Works (11)
Updated: July 31st, 2023 18:05
1991 journal article
EFFECTS OF A ZINC-DEFICIENT DIET ON TISSUE ZINC CONCENTRATIONS IN RABBITS
JOURNAL OF ANIMAL SCIENCE, 69(12), 4876–4882.
author keywords: ZINC; RABBITS; EYES
MeSH headings : Administration, Oral; Animals; Bone and Bones / chemistry; Brain Chemistry; Eye / chemistry; Hair / chemistry; Lens, Crystalline / chemistry; Lens, Crystalline / pathology; Liver / chemistry; Male; Rabbits / growth & development; Rabbits / metabolism; Testis / chemistry; Testis / pathology; Thymus Gland / pathology; Zinc / administration & dosage; Zinc / analysis; Zinc / blood; Zinc / deficiency
TL;DR:
Young male New Zealand White rabbits given a diet containing 2 ppm of Zn (Zn-deficient diet) ceased to grow after 5 wk and exhibited alopecia, skin lesions, and frequent pasteurella infections, which were not observed in rabbits fed the other diets.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1986 journal article
Effects of melittin on a model renal epithelium, the toad urinary bladder
Biochimica Et Biophysica Acta, 855, 63–67.
MeSH headings : Amiloride / pharmacology; Animals; Bee Venoms / pharmacology; Bufo marinus; Epithelium / drug effects; Kidney / cytology; Lanthanum / pharmacology; Meclofenamic Acid / pharmacology; Melitten / pharmacology; Membrane Potentials / drug effects; Models, Biological; Urinary Bladder / cytology; Urinary Bladder / drug effects
TL;DR:
The bee venom melittin, 10(-6) M, on the mucosal (urinary) side of the toad urinary bladder (in vitro), markedly decreased transepithelial potential difference, short-circuit current (Isc, sodium-dependent) and resistance.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
1985 journal article
Melittin-induced changes in Na and Cl movements across toad's skin and cornea (in vitro) of the toad, Bufo marinus
Comparative Biochemistry and Physiology, 291–296.
MeSH headings : Amphotericin B / pharmacology; Animals; Bee Venoms / pharmacology; Biological Transport, Active / drug effects; Bufo marinus; Bumetanide / pharmacology; Chlorides / metabolism; Cornea / drug effects; Cornea / metabolism; Meclofenamic Acid / pharmacology; Melitten / pharmacology; Quinacrine / pharmacology; Skin / drug effects; Skin / metabolism; Sodium / metabolism; Trifluoperazine / pharmacology; Vasopressins / pharmacology
TL;DR:
Melittin apparently has two types of effects, one mediated by prostaglandins while the other is more direct, as shown in corneas with melittin on the inside and on the tear side of the cornea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
1983 journal article
CALCIUM-METABOLISM OF THE RABBIT LENS
EXPERIMENTAL EYE RESEARCH, 36(1), 57–66.
MeSH headings : Animals; Calcium / metabolism; Calcium-Binding Proteins / metabolism; Hydrogen-Ion Concentration; In Vitro Techniques; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Male; Osmolar Concentration; Rabbits
TL;DR:
Efflux of Ca from the lens was unchanged, under experimental conditions, by metabolic inhibitors, by EGTA, verapamil, TFP and vanadate, and in the presence of metabolic inhibitors (iodoacetate plus cyanide) lenticular Ca rises.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
1983 journal article
SOME OBSERVATIONS ON THE MAGNESIUM-METABOLISM OF THE RABBIT LENS
EXPERIMENTAL EYE RESEARCH, 36(1), 67–73.
MeSH headings : Animals; Calcimycin / pharmacology; In Vitro Techniques; Lens Cortex, Crystalline / drug effects; Lens Nucleus, Crystalline / drug effects; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Magnesium / metabolism; Male; Osmolar Concentration; Rabbits
TL;DR:
Incubation of lenses in solutions containing EDTA or following freezing and thawing suggested that much of the Mg is present in a bound form, and adjustment of the external Mg level in the presence of A-23187 indicated that the internal 'free' Mg concentration was about 3 mM, suggesting that about 35% of the lenticular magnesium is bound.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
1982 journal article
A PHARMACOLOGICAL ANALYSIS OF CHLORIDE TRANSPORT ACROSS THE AMPHIBIAN CORNEA
JOURNAL OF PHYSIOLOGY-LONDON, 325(APR), 481–492.
MeSH headings : 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / analogs & derivatives; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / pharmacology; Animals; Biological Transport, Active / drug effects; Bucladesine / pharmacology; Bufo marinus; Bumetanide / pharmacology; Calcimycin / pharmacology; Chlorides / metabolism; Cornea / metabolism; Dinoprostone; Epinephrine / pharmacology; In Vitro Techniques; Meclofenamic Acid / pharmacology; Models, Biological; Prostaglandins E / pharmacology; Quinacrine / pharmacology; Trifluoperazine / pharmacology
TL;DR:
Active Cl, but not Na, transport across the toad cornea was inhibited by mepacrine, which is a phospholipase A2 inhibitor; trifluoperazine, which blocks the action of calmodulin; and meclofenamic acid, which inhibits synthesis of prostaglandins.
(via Semantic Scholar)
open access via physoc.onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1982 journal article
STIMULATION OF TRANS-EPITHELIAL SODIUM AND CHLORIDE TRANSPORT BY ASCORBIC-ACID - INDUCTION OF NA+ CHANNELS IS INHIBITED BY AMILORIDE
BIOCHIMICA ET BIOPHYSICA ACTA, 689(2), 385–392.
MeSH headings : Amiloride / pharmacology; Animals; Ascorbic Acid / pharmacology; Biological Transport, Active / drug effects; Bufo marinus; Chlorides / metabolism; Cornea / metabolism; Epithelium / drug effects; Epithelium / metabolism; Ion Channels / drug effects; Ion Channels / metabolism; Kinetics; Pyrazines / pharmacology; Sodium / metabolism
TL;DR:
The effect of ascorbic acid on Isc when it was on the aqueous humor side of the cornea could be blocked by bumetanide but that due to the vitamin's presence on the tear side was unchanged, and these effects were additive.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1981 journal article
Alpha-aminoisobutyric acid transport in the amphibian crystalline lens
Journal of Physiology (London), 34, 49–56.
Source: NC State University Libraries
Added: August 6, 2018
1981 journal article
INHIBITION OF ALPHA-AMINOISOBUTYRIC-ACID UPTAKE BY DIISOTHIOCYANOSTILBENEDISULPHONIC ACID IN THE AMPHIBIAN CORNEA
BIOCHIMICA ET BIOPHYSICA ACTA, 643(1), 261–264.
MeSH headings : 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid / analogs & derivatives; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / analogs & derivatives; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / pharmacology; Alanine / metabolism; Aminoisobutyric Acids / metabolism; Animals; Biological Transport / drug effects; Bufo marinus; Cornea / metabolism; Hydrogen-Ion Concentration; Kinetics; Lens, Crystalline / metabolism; Stilbenes / pharmacology
TL;DR:
The inhibitory effect of diisothiocyanostilbenedisulphonic acid on aminoisobutyric acid accumulation appears to reflect a direct action on membrane mechanisms that mediate its influx.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1980 journal article
INHIBITORY-ACTION OF DIDS ON CHLORIDE TRANSPORT ACROSS THE AMPHIBIAN CORNEA
JOURNAL OF PHYSIOLOGY-LONDON, 304(JUL), 519–527.
MeSH headings : 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / analogs & derivatives; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / pharmacology; Animals; Biological Transport, Active / drug effects; Bufo marinus; Bumetanide / pharmacology; Chlorides / metabolism; Cornea / drug effects; Cornea / metabolism; In Vitro Techniques; Membrane Potentials / drug effects; Sodium / metabolism; Stilbenes / pharmacology
TL;DR:
The results are consistent with the role of a Cl‐/anion exchange mechanism in active Cl transport across the cornea and a hypothesis regarding the interactions and site of action of bumetanide in relation to that of DIDS, and the Cl transport process is proposed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1977 journal article
The mode of action of bumetanide: inhibition of chloride transport across the amphibian cornea
Journal of Pharmacology and Experimental Therapeutics, 203, 97–102.
Source: NC State University Libraries
Added: August 6, 2018
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