Works (6)

Updated: July 5th, 2023 15:52

2011 journal article

Architecture of energy balance traits in emerging lines of the Collaborative Cross

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 300(6), E1124–E1134.

By: W. Mathes*, D. Aylor*, D. Miller*, G. Churchill*, E. Chesler*, F. Villena*, D. Threadgill n, D. Pomp*

author keywords: genetics; wheel running; adiposity; body weight; quantitative trait loci
MeSH headings : Alleles; Analysis of Variance; Animals; Body Fat Distribution; Body Weight / genetics; Body Weight / physiology; Chromosome Mapping; Chromosomes / genetics; Crosses, Genetic; Eating / genetics; Eating / physiology; Energy Metabolism / genetics; Energy Metabolism / physiology; Genotype; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity / physiology; Phenotype; Physical Conditioning, Animal / physiology; Quantitative Trait Loci; Running / physiology; Sample Size
TL;DR: The results suggest that the CC will be a powerful, high-precision tool for examining the genetic architecture of complex traits such as those involved in regulation of energy balance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
7. Affordable and Clean Energy (OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Dietary Fat Alters Body Composition, Mammary Development, and Cytochrome P450 Induction after Maternal TCDD Exposure in DBA/2J Mice with Low-Responsive Aryl Hydrocarbon Receptors

ENVIRONMENTAL HEALTH PERSPECTIVES, 117(9), 1414–1419.

By: M. La Merrill*, B. Kuruvilla*, D. Pomp*, L. Birnbaum* & D. Threadgill n

author keywords: aryl hydrocarbon receptor; fetal loss; gene-environment interactions; mouse; obesity; 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
MeSH headings : Animals; Body Composition; Cytochrome P-450 Enzyme System / biosynthesis; Dietary Fats / administration & dosage; Enzyme Induction; Female; Mammary Glands, Animal / growth & development; Mammary Glands, Animal / metabolism; Maternal Exposure; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Polychlorinated Dibenzodioxins / toxicity; Pregnancy; Receptors, Aryl Hydrocarbon / metabolism
TL;DR: D2 progeny fed a diet similar to that consumed by most people are susceptible to TCDD and DMBA exposure effects blood glucose levels, mammary differentiation, and hepatic Cyp1 expression. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1991 journal article

GENETIC-VARIATION IN REPRODUCTIVE RESPONSES TO A HIGH-ENERGY DIET IN MICE

JOURNAL OF ANIMAL SCIENCE, 69(5), 1875–1884.

By: D. Pomp n & E. Eisen n

author keywords: FLUSHING; GENETIC VARIATION; OVULATION RATE; EMBRYO MORTALITY; SELECTION; MICE
MeSH headings : Animals; Body Weight / genetics; Eating; Energy Intake; Female; Genetic Variation; Least-Squares Analysis; Litter Size / genetics; Male; Mice / genetics; Ovulation / genetics; Random Allocation; Regression Analysis; Reproduction / genetics
TL;DR: Significant genetic variation in reproductive responses to a high-energy diet in mice is indicated, with effects of HED on embryo survival rate and ovulation rate significantly negative in L+ and L+W-; the decrease in L-W- was a result of preimplantation losses, and the increase in L+. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1991 journal article

VARIATION AMONG DONOR FEMALES IN MAMMALIAN PREIMPLANTATION EMBRYO RESEARCH

THERIOGENOLOGY, 35(6), 1209–1224.

By: D. Pomp n & E. Eisen n

author keywords: EMBRYOS; EXPERIMENTAL DESIGN; STATISTICAL ANALYSIS
TL;DR: Data from two investigations involving preimplantation mouse embryo survival rates were analyzed by statistical methods which considered (Analysis I) or ignored (Analysis II) variation among-donor females, yielding conservative tests of hypotheses relative to analyses which ignored this source of variation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1990 journal article

GENETIC-CONTROL OF SURVIVAL OF FROZEN MOUSE EMBRYOS

BIOLOGY OF REPRODUCTION, 42(5-6), 775–786.

By: D. Pomp n & E. Eisen n

MeSH headings : Animals; Blastocyst / cytology; Blastocyst / physiology; Body Weight; Crosses, Genetic; Embryo, Mammalian / physiology; Female; Genotype; Male; Mice; Mice, Inbred ICR / genetics; Pregnancy; Random Allocation; Species Specificity
TL;DR: Results demonstrate significant correlated responses in embryo post-thaw cryosurvival due to selection, and implicate both maternal and embryonic genomes as controlling mouse embryo cryosURvival. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1988 journal article

Cryopreservation of mammalian embryos

ISI Atlas of Science, 1(1), 40.

By: D. Pomp & J. Critser

Source: NC State University Libraries
Added: August 6, 2018

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