Works (2)

Updated: July 5th, 2023 15:51

2010 journal article

Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid β-oxidation in liver of neonatal swine

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 298(5), R1435–R1443.

By: X. Lin n, K. Shim n & J. Odle n

Contributors: X. Lin n, K. Shim n & J. Odle n

author keywords: acetate; anaplerosis; carnitine palmitoyltransferase I activity; ketone bodies; mitochondria; Sus scrofa
MeSH headings : Acetates / metabolism; Acetyl-CoA Hydrolase / metabolism; Age Factors; Animals; Animals, Suckling; Carbon Radioisotopes; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Citric Acid / metabolism; Citric Acid Cycle / physiology; Enzyme Activation / physiology; Fatty Acids / metabolism; Gene Expression Regulation, Enzymologic; Ketone Bodies / metabolism; Liver / enzymology; Malonyl Coenzyme A / metabolism; Mitochondria / metabolism; Mitochondria, Liver / enzymology; Oxidation-Reduction; Palmitates / pharmacokinetics; Palmitoyl Coenzyme A / metabolism; RNA, Messenger / metabolism; Sus scrofa / metabolism
TL;DR: It is demonstrated that acetate is the primary product of hepatic mitochondrial beta-oxidation in Sus scrofa and that regulation during early development is mediated primarily via kinetic modulation of CPT I. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Maternal Dietary L-Carnitine Supplementation Influences Fetal Carnitine Status and Stimulates Carnitine Palmitoyltransferase and Pyruvate Dehydrogenase Complex Activities in Swine

The Journal of Nutrition, 138(12), 2356–2362.

By: L. Xi n, K. Brown*, J. Woodworth*, K. Shim n, B. Johnson* & J. Odle n

Contributors: L. Xi n, K. Brown*, J. Woodworth*, K. Shim n, B. Johnson* & J. Odle n

MeSH headings : Animals; Carnitine / administration & dosage; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Dietary Supplements; Energy Metabolism / drug effects; Female; Fetus / metabolism; Kinetics; Liver / enzymology; Maternal-Fetal Exchange; Myocardium / enzymology; Pregnancy; Pyruvate Dehydrogenase Complex / metabolism; Swine
TL;DR: Carnitine ingestion during pregnancy increases fetal carnitine concentrations and stimulates heart PDHC and liver CPT activity without altering Carnitine K(m). (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

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