Norman J. Glassbrook

Works (8)

Updated: July 5th, 2023 15:55

2014 journal article

Lrp13 is a novel vertebrate lipoprotein receptor that binds vitellogenins in teleost fishes

JOURNAL OF LIPID RESEARCH, 55(11), 2287–2295.

By: B. Reading n , N. Hiramatsu*, J. Schilling n, K. Molloy n, N. Glassbrook n, H. Mizuta *, W. Luo *, D. Baltzegar n ...

author keywords: affinity purification; egg; endocytosis; oocyte; oogenesis; ovary; vitellogenesis; very low density lipoprotein receptor; yolk; low density lipoprotein receptor-related protein 13
MeSH headings : Animals; Bass; Cloning, Molecular; Fish Proteins / chemistry; Fish Proteins / genetics; Fish Proteins / metabolism; Gene Expression Regulation; Humans; Intracellular Space / metabolism; Protein Binding; Protein Transport; Receptors, Lipoprotein / chemistry; Receptors, Lipoprotein / genetics; Receptors, Lipoprotein / metabolism; Vitellogenins / metabolism
TL;DR: The Lrp13 appears to function as a vitellogenin receptor and may be an important mediator of yolk formation in fishes and other oviparous vertebrates and the presence of lp13 orthologs in mammals suggests that this lipoprotein receptor is widely distributed among vertebrates, where it may generally play a role in lipop protein metabolism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Multiple vitellogenins and product yolk proteins in striped bass, Morone saxatilis: molecular characterization and processing during oocyte growth and maturation

FISH PHYSIOLOGY AND BIOCHEMISTRY, 40(2), 395–415.

By: V. Williams n, B. Reading n , N. Hiramatsu*, H. Amano*, N. Glassbrook n, A. Hara*, C. Sullivan n

author keywords: Striped bass; Vitellogenin; Yolk; Post-vitellogenic oocytes; Ovulated eggs; Maturation; Mass spectrometry
MeSH headings : Amino Acid Sequence; Animals; Bass / genetics; Bass / growth & development; Bass / metabolism; Blotting, Western; Cloning, Molecular; DNA, Complementary / genetics; Egg Proteins / genetics; Egg Proteins / metabolism; Female; Fish Proteins / genetics; Fish Proteins / metabolism; Male; Molecular Sequence Data; Oocytes / growth & development; Oocytes / metabolism; Peptide Fragments / genetics; Peptide Fragments / metabolism; Phylogeny; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Tandem Mass Spectrometry; Vitellogenesis; Vitellogenins / genetics; Vitellogenins / metabolism
TL;DR: The detailed characterization of Vtgs and their proteolytic fate(s) during oocyte growth and maturation establishes striped bass as a freshwater model for investigating teleost multiple Vtg systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster

Genetics, 197(2), 781–630.

By: L. Reed, K. Lee, Z. Zhang, L. Rashid, A. Poe, B. Hsieh, N. Deighton, N. Glassbrook, R. Bodmer, G. Gibson

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Modulation of the phenylacetic acid metabolic complex by quinic acid alters the disease-causing activity of Rhizoctonia solani on tomato

Phytochemistry, 89, 47–52.

By: F. Bartz n, N. Glassbrook n, D. Danehower n & M. Cubeta n 

author keywords: Solanum lycopersicum L.; Solanaceae; Tomato; Rhizoctonia solani; Basidiomycota; Fungi; Gas chromatography-mass spectrometry; Bioassay; Host response; Phenylacetic acid; Quinic acid; Plant disease; Phenylalanine metabolism
MeSH headings : Solanum lycopersicum / microbiology; Phenylacetates / chemistry; Phenylacetates / metabolism; Plant Diseases / microbiology; Plant Growth Regulators / biosynthesis; Plant Growth Regulators / chemistry; Quinic Acid / pharmacology; Rhizoctonia / drug effects; Rhizoctonia / growth & development; Rhizoctonia / metabolism; Rhizoctonia / physiology
TL;DR: The results of this study support the hypotheses that utilization of QA by R. solani leads to reduced production of the plant growth regulators belonging to the PAA metabolic complex which can suppress plant disease development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Elucidating the role of the phenylacetic acid metabolic complex in the pathogenic activity of Rhizoctonia solani anastomosis group 3

MYCOLOGIA, 104(4), 793–803.

By: F. Bartz*, N. Glassbrook*, D. Danehower* & M. Cubeta* 

author keywords: aggressiveness; benzeneacetic acid; GC-MS; host response; Thanatephorus; virulence factor
MeSH headings : Culture Media; Gas Chromatography-Mass Spectrometry; Host-Parasite Interactions; Solanum lycopersicum / growth & development; Solanum lycopersicum / microbiology; Mycelium / growth & development; Phenylacetates / metabolism; Plant Diseases / microbiology; Plant Roots / microbiology; Plant Stems / microbiology; Rhizoctonia / growth & development; Rhizoctonia / metabolism; Rhizoctonia / pathogenicity; Seedlings / growth & development
TL;DR: The results of this investigation add to the body of evidence that the PAA metabolic complex is involved in Rhizoctonia disease development but do not indicate that production of these compounds is the primary or the only determinant of pathogenicity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Mannitol biosynthesis is required for plant pathogenicity by Alternaria alternata

FEMS MICROBIOLOGY LETTERS, 285(1), 122–129.

By: H. Veleaz, N. Glassbrook n & M. Daub n

author keywords: mannitol metabolism; reactive oxygen species; antioxidant; plant disease
MeSH headings : Alternaria / genetics; Alternaria / growth & development; Alternaria / metabolism; Alternaria / pathogenicity; Fungal Proteins / genetics; Fungal Proteins / metabolism; Mannitol / metabolism; Plant Diseases / microbiology; Spores, Fungal / genetics; Spores, Fungal / growth & development; Spores, Fungal / metabolism; Spores, Fungal / pathogenicity; Sugar Alcohol Dehydrogenases / genetics; Sugar Alcohol Dehydrogenases / metabolism; Tobacco / microbiology; Trehalose / metabolism
TL;DR: It is concluded that mannitol biosynthesis is required for pathogenesis of A. alternata on tobacco, but is not required for spore germination either in vitro or in planta or for initial infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Quantification of urinary aflatoxin B-1 dialdehyde metabolites formed by aflatoxin aldehyde reductase using isotope dilution tandem mass spectrometry

CHEMICAL RESEARCH IN TOXICOLOGY, 21(3), 752–760.

By: D. Johnson n, P. Egner n, G. OBrian n, N. Glassbrook n, B. Roebuck n, T. Sutter  n, G. Payne n, T. Kensler  n, J. Groopman n

MeSH headings : Aflatoxin B1 / urine; Aldehyde Reductase / metabolism; Aldehydes / metabolism; Animals; Carcinogens / metabolism; Chromatography, Affinity; Chromatography, High Pressure Liquid; Diet; Escherichia coli / metabolism; Glucuronidase / urine; Male; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Reference Standards; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Sulfatases / urine
TL;DR: This highly sensitive and specific isotope dilution method is applicable to in vivo quantification of urinary alcohol products produced by AFAR and contributes to the goal of mass balancing the fate of the bioreactive 8,9-epoxides of AFB 1 in vivo. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Mannitol metabolism in the phytopathogenic fungus Alternaria alternata

FUNGAL GENETICS AND BIOLOGY, 44(4), 258–268.

By: H. Velez  n, N. Glassbrook n & M. Daub n

author keywords: mannitol cycle; mannitol dehydrogenase; mannitol 1-phosphate 5-dehydrogenase; polyols; fungi
MeSH headings : Alternaria / enzymology; Alternaria / growth & development; Culture Media; Fungal Proteins / genetics; Fungal Proteins / metabolism; Gene Deletion; Genes, Fungal; Mannitol / metabolism; Mannitol Dehydrogenases / genetics; Mannitol Dehydrogenases / metabolism; Plant Diseases / microbiology; Substrate Specificity; Sugar Alcohol Dehydrogenases / genetics; Sugar Alcohol Dehydrogenases / metabolism; Tobacco / microbiology
TL;DR: Enzymatic assays demonstrate that mannitol 1-phosphate 5-dehydrogenase and mann Capitol dehydrogenase are essential enzymes inMannitol metabolism in A. alternata, but do not support mannitor metabolism operating as a cycle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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