John F. Roberts

Works (3)

Updated: July 5th, 2023 16:03

2000 journal article

Question your statistical assumptions

Swine Health and Production, 8(5), 237.

By: J. Roberts

Source: NC State University Libraries
Added: August 6, 2018

1999 patent

Antibodies that selectively bind quadruplex nucleic acids

Washington, DC: U.S. Patent and Trademark Office.

By: C. Hardin, B. Brown, J. Roberts & S. Pelsue

Source: NC State University Libraries
Added: August 6, 2018

1998 review

Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune "viable motheaten" mice

[Review of ]. BIOCHEMISTRY, 37(46), 16325–16337.

By: B. Brown n, Y. Li n, J. Brown  n, C. Hardin n, J. Roberts n, S. Pelsue  n, L. Shultz  n

MeSH headings : Animals; Antibodies, Antinuclear / chemistry; Antibodies, Antinuclear / isolation & purification; Antibodies, Monoclonal / chemistry; Antibodies, Monoclonal / isolation & purification; Antibody Affinity / genetics; Antibody Specificity / genetics; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Base Sequence; Binding Sites, Antibody / genetics; DNA / chemistry; DNA / immunology; DNA / metabolism; G-Quadruplexes; Hybridomas; Immunoglobulin G / metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes / immunology; Nucleic Acid Heteroduplexes / metabolism; Protein Conformation; Regression Analysis
TL;DR: In vitro radioimmunofilter binding experiments demonstrated that purified anti-DNA quadruplex antibodies from anti-quadruplex antibody-producing tissue culture supernatants have at least 10-fold higher affinity for quadruplexes than for triplex and duplex DNA structures of similar base composition and length. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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