Wei Xiao

Works (3)

Updated: July 5th, 2023 15:43

2015 article

Benefits of Model-based Drug Development: A Rigorous, Planned Case Study

COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION, Vol. 44, pp. 2210–2222.

By: R. Reeve*, S. Berry*, W. Xiao n, B. Ferguson n, M. Thuerk & R. Goetz

author keywords: Adaptive trial; Bayesian; Dose response; Model-based drug development; Phase I; Phase II
TL;DR: The conclusion is that the use of MBDD could have facilitated more efficient use of resources in the traditional drug development process. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

ConvexLAR: An Extension of Least Angle Regression

JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS, 24(3), 603–626.

By: W. Xiao*, Y. Wu* & H. Zhou*

author keywords: Solution path; Group lasso; Regularization; Ordinary differential equation (ODE); Lasso
TL;DR: This article proposes a ConvexLAR algorithm that works for any convex loss function and naturally extends to group selection and data adaptive variable selection and yields new exact path algorithms for certain penalty methods such as a conveX loss function with lasso or group lasso penalty. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Rheumatoid Arthritis Disease Progression Modeling

THERAPEUTIC INNOVATION & REGULATORY SCIENCE, 47(6), 641–650.

By: R. Reeve*, L. Pang*, B. Ferguson n, M. O'Kelly, S. Berry* & W. Xiao n

author keywords: rheumatoid arthritis; time progression model; nonlinear model; ACR20; DMARD; TNF inhibitor
TL;DR: A meta-analysis of time progression models for rheumatoid arthritis shows that an exponential time response model adequately fits the data and a distribution of effects for biological RA therapies can be provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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