William Stephen McCall, Jr.

Works (2)

Updated: July 19th, 2023 12:35

2009 article

Synthesis of 1,3-Amino Alcohol Derivatives via a Silicon-Mediated Ring-Opening of Substituted Piperidines

McCall, W. S., & Comins, D. L. (2009, June 11). Organic Letters.

By: W. McCall n & D. Comins n

MeSH headings : Amino Alcohols / chemical synthesis; Amino Alcohols / chemistry; Cyanogen Bromide / chemistry; Molecular Structure; Piperidines / chemistry; Stereoisomerism; Trimethylsilyl Compounds / chemistry
topics (OpenAlex): Advanced Synthetic Organic Chemistry; Synthetic Organic Chemistry Methods
TL;DR: Multisubstituted piperidines containing a trimethylsilylmethyl group at C-2 can be opened regioselectively with TBAF and cyanogen bromide for stereoselective synthesis of alkylamine derivatives containing multiple chiral centers. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2008 article

N-Acyldihydropyridones as Synthetic Intermediates. A Stereoselective Synthesis of Acyclic Amino Alcohols Containing Multiple Chiral Centers

McCall, W. S., Grillo, T. A., & Comins, D. L. (2008, November 13). The Journal of Organic Chemistry.

By: W. McCall n, T. Grillo n & D. Comins n

MeSH headings : Amino Alcohols / chemical synthesis; Amino Alcohols / chemistry; Catalysis; Cyanogen Bromide / chemistry; Hydrogenation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Conformation; Piperidines / chemistry; Spectrophotometry, Infrared; Stereoisomerism
topics (OpenAlex): Chemical synthesis and alkaloids; Advanced Synthetic Organic Chemistry; Synthesis and Catalytic Reactions
TL;DR: Various multisubstituted piperidines containing a phenyl group at C-2 can be opened regio- and stereoselectively with cyanogen bromide to create uniquely substituted alkylamine derivatives containing multiple chiral centers and various functionality. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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