2024 article
Diagnostic challenge in veterinary pathology: Tri-cavitary effusion in a cat with systemic pyogranulomatous inflammation
Fingerhood, S., Neupane, P., Breitschwerdt, E. B., & Choi, E. A. (2024, January 21). VETERINARY PATHOLOGY.
An approximately 2-month-old, domestic shorthair cat presented to the University of California, Davis Veterinary Medical Teaching Hospital for lethargy, hyporexia, and increased respiratory rate and effort of a few days duration.Clinically, there was tri-cavitary effusion; the pleural effusion, interpreted as a borderline modified transudate, had a nucleated cell count of 130/µl (43% neutrophils, 29% small mononuclear cells, 28% large mononuclear cells), a total protein of 2.5 g/dl, and frequent erythrophagia.Complete blood count abnormalities included an inflammatory leukogram with a left shift (4680 band/µl, 120 metamyelocytes/µl), toxic neutrophils, and a nonregenerative anemia (17.2% hematocrit [30%-50%]).Serum biochemical abnormalities included hypoglobulinemia (2.0 g/dl [2.8-5.4]) with a low-normal albumin (2.4 g/dl [2.2-4.6]),hyponatremia (133 mmol/l [151-158]), hypokalemia (3.1 mmol/l [3.6-4.9]),hypochloremia (101 mmol/l [117-126]), hypophosphatemia (3 mg/dl [3.2-6.3]), and hypoglycemia (59 mg/dl [63-118]).Pleural fluid was quantitative PCR negative for feline coronavirus (feline infectious peritonitis [FIP]), and a feline leukemia virus antigen SNAP test (IDEXX Laboratories, Westbrook, ME, USA) was negative.Echocardiography and chest radiographs did not identify congenital cardiac abnormalities.Due to a guarded prognosis, humane euthanasia was elected.