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
A study of reported factor VIII use around the world
HAEMOPHILIA, 16(1), 33–46.
author keywords: economics; factor VIII (FVIII) use; FVIII concentrate; haemophilia A; national healthcare planning; production planning; World Federation of Hemophilia
MeSH headings : Delivery of Health Care; Developed Countries / economics; Developing Countries / economics; Drug Utilization; Factor VIII / administration & dosage; Global Health; Hemophilia A / drug therapy; Humans; Income
TL;DR:
The results show that FVIII use varies considerably among countries, even among the wealthiest of countries, and that there probably will be a global increase in FV III concentrates usage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
A study of variations in the reported haemophilia A prevalence around the world
HAEMOPHILIA, 16(1), 20–32.
author keywords: economics; epidemiology; haemophilia A; prevalence; World Federation of Hemophilia
MeSH headings : Developed Countries / economics; Developing Countries / economics; Global Health; Hemophilia A / epidemiology; Humans; Income; Prevalence
TL;DR:
It was found that the reported haemophilia A prevalence varied considerably among countries, even among the wealthiest of countries, and manufacturers plan the production of concentrates and prevent future shortages.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Factor Usage - Global Data.
The Proceedings of the World Federation of Hemophilia’s Sixth Global Forum on the Safety and Supply of Hemophilia Treatment Products for Bleeding Disorders – Making the Case for Clotting Factor Concentrates, 9–11.
Event: World Federation of Hemophilia’s Sixth Global Forum on the Safety and Supply of Hemophilia Treatment Products for Bleeding Disorders
Source: NC State University Libraries
Added: March 9, 2021
2009 journal article
OR Practice—Modeling Potential Demand for Supply-Constrained Drugs: A New Hemophilia Drug at Bayer Biological Products
Operations Research, 57(1), 19–31.
TL;DR:
A novel approach to forecasting drug demand in markets where supply limitations have significantly curtailed sales volumes and thus reduced the usefulness of conventional sales-based forecasting methods, which can be very useful in helping both drug manufacturers and health-care agencies worldwide to ensure adequate supplies of critical drugs.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2007 chapter
Balancing Environmental and Operational Objectives in Nuclear Refueling Strategies
In W. Edwards, R. F. Miles Jr, & D. von Winterfeldt (Eds.), Advances in Decision Analysis (pp. 564–581).
Ed(s): W. Edwards, R. Miles & D. von Winterfeldt
Sources: Crossref, NC State University Libraries
Added: February 28, 2021
2007 conference paper
Understanding the supply-demand-price conundrum in the FVIII market
The Proceedings of the World Federation of Hemophilia’s Fifth Global Forum on the Safety and Supply of Hemophilia Treatment Products, 20–21.
Event: World Federation of Hemophilia’s Fifth Global Forum on the Safety and Supply of Hemophilia Treatment Products
Source: NC State University Libraries
Added: March 9, 2021
2004 journal article
Modelling haemophilia epidemiology and treatment modalities to estimate the unconstrained factor VIII demand
Haemophilia, 10(1), 18–26.
MeSH headings : Adolescent; Adult; Age Distribution; Body Weight; Child; Child, Preschool; Decision Making; Factor VIII / immunology; Factor VIII / supply & distribution; Factor VIII / therapeutic use; Hemophilia A / epidemiology; Hemophilia A / immunology; Hemophilia A / prevention & control; Humans; Immune Tolerance; Infant; Infant, Newborn; Infusions, Intravenous; Prevalence
TL;DR:
A new method for estimating the unconstrained factor VIII (FVIII) demand based on the principles of decision analysis is presented, which should help prevent shortages of FVIII concentrates such as those that have occurred in the past.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2003 journal article
A country-by-country comparison of FVIII concentrate consumption and economic capacity for the global haemophilia community
Haemophilia, 9(3), 245–250.
author keywords: developing world; factor VIII concentrates; health economics
MeSH headings : Developing Countries / economics; Drug Utilization; Factor VIII / administration & dosage; Health Care Costs; Health Care Rationing; Hemophilia A / drug therapy; Humans; Income; Male
TL;DR:
A method was presented to estimate the level of factor VIII (FVIII) concentrate consumption and economic capacity for each of the 110 countries considered in the study so each country can assess and compare its level of FVIII concentrate consumption with the economic resources of other countries in the global haemophilia A community.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2003 conference paper
Probabilistic Modelling of population-based epidemiology and treatment modalities to determine unconstrained factor VIII demand
Journal of Thrombosis and Haemostasis, 1(S1), P1645.
Event: XIX International Congress at Birmingham, UK on July 12-18, 2003
Source: NC State University Libraries
Added: March 18, 2021
2002 journal article
How Bayer Makes Decisions to Develop New Drugs
Interfaces, 32(6), 77–90.
author keywords: decision analysis : applications industries : pharmaceutical
TL;DR:
This commercial evaluation of a new blood-clot-busting drug was Bayer Pharmaceuticals' first decision analysis project and institutionalized decision analysis at the business-unit level.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2001 journal article
New York Power Authority Uses Decision Analysis to Schedule Refueling of Its Indian Point 3 Nuclear Power Plant
Interfaces, 31(5), 121–135.
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
1997 journal article
Formulating and solving sequential decision analysis models with continuous variables
IEEE Transactions on Engineering Management, 44(1), 43–53.
author keywords: continuous variables; decision analysis; government; model formulation; R&D planning; resource allocation; strategic planning
TL;DR:
The continuous-variable version of this model more directly represents the structure of the decision than a discrete approximation, and the resulting model can be efficiently solved using standard nonlinear optimization methods.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
1997 journal article
Practice Abstract: Decision Analysis Provides Insight to Ford Microelectronics Incorporated
Interfaces, 27(2), 107–111.
Source: NC State University Libraries
Added: March 18, 2021
1996 conference paper
It’s Time to Think About Values First
Quality Air Force in the 21st Century: Technology & Innovation 1996 Quality Air Force Symposium Proceedings, 78–88. Maxwell Air Force Base, AL: Air Force Quality Institute.
Event: 1996 Quality Air Force Symposium
Source: NC State University Libraries
Added: March 18, 2021
1991 conference paper
Can source selection benefit from decision analysis?
Acquisition Research Symposium Proceedings, 287–298.
Event: Acquisition Research Symposium at Washington, DC
Source: NC State University Libraries
Added: March 18, 2021
1991 journal article
Simon says: Rational decision-making for source selection
Program Manager: Journal of the Defense Systems Management College, 20(5), 34–40.
Source: NC State University Libraries
Added: March 18, 2021
Employment
Updated: July 30th, 2016 20:16
North Carolina State University Raleigh, US
Associate Professor
Business Management
Education
Updated: July 30th, 2016 20:15
University of South Florida Tampa, US
B.S.E.E. (Electrical Engineering)
Arizona State University Tempe, US
Ph.D. Business Administration
Stanford University Stanford, US
M.S. (Engineering-Economic Systems)
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