Works (1)

Updated: July 5th, 2023 15:41

2015 journal article

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice


By: R. Church*, D. Gatti*, T. Urban*, N. Long*, . Yang*, Q. Shi*, J. Eaddy*, M. Mosedale* ...

author keywords: Green tea; Epigallocatechin gallate; Hepatotoxicity; Population variability; Herbal; Diversity outbred
MeSH headings : Animals; Antioxidants / administration & dosage; Antioxidants / adverse effects; Catechin / administration & dosage; Catechin / adverse effects; Catechin / analogs & derivatives; Chemical and Drug Induced Liver Injury / genetics; Chromosome Mapping; Dose-Response Relationship, Drug; Genotyping Techniques; In Situ Nick-End Labeling; Liver / drug effects; Liver / metabolism; Male; Mice / genetics; Phenotype; Polymorphism, Single Nucleotide; Polyphenols / administration & dosage; Polyphenols / adverse effects; Quantitative Trait Loci; Tea / chemistry
TL;DR: The data indicate that the Diversity Outbred mice may provide a platform for informing risk of rare, adverse reactions that may occur in consumer populations upon ingestion of concentrated herbal products. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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