Shawn Marie Ballard

Works (1)

Updated: July 5th, 2023 15:41

2014 journal article

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

FOOD AND CHEMICAL TOXICOLOGY, 76, 19–26.

By: R. Church *, D. Gatti *, T. Urban*, N. Long*, . Yang *, Q. Shi *, J. Eaddy *, M. Mosedale * ...

author keywords: Green tea; Epigallocatechin gallate; Hepatotoxicity; Population variability; Herbal; Diversity outbred
MeSH headings : Animals; Antioxidants / administration & dosage; Antioxidants / adverse effects; Catechin / administration & dosage; Catechin / adverse effects; Catechin / analogs & derivatives; Chemical and Drug Induced Liver Injury / genetics; Chromosome Mapping; Dose-Response Relationship, Drug; Genotyping Techniques; In Situ Nick-End Labeling; Liver / drug effects; Liver / metabolism; Male; Mice / genetics; Phenotype; Polymorphism, Single Nucleotide; Polyphenols / administration & dosage; Polyphenols / adverse effects; Quantitative Trait Loci; Tea / chemistry
TL;DR: The data indicate that the Diversity Outbred mice may provide a platform for informing risk of rare, adverse reactions that may occur in consumer populations upon ingestion of concentrated herbal products. (via Semantic Scholar)
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Added: August 6, 2018

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