2021 journal article
A defect in the NOG gene increases susceptibility to spontaneous superficial chronic corneal epithelial defects (SCCED) in boxer dogs
BMC VETERINARY RESEARCH, 17(1).
author keywords: Corneal ulcer; Chronic; Superficial; Recurrent erosion; NOG; Boxer
MeSH headings : Animals; Bone Morphogenetic Proteins / genetics; Bone Morphogenetic Proteins / metabolism; Chronic Disease; Corneal Diseases / veterinary; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Epithelium, Corneal / pathology; Gene Expression Regulation; Genetic Predisposition to Disease; Whole Genome Sequencing
TL;DR:
Many Boxer dogs with SCCED have a genetic defect in NOG, a constitutive protein in the cornea which is a potent inhibitor of BMP, which likely regulate limbal epithelial progenitor cells (LEPC).
(via Semantic Scholar)
bmcvetres.biomedcentral.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 9, 2021
Abstract