Endothelin-1, endothelin converting enzyme-1 and endothelin receptors in the porcine corpus luteum
Zorrilla, L. M., Sriperumbudur, R., & Gadsby, J. E. (2009, September 19). Domestic Animal Endocrinology, Vol. 38, pp. 75–85.
author keywords: Pig; Luteolytic sensitivity; Endothelin; Corpus luteum; Prostaglandin-F-2 alpha; Luteolysis
MeSH headings : Animals; Aspartic Acid Endopeptidases / analysis; Aspartic Acid Endopeptidases / genetics; Corpus Luteum / chemistry; Dinoprost / pharmacology; Endothelial Cells / chemistry; Endothelin-1 / analysis; Endothelin-1 / genetics; Endothelin-1 / physiology; Endothelin-Converting Enzymes; Estrous Cycle; Female; Fluorescent Antibody Technique; Gene Expression; Luteal Cells / chemistry; Luteolysis / drug effects; Luteolysis / physiology; Metalloendopeptidases / analysis; Metalloendopeptidases / genetics; Protein Precursors / analysis; Protein Precursors / genetics; Receptor, Endothelin A / analysis; Receptor, Endothelin A / genetics; Receptor, Endothelin A / physiology; Receptors, Endothelin / analysis; Receptors, Endothelin / genetics; Reverse Transcriptase Polymerase Chain Reaction; Swine
topics (OpenAlex): Nitric Oxide and Endothelin Effects; Reproductive Physiology in Livestock; Veterinary Medicine and Surgery
TL;DR:
The observed elevation in ECE1 protein concentrations on day 10 and the presence of EDNRA on LLC suggests a possible role for EDN1 (resulting from the actions of E CE1) acting via EDN RA in the control of LS in the pig.
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