2021 journal article
Deciphering Pyrrolidine and Olefin Formation Mechanism in Kainic Acid Biosynthesis
ACS CATALYSIS, 11(1), 278–282.
author keywords: metalloenzyme; C-H activation; cyclization; desaturation; enzyme mechanism
TL;DR:
A comparison of C–H bond activation and cyclization in the isodomoic acid and kainic acid biosynthesis experiments shows that the former is superior to the latter in terms of both molecular complexity and physical properties.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 15, 2021
Metalloenzyme-catalyzed cyclization involving C–H bond activation is a powerful strategy to construct molecular complexity found in natural product biosynthesis. In the isodomoic acid and kainic ac...