Works (2)
Updated: July 5th, 2023 15:51
2010 journal article
Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid β-oxidation in liver of neonatal swine
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 298(5), R1435–R1443.
author keywords: acetate; anaplerosis; carnitine palmitoyltransferase I activity; ketone bodies; mitochondria; Sus scrofa
MeSH headings : Acetates / metabolism; Acetyl-CoA Hydrolase / metabolism; Age Factors; Animals; Animals, Suckling; Carbon Radioisotopes; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Citric Acid / metabolism; Citric Acid Cycle / physiology; Enzyme Activation / physiology; Fatty Acids / metabolism; Gene Expression Regulation, Enzymologic; Ketone Bodies / metabolism; Liver / enzymology; Malonyl Coenzyme A / metabolism; Mitochondria / metabolism; Mitochondria, Liver / enzymology; Oxidation-Reduction; Palmitates / pharmacokinetics; Palmitoyl Coenzyme A / metabolism; RNA, Messenger / metabolism; Sus scrofa / metabolism
TL;DR:
It is demonstrated that acetate is the primary product of hepatic mitochondrial beta-oxidation in Sus scrofa and that regulation during early development is mediated primarily via kinetic modulation of CPT I.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2008 journal article
Maternal Dietary L-Carnitine Supplementation Influences Fetal Carnitine Status and Stimulates Carnitine Palmitoyltransferase and Pyruvate Dehydrogenase Complex Activities in Swine
The Journal of Nutrition, 138(12), 2356–2362.
MeSH headings : Animals; Carnitine / administration & dosage; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Dietary Supplements; Energy Metabolism / drug effects; Female; Fetus / metabolism; Kinetics; Liver / enzymology; Maternal-Fetal Exchange; Myocardium / enzymology; Pregnancy; Pyruvate Dehydrogenase Complex / metabolism; Swine
TL;DR:
Carnitine ingestion during pregnancy increases fetal carnitine concentrations and stimulates heart PDHC and liver CPT activity without altering Carnitine K(m).
(via Semantic Scholar)
open access via jn.nutrition.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
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